Abstract: A method of populating a digital environment with an anonymous humanoid digital character is disclosed. One or more values are randomly determined for one or more target human properties. An asset pool is searched for assets that are compatible with the one or more values. The assets include a human body mesh. A blend of height and weight vertex animation textures (VATs) is applied to the human body mesh. The blended human body mesh is placed into the digital environment.

Abstract: A system that can receive non-clinical data related to an individual from one or more third party servers, and clinical data for that individual from one or more healthcare systems. The system can also pre-processes the non-clinical data and the clinical data, such as, for example, reduce the cardinality of the data and standardize the formatting of the data. The system can further project a propensity of the individual for developing at least one chronic disease by correlating the non-clinical data with the clinical data. Further, the system can identify, for each chronic disease, non-clinical factors that positively or negatively affect the propensity of the individual to develop that chronic disease, and generate a portal for display a projection for the individual to develop the chronic disease(s). At least a portion of the non-clinical risk factors can be identified by the system distilling information from secondary guidelines.

Abstract: An exemplary compounding method of controlling a compounding device to prepare an admixture of at least two distinct material sources can include examining material source solutions for incompatibility of the ingredients and operating a first and a second pump to prevent one of the incompatible source solutions from entering a common flow path. The processing method can detect degradation of a fluid line by evaluating one or more of calibration error rate data, cumulative volumetric flow data, or cumulative pump operation data. The processing method can also selectively transfer a first group of source solutions using the first pump, receiving pump data from one or more sensors that sense actions of the pumps, applying fluid correction factors and calculating discrete pump movements, the pump movements being indicative of an amount of source solution displacement by a pump, and operating the pumps to selectively dispense the source solution amounts according to a preparation order.

Abstract: Embodiments of the invention provide a customizable bicycle saddle for a bicycle. The bicycle saddle has been designed to allow it to be adjusted to match the ischial tuberosities of each rider's pelvis in order to minimize the pressure placed on other portions of the rider's body while seated on the bicycle. The bicycle saddle comprises a first seating portion that has been configured to allow a rider to sit on the bicycle, a second seating portion that has been configured to allow the rider to sit on the bicycle. The bicycle saddle also includes a first adjustment means configured to allow the first seating portion to be moved closer to the second seating portion, and a second adjustment means configured to allow the saddle to be moved closer to a forward portion on the bicycle.

Abstract: Fragrance delivery devices are disclosed. The fragrance delivery devices are designed to couple with an existing air supply of a room, such as a patient care room, and utilize air flow from the existing air supply to disperse a fragrance-carrying fluid from the fragrance delivery device into a surrounding environment. Methods of making and using fragrance delivery devices are also disclosed.

Abstract: This invention relates to adjuvant formulations comprising various combinations of triterpenoids, sterols, immunomodulators, polymers, and Th2 stimulators; methods for making the adjuvant compositions; and the use of the adjuvant formulations in immunogenic and vaccine compositions with different antigens. This invention further relates to the use of the formulations in the treatment of animals.

Abstract: The present invention provides a stackable, space saving system of bowls which may form a three- or four-tiered tower of bowls that are stably locked upright in place using a twist and lock mechanism located on each of the bowls. The present invention also includes different-sized, molded, elongated elliptical members that telescopically fit one into the other so that the tower is collapsible into a compact, space-saving configuration. In addition, each bowl may be used singly and includes an accompanying airtight lid.

Abstract: A poppet valve apparatus has a valve body with an aperture rimmed by a first sealing surface, and a valve stem with an axially oriented cup at its tip with a spring disposed within the cup. The valve plate includes a sealing surface at its perimeter and also has a central pocket which receives a spheroid. The valve stem passes through a collar which is affixed to the valve plate to trap the spheroid beneath the spring so that the plate is pivotably coupled to the valve stem and also tolerates radial and lateral excursion to allow the valve plate to self-align and seal within the valve seat.

Abstract: A battery, for example, a rechargeable battery (e.g. lithium ion battery) having a casing with battery terminals. The casing, for example, includes an upper section, middle section, and lower section connected together. The battery can be connected to one or more battery trays having the same height or different heights for various applications.

Abstract: A module for constructing foundations for a structure, comprising: a plurality of formwork members that define a pair of side walls that define a space between the side walls; thereto to hold the side walls in a spaced relationship; a three dimensional reinforcement cage that includes the brace, a plurality of first members, and a plurality of second members perpendicular to the first members, the first members coupled to at least the brace and the second members coupled to at least one of the plurality of the first members and the brace, wherein the cage forms an internal support within the space between the side walls for receiving a settable material, such that the side walls become integrated with the internal support as the settable substrate sets, to form the module.

Abstract: A rechargeable battery assembly includes a rechargeable battery having a positive terminal and a negative terminal, and a rigid electrically conductive frame electrically connected to at least one of the positive terminal or the negative terminal of the rechargeable battery. The rigid electrically conductive frame is bent along multiple axes and includes a plurality of conductive frame members that are mechanically coupled together. The rigid electrically conductive frame surrounds the rechargeable battery on at least five sides, thereby providing structural stability to the rechargeable battery assembly during storage and use.

Abstract: A rechargeable battery jump starting device having detachable positive and negative cables. The rechargeable battery jump starting device, including a rechargeable battery connected to a positive cam-lock cable connecting device and a negative cam-lock cable connecting device. The rechargeable battery jump starting device can include a highly electrically conductive frame connecting the rechargeable battery to the cam-lock cable devices.

Abstract: A battery assembly device for a battery jump starting device. The battery assembly is configured to maximize electrical conductivity from a battery pack of the battery jump starting device to a battery to be recharged.

Abstract: A process is disclosed for creating a print profile to control the operation of a direct-to-shape printing system for applying images on the exterior of an axially symmetrical media object that has a contoured, varying exterior surface, such as occurs on curved wine bottles and sports equipment like bats. The process takes a media recipe holding media geometry information and an image intended to be printed and processes that information to control a motion control subsystem and a print engine subsystem. The geometry information is manipulated to generate a CAM table suitable for the motion control subsystem, and the image file is processed to create a raster image file suitable for ink head expression. Various setup values are included in the process to prepare the direct-to-shape printing system for use of the media recipe.

Abstract: The present invention provides methods of treating an immune system dysfunction or conditions associated with soluble BCMA using gamma secretase modulators or inhibitors in order to both restore immune function and improve the efficacy of therapies directed against BCMA present on the pathogenic B cell.

Abstract: Described herein are pharmaceutical compositions comprising 2-{5-[(3-ethoxypyridin-2-yl)oxy]pyridin-3-yl}-N-[(3S,5S)-5-fluoropiperidin-3-yl]pyrimidine-5-carboxamide, or pharmaceutically acceptable salt thereof, for treatment of liver disease and diseases related thereto. Also described are compositions comprising 2-{5-[(3-ethoxypyridin-2-yl)oxy]pyridin-3-yl}-N-[(3S,5S)-5-fluoropiperidin-3-yl]pyrimidine-5-carboxamide, or pharmaceutically acceptable salt thereof and 4-(4-(1-Isopropyl-7-oxo-1,4,6,7-tetrahydrospiro[indazole-5,4?-piperidine]-1?-carbonyl)-6-methoxypyridin-2-yl)benzoic acid, or pharmaceutically acceptable salt thereof, for treatment of liver disease and diseases related thereto.

Abstract: A series of substituted dicyclopropyl methyl derivatives as defined herein, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune disorders.