Abstract: Novel RET fusion molecules and uses are disclosed.

Abstract: Embodiments disclosed herein generally relate to multi-arm machine learning models for lesion detection. Particularly, aspects of the present disclosure are directed to accessing a three-dimensional magnetic resonance imaging (MRI) images. Each of the three-dimensional MRI images depict a same volume of a brain of a subject. The volume of the brain includes at least part of one or more lesions. Each three-dimensional MRI image of the three-dimensional MRI images is processed using one or more corresponding encoder arms of a machine-learning model to generate an encoding of the three-dimensional MRI image. The encodings of the three-dimensional MRI images are concatenated to generate a concatenated representation. The concatenated representation is processed using a decoder arm of the machine-learning model to generate a prediction that identifies one or more portions of the volume of the brain predicted to depict at least part of a lesion.

Abstract: The disclosure herein describes management of transaction blocking schemes via a user interface. A transaction blocking scheme is receiving via the user interface from a user, including transaction blocking rules. The transaction blocking rules are applied to transaction data associated with the user. Transaction blocking scheme performance data is generated based on the application of the transaction blocking rules to the transaction data, including a quantity of transactions of the transaction data that are blocked by the transaction blocking rules. A visualization of the transaction blocking scheme performance data is displayed via the user interface and the user is prompted to provide a response based on the displayed visualization. Based on the response to the prompt, the transaction blocking scheme is activated for application to incoming transactions, whereby the transaction blocking rules are applied to incoming transactions to determine whether to block the incoming transactions.

Abstract: Techniques for modifying a garment based on gestures are presented herein. An access module can access a first set of sensor data from a first sensor, and a second set of sensor data from a second sensor. A garment simulation module can generate a three-dimensional (3D) garment model of a garment available for sale draped on an avatar based on the first set of sensor data and the second set of sensor data. A display module can cause a presentation, on a display of a device, of the 3D garment model draped on the avatar. Additionally, the garment simulation module can determine a modification gesture associated with the 3D garment model draped on the avatar based on the first set of sensor data and the second set of sensor data. Furthermore, the garment simulation module can modify the 3D garment model based on the determined modification gesture.

Abstract: A method of analyzing a tumor sample comprising: (a) acquiring a library comprising a plurality of tumor members from a tumor sample; (b) contacting the library with a bait set to provide selected members; (c) acquiring a read for a subgenomic interval from a tumor member from said library; (d) aligning said read; and (e) assigning a nucleotide value (e.g., calling a mutation) from said read for the preselected nucleotide position, thereby analyzing said tumor sample.

Abstract: A system and method for operating a rotatable knob module with adjustable tactile feedback. The rotatable knob module includes a knob configured to continuously rotate about a center axis and an electronic processor. The electronic processor is configured to determine a current trailer angle, define a virtual center position of the knob based on the current trailer angle, and adjust a rotational torque of the knob when the knob is rotated from a first rotational position to a second rotational position based on a relative virtual rotational distance of the second rotational position from the virtual center position.

Abstract: A computer implemented method manages connections. A number of processor units monitor connection requests to access a set of backend resources. The number of processor units identify request groups for the connection requests based on authentication data in the connection requests. The number of processor units analyze the connection requests to identify a usage trend for connections by the request groups. The number of processor units predict the usage trend of the connections for a period of time to form a predicted usage trend for connections in the period of time. The number of processor units manage a connection pool based on the predicted usage trend for the connections in the period of time.

Abstract: Described embodiments provide systems and methods for an attachment mechanism for attaching a strap around a body extremity. The attachment mechanism includes a hook, a first channel, and a second channel. The hook includes a first longitudinal axis and coupled to the strap at a first region of the hook. The first channel allowing the attachment mechanism to receive the strap. The second channel extending from the first channel and having an opening allowing the attachment mechanism to secure the strap, the opening extending along a second longitudinal axis, the second longitudinal axis forming an angle of less than ninety degrees with the first longitudinal axis. The strap is coupled to a harness. The strap includes a first portion, an attachment portion attached to the first portion, a main portion attached to the attachment portion; and an elastic portion attached to the main portion.

Abstract: Systems, devices, and methods are disclosed for wireless communication of analyte data. In this regard, in embodiments, a mobile includes a transceiver configured to transmit and receive wireless signals. The mobile device includes circuitry operatively coupled to the transceiver. The mobile device also includes a non-transitory computer-readable medium operatively coupled to the circuitry and storing instructions that, when executed, cause the mobile device to perform a number of operations. One such operation is to obtain a derivative of a first signal received via a first link. Another such operation is to obtain a derivative of a second signal received via a second link; and. Yet another such operation is to generate a selection for connection to an analyte sensor system, based on a comparison of the derivative of the first signal and the derivative of the second signal.

Abstract: A system for removing, storing and precisely re-installing removable automobile doors. This system includes a mobile base for positioning near the vehicle and moving stored doors to their storage location. The base of this system provides mounting positions for 2 or more lifting/storing/re-installation devices, accommodating full service (removal, storage and re-installation) of up to 4 doors at once. The lifting/storage/re-installation devices contain full 3 axis precise adjustment and rigid coupling to each of the vehicle's doors. Without this precision, the weight and non-balance of removing/re-installing the doors can cause the door to tilt into or away from the vehicle, possibly crushing a human body part (finger, hand) and/or damaging the vehicle or door. By rigidly coupling the door to the precisely adjusted device, precise vertical lifting and lowering may be used to remove and re-install the doors, including accommodating surface variations encountered from removal to re-installation time.

Abstract: Systems, methods, apparatuses, and devices, for the wireless communication of analyte data are provided. In some embodiments, a method and calibration station for calibrating a continuous analyte sensor system is provided. Methods and testing systems for testing a continuous analyte sensor system is provided. Continuous analyte sensor systems, display devices and peripheral devices configured for wireless communication of analyte, connection, alarm and/or alert data and associated methods are provided.

Abstract: Novel NTRK1 fusion molecules, detection reagents, and uses and kits for evaluating, identifying, assessing and/or treating a subject having a cancer are disclosed.

Abstract: A heat exchange ribbon includes a base portion to be attached to a spacer to be mounted to a circuit board, a tail portion substantially parallel to the base portion, and a leg connecting the tail portion to the base portion. A height of the leg extends in the same direction as a height of the base portion and the tail portion so as to create an opening at least partially surrounded by the base portion, the leg, and the tail portion. The base portion, the tail portion, and the leg portion have a one-piece construction. The leg extends below a lower edge of the base portion such that at least a portion of the tail portion is located below a lower edge of the base portion, and at least a portion of an inner surface of the tail portion does not oppose the outer surface of the base portion.

Abstract: Systems and methods for determining an angle of a movement path of a trailer. The system for determining an angle of a movement path of a trailer comprises a camera; and an electronic controller communicatively coupled to the camera and configured to receive first data from the camera, determine an absolute angle of the trailer based on matching one portion of an image received in the first data to a template, receive second data from the camera, estimate a change in the angle of the trailer based on tracking one or more points on the trailer received in the second data, and determine the angle of the movement path of the trailer based upon the trailer angle and the change in the angle of the trailer.

Abstract: Techniques disclosed herein facilitate tracking the degree to which a size of a biological structure changes over time. In some instances, an initial biological image (collected at a first time) can be segmented to characterized a boundary and size. A subsequent biological image can be processed to identify a deformation and/or transformation variable (e.g., one or more Jacobian matrices and/or one or more Jacobian determinants). The deformation and/or transformation variable(s) and initial segmentation can be used to predict a size of the biological structure at a subsequent time. The predicted size may inform a treatment recommendation.

Abstract: Mechanisms are provided in a cloud-based computing environment for identifying sensitive data risks in cloud-based deployments. The mechanisms build a knowledge graph based on data schema information for a cloud-based computing environment, a set of parsed infrastructure logs, and a set of captured application queries. The mechanisms identify a set of sensitive flows in the knowledge graph representing paths from a sensitive data element to an endpoint in the knowledge graph. The mechanisms score the set of sensitive flows based on a scoring algorithm and issue an alert to an administrator in response to a score of a sensitive flow within the set of sensitive flows exceeding a threshold.

Abstract: Systems, methods, apparatuses, and devices, for the wireless communication of analyte data are provided. In some embodiments, a method and calibration station for calibrating a continuous analyte sensor system is provided. Methods and testing systems for testing a continuous analyte sensor system is provided. Continuous analyte sensor systems, display devices and peripheral devices configured for wireless communication of analyte, connection, alarm and/or alert data and associated methods are provided.

Abstract: The invention discloses a scanning method and apparatus suitable for scanning a pipeline or a process vessel in which a beam of gamma radiation from a source is emitted through the pipeline or the process vessel to be detected by an array of detectors, which are each collimated to detect gamma radiation over a narrow angle relative to a width of the emitted beam of gamma radiation.

Abstract: Content frames can be provided for productivity applications through a content frame platform. The platform can detect a sequence of similar documents (“a document run”) and provide functionality to easily create the next document in the sequence through a content frame. The platform can receive a trigger for a content frame for a new document; and, in response, determine whether the new document belongs to a document run. In response to determining the new document belongs to a document run, the platform can determine at least two documents in the document run to be used to create the content frame and identify common content between the at least two documents in the document run. The content frame, which can include at least an outline for the new document and sections of updatable content for the new document, can be generated using the common content and provided for display and/or editing.

Abstract: A torsion bar assembly comprises an input shaft, an output shaft, and a torsion bar that connects the input shaft to the output shaft. An end stop face on the input shaft that co-operates with a respective end stop face of the output shaft to limit an angular deflection of the torsion bar assembly in a first direction away from the neutral position and an end stop face on the input shaft that co-operates with a respective end stop face of the output shaft to limit an angular deflection of the torsion bar assembly in a second direction that opposes the first direction. A first alignment feature is provided at or close to the end of the input shaft nearest the output shaft and a second alignment feature is provided at or close to an end of the output shaft nearest to the input shaft, the first alignment feature facing the second alignment feature across a gap.