Patents by Inventor James A. Sutton
James A. Sutton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11927172Abstract: The invention provides a method of forming a wind turbine blade. The blade has a main blade module that defines a main body of the blade and includes a first mating feature, e.g. a tongue. The blade also includes a separate edge module that defines at least part of a trailing edge of the blade and includes a second mating feature, e.g. a recess. The method includes applying an adhesive to at least one of the first mating feature and the second mating feature. The method includes arranging the separate edge module relative to the main blade module such that the first and second mating features are mutually adjacent. The method includes applying a pressure force to squeeze the adhesive to bond the first and second mating features together. The pressure force is caused by removing air from, or injecting air into, an air sealed region.Type: GrantFiled: April 22, 2020Date of Patent: March 12, 2024Assignee: Vestas Wind Systems A/SInventors: Chris Sutton, Paul Lewis, James Olive, Steven Pascoe, Ashleigh Porter
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Publication number: 20240067333Abstract: A rotor blade for a rotary wing aircraft includes a leading edge and a trailing edge defining a chordwise direction. The leading edge defines a forward end of the rotor blade and the trailing edge defines an aft end of the rotor blade. The rotor blade has a center of gravity and an aerodynamic center along the chordwise direction. The center of gravity is aft of the aerodynamic center.Type: ApplicationFiled: August 31, 2022Publication date: February 29, 2024Applicant: LOCKHEED MARTIN CORPORATIONInventors: Joshua A. Breon, Eric S. Parsons, Christopher M. Sutton, William Paul Adams, Timothy James Conti, Jared Anapolle, Evan Medrano
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Patent number: 11680038Abstract: The present disclosure relates to fluid bed processes that utilize silica particles as a fluidization aid. The process comprises reacting one or more reactants in a reactor comprising a fluid bed to form a product. The fluid bed comprises a catalyst composition comprising a catalyst and an inert additive composition comprising silica particles from 0.5 wt % to 30 wt %, based on the total weight of the catalyst composition. The silica particles are discrete, inert particles that are mixed with the catalyst in the fluid bed.Type: GrantFiled: June 9, 2021Date of Patent: June 20, 2023Assignee: Ascend Performance Materials Operations LLCInventors: Yawu T. Chi, James Sutton, Ali Akhavan, Celia L. Kniepmann, Matthew D. Cox, Valerie S. Monical
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Publication number: 20220106276Abstract: Disclosed herein are certain 2-oxoquinazoline derivatives of Formula (IA): that are methionine adenosyltransferase 2A (MAT2A) inhibitors. Also disclosed are pharmaceutical compositions comprising such compounds and methods of treating diseases treatable by inhibition of MAT2A such as cancer, including cancers characterized by reduced or absence of methylthioadenosine phosphorylase (MTAP) activity.Type: ApplicationFiled: December 9, 2019Publication date: April 7, 2022Inventors: Muzaffar ALAM, Leah CLEARY, Melissa FLEURY, Zhonghua PEI, Richard STEEL, James SUTTON, John E. KNOX, Zachary E. R. NEWBY
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Publication number: 20210300862Abstract: The present disclosure relates to fluid bed processes that utilize silica particles as a fluidization aid. The process comprises reacting one or more reactants in a reactor comprising a fluid bed to form a product. The fluid bed comprises a catalyst composition comprising a catalyst and an inert additive composition comprising silica particles from 0.5 wt % to 30 wt %, based on the total weight of the catalyst composition. The silica particles are discrete, inert particles that are mixed with the catalyst in the fluid bed.Type: ApplicationFiled: June 9, 2021Publication date: September 30, 2021Applicant: Ascend Performance Materials Operations LLCInventors: Yawu T. CHI, James Sutton, Ali Akhavan, Celia L. Kniepmann, Matthew D. Cox, Valerie S. Monical
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Patent number: 11130759Abstract: Disclosed herein are certain 2-oxoquinazoline derivatives of Formula (IA): that are methionine adenosyltransferase 2A (MAT2A) inhibitors. Also disclosed are pharmaceutical compositions comprising such compounds and methods of treating diseases treatable by inhibition of MAT2A such as cancer, including cancers characterized by reduced or absence of methylthioadenosine phosphorylase (MTAP) activity.Type: GrantFiled: February 12, 2021Date of Patent: September 28, 2021Assignee: IDEAYA BIOSCIENCE, INC.Inventors: Muzaffar Alam, Leah Cleary, Melissa Fleury, Zhonghua Pei, Richard Steel, James Sutton, John E. Knox, Zachary E. R. Newby
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Patent number: 11084798Abstract: Disclosed herein are certain 2-oxoquinazoline derivatives of Formula (IA): that are methionine adenosyltransferase 2A (MAT2A) inhibitors. Also disclosed are pharmaceutical compositions comprising such compounds and methods of treating diseases treatable by inhibition of MAT2A such as cancer, including cancers characterized by reduced or absence of methylthioadenosine phosphorylase (MTAP) activity.Type: GrantFiled: February 12, 2021Date of Patent: August 10, 2021Assignee: IDEAYA BIOSCIENCES, INC.Inventors: Muzaffar Alam, Leah Cleary, Melissa Fleury, Zhonghua Pei, Richard Steel, James Sutton, John E. Knox, Zachary E. R. Newby
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Patent number: 11059774Abstract: The present disclosure relates to fluid bed processes that utilize silica particles as a fluidization aid. The process comprises reacting one or more reactants in a reactor comprising a fluid bed to form a product. The fluid bed comprises a catalyst composition comprising a catalyst and an inert additive composition comprising silica particles from 0.5 wt % to 30 wt %, based on the total weight of the catalyst composition. The silica particles are discrete, inert particles that are mixed with the catalyst in the fluid bed.Type: GrantFiled: June 27, 2019Date of Patent: July 13, 2021Assignee: Ascend Performance Materials Operations LLCInventors: Yawu T. Chi, James Sutton, Ali Akhavan, Celia L. Kniepmann, Matthew D. Cox, Valerie S. Monical
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Patent number: 11046691Abstract: Disclosed herein are certain 2-oxoquinazoline derivatives of Formula (IA): that are methionine adenosyltransferase 2A (MAT2A) inhibitors. Also disclosed are pharmaceutical compositions comprising such compounds and methods of treating diseases treatable by inhibition of MAT2A such as cancer, including cancers characterized by reduced or absence of methylthioadenosine phosphorylase (MTAP) activity.Type: GrantFiled: February 12, 2021Date of Patent: June 29, 2021Assignee: IDEAYA BIOSCIENCES, INC.Inventors: Muzaffar Alam, Leah Cleary, Melissa Fleury, Zhonghua Pei, Richard Steel, James Sutton, John E. Knox, Zachary E. R. Newby
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Publication number: 20210130547Abstract: The present disclosure relates to a process for preparing polymers using a plug flow reactor. The process includes providing an aqueous monomer solution comprising amide monomers; evaporating the aqueous monomer solution to form a concentrated monomer solution; and polymerizing the concentrated monomer solution in a plug flow reactor comprising a shell side and a tube side to form a first process fluid comprising polymers. The concentrated monomer solution flows on the shell side from the inlet to the outlet.Type: ApplicationFiled: January 15, 2021Publication date: May 6, 2021Applicant: Ascend Performance Materials Operations LLCInventors: James A. SUTTON, John M. ZABCIK, Chris SCHWIER, Cihan UZUNPINAR, Shahram AKBARI
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Patent number: 10824332Abstract: A method, a computer program product, and a device that includes one or more processors, a touchscreen, and an operating system. A first dialogue interface is displayed on the touchscreen for receiving user commands by a user touching the dialogue interface. Received user commands are ignored for a defined first period of time in response to the operating system causing a generation of a second dialogue interface on the touchscreen, wherein the defined first period of time is a function of a user interaction with the touch screen by the user.Type: GrantFiled: August 30, 2016Date of Patent: November 3, 2020Assignee: International Business Machines CorporationInventors: Paul M. R. Edmonds, Joe Pavitt, James E. Ravenscroft, James Sutton
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Patent number: 10733182Abstract: The invention provides a method of aggregate banding comprising defining an aggregate banding dimension for a first data source, the aggregate banding dimension including at least one aggregation variable, at least one banding variable, and at least one band based at least partly on the at least one banding variable; summarizing the data source based at least partly on the at least one aggregation variable, the summary including at least one distinct value of the at least one aggregation variable; and defining a mapping relationship of the at least one distinct value of the at least one aggregation variable to the or respective band(s) based on the value of the at least one banding variable. The invention further provides related systems and processor-executable instructions.Type: GrantFiled: December 10, 2013Date of Patent: August 4, 2020Assignee: Healthagen International LimitedInventors: Ian James Sutton, Syuzanna Vartkesovna Zakharova
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Patent number: 10537561Abstract: The present invention provides a compound of formula I; wherein R1 is an alkyl pyrazole or an alkyl carboxamide, and R2 is a hydroxycycloalkyl; or a pharmaceutically acceptable salt thereof, and compositions containing these compounds, for use to treat a brain tumor, particularly glioblastoma. The invention provides effective treatment of a brain tumor and can be used by oral administration of a compound of Formula I as further described herein. The invention also provides a method to treat a subject having a brain tumor such as glioblastoma, wherein the method comprises administering to the subject an effective amount of a compound of Formula I. Gene signatures correlated with successful treatment using these methods are also disclosed.Type: GrantFiled: June 4, 2018Date of Patent: January 21, 2020Assignees: Novartis AG, Sloan-Kettering Institute for Cancer ResearchInventors: Dylan Daniel, Johanna Joyce, James Sutton
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Publication number: 20200002271Abstract: The present disclosure relates to fluid bed processes that utilize silica particles as a fluidization aid. The process comprises reacting one or more reactants in a reactor comprising a fluid bed to form a product. The fluid bed comprises a catalyst composition comprising a catalyst and an inert additive composition comprising silica particles from 0.5 wt % to 30 wt %, based on the total weight of the catalyst composition. The silica particles are discrete, inert particles that are mixed with the catalyst in the fluid bed.Type: ApplicationFiled: June 27, 2019Publication date: January 2, 2020Applicant: Ascend Performance Materials Operations LLCInventors: Yawu T. CHI, James Sutton, Ali Akhavan, Celia L. Kniepmann, Matthew D. Cox, Valerie S. Monical
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Patent number: 10235162Abstract: A software program is executed, the software program requiring one or more physical interactions with a user through an input/output (I/O) device, wherein each of the one or more physical interactions includes respective predefined dimensions indicating a proficiency in performing one of the one or more physical interactions. The one or more physical interactions are tracked. A familiarity profile for each of the one or more physical interactions is generated based on the respective predefined dimensions for each of the one or more physical interactions. The software program is customized based on the familiarity profile for each of the one or more physical interactions.Type: GrantFiled: April 4, 2018Date of Patent: March 19, 2019Assignee: International Business Machines CorporationInventors: Paul M. R. Edmonds, Joe Pavitt, James E. Ravenscroft, James Sutton
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Patent number: 10198258Abstract: A software program is executed, the software program requiring one or more physical interactions with a user through an input/output (I/O) device, wherein each of the one or more physical interactions includes respective predefined dimensions indicating a proficiency in performing one of the one or more physical interactions. The one or more physical interactions are tracked. A familiarity profile for each of the one or more physical interactions is generated based on the respective predefined dimensions for each of the one or more physical interactions. The software program is customized based on the familiarity profile for each of the one or more physical interactions.Type: GrantFiled: April 4, 2018Date of Patent: February 5, 2019Assignee: International Business Machines CorporationInventors: Paul M. R. Edmonds, Joe Pavitt, James E. Ravenscroft, James Sutton
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Publication number: 20190030013Abstract: The present invention provides a compound of formula I; wherein R1 is an alkyl pyrazole or an alkyl carboxamide, and R2 is a hydroxycycloalkyl; or a pharmaceutically acceptable salt thereof, and compositions containing these compounds, for use to treat a brain tumor, particularly glioblastoma. The invention provides effective treatment of a brain tumor and can be used by oral administration of a compound of Formula I as further described herein. The invention also provides a method to treat a subject having a brain tumor such as glioblastoma, wherein the method comprises administering to the subject an effective amount of a compound of Formula I. Gene signatures correlated with successful treatment using these methods are also disclosed.Type: ApplicationFiled: June 4, 2018Publication date: January 31, 2019Inventors: Dylan Daniel, Johanna Joyce, James Sutton
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Patent number: 10175994Abstract: A method and apparatus for initiating secure operations in a microprocessor system is described. In one embodiment, one initiating logical processor initiates the process by halting the execution of the other logical processors, and then loading initialization and secure virtual machine monitor software into memory. The initiating processor then loads the initialization software into secure memory for authentication and execution. The initialization software then authenticates and registers the secure virtual machine monitor software prior to secure system operations.Type: GrantFiled: January 10, 2017Date of Patent: January 8, 2019Assignee: Intel CorporationInventors: James A. Sutton, II, David W. Grawrock
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Patent number: 10042649Abstract: A method and apparatus for initiating secure operations in a microprocessor system is described. In one embodiment, one initiating logical processor initiates the process by halting the execution of the other logical processors, and then loading initialization and secure virtual machine monitor software into memory. The initiating processor then loads the initialization software into secure memory for authentication and execution. The initialization software then authenticates and registers the secure virtual machine monitor software prior to secure system operations.Type: GrantFiled: January 10, 2017Date of Patent: August 7, 2018Assignee: Intel CorporationInventors: James A. Sutton, II, David W. Grawrock
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Patent number: 10031759Abstract: A method and apparatus for initiating secure operations in a microprocessor system is described. In one embodiment, one initiating logical processor initiates the process by halting the execution of the other logical processors, and then loading initialization and secure virtual machine monitor software into memory. The initiating processor then loads the initialization software into secure memory for authentication and execution. The initialization software then authenticates and registers the secure virtual machine monitor software prior to secure system operations.Type: GrantFiled: September 24, 2015Date of Patent: July 24, 2018Assignee: Intel CorporationInventors: James A Sutton, David W Grawrock