Abstract: In various embodiments, a cell culture medium, or a nucleoside cocktail transmission (NCT) medium for the culture of stem cells with improved genetic stability, cellular function and regeneration ability is provided. Illustrative culture media comprise a basal culture medium for stem cells, where the culture medium is supplemented with one or more nucleoside triphosphates (e.g., dNTPs and/or NPs) or one or more precursors thereof. Illustrative NCT media comprise a delivery vehicle (e g. skin creams or other vehicle) containing one or more nucleoside triphosphates (e.g., dNTPs and/or NPs) or one or more precursors thereof. The NCT medium provides, inter alia, direct delivery of nucleoside cocktails into human tissues (such as skin) for regenerative, cosmetic and/or therapeutic purposes.

Abstract: Disclosed herein are three types of skin-derived cells. One type of the cells is mesenchymal stem cells characterized by expression of the cell surface biomarker cluster of differentiation (CD) 146, the second type expresses CD271. The third type of cells is regeneration-associated cells characterized by expression of the cell surface biomarkers stage-specific embryonic antigen 3 (SSEA3) and CD 105 (clone 35). Also disclosed are methods of isolating, purifying, culturing, storing, and using these cells.

Abstract: A substantially pure population of human somatic cells that have enhanced potential to become induced pluripotent stem cells (iPS cells) is provided. Also provided are methods for generating this population of cells and methods for generating iPS cells from this population of cells.

Abstract: Cell compositions for tissue engineering are provided which contain a population of autologous, minimally passaged dermal fibroblasts in combination with a tissue engineering matrix or scaffold, or material forming a matrix or scaffold. In one embodiment, the population of fibroblasts is genetically engineered to secrete a therapeutic protein in an amount effective to induce tissue growth or tissue repair when the cell composition is transplanted into a subject in need thereof. For example, the therapeutic protein can be a bone morphogenic protein when the tissue to be treated is bone tissue. A preferred bone morphogenic protein is BMP-2.

Abstract: A communications system may include a plurality of electronic devices having respective different device types and each configured to wirelessly communicate via a plurality of different wireless communications formats. The system may also include a mobile wireless communications device including a plurality of application modules associated with respective electronic device types and configured to communicate via a first one of the wireless communications formats.

Abstract: A mobile communications device may include a near field communication (NFC) transceiver switchable between a plurality of modes including a first NFC mode and a second NFC mode, wherein the second NFC mode has a lower power consumption level associated therewith than the first NFC mode. The mobile communications device may further include a processor coupled with the NFC transceiver and capable of activating an application, switching the NFC transceiver to operate in the first NFC mode in response to activating the application, and switching the NFC transceiver to the second NFC mode based upon a failure to establish NFC communications within a threshold time of switching the NFC transceiver to the first NFC mode.

Abstract: A mobile communications device may include a near field communication (NFC) transceiver switchable between a plurality of modes including a first NFC mode and a second NFC mode, wherein the second NFC mode has a lower power consumption level associated therewith than the first NFC mode. The mobile communications may further include a processor coupled with the NFC transceiver and capable of activating an application, switching the NFC transceiver to operate in the first NFC mode in response to activating the application, and switching the NFC transceiver to the second NFC mode based upon a failure to establish NFC communications within a threshold time of switching the NFC transceiver to the first NFC mode.

Abstract: A communications system may include a plurality of electronic devices having respective different device types and each configured to wirelessly communicate via a plurality of different wireless communications formats. The system may also include a mobile wireless communications device including a plurality of application modules associated with respective electronic device types and configured to communicate via a first one of the wireless communications formats.

Abstract: A substantially pure population of human somatic cells that have enhanced potential to become induced pluripotent stem cells (iPS cells) is provided. Also provided are methods for generating this population of cells and methods for generating iPS cells from this population of cells.

Abstract: A communications system may include a plurality of electronic devices having respective different device types and each configured to wirelessly communicate via a plurality of different wireless communications formats. The system may also include a mobile wireless communications device including a plurality of application modules associated with respective electronic device types and configured to communicate via a first one of the wireless communications formats.

Abstract: A delivery system for local drug delivery to a target site of internal body tissue is provided. The delivery system comprises a source electrode adapted to be positioned proximate to a target site of internal body tissue. A counter electrode is in electrical communication with the source electrode, and is configured to cooperate with the source electrode to form a localized electric field proximate to the target site. A reservoir is configured to be disposed such that the reservoir is capable of interacting with the localized electric field. The reservoir is configured to carry a cargo capable of being delivered to the target site when exposed to the localized electric field. Associated methods are also provided.

Abstract: There is disclosed an improved poppy straw of a stably reproducing Papaver somniferum for the extraction of thebaine and/or oripavine, the threshed straw having thebaine and oripavine constituting about 50% by weight or greater of the alkaloid combination consisting of morphine, codeine, thebaine and oripavine.

Abstract: Purified totipotent stem cells and pluripotent stems cells derived by somatic cell nuclear transfer are disclosed herein, as well as cell lines, multipotent cells and differentiated cells produced from these stem cells. The stem cells are produced from an enucleated host cell from a first donor and nuclear genetic material from a somatic cell of a second donor. Methods for making and using such compositions of such stem cells are also provided.

Abstract: Purified totipotent stem cells and pluripotent stems cells derived by somatic cell nuclear transfer are disclosed herein, as well as cell lines, multipotent cells and differentiated cells produced from these stem cells. The stem cells are produced from an enucleated host cell from a first donor and nuclear genetic material from a somatic cell of a second donor. Methods for making and using such compositions of such stem cells are also provided.

Abstract: A filter material for removing toxins and/or environmental contaminants from a body of gas, comprising bentonite disposed within a support arranged so as to allow contact between the body of gas and the bentonite.

Abstract: Purified totipotent stem cells and pluripotent stems cells derived by somatic cell nuclear transfer are disclosed herein, as well as cell lines, multipotent cells and differentiated cells produced from these stem cells. The stem cells are produced from an enucleated host cell from a first donor and nuclear genetic material from a somatic cell of a second donor. Methods for making and using such compositions of such stem cells are also provided.

Abstract: A fin locking mechanism for locking in place, and subsequently unlocking fins for installation on a missile having a plurality of otherwise moveable fins. Where the fins are mounted to a crank arm, there is a locking detent, with a locking notch, integral to the crank arm. A spring loaded locking plunger has an end which fits into the locking notch. The locking plungers are mounted into the assembly housing locking plunger channels. A base plate is spaced from the locking detent such that when one end of the locking plunger is fitted into the locking notch, the other end of the locking plunger is slidably pressed against the base plate by the spring loading, and the locking plunger is relatively perpendicular to the base plate. The base plate also has a plurality of locking plunger recesses, wherein when one end of the locking plunger resides in the locking plunger recesses, the other end of the locking plunger will not reach the locking notch and therefore the fins will be unlocked.

Abstract: A locking device for a disc retaining hub includes a base and a head that lock together over the hub to lock a disc on the hub until a portion of the locking device is destroyed. The head or the base of the locking device includes locking fingers that allow the head and base to lock together in a one-way snap fit connection. The locking mechanism may also cooperate with the disc retaining hub to lock itself to the hub. The locking mechanism prevents the disc from being removed from the hub until the locking mechanism is destroyed by the user.

Abstract: A hand-held container for paint and painting implements is provided. The body of the paint container includes an internal reservoir for holding paint and a magnet housed within the body for securing a paint brush or the like within the reservoir. An automatically adjusting, flexible handle that includes a living hinges provides a means for holding a person's hand against the exterior of the body. The paint container also includes a body that is dividable into multiple compartments. A textured surface covers a portion of exterior of the handle and the body and creates a non-slip surface useful for gripping the container. A portion of the container is shaped in a manner that allows the container to function as a pitcher for dispensing fluids such as paint. Stabilizing legs formed on or attached to the front portion of the container allow the container to be also be used as a paint tray.

Abstract: A delivery device for a medicament including: a housing, a receptacle holding a medicament in the form of a power; and a source of propellant, wherein the housing provides an inlet and an outlet for the receptacle, wherein the inlet is in fluid communication with the source of propellant and is directed against the medicament and the outlet is spaced from the medicament to allow aerosolization of the medicament; the device provides improved delivery efficiency, particularly a delivered fine particle fraction of greater than 20% by weight.