Patents by Inventor James C. Sturm

James C. Sturm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ON-CHIP MICROFLUIDIC PROCESSING OF PARTICLES
    Publication number: 20230280261
    Abstract: Described herein are microfluidic devices and methods that can greatly improve cell quality, streamline workflows, and lower costs. Applications include research and clinical diagnostics in cancer, infectious disease, and inflammatory disease, among other disease areas.
    Type: Application
    Filed: September 26, 2022
    Publication date: September 7, 2023
    Inventors: Michael GRISHAM, Curt I. CIVIN, James C. STURM, Robert H. AUSTIN, Joseph D'SILVA, Yu CHEN
  • METHODS AND DEVICES FOR HIGH THROUGHPUT PURIFICATION
    Publication number: 20230266211
    Abstract: Described herein are devices and methods for high throughput purification of particles. In some cases, methods and devices described herein can be used to remove erythrocytes and purify leukocytes and raise the quality of umbilical cord blood and other transplant grafts, thereby significantly improving patient outcomes.
    Type: Application
    Filed: September 20, 2022
    Publication date: August 24, 2023
    Inventors: Joseph D'SILVA, Robert H. AUSTIN, Curt CIVIN, James C. STURM
  • DETERMINISTIC LATERAL DISPLACEMENT ARRAY WITH A SINGLE COLUMN OF BUMPING OBSTACLES
    Publication number: 20230146950
    Abstract: Provided are microfluidic sorting devices comprising: a sample inlet, a single column comprising a plurality of bumping features configured for lateral displacement situated in a microfluidic channel, and a plurality of outlets, wherein the single column creates a main channel and a secondary channel in the microfluidic channel, wherein the sample inlet, the plurality of outlets, and the main channel and secondary channel are in fluid connection.
    Type: Application
    Filed: April 1, 2021
    Publication date: May 11, 2023
    Inventors: Weibin LIANG, James C. STURM
  • On-chip microfluidic processing of particles
    Patent number: 11493428
    Abstract: Described herein are microfluidic devices and methods that can greatly improve cell quality, streamline workflows, and lower costs. Applications include research and clinical diagnostics in cancer, infectious disease, and inflammatory disease, among other disease areas.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: November 8, 2022
    Assignees: GPB SCIENTIFIC, INC., UNIVERSITY OF MARYLAND, BALTIMORE, THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Michael Grisham, Curt I Civin, James C. Sturm, Robert H. Austin, Joseph D'Silva, Yu Chen
  • Methods and devices for high throughput purification
    Patent number: 11486802
    Abstract: Described herein are devices and methods for high throughput purification of particles. In some cases, methods and devices described herein can be used to remove erythrocytes and purify leukocytes and raise the quality of umbilical cord blood and other transplant grafts, thereby significantly improving patient outcomes.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: November 1, 2022
    Assignees: UNIVERSITY OF MARYLAND, BALTIMORE, THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Joseph D'Silva, Robert H. Austin, Curt Civin, James C. Sturm
  • Methods for preparing therapeutically active cells using microfluidics
    Patent number: 11306288
    Abstract: The present invention is directed to the use of microfluidics in the preparation of cells and compositions for therapeutic uses.
    Type: Grant
    Filed: March 4, 2021
    Date of Patent: April 19, 2022
    Assignees: GPB SCIENTIFIC, INC., UNIVERSITY OF MARYLAND, BALTIMORE, THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Anthony Ward, Roberto Campos-Gonzalez, Alison Skelley, Khushroo Gandhi, Curt Civin, James C. Sturm, Michael Grisham
  • Methods for Preparing Therapeutically Active Cells Using Microfluidics
    Publication number: 20220041985
    Abstract: The present invention is directed to the use of microfluidics in the preparation of cells and compositions for therapeutic uses.
    Type: Application
    Filed: September 6, 2021
    Publication date: February 10, 2022
    Applicants: GPB SCIENTIFIC, INC., UNIVERSITY OF MARYLAND, BALTIMORE, THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Anthony WARD, Roberto CAMPOS-GONZALEZ, Alison SKELLEY, Khushroo GANDHI, Curt CIVIN, James C. STURM, Michael GRISHAM
  • HIGH EFFICIENCY MICROFLUIDIC PURIFICATION OF STEM CELLS TO IMPROVE TRANSPLANTS
    Publication number: 20210395682
    Abstract: Described herein is a novel, highly efficient system to remove erythrocytes and purify leukocytes would raise the quality of UCB and other transplant grafts, thereby significantly improving patient outcomes.
    Type: Application
    Filed: September 1, 2021
    Publication date: December 23, 2021
    Applicants: UNIVERSITY OF MARYLAND, BALTIMORE, THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Curt I. CIVIN, James C. STURM, Robert H. AUSTIN
  • Methods for preparing therapeutically active cells using microfluidics
    Patent number: 11149251
    Abstract: The present invention is directed to the use of microfluidics in the preparation of cells and compositions for therapeutic uses.
    Type: Grant
    Filed: September 2, 2020
    Date of Patent: October 19, 2021
    Assignees: GPB Scientific, Inc., The Trustees of Princeton University, University of Maryland, Baltimore
    Inventors: Anthony Ward, Roberto Campos-Gonzalez, Alison Skelley, Khushroo Gandhi, Curt Civin, James C. Sturm, Michael Grisham
  • High efficiency microfluidic purification of stem cells to improve transplants
    Patent number: 11142746
    Abstract: Described herein is a novel, highly efficient system to remove erythrocytes and purify leukocytes would raise the quality of UCB and other transplant grafts, thereby significantly improving patient outcomes.
    Type: Grant
    Filed: November 16, 2015
    Date of Patent: October 12, 2021
    Assignees: University of Maryland, Baltimore, The Trustees of Princeton University
    Inventors: Curt I. Civin, James C. Sturm, Robert H. Austin
  • MICROFLUIDIC METHODS FOR THE PREPARATION OF CELLS
    Publication number: 20210290675
    Abstract: The present invention is directed to the use of microfluidics in the preparation of genetically transformed cells and compositions for therapeutic uses.
    Type: Application
    Filed: July 11, 2019
    Publication date: September 23, 2021
    Applicants: GPB SCIENTIFIC, INC., THE TRUSTEES OF PRINCETON UNIVERSITY, UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Anthony WARD, Roberto CAMPOS-GONZALEZ, Alison SKELLEY, Khushroo GANDHI, Michael GRISHAM, Curt CIVIN, James C. STURM
  • Methods for Preparing Therapeutically Active Cells Using Microfluidics
    Publication number: 20210207094
    Abstract: The present invention is directed to the use of microfluidics in the preparation of cells and compositions for therapeutic uses.
    Type: Application
    Filed: March 4, 2021
    Publication date: July 8, 2021
    Applicants: GPB SCIENTIFIC, INC., UNIVERSITY OF MARYLAND, BALTIMORE, THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Anthony WARD, Roberto CAMPOS-GONZALEZ, Alison SKELLEY, Khushroo GANDHI, Curt CIVIN, James C. STURM, Michael GRISHAM
  • METHODS AND DEVICES FOR MULTI-STEP CELL PURIFICATION AND CONCENTRATION
    Publication number: 20210156787
    Abstract: Described herein are microfluidic devices and methods that can separate and concentrate particles in a sample.
    Type: Application
    Filed: February 4, 2021
    Publication date: May 27, 2021
    Applicants: GPB SCIENTIFIC, INC., UNIVERSITY OF MARYLAND, BALTIMORE, THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Anthony WARD, Khushroo GANDHI, Alison SKELLEY, Curt CIVIN, James C. STURM, Lee AURICH, Michael GRISHAM, Joseph D'SILVA, Robert H. Austin
  • Methods for preparing therapeutically active cells using microfluidics
    Patent number: 10988734
    Abstract: The present invention is directed to the use of microfluidics in the preparation of cells and compositions for therapeutic uses.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: April 27, 2021
    Assignees: GPB Scientific, Inc., The Trustees of Princeton University, University of Maryland, Baltimore
    Inventors: Anthony Ward, Roberto Campos-Gonzalez, Alison Skelley, Khushroo Gandhi, Curt Civin, James C. Sturm, Michael Grisham
  • Methods and devices for multi-step cell purification and concentration
    Patent number: 10976232
    Abstract: Described herein are microfluidic devices and methods that can separate and concentrate particles in a sample.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: April 13, 2021
    Assignees: GPB Scientific, Inc., The Trustees of Princeton University, University of Maryland, Baltimore
    Inventors: Anthony Ward, Khushroo Gandhi, Alison Skelley, Curt Civin, James C. Sturm, Lee Aurich, Michael Grisham, Joseph D'Silva, Robert H. Austin
  • Methods for Preparing Therapeutically Active Cells Using Microfluidics
    Publication number: 20200399600
    Abstract: The present invention is directed to the use of microfluidics in the preparation of cells and compositions for therapeutic uses.
    Type: Application
    Filed: September 2, 2020
    Publication date: December 24, 2020
    Applicants: GPB SCIENTIFIC, INC., UNIVERSITY OF MARYLAND, BALTIMORE, THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Anthony WARD, Roberto CAMPOS-GONZALEZ, Alison SKELLEY, Khushroo GANDHI, Curt CIVIN, James C. STURM, Michael GRISHAM
  • Methods and devices for high throughput purification
    Patent number: 10852220
    Abstract: Described herein are devices and methods for high throughput purification of particles. In some cases, methods and devices described herein can be used to remove erythrocytes and purify leukocytes and raise the quality of umbilical cord blood and other transplant grafts, thereby significantly improving patient outcomes.
    Type: Grant
    Filed: September 30, 2019
    Date of Patent: December 1, 2020
    Assignees: The Trustees of Princeton University, University of Maryland, Baltimore
    Inventors: Joseph D'Silva, Robert H. Austin, Curt Civin, James C. Sturm
  • Methods for preparing therapeutically active cells using microfluidics
    Patent number: 10844353
    Abstract: The present invention is directed to the use of microfluidics in the preparation of cells and compositions for therapeutic uses.
    Type: Grant
    Filed: August 22, 2018
    Date of Patent: November 24, 2020
    Assignees: GPB Scientific, Inc., The Trustees of Princeton University, University of Maryland, Baltimore
    Inventors: Anthony Ward, Roberto Campos-Gonzalez, Alison Skelley, Khushroo Gandhi, Curt Civin, James C. Sturm, Michael Grisham
  • Methods for Preparing Therapeutically Active Cells Using Microfluidics
    Publication number: 20200056153
    Abstract: The present invention is directed to the use of microfluidics in the preparation of cells and compositions for therapeutic uses.
    Type: Application
    Filed: October 24, 2019
    Publication date: February 20, 2020
    Applicants: GPB SCIENTIFIC, LLC, UNIVERSITY OF MARYLAND, BALTIMORE, THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Anthony WARD, Roberto CAMPOS-GONZALEZ, Alison SKELLEY, Khushroo GANDHI, Curt CIVIN, James C. STURM, Michael GRISHAM
  • METHODS AND DEVICES FOR HIGH THROUGHPUT PURIFICATION
    Publication number: 20200025657
    Abstract: Described herein are devices and methods for high throughput purification of particles. In some cases, methods and devices described herein can be used to remove erythrocytes and purify leukocytes and raise the quality of umbilical cord blood and other transplant grafts, thereby significantly improving patient outcomes.
    Type: Application
    Filed: September 30, 2019
    Publication date: January 23, 2020
    Applicants: UNIVERSITY OF MARYLAND, BALTIMORE, THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Joseph D'SILVA, Robert H. AUSTIN, Curt CIVIN, James C. STURM