Patents by Inventor James C. Sturm

James C. Sturm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200025669
    Abstract: Described herein are microfluidic devices and methods that can separate and concentrate particles in a sample.
    Type: Application
    Filed: September 30, 2019
    Publication date: January 23, 2020
    Applicants: GPB SCIENTIFIC, LLC, UNIVERSITY OF MARYLAND, BALTIMORE, THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Anthony WARD, Khushroo GANDHI, Alison SKELLEY, Curt CIVIN, James C. STURM, Lee AURICH, Michael GRISHAM, Joseph D'SILVA, Roberto CAMPOS-GONZALEZ, Robert H. Austin
  • Publication number: 20200025657
    Abstract: Described herein are devices and methods for high throughput purification of particles. In some cases, methods and devices described herein can be used to remove erythrocytes and purify leukocytes and raise the quality of umbilical cord blood and other transplant grafts, thereby significantly improving patient outcomes.
    Type: Application
    Filed: September 30, 2019
    Publication date: January 23, 2020
    Applicants: UNIVERSITY OF MARYLAND, BALTIMORE, THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Joseph D'SILVA, Robert H. AUSTIN, Curt CIVIN, James C. STURM
  • Publication number: 20190366342
    Abstract: The present invention is directed to the use of Deterministic Lateral Displacement in the preparation of cells and compositions for therapeutic uses.
    Type: Application
    Filed: October 23, 2017
    Publication date: December 5, 2019
    Applicants: GPB SCIENTIFIC, LLC, UNIVERSITY OF MARYLAND, BALTIMORE, THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Anthony WARD, Roberto CAMPOS-GONZALEZ, Alison SKELLEY, Khushroo GANDHI, Michael GRISHAM, Curt CIVIN, James C. STURM
  • Patent number: 10324011
    Abstract: Described herein are devices and methods for high throughput purification of particles. In some cases, methods and devices described herein can be used to remove erythrocytes and purify leukocytes and raise the quality of umbilical cord blood and other transplant grafts, thereby significantly improving patient outcomes.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: June 18, 2019
    Assignees: The Trustees of Princeton University, University of Maryland, Baltimore
    Inventors: Joseph D'Silva, Robert H. Austin, James C. Sturm, Curt I. Civin
  • Publication number: 20190137369
    Abstract: Described herein are devices and methods for high throughput purification of particles. In some cases, methods and devices described herein can be used to remove erythrocytes and purify leukocytes and raise the quality of umbilical cord blood and other transplant grafts, thereby significantly improving patient outcomes.
    Type: Application
    Filed: September 6, 2018
    Publication date: May 9, 2019
    Applicants: UNIVERSITY OF MARYLAND, BALTIMORE, THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Joseph D'SILVA, Robert H. AUSTIN, Yu CHEN, Curt CIVIN, James C. STURM
  • Publication number: 20190071639
    Abstract: The present invention is directed to the use of microfluidics in the preparation of cells and compositions for therapeutic uses.
    Type: Application
    Filed: August 22, 2018
    Publication date: March 7, 2019
    Applicants: GPB SCIENTIFIC, LLC, UNIVERSITY OF MARYLAND, BALTIMORE, THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Anthony WARD, Roberto CAMPOS-GONZALEZ, Alison SKELLEY, Khushroo GANDHI, Curt CIVIN, James C. STURM, Michael GRISHAM
  • Patent number: 10013108
    Abstract: A three dimensional touch sensing system having a touch surface configured to detect a touch input located above the touch surface is disclosed. The system includes a plurality of capacitive touch sensing electrodes disposed on the touch surface, each electrode having a baseline capacitance and a touch capacitance based on the touch input. An oscillating plane is disposed below the touch surface. A touch detector is configured to drive one of the touch sensing electrodes with an AC signal having a frequency that shifts from a baseline frequency to a touch frequency based on the change in electrode capacitance from the baseline capacitance to the touch capacitance. The touch detector is configured to drive the oscillating plane to the touch frequency.
    Type: Grant
    Filed: July 7, 2017
    Date of Patent: July 3, 2018
    Assignee: THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Yingzhe Hu, Liechao Huang, Naveen Verma, Sigurd Wagner, James C. Sturm
  • Publication number: 20180046313
    Abstract: A three dimensional touch sensing system having a touch surface configured to detect a touch input located above the touch surface is disclosed. The system includes a plurality of capacitive touch sensing electrodes disposed on the touch surface, each electrode having a baseline capacitance and a touch capacitance based on the touch input. An oscillating plane is disposed below the touch surface. A touch detector is configured to drive one of the touch sensing electrodes with an AC signal having a frequency that shifts from a baseline frequency to a touch frequency based on the change in electrode capacitance from the baseline capacitance to the touch capacitance. The touch detector is configured to drive the oscillating plane to the touch frequency.
    Type: Application
    Filed: July 7, 2017
    Publication date: February 15, 2018
    Applicant: The Trustees of Princeton University
    Inventors: Yingzhe Hu, Liechao Huang, Naveen Verma, Sigurd Wagner, James C. Sturm
  • Publication number: 20170333900
    Abstract: Described herein are microfluidic devices and methods that can greatly improve cell quality, streamline workflows, and lower costs. Applications include research and clinical diagnostics in cancer, infectious disease, and inflammatory disease, among other disease areas.
    Type: Application
    Filed: April 4, 2017
    Publication date: November 23, 2017
    Inventors: Michael Grisham, Curt I. Civin, James C. Sturm, Robert H. Austin
  • Publication number: 20170248508
    Abstract: Described herein are microfluidic devices and methods that can separate and concentrate particles in a sample.
    Type: Application
    Filed: May 15, 2017
    Publication date: August 31, 2017
    Inventors: Anthony WARD, Khushroo GANDHI, Alison SKELLEY, Curt CIVIN, James C. STURM, Lee AURICH, Michael GRISHAM, Joseph D'SILVA, Roberto CAMPOS-GONZALEZ, Robert H. Austin
  • Patent number: 9740353
    Abstract: A three dimensional touch sensing system having a touch surface configured to detect a touch input located above the touch surface is disclosed. The system includes a plurality of capacitive touch sensing electrodes disposed on the touch surface, each electrode having a baseline capacitance and a touch capacitance based on the touch input. An oscillating plane is disposed below the touch surface. A touch detector is configured to drive one of the touch sensing electrodes with an AC signal having a frequency that shifts from a baseline frequency to a touch frequency based on the change in electrode capacitance from the baseline capacitance to the touch capacitance. The touch detector is configured to drive the oscillating plane to the touch frequency.
    Type: Grant
    Filed: November 4, 2015
    Date of Patent: August 22, 2017
    Assignee: THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Yingzhe Hu, Liechao Huang, Naveen Verma, Sigurd Wagner, James C. Sturm
  • Publication number: 20170209864
    Abstract: Described herein are improved microfluidic devices and methods for processing cells that can improve cell quality, streamline workflows, and lower costs. Applications include research and clinical diagnostics in cancer, infectious disease, and inflammatory disease, among other disease areas.
    Type: Application
    Filed: August 3, 2015
    Publication date: July 27, 2017
    Inventors: Michael GRISHAM, Curt I. CIVIN, James C. STURM, Robert H. AUSTIN, Joseph D'SILVA, Yu CHEN
  • Publication number: 20170123528
    Abstract: A three dimensional touch sensing system having a touch surface configured to detect a touch input located above the touch surface is disclosed. The system includes a plurality of capacitive touch sensing electrodes disposed on the touch surface, each electrode having a baseline capacitance and a touch capacitance based on the touch input. An oscillating plane is disposed below the touch surface. A touch detector is configured to drive one of the touch sensing electrodes with an AC signal having a frequency that shifts from a baseline frequency to a touch frequency based on the change in electrode capacitance from the baseline capacitance to the touch capacitance. The touch detector is configured to drive the oscillating plane to the touch frequency.
    Type: Application
    Filed: November 4, 2015
    Publication date: May 4, 2017
    Inventors: Yingzhe Hu, Liechao Huang, Naveen Verma, Sigurd Wagner, James C. Sturm
  • Publication number: 20160247043
    Abstract: Large-area electronics (LAE) enables the formation of a large number of sensors capable of spanning dimensions on the order of square meters. An example is X-ray imagers, which have been scaling both in dimension and number of sensors, today reaching millions of pixels. However, processing of the sensor data requires interfacing thousands of signals to CMOS ICs, because the implementation of complex functions in LAE has proven unviable due to the low electrical performance and inherent variability of the active devices available, namely amorphous silicon (a-Si) thin-film transistors (TFTs) on glass. Envisioning applications that perform sensing on even greater scales, disclosed is an approach whereby high-quality image detection is performed directly in the LAE domain using TFTs. The high variability and number of process defects affecting both the TFTs and sensors are overcome using a machine-learning algorithm, known as Error-Adaptive Classifier Boosting (EACB), to form an embedded classifier.
    Type: Application
    Filed: February 19, 2016
    Publication date: August 25, 2016
    Inventors: Warren Rieutort-Louis, Tiffany Moy, Zhuo Wang, Naveen Verma, Sigurd Wagner, James C. Sturm
  • Publication number: 20160168539
    Abstract: Described herein is a novel, highly efficient system to remove erythrocytes and purify leukocytes would raise the quality of UCB and other transplant grafts, thereby significantly improving patient outcomes.
    Type: Application
    Filed: November 16, 2015
    Publication date: June 16, 2016
    Inventors: Curt I. CIVIN, James C. STURM, Robert H. AUSTIN
  • Publication number: 20160139012
    Abstract: Described herein are devices and methods for high throughput purification of particles. In some cases, methods and devices described herein can be used to remove erythrocytes and purify leukocytes and raise the quality of umbilical cord blood and other transplant grafts, thereby significantly improving patient outcomes.
    Type: Application
    Filed: March 14, 2014
    Publication date: May 19, 2016
    Applicants: THE TRUSTEES OF PRINCETON UNIVERSITY, UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Joseph D'SILVA, Robert H. AUSTIN, James C. STURM, Yu CHEN, Curt I. CIVIN
  • Publication number: 20160047735
    Abstract: A microfluidic device comprises: a channel extending from a plurality of inlets to a plurality of outlets, wherein the channel is bounded by a first wall and a second wall opposite from the first wall; and an array of obstacles disposed within the channel configured to deflect particles in a sample comprising the particles toward the second wall when the particles are flowed from the inlets to the outlets. The particles are inputted into at least one of the plurality of inlets and are deflected through a series of parallel flow streams flowing from the plurality of inlets to the plurality of outlets while being deflected toward the second wall, wherein streams in the parallel flows comprise a reagent. Microfluidic devices and methods greatly improve cell quality, streamline workflows, and lower costs. Applications include research and clinical diagnostics in cancer, infectious disease, and inflammatory disease, among other disease areas.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 18, 2016
    Inventors: Michael GRISHAM, Curt I. CIVIN, James C. STURM, Robert H. AUSTIN, Joseph D'SILVA, Yu CHEN
  • Publication number: 20150064153
    Abstract: Described herein is a novel, highly efficient system to remove erythrocytes and purify leukocytes would raise the quality of UCB and other transplant grafts, thereby significantly improving patient outcomes.
    Type: Application
    Filed: March 14, 2014
    Publication date: March 5, 2015
    Applicants: THE TRUSTEES OF PRINCETON UNIVERSITY, UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Curt I. Civin, James C. Sturm, Robert H. Austin
  • Publication number: 20150034159
    Abstract: A hole-blocking silicon/titanium-oxide heterojunction for silicon photovoltaic devices and methods of forming are disclosed. The electronic device includes at least two electrodes having a current path between the two electrodes. The electronic device also includes a heterojunction formed of a titanium-oxide layer deposited over a Si layer and being disposed in the current path. The heterojunction is configured to function as a hole blocker. The first electrode may be electrically coupled to the Si layer and a second electrode may be electrically coupled to the titanium-oxide layer. The device may also include a PN junction disposed in the Si layer, in the current path. The device may also include an electron-blocking heterojunction on silicon in the current path.
    Type: Application
    Filed: March 14, 2013
    Publication date: February 5, 2015
    Applicant: The Trustees of Princeton University
    Inventors: Sushobhan Avasthi, James C. Sturm, William E. McClain, Jeffrey Schwartz
  • Publication number: 20140342375
    Abstract: Described herein are microfluidic devices and methods that can greatly improve cell quality, streamline workflows, and lower costs. Applications include research and clinical diagnostics in cancer, infectious disease, and inflammatory disease, among other disease areas.
    Type: Application
    Filed: March 14, 2014
    Publication date: November 20, 2014
    Applicants: UNIVERSITY OF MARYLAND, GPB SCIENTIFIC, LLC, THE TRUSTEES OF PRINCETON UNIVERSITY
    Inventors: Michael Grisham, Curt I. Civin, James C. Sturm, Robert H. Austin