Patents by Inventor James Callaway

James Callaway has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNOGLOBULIN FORMULATION AND METHOD OF PREPARATION THEREOF
    Publication number: 20210292419
    Abstract: A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
    Type: Application
    Filed: March 3, 2021
    Publication date: September 23, 2021
    Inventors: David J. Burke, Shaun E. Buckley, Sherwood Russ Lehrman, Barbara Horsey O'Connor, James Callaway, Christopher P. Phillips
  • Immunoglobulin formulation and method of preparation thereof
    Patent number: 10954303
    Abstract: A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: March 23, 2021
    Assignee: BIOGEN MA INC.
    Inventors: David J. Burke, Shaun E. Buckley, Sherwood Russ Lehrman, Barbara Horsey O'Connor, James Callaway, Christopher P. Phillips
  • IMMUNOGLOBULIN FORMULATION AND METHOD OF PREPARATION THEREOF
    Publication number: 20180194843
    Abstract: A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
    Type: Application
    Filed: March 7, 2018
    Publication date: July 12, 2018
    Inventors: David J. Burke, Shaun E. Buckley, Sherwood Russ Lehrman, Barbara Horsey O'Connor, James Callaway, Christopher P. Phillips
  • Immunotherapy regimes dependent on ApoE status
    Patent number: 9644025
    Abstract: The invention provides methods of immunotherapy of Alzheimer's and similar diseases in which the regime administered to a patient depends on the ApoE genotype of the patient.
    Type: Grant
    Filed: October 17, 2008
    Date of Patent: May 9, 2017
    Assignees: WYETH LLC, JANSSEN SCIENCES IRELAND UC
    Inventors: Ronald Black, Lars Ekman, Ivan Lieberburg, Michael Grundman, James Callaway, Keith M. Gregg, Jack Steven Jacobsen, Davinder Gill, Lioudmila Tchistiakova, Angela Widom
  • Use of tau to monitor immunotherapy
    Patent number: 9272030
    Abstract: The invention provides methods of immunotherapy of Alzheimer's and similar diseases in which the regime administered is monitored by measuring levels of tau.
    Type: Grant
    Filed: April 22, 2011
    Date of Patent: March 1, 2016
    Assignees: JANSSEN SCIENCES IRELAND UC, WYETH LLC
    Inventors: Ronald Black, Jack Steven Jacobsen, Lioudmila Tchistiakova, Angela Widom, Davinder Gill, Lars Ekman, Ivan Lieberburg, Michael Grundman, James Callaway, Keith M. Gregg, Wagner Zago, Manuel J. Buttini, Gene G. Kinney
  • USE OF TAU TO MONITOR IMMUNOTHERAPY
    Publication number: 20150118223
    Abstract: The invention provides methods of immunotherapy of Alzheimer's and similar diseases in which the regime administered is monitored by measuring levels of tau.
    Type: Application
    Filed: April 22, 2011
    Publication date: April 30, 2015
    Applicants: WYETH LLC, JANSSEN ALZHEIMER IMMUNOTHERAPY
    Inventors: Ronald Black, Jack Steven Jacobsen, Lioudmila Tchistiakova, Angela Widom, Davinder Gill, Lars Ekman, Ivan Lieberburg, Michael Grundman, James Callaway, Keith M. Gregg, Wagner Zago, Manuel J. Buttini, Gene G. Kinney
  • PEGYLATED C-PEPTIDE
    Publication number: 20150087586
    Abstract: The present invention relates to modified forms of C-peptide, and methods for their use. In one aspect, the modified forms of C-peptide comprise conjugated C-peptide derivatives which exhibit superior pharmacokinetic and biological activity in vivo.
    Type: Application
    Filed: March 25, 2013
    Publication date: March 26, 2015
    Inventors: Sheri Barrack, James Callaway, Michelle Mazzoni
  • Method of treating a diabetic subject having a microvascular impairment disorder by a pegylated C-peptide
    Patent number: 8962553
    Abstract: The present invention relates to PEGylated C-peptide derivatives comprising at least one PEG group attached to the N-terminus, which exhibit improved pharmacokinetic and biological activity in vivo.
    Type: Grant
    Filed: November 19, 2012
    Date of Patent: February 24, 2015
    Assignee: Cebix AB
    Inventors: John Wahren, Sheri Barrack, James Callaway, Michelle Mazzoni, Howard Foyt, Mark Daniels
  • IMMUNOGLOBULIN FORMULATION AND METHOD OF PREPARATION THEREOF
    Publication number: 20150044206
    Abstract: A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
    Type: Application
    Filed: October 27, 2014
    Publication date: February 12, 2015
    Applicant: BIOGEN IDEC MA INC.
    Inventors: David J. BURKE, Shaun E. BUCKLEY, Sherwood Russ LEHRMAN, Barbara Horsey O'CONNOR, James CALLAWAY, Christopher P. PHILLIPS
  • Pegylated C-peptide
    Patent number: 8927488
    Abstract: The present invention relates to modified forms of C-peptide, and methods for their use. In one aspect, the modified forms of C-peptide comprise PEGylated C-peptide derivatives comprising at least one PEG group attached to the N-terminus, which exhibit superior pharmacokinetic and biological activity in vivo.
    Type: Grant
    Filed: May 17, 2011
    Date of Patent: January 6, 2015
    Assignee: Cebix, Inc.
    Inventors: Sheri Barrack, James Callaway, Michelle Mazzoni
  • Immunoglobulin formulation and method of preparation thereof
    Patent number: 8900577
    Abstract: A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
    Type: Grant
    Filed: September 6, 2012
    Date of Patent: December 2, 2014
    Assignee: Biogen Idec Ma Inc.
    Inventors: David J. Burke, Shaun E. Buckley, Sherwood Russ Lehrman, Barbara Horsey O'Connor, James Callaway, Christopher P. Phillips
  • Method for treating multiple sclerosis and crohn's disease
    Patent number: 8815236
    Abstract: A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
    Type: Grant
    Filed: November 14, 2012
    Date of Patent: August 26, 2014
    Assignee: Biogen Idec MA Inc.
    Inventors: David J. Burke, Shaun E. Buckley, Sherwood Russ Lehrman, Barbara Horsey O'Connor, James Callaway, Christopher P. Phillips
  • Treatment of amyloidogenic diseases
    Patent number: 8784810
    Abstract: The invention provides preferred dosage ranges, maximum concentrations, average concentrations and monitoring regimes for use in treatment of Alzheimer's disease using antibodies to A?. The invention also provides monitoring regimes that as can assess changes in symptoms or signs of the patient following treatment.
    Type: Grant
    Filed: October 17, 2008
    Date of Patent: July 22, 2014
    Assignees: Janssen Alzheimer Immunotherapy, Wyeth LLC
    Inventors: Ivan Lieberburg, James Callaway, Michael Grundman
  • Pegylated C-peptide
    Patent number: 8691755
    Abstract: The present invention relates to modified forms of C-peptide, and methods for their use. In one aspect, the modified forms of C-peptide comprise PEGylated C-peptide derivatives comprising at least one PEG group attached to the N-terminus, which exhibit superior pharmacokinetic and biological activity in vivo.
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: April 8, 2014
    Assignee: Cebix AB
    Inventors: Sheri Barrack, James Callaway, Michelle Mazzoni
  • METHODS AND KITS FOR PREVENTING HYPOGLYCEMIA
    Publication number: 20130345124
    Abstract: Improved methods and kits for treating the long-term complications of diabetes that reduce the risk of the patient developing hypoglycemia during C-peptide therapy. The use of such methods and kits can also maintain good glycemic control and avoid excessive weight gain that may otherwise be associated with excessive insulin administration or caloric intake during C-peptide therapy.
    Type: Application
    Filed: March 1, 2013
    Publication date: December 26, 2013
    Applicant: Cebix AB
    Inventors: John Wahren, Karin Ekberg, James Callaway
  • Treatment of amyloidogenic diseases
    Patent number: 8613920
    Abstract: The invention provides preferred dosage ranges, maximum concentrations, average concentrations and monitoring regimes for use in treatment of Alzheimer's disease using antibodies to A?. The invention also provides monitoring regimes that can assess changes in symptoms or signs of the patient following treatment.
    Type: Grant
    Filed: July 27, 2007
    Date of Patent: December 24, 2013
    Assignees: Janssen Alzheimer Immunotherapy, Wyeth LLC
    Inventors: Ivan Lieberburg, James Callaway, Michael Grundman
  • USE OF TAU TO MONITOR IMMUNOTHERAPY
    Publication number: 20130209453
    Abstract: The invention provides methods of immunotherapy of Alzheimer's and similar diseases in which the regime administered is monitored by measuring levels of tau.
    Type: Application
    Filed: April 22, 2011
    Publication date: August 15, 2013
    Applicants: WYETH LLC, JANSSEN ALZHEIMER IMMUNOTHERAPY
    Inventors: Ronald Black, Jack Steven Jacobsen, Lioudmila Tchistiakova, Angela Widom, Davinder Gill, Lars Ekman, Ivan Lieberburg, Michael Grundman, James Callaway, Keith M. Gregg, Wagner Zago, Manuel J. Buttini
  • Methods and kits for preventing hypoglycemia
    Patent number: 8410049
    Abstract: Improved methods and kits for treating the long-term complication of diabetes that reduce the risk of the patient developing hypoglycemia during C-peptide therapy. The use of such methods and kits, can also maintain good glycemic control, and avoid excessive weight gain that may otherwise be associated with excessive insulin administration or caloric intake during C-peptide therapy.
    Type: Grant
    Filed: March 4, 2010
    Date of Patent: April 2, 2013
    Assignee: Cebix
    Inventors: John Wahren, Karin Ekberg, James Callaway
  • Immunoglobulin formulation and method of preparation thereof
    Patent number: 8349321
    Abstract: A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
    Type: Grant
    Filed: October 2, 2009
    Date of Patent: January 8, 2013
    Assignee: Elan Pharmaceuticals, Inc.
    Inventors: David J. Burke, Shaun E. Buckley, Sherwood Russ Lehrman, Barbara Horsey O'Connor, James Callaway, Christopher P. Phillips
  • Immunoglobulin Formulation and Method of Preparation Thereof
    Publication number: 20120328614
    Abstract: A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
    Type: Application
    Filed: September 6, 2012
    Publication date: December 27, 2012
    Applicant: Elan Pharmaceuticals, Inc.
    Inventors: David J. Burke, Shaun E. Buckley, Sherwood Russ Lehrman, Barbara Horsey O'Connor, James Callaway, Christopher P. Phillips