Patents by Inventor James Clayton

James Clayton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220175264
    Abstract: An MR Spectroscopy (MRS) system and approach is provided for diagnosing painful and non-painful discs in chronic, severe low back pain patients (DDD-MRS). A DDD-MRS pulse sequence generates and acquires DDD-MRS spectra within intervertebral disc nuclei for later signal processing and diagnostic analysis. An interfacing DDD-MRS signal processor receives output signals of the DDD-MRS spectra acquired and is configured to optimize signal-to-noise ratio by an automated system that selectively conducts optimal channel selection, phase and frequency correction, and frame editing as appropriate for a given acquisition series. A diagnostic processor calculates a diagnostic value for the disc based upon a weighted factor set of criteria that uses MRS data extracted from the acquired and processed MRS spectra for multiple chemicals that have been correlated to painful vs. non-painful discs. A display provides an indication of results for analyzed discs as an overlay onto a MRI image of the lumbar spine.
    Type: Application
    Filed: November 16, 2021
    Publication date: June 9, 2022
    Inventors: James Clayton Peacock, III, John Patrick Claude, Paul Henry Kane
  • Publication number: 20220181292
    Abstract: A polymerizable composition includes at least one monomer, a photoinitiator capable of initiating polymerization of the monomer when exposed to light, and a phosphor capable of producing light when exposed to radiation (typically X-rays). The material is particularly suitable for bonding components at ambient temperature in situations where the bond joint is not accessible to an external light source. An associated method includes: placing a polymerizable adhesive composition, including a photoinitiator and energy converting material, such as a down-converting phosphor, in contact with at least two components to be bonded to form an assembly; and, irradiating the assembly with radiation at a first wavelength, capable of conversion (down-conversion by the phosphor) to a second wavelength capable of activating the photoinitiator, to prepare items such as inkjet cartridges, wafer-to-wafer assemblies, semiconductors, integrated circuits, and the like.
    Type: Application
    Filed: January 6, 2022
    Publication date: June 9, 2022
    Applicant: IMMUNOLIGHT, LLC
    Inventors: Zakaryae FATHI, James CLAYTON, Harold WALDER, Frederic A. BOURKE, JR.
  • Patent number: 11348755
    Abstract: Presented systems and methods facilitate efficient and effective generation and delivery of radiation. A radiation generation system can comprise: a particle beam gun, a high energy dissipation anode target (HEDAT); and a liquid anode control component. In some embodiments, the particle beam gun generates an electron beam. The HEDAT includes a solid anode portion (HEDAT-SAP) and a liquid anode portion (HEDAT-LAP) that are configured to receive the electron beam, absorb energy from the electron beam, generate a radiation beam, and dissipate heat. The radiation beam can include photons that can have radiation characteristics (e.g., X-ray wavelength, ionizing capability, etc.). The liquid anode control component can control a liquid anode flow to the HEDAT. The HEDAT-SAP and HEDAT-LAP can cooperatively operate in radiation generation and their configuration can be selected based upon contribution of respective HEDAT-SAP and the HEDAT-LAP characteristics to radiation generation.
    Type: Grant
    Filed: October 1, 2020
    Date of Patent: May 31, 2022
    Assignee: Varian Medical Systems, Inc.
    Inventors: Josh Star-Lack, James Clayton
  • Patent number: 11270973
    Abstract: A polymerizable composition includes at least one monomer, a photoinitiator capable of initiating polymerization of the monomer when exposed to light, and a phosphor capable of producing light when exposed to radiation (typically X-rays). The material is particularly suitable for bonding components at ambient temperature in situations where the bond joint is not accessible to an external light source. An associated method includes: placing a polymerizable adhesive composition, including a photoinitiator and energy converting material, such as a down-converting phosphor, in contact with at least two components to be bonded to form an assembly; and, irradiating the assembly with radiation at a first wavelength, capable of conversion (down-conversion by the phosphor) to a second wavelength capable of activating the photoinitiator, to prepare items such as inkjet cartridges, wafer-to-wafer assemblies, semiconductors, integrated circuits, and the like.
    Type: Grant
    Filed: August 17, 2020
    Date of Patent: March 8, 2022
    Assignee: Immunolight, LLC
    Inventors: Zakaryae Fathi, James Clayton, Harold Walder, Frederic A. Bourke, Jr.
  • Patent number: 11246793
    Abstract: A manual ear pump including one or more of a support element configured to releasably engage an external ear canal and having an interior chamber, a resilient element capable of being resiliently deformed coupled to a support element, and an aperture disposed on a support element bottom surface communicating with the external ear canal and interior chamber.
    Type: Grant
    Filed: August 23, 2019
    Date of Patent: February 15, 2022
    Assignee: NOCIRA, LLC
    Inventors: David Mager George, James Clayton Peacock, III
  • Patent number: 11179057
    Abstract: Systems and methods are provided for processing a set of multiple serially acquired magnetic resonance spectroscopy (MRS) free induction decay (FID) frames from a multi-frame MRS acquisition series from a region of interest (ROI) in a subject, and for providing a post-processed MRS spectrum. Processing parameters are dynamically varied while measuring results to determine the optimal post-processed results. Spectral regions opposite water from chemical regions of interest are evaluated and used in at least one processing operation. Frequency shift error is estimated via spectral correlation between free induction decay (FID) frames and a reference spectrum. Multiple groups of FID frames within the acquired set are identified to different phases corresponding with a phase step cycle of the acquisition. Baseline correction is also performed via rank order filter (ROF) estimate and a polynomial fit.
    Type: Grant
    Filed: May 7, 2020
    Date of Patent: November 23, 2021
    Assignee: NociMed, Inc.
    Inventors: James Clayton Peacock, III, John Patrick Claude, Paul Henry Kane, Ricardo Dario Pradenas
  • Publication number: 20210274949
    Abstract: A display vase adapted to bold a variety of longitudinal stems or sticks, the vase, including a retainer mountable within the transparent vase that can hold a multitude of display items. The retainer may sit on a shelf or retaining ring, inside the vase. The retainer may include an array of hexagonally shaped cells that may interlock with a lower level of interlocking cells.. Also included is a method of arranging and displaying stemmed items in a vase. A retainer is set in a vase and stems are secured therethrough, preferably into a frog apparatus at bottom of vase.
    Type: Application
    Filed: March 8, 2021
    Publication date: September 9, 2021
    Applicant: Woods IP Holdings LLC
    Inventors: Elise WOODS, James Clayton WEEMS
  • Publication number: 20210220674
    Abstract: Systems and methods provide radiotherapy treatment by focusing an electron beam on an x-ray target (e.g., a tungsten plate) to produce a high-yield x-ray output with improved field shaping. A modified electron beam spatial distribution is employed to scan the x-ray target, such as a 2D periodic beam path, which advantageously lowers the x-ray target temperature compared to the typical compact beam spatial distribution. As a result, the x-ray target can produce a high yield output without sacrificing the x-ray target life span. The use of a 2D periodic beam path allows a much colder x-ray target functioning regime such that more dosage can be applied in a short period of time compared to existing techniques.
    Type: Application
    Filed: April 9, 2021
    Publication date: July 22, 2021
    Inventors: Anuj PURWAR, Dragos CONSTANTIN, James CLAYTON
  • Patent number: 11007381
    Abstract: Systems and methods provide radiotherapy treatment by focusing an electron beam on an x-ray target (e.g., a tungsten plate) to produce a high-yield x-ray output with improved field shaping. A modified electron beam spatial distribution is employed to scan the x-ray target, such as a 2D periodic beam path, which advantageously lowers the x-ray target temperature compared to the typical compact beam spatial distribution. As a result, the x-ray target can produce a high yield output without sacrificing the x-ray target life span. The use of a 2D periodic beam path allows a much colder x-ray target functioning regime such that more dosage can be applied in a short period of time compared to existing techniques.
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: May 18, 2021
    Assignee: Varian Medical Systems, Inc
    Inventors: Anuj Purwar, Dragos Constantin, James Clayton
  • Publication number: 20210128368
    Abstract: Absorbent articles with biodegradable and/or biocompostable elements are disclosed, wherein the absorbent articles include sensors. The sensors detect and determine variables associated with collected fluids, solids, and gases, including a presence of fluids, solids, and gases, a volume of fluids, solids, and gases, and/or a distribution of fluids, solids, and gases. In one embodiment, the sensors and/or connected computing systems are calibrated to capacities and other properties of elements within the articles, including superabsorbent polymers, and are operable to trigger an alert based on detected or determined conditions.
    Type: Application
    Filed: October 2, 2020
    Publication date: May 6, 2021
    Applicant: Tethis, Inc.
    Inventors: Ryan Nicholas Chan, Gordon Sidney Cox, Vladimiro Nettel, James Clayton Robinson, Robin Weitkamp
  • Publication number: 20210052185
    Abstract: Systems and methods are provided for processing a set of multiple serially acquired magnetic resonance spectroscopy (MRS) free induction decay (FID) frames from a multi-frame MRS acquisition series from a region of interest (ROI) in a subject, and for providing a post-processed MRS spectrum. Processing parameters are dynamically varied while measuring results to determine the optimal post-processed results. Spectral regions opposite water from chemical regions of interest are evaluated and used in at least one processing operation. Frequency shift error is estimated via spectral correlation between free induction decay (FID) frames and a reference spectrum. Multiple groups of FID frames within the acquired set are identified to different phases corresponding with a phase step cycle of the acquisition. Baseline correction is also performed via rank order filter (ROF) estimate and a polynomial fit.
    Type: Application
    Filed: May 7, 2020
    Publication date: February 25, 2021
    Inventors: James Clayton Peacock, III, John Patrick Claude, Paul Henry Kane, Ricardo Dario Pradenas
  • Publication number: 20210035946
    Abstract: A polymerizable composition includes at least one monomer, a photoinitiator capable of initiating polymerization of the monomer when exposed to light, and a phosphor capable of producing light when exposed to radiation (typically X-rays). The material is particularly suitable for bonding components at ambient temperature in situations where the bond joint is not accessible to an external light source. An associated method includes: placing a polymerizable adhesive composition, including a photoinitiator and energy converting material, such as a down-converting phosphor, in contact with at least two components to be bonded to form an assembly; and, irradiating the assembly with radiation at a first wavelength, capable of conversion (down-conversion by the phosphor) to a second wavelength capable of activating the photoinitiator, to prepare items such as inkjet cartridges, wafer-to-wafer assemblies, semiconductors, integrated circuits, and the like.
    Type: Application
    Filed: August 17, 2020
    Publication date: February 4, 2021
    Applicant: Immunolight, LLC
    Inventors: Zakaryae FATHI, James CLAYTON, Harold WALDER, Frederic A. BOURKE, JR.
  • Patent number: 10910188
    Abstract: Presented systems and methods facilitate efficient and effective generation and delivery of radiation. A radiation generation system can comprise: a particle beam gun, a high energy dissipation anode target (HEDAT); and a liquid anode control component. In some embodiments, the particle beam gun generates an electron beam. The HEDAT includes a solid anode portion (HEDAT-SAP) and a liquid anode portion (HEDAT-LAP) that are configured to receive the electron beam, absorb energy from the electron beam, generate a radiation beam, and dissipate heat. The radiation beam can include photons that can have radiation characteristics (e.g., X-ray wavelength, ionizing capability, etc.). The liquid anode control component can control a liquid anode flow to the HEDAT. The HEDAT-SAP and HEDAT-LAP can cooperatively operate in radiation generation and their configuration can be selected based upon contribution of respective HEDAT-SAP and the HEDAT-LAP characteristics to radiation generation.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: February 2, 2021
    Assignee: Varian Medical Systems, Inc.
    Inventors: Josh Star-Lack, James Clayton
  • Publication number: 20210027973
    Abstract: Presented systems and methods facilitate efficient and effective generation and delivery of radiation. A radiation generation system can comprise: a particle beam gun, a high energy dissipation anode target (HEDAT); and a liquid anode control component. In some embodiments, the particle beam gun generates an electron beam. The HEDAT includes a solid anode portion (HEDAT-SAP) and a liquid anode portion (HEDAT-LAP) that are configured to receive the electron beam, absorb energy from the electron beam, generate a radiation beam, and dissipate heat. The radiation beam can include photons that can have radiation characteristics (e.g., X-ray wavelength, ionizing capability, etc.). The liquid anode control component can control a liquid anode flow to the HEDAT. The HEDAT-SAP and HEDAT-LAP can cooperatively operate in radiation generation and their configuration can be selected based upon contribution of respective HEDAT-SAP and the HEDAT-LAP characteristics to radiation generation.
    Type: Application
    Filed: October 1, 2020
    Publication date: January 28, 2021
    Inventors: Josh Star-Lack, James Clayton
  • Publication number: 20200261284
    Abstract: A disposable undergarment is disclosed. The undergarment includes a chassis and an absorbent core assembly. The chassis includes a front section, a crotch section and a rear section and elastic threads in those sections. The absorbent core is located in the crotch section, with portions of it extending into the front and rear sections. The core assembly includes a first or upper section of including plural pockets of a free slow acting but high absorbency SAP, and a second or underlying second section including plural pockets of a free fast acting by lower absorbency SAP. The SAP of the upper and lower sections exhibits various characteristics to facilitate to effective and efficient absorption of a fluid insult into the core assembly.
    Type: Application
    Filed: May 4, 2020
    Publication date: August 20, 2020
    Inventors: Donald A. Sheldon, Joseph Howard, William Terenzoni, James Clayton Robinson
  • Patent number: 10748868
    Abstract: A polymerizable composition includes at least one monomer, a photoinitiator capable of initiating polymerization of the monomer when exposed to light, and a phosphor capable of producing light when exposed to radiation (typically X-rays). The material is particularly suitable for bonding components at ambient temperature in situations where the bond joint is not accessible to an external light source. An associated method includes: placing a polymerizable adhesive composition, including a photoinitiator and energy converting material, such as a down-converting phosphor, in contact with at least two components to be bonded to form an assembly; and, irradiating the assembly with radiation at a first wavelength, capable of conversion (down-conversion by the phosphor) to a second wavelength capable of activating the photoinitiator, to prepare items such as inkjet cartridges, wafer-to-wafer assemblies, semiconductors, integrated circuits, and the like.
    Type: Grant
    Filed: August 14, 2018
    Date of Patent: August 18, 2020
    Assignee: IMMUNOLIGHT, LLC
    Inventors: Zakaryae Fathi, James Clayton, Harold Walder, Frederic A. Bourke, Jr.
  • Publication number: 20200222272
    Abstract: A manual ear pump including one or more of a support element configured to releasably engage an external ear canal and having an interior chamber, a resilient element capable of being resiliently deformed coupled to a support element, and an aperture disposed on a support element bottom surface communicating with the external ear canal and interior chamber.
    Type: Application
    Filed: August 23, 2019
    Publication date: July 16, 2020
    Inventors: David Mager George, James Clayton Peacock, III
  • Publication number: 20200215611
    Abstract: A curable resin or adhesive composition includes at least one monomer, a photoinitiator capable of initiating polymerization of the monomer when exposed to light, and at least one energy converting material, preferably a phosphor, capable of producing light when exposed to radiation (typically X-rays). The material is particularly suitable for bonding components at ambient temperature in situations where the bond joint is not accessible to an external light source.
    Type: Application
    Filed: March 16, 2020
    Publication date: July 9, 2020
    Applicant: IMMUNOLIGHT, LLC.
    Inventors: Zakaryae FATHI, James CLAYTON, Harold WALDER, Frederic A. BOURKE, JR.
  • Patent number: 10646135
    Abstract: Systems and methods are provided for processing a set of multiple serially acquired magnetic resonance spectroscopy (MRS) free induction decay (FID) frames from a multi-frame MRS acquisition series from a region of interest (ROI) in a subject, and for providing a post-processed MRS spectrum. Processing parameters are dynamically varied while measuring results to determine the optimal post-processed results. Spectral regions opposite water from chemical regions of interest are evaluated and used in at least one processing operation. Frequency shift error is estimated via spectral correlation between free induction decay (FID) frames and a reference spectrum. Multiple groups of FID frames within the acquired set are identified to different phases corresponding with a phase step cycle of the acquisition. Baseline correction is also performed via rank order filter (ROF) estimate and a polynomial fit.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: May 12, 2020
    Assignee: NOCIMED, INC.
    Inventors: James Clayton Peacock, III, John Patrick Claude, Paul Henry Kane, Ricardo Dario Pradenas
  • Publication number: 20200100698
    Abstract: An MR Spectroscopy (MRS) system and approach is provided for diagnosing painful and non-painful discs in chronic, severe low back pain patients (DDD-MRS). A DDD-MRS pulse sequence generates and acquires DDD-MRS spectra within intervertebral disc nuclei for later signal processing and diagnostic analysis. An interfacing DDD-MRS signal processor receives output signals of the DDD-MRS spectra acquired and is configured to optimize signal-to-noise ratio by an automated system that selectively conducts optimal channel selection, phase and frequency correction, and frame editing as appropriate for a given acquisition series. A diagnostic processor calculates a diagnostic value for the disc based upon a weighted factor set of criteria that uses MRS data extracted from the acquired and processed MRS spectra for multiple chemicals that have been correlated to painful vs. non-painful discs. A display provides an indication of results for analyzed discs as an overlay onto a MRI image of the lumbar spine.
    Type: Application
    Filed: May 9, 2019
    Publication date: April 2, 2020
    Inventors: James Clayton Peacock, III, John Patrick Claude, Paul Henry Kane, Jeffrey C. Lotz