Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: Compliance with retail display regulations that retailers are subject to within a plurality of jurisdictions is managed. Retail display regulations may differ from jurisdiction to jurisdiction. To facilitate compliance, retail display regulations for a plurality of jurisdictions are centrally maintained. The regulations may then be used to dynamically generate retail display materials for locations across a plurality of jurisdictions with different regulatory schemes. The central storage and/or maintenance of the retail display regulations may facilitate compliance with disparate regulatory schemes that retailers are subject to based in part of retail location. Central storage of the retail display regulations may facilitate certification of compliance by regulating entities associated with the jurisdictions.

Abstract: Methods and systems for control and adjustment of the feed rate of mercury reemission control additives (MECA) to a wet flue gas desulfurization system. Predetermined sulfite concentration values are compared to actual sulfite concentrations measured in the scrubber liquid. The MECA feed to the recirculating scrubber liquor is then adjusted and regulated as a result of such comparisons.

Abstract: A trading platform for trading financial instruments, and in particular for generating pre-trade prices. In an exemplary embodiment, the trading platform includes computer software modules and provides graphical user interfaces to accept dealer bids and offers, aggregate the dealer positions, generate a pre-trade price, permit dealers to opt-in to a matching process (the sweep), and determine matches by comparing the positions and potential opposing positions. The trading systems and methods may generate a yield curve from the dealer bids and offers which may be used for the valuation of positions and collateral. The trading platform is also capable of matching orders and sending orders to be executed.

Abstract: Methods and systems for control and adjustment of the feed rate of mercury reemission control additives (MECA) to a wet flue gas desulfurization system. Predetermined sulfite concentration values are compared to actual sulfite concentrations measured in the scrubber liquid. The MECA feed to the recirculating scrubber liquor is then adjusted and regulated as a result of such comparisons.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: A method for establishing a corrosion protection system for an air cooled condenser is disclosed. The method includes receiving data associated with the physical properties and chemical process conditions of the air cooled condenser, utilizing a chemical process modeling component to simulate conditions of the air cooled condenser, and identifying an optimized corrosion protection system based on an evaluation of iteratively altered input variables.

Abstract: A water filter system for a CO2 sampling line positioned between a patient and a patient monitor to receive patient exhalation. The filter system includes at least one hydrophobic filter that adsorbs and prevents water from reaching the patient monitor. Alternatively, the filter system may include both a hydrophobic filter and a hydrophilic filter and optionally a desiccant.

Abstract: A method for forming a ceramic matrix composite article includes laying up a first group of plies; laying up a second group of plies, the first and second groups of plies being adjacent to each other; compacting the first group of plies and the second group of plies in the same processing step; and performing a first infiltration process on the first group of plies. The method also includes performing a second infiltration process on the second group of plies, the first infiltration process being one of a melt infiltration process or a chemical vapor infiltration process, and the second infiltration process being the other of the melt infiltration process or the chemical vapor infiltration process.

Abstract: Systems and methods are described for treating flue gas, for example from a coal fired power plant. The systems and methods include control of a wet flue gas desulfurization (WFGD) system to manage sulfite concentration in a slurry produced by the WFGD system. Oxygen is added to the slurry in an amount sufficient to produce a sulfite concentration in the slurry in the range of about 5 to 75 mg/L, an oxidation reduction potential in the range of about 100-250 mV, or both. The systems and methods also include the biological treatment to remove selenium from a liquid fraction of the slurry. The liquid fraction is treated in a biological reactor maintained under anoxic or anaerobic conditions to reduce its selenium concentration.

Abstract: A method for forming a ceramic matrix composite article includes laying up a first group of plies; laying up a second group of plies, the first and second groups of plies being adjacent to each other; compacting the first group of plies and the second group of plies in the same processing step; and performing a first infiltration process on the first group of plies. The method also includes performing a second infiltration process on the second group of plies, the first infiltration process being one of a melt infiltration process or a chemical vapor infiltration process, and the second infiltration process being the other of the melt infiltration process or the chemical vapor infiltration process.

Abstract: A ceramic matrix composite article includes a chemical vapor infiltration ceramic matrix composite base portion including ceramic fiber reinforcement material in a ceramic matrix material having between 0% and 5% free silicon. The ceramic matrix composite article further includes a melt infiltration ceramic matrix composite covering portion including a ceramic fiber reinforcement material in a ceramic matrix material having a greater percentage of free silicon than the chemical vapor infiltration ceramic matrix composite base portion.

Abstract: A coated component, along with method of forming the same, is provided. The coated component may include a substrate having a surface, a silicon-based bond coating on the surface of the substrate, and an EBC on the silicon-based bond coating. The silicon-based bond coating may include a silicon-phase contained within a refractory phase. The silicon-phase, when melted, is contained within the refractory phase and between the surface of the substrate and an inner surface of the environmental barrier coating. Such a coated component may be, in particular embodiments, a turbine component.

Abstract: A coated component, along with methods of its formation and use, is provided. The coated component may include a substrate having a surface, a first refractory layer on the surface of the substrate, a silicon-based bond coating on the first refractory, and an environmental barrier coating on the silicon-based bond coating. The silicon-based bond coating includes a silicon-phase contained within a refractory phase such that, when melted, the silicon-phase is contained within the refractory phase and between the surface of the substrate and an inner surface of the environmental barrier coating.

Abstract: A coated component, along with methods of its formation and use, is provided. The coated component may include a substrate having a surface with a plurality of cavities defined therein, a bond coating (e.g., including a silicon material) on the surface of the substrate within the cavities, and an environmental barrier coating over the surface of the substrate and encasing the bond coating within the cavities such that the bond coating, when melted, is contained within the cavities. Such a coated component may be, in one embodiment, a turbine component, such as a CMC component for use in a hot gas path of a gas turbine engine.

Abstract: Methods for forming a ceramic matrix composite (CMC) are generally provided. The method may include melt infiltrating a silicon mixture into a ceramic matrix composite preform, with the silicon mixture including SiGa, SiIn, or a mixture thereof. The silicon mixture may include silicon metal in combination with SiGa, SiIn, or the mixture thereof. Additionally, the silicon mixture may further include B within the SiGa, SiIn, or the mixture thereof (e.g., in the form of SiBGa, SiBIn, or a mixture thereof).

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: A ceramic matrix composite article includes a melt infiltration ceramic matrix composite substrate comprising a ceramic fiber reinforcement material in a ceramic matrix material having a first free silicon proportion, and a melt infiltration ceramic matrix composite outer layer comprising a ceramic fiber reinforcement material in a ceramic matrix material having a second free silicon proportion disposed on an outer surface of at least a portion of the substrate, or a polymer impregnation and pyrolysis ceramic matrix composite outer layer comprising a ceramic fiber reinforcement material in a ceramic matrix material having a second free silicon proportion disposed on an outer surface of at least a portion of the substrate. The second free silicon proportion is less than the first free silicon proportion.

Abstract: Methods for forming a ceramic matrix composite (CMC) are generally provided. The method may include melt infiltrating a silicon mixture into a ceramic matrix composite preform, with the silicon mixture including SiGa, SiIn, or a mixture thereof. The silicon mixture may include silicon metal in combination with SiGa, SiIn, or the mixture thereof. Additionally, the silicon mixture may further include B within the SiGa, SiIn, or the mixture thereof (e.g., in the form of SiBGa, SiBIn, or a mixture thereof).