Abstract: A vehicle with a load space to provide a chassis comprising a framework (10) comprising a pair of spaced-apart elongate longitudinal members (12, 14) connected by a pair of spaced-apart elongate lateral members (20, 22) and bracing for the thus-defined framework, a rear suspension attached to the rearmost lateral member (20) and comprising a trailing-arm arrangement (52), and a front suspension attached to the front most lateral member (22) and comprising a leading-arm arrangement (58). This creates a rigid core for the chassis, which also provides all four suspension mounting points.

Abstract: A kit for constructing a commercial vehicle supplied ex-works as a flat-pack package using the vehicle chassis as a pallet. The kit includes components comprising: a chassis, an engine attachable to the chassis, located within and supported by the chassis, and a plurality of upright chassis members attachable to the chassis thereby to define at least a cabin, placed flat over the chassis. The component making up the kit can be restrained in place, such as by wrapping or tying with suitable film, bands or cords. Body panels attachable to the chassis uprights can be supplied, placed flat over the chassis. Brake line, a wiring loom and major drivetrain items such as the engine, differential and propshaft may be pre-attached to the chassis in their final locations before shipping the kit. With suitable spacers, several such kits could be packed for transport in a single vehicle or container.

Abstract: An improved sample tube that includes a body portion having a longitudinal axis and a wall generally circumscribing the longitudinal axis. The body portion terminates in a distal tip having a dimple. The body portion includes at least one transparent portion (e.g., at the distal tip) that is adapted for transmitting light. The wail is configured for elastic deformation along at feast a portion of its length, including in a direction that is generally transverse to the longitudinal axis, so that it compressively and resiliently deforms and engages a wail defining an opening in a sample block of a PGR amplification instrument. The tube may be made by injection molding a polymeric material including a thermoplastic.

Abstract: A mounting device for a flat panel monitor. The mounting device comprises a front panel and a mating second rear panel for connection with one another to form a housing. At least the front panel has a plurality of mounting apertures therein for securing the housing to a desired flat panel monitor while the rear panel has a mounting mechanism which facilitates attachment of the housing to a desired support surface. An internal recess is formed between the front panel and the rear panel, when assembled with one another, and the internal recess is sized for accommodating and retaining at least one peripheral electronic device therein.

Abstract: An improved device and system for facilitating polymerase chain reaction including a light source, detector, waveguide, and filters that occupy minimal space and facilitate detection of stationary samples, reduced sample read time, and simultaneous reading of multiple light wavelengths.

Abstract: Current systems of distributing vehicles are inefficient, particularly in developing nations. To resolve this, we provide a kit for constructing a commercial vehicle supplied ex-works as a flat-pack package using the vehicle chassis as a pallet. Thus, the kit may include a chassis, an engine attachable to the chassis, located within and supported by the chassis, and a plurality of upright chassis members attachable to the chassis thereby to define at least a cabin, placed flat over the chassis. The elements making up the kit can be restrained in place, such as by wrapping or tying with suitable film, bands or cords. Body panels attachable to the chassis uprights can be supplied, placed flat over the chassis. Brake line, a wiring loom and major drivetrain items such as the engine, differential and propshaft may be pre-attached to the chassis in their final locations before shipping the kit. In this way, the complete kit can be prepared at a suitable factory and shipped as a “flat-pack” item.

Abstract: Described herein are systems and methods for providing simplified computing functionalities to a user. One embodiment provides a method for reporting on activity of a user of a simplified computing platform. The method includes making available at the simplified computing platform one or more normalised content items received from a data handling server. The data handling server is configured to receive data indicative of content items designated for display at the simplified computing platform, the data indicative of content items being received from a plurality of correspondents via a plurality of input channels. The server additionally normalises the content in accordance with a content normalisation protocol, and delivers the normalised content items for display at the simplified computing platform. An interface allows a user of the simplified computing platform make an interaction in respect of a given one of the content items.

Abstract: Described herein are systems and methods for providing simplified computing functionalities to a user. One embodiment provides a method including receiving, via one of a plurality of input channels, data indicative of content for display at a simplified computing platform. The data is processed thereby to identify an account holder to which the content is directed, and processed thereby to determine a primary content type. One or more content items of the primary content type from the data are extracted, and a signal defined for communication to a simplified computing platform associated with the identified account holder, thereby to instruct the simplified computing platform to make the one or more content items available for display via a software module configured specifically for the display of content of the primary content type.

Abstract: The present invention provides compounds of formula (I) useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf-mediated diseases.

Abstract: The invention is based on the discovery that compounds of Formula I are unexpectedly highly potent and selective inhibitors of the adenosine A1 receptor. Adenosine A1 antagonists can be useful in the prevention and/or treatment of numerous diseases, including cardiac and circulatory disorders, degenerative disorders of the central nervous system, respiratory disorders, and many diseases for which diuretic treatment is suitable.

Abstract: The invention is based on the discovery that compounds of Formula I are unexpectedly highly potent and selective inhibitors of the adenosine A1 receptor. Adenosine A1 antagonists can be useful in the prevention and/or treatment of numerous diseases, including cardiac and circulatory disorders, degenerative disorders of the central nervous system, respiratory disorders, and many diseases for which diuretic treatment is suitable.

Abstract: The invention is based on the discovery that compounds of formula (I) possess unexpectedly high affinity for the A2a adenosine receptor, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including Parkinson's disease.

Abstract: The invention is based on the discovery that compounds of Formula I are unexpectedly highly potent and selective inhibitors of the adenosine A1 receptor. Adenosine A1 antagonists can be useful in the prevention and/or treatment of numerous diseases, including cardiac and circulatory disorders, degenerative disorders of the central nervous system, respiratory disorders, and many diseases for which diuretic treatment is suitable.

Abstract: Systems and methods for the remote dispensing of packaged and non-packaged medical products using networked communications systems. A preferred embodiment of the invention utilizes a network to provide for the secure delivery of confidential patient information and the sending of dispense instructions to a remote dispensing station. A preferred embodiment of the present invention relates to systems and methods of dispensing samples of drugs or other medical products. Another preferred embodiment of the invention provides a system and method for dispensing non-prescription medications.

Abstract: The invention is based on the discovery that compounds of Formula I are unexpectedly highly potent and selective inhibitors of the adenosine A1 receptor. Adenosine A1 antagonists can be useful in the prevention and/or treatment of numerous diseases, including cardiac and circulatory disorders, degenerative disorders of the central nervous system, respiratory disorders, and many diseases for which diuretic treatment is suitable.

Abstract: The present invention relates to systems and methods for the remote dispensing of packaged and non-packaged medical products using networked communications systems. A preferred embodiment of the invention utilizes a network to provide for the secure delivery of confidential patient information and the sending of dispense instructions to a remote dispensing station. A preferred embodiment of the present invention relates to systems and methods of dispensing samples of drugs or other medical products. Another preferred embodiment of the invention provides a system and method for dispensing non-prescription medications.

Abstract: The present invention relates to systems and methods for the remote dispensing of packaged and non-packaged medical products using networked communications systems. A preferred embodiment of the invention utilizes a network to provide for the secure delivery of confidential patient information and the sending of dispense instructions to a remote dispensing station. A preferred embodiment of the present invention relates to systems and methods of dispensing samples of drugs or other medical products. Another preferred embodiment of the invention provides a system and method for dispensing non-prescription medications.

Abstract: The present invention relates to systems and methods for the remote dispensing of packaged and non-packaged medical products using networked communications systems. A preferred embodiment of the invention utilizes a network to provide for the secure delivery of confidential patient information and the sending of dispense instructions to a remote dispensing station. A preferred embodiment of the present invention relates to systems and methods of dispensing samples of drugs or other medical products. Another preferred embodiment of the invention provides a system and method for dispensing non-prescription medications.

Abstract: The present invention relates to systems and methods for the remote dispensing of packaged and non-packaged medical products using networked communications systems. A preferred embodiment of the invention utilizes a network to provide for the secure delivery of confidential patient information and the sending of dispense instructions to a remote dispensing station. A preferred embodiment of the present invention relates to systems and methods of dispensing samples of drugs or other medical products. Another preferred embodiment of the invention provides a system and method for dispensing non-prescription medications.