Patents by Inventor James Freeman

James Freeman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9988452
    Abstract: Antibody molecules that specifically bind to PD-L1 are disclosed. Combination therapies comprising the anti-PD-L1 antibody molecules are also disclosed. The anti-PD-L1 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious conditions and disorders.
    Type: Grant
    Filed: October 13, 2015
    Date of Patent: June 5, 2018
    Assignees: Novartis AG, DANA-FARBER CANCER INSTITUTE, INC., PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Gordon James Freeman, Arlene Helen Sharpe, Gerhard Johann Frey, Hwai Wen Chang, Jennifer Marie Mataraza, Glenn Dranoff
  • Publication number: 20180134121
    Abstract: A reinforcement assembly for a structural pillar includes an upper reinforcement that extends over a top of a wheel house and first and second surfaces. An area extends between the first and second surfaces such that the area defines a substantial right triangle over the wheel house. A slot within the area is defined to allow a duct connected to a casing to extend through the upper reinforcement. The reinforcement assembly further includes a lower reinforcement attached to the first surface of the upper reinforcement. The lower reinforcement extends parallel to the wheel house and perpendicular to the floor such that a load path is established through the upper and lower reinforcements.
    Type: Application
    Filed: November 15, 2016
    Publication date: May 17, 2018
    Inventors: Michael James FREEMAN, Richard Allen BODEY, Jr.
  • Patent number: 9884913
    Abstract: Antibody molecules that specifically bind to TIM-3 are disclosed. The anti-TIM-3 antibody molecules can be used to treat, prevent and/or diagnose immune, cancerous, or infectious conditions and/or disorders.
    Type: Grant
    Filed: March 17, 2017
    Date of Patent: February 6, 2018
    Assignees: Novartis AG, DANA-FARBER CANCER INSITITUTE, INC., Children's Medical Center Corporation
    Inventors: Catherine Anne Sabatos-Peyton, Barbara Brannetti, Alan S. Harris, Thomas Huber, Thomas Pietzonka, Jennifer Marie Mataraza, Walter A. Blattler, Daniel J. Hicklin, Maximiliano Vasquez, Rosemarie H. DeKruyff, Dale T. Umetsu, Gordon James Freeman, Tiancen Hu, John A. Taraszka, Fangmin Xu
  • Patent number: 9815898
    Abstract: Antibody molecules that specifically bind to PD-1 are disclosed. The anti-PD-1 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious conditions and disorders.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: November 14, 2017
    Assignees: Novartis AG, PRESIDENT AND FELLOWS OF HARVARD COLLEGE, DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Gordon James Freeman, Arlene Helen Sharpe, Walter A. Blattler, Jennifer Marie Mataraza, Catherine Anne Sabatos-Peyton, Hwai Wen Chang, Gerhard Johann Frey
  • Publication number: 20170247456
    Abstract: Antibody molecules that specifically bind to PD-1 are disclosed. The anti-PD-1 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious conditions and disorders.
    Type: Application
    Filed: May 15, 2017
    Publication date: August 31, 2017
    Applicants: Novartis AG, PRESIDENT AND FELLOWS OF HARVARD COLLEGE, DANA-FARBER CANCER INSTITUTE, INC., PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Gordon James Freeman, Arlene Helen Sharpe, Walter A. Blattler, Jennifer Marie Mataraza, Catherine Anne Sabatos-Peyton, Hwai Wen Chang, Gerhard Johann Frey
  • Publication number: 20170209962
    Abstract: An assembly and method of forming the assembly are disclosed. The assembly may include first and second components, the first component including a non-mating region and a mating region. The mating region may have an offset in a direction towards the second component and have a welding surface contacting the second component. A weld located within the welding surface may join the first and second components. The weld may be a laser weld. The method may include positioning a first component including a welding pad offset from a surrounding region of the first component such that the welding pad is in contact with a second component to form a gap between the surrounding region of the first component and the second component. The first component may then be welded to the second component in an area within the welding pad.
    Type: Application
    Filed: January 21, 2016
    Publication date: July 27, 2017
    Inventors: Jose de Jesus COLIN ESPINOZA, Michael James FREEMAN, Juergen Wilhelm HOVER, Guido H. MUELLER, Mario Alberto RUBIO MONROY
  • Patent number: 9713980
    Abstract: A vehicle is equipped with a spotlight. The spotlight has a rod that passes through a pillar of the vehicle, such as the A-pillar. The A-pillar includes one or more beams. The beam is provided with an aperture or a through-hole for the rod to pass through. One or more sleeves are provided with a tubular body and a flange. The flange is secured to the beam and is oriented such that the tubular body passes at least partially through the aperture or through-hole. The sleeve provides an engagement surface that surrounds the rod of the spotlight while improving structural rigidity of that portion of the pillar.
    Type: Grant
    Filed: November 17, 2015
    Date of Patent: July 25, 2017
    Assignee: Ford Global Technologies, LLC
    Inventors: Henry W. Hausler, Michael James Freeman
  • Publication number: 20170203795
    Abstract: A structural reinforcement assembly for a vehicle body structure is provided. The assembly may include a pillar portion, a roof cross member, and a bead formation. The pillar portion may disposed at a rear upper corner region of the body structure and between a rear quarter window opening and a liftgate opening defined by the body structure. The roof cross member may extend along an upper portion of the liftgate opening. The bead formation may extend from the pillar portion to the roof cross member to reinforce the rear upper corner region. The bead formation may define an arc shape having a first end located adjacent the roof cross member and an access hole.
    Type: Application
    Filed: January 14, 2016
    Publication date: July 20, 2017
    Inventors: Michael James Freeman, Mohammed F. Ahmed
  • Publication number: 20170198041
    Abstract: Antibody molecules that specifically bind to TIM-3 are disclosed. The anti-TIM-3 antibody molecules can be used to treat, prevent and/or diagnose immune, cancerous, or infectious conditions and/or disorders.
    Type: Application
    Filed: February 14, 2017
    Publication date: July 13, 2017
    Inventors: Catherine Anne Sabatos-Peyton, Barbara Brannetti, Alan S. Harris, Thomas Huber, Thomas Pietzonka, Jennifer Marie Mataraza, Walter A. Blattler, Daniel J. Hicklin, Maximiliano Vasquez, Rosemarie H. DeKruyff, Dale T. Umetsu, Gordon James Freeman, Tiancen Hu, John A. Taraszka, Fangmin Xu
  • Publication number: 20170190777
    Abstract: Antibody molecules that specifically bind to TIM-3 are disclosed. The anti-TIM-3 antibody molecules can be used to treat, prevent and/or diagnose immune, cancerous, or infectious conditions and/or disorders.
    Type: Application
    Filed: March 17, 2017
    Publication date: July 6, 2017
    Inventors: Catherine Anne Sabatos-Peyton, Barbara Brannetti, Alan S. Harris, Thomas Huber, Thomas Pietzonka, Jennifer Marie Mataraza, Walter A. Blattler, Daniel J. Hicklin, Maximiliano Vasquez, Rosemarie H. DeKruyff, Dale T. Umetsu, Gordon James Freeman, Tiancen Hu, John A. Taraszka, Fangmin Xu
  • Patent number: 9683048
    Abstract: Antibody molecules that specifically bind to PD-1 are disclosed. The anti-PD-1 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious conditions and disorders.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: June 20, 2017
    Assignees: NOVARTIS AG, DANA-FARBER CANCER INSTITUTE, INC., PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Gordon James Freeman, Arlene Helen Sharpe, Walter A. Blattler, Jennifer Marie Mataraza, Catherine Anne Sabatos-Peyton, Hwai Wen Chang, Gerhard Johann Frey
  • Publication number: 20170136941
    Abstract: A vehicle is equipped with a spotlight. The spotlight has a rod that passes through a pillar of the vehicle, such as the A-pillar. The A-pillar includes one or more beams. The beam is provided with an aperture or a through-hole for the rod to pass through. One or more sleeves are provided with a tubular body and a flange. The flange is secured to the beam and is oriented such that the tubular body passes at least partially through the aperture or through-hole. The sleeve provides an engagement surface that surrounds the rod of the spotlight while improving structural rigidity of that portion of the pillar.
    Type: Application
    Filed: November 17, 2015
    Publication date: May 18, 2017
    Inventors: Henry W. HAUSLER, Michael James FREEMAN
  • Patent number: 9605070
    Abstract: Antibody molecules that specifically bind to TIM-3 are disclosed. The anti-TIM-3 antibody molecules can be used to treat, prevent and/or diagnose immune, cancerous, or infectious conditions and/or disorders.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: March 28, 2017
    Assignees: Novartis AG, DANA-FARBER CANCER INSTITUTE, INC., Children's Medical Center Corporation
    Inventors: Catherine Anne Sabatos-Peyton, Barbara Brannetti, Alan S. Harris, Thomas Huber, Thomas Pietzonka, Jennifer Marie Mataraza, Walter A. Blattler, Daniel J. Hicklin, Maximiliano Vasquez, Rosemarie H. DeKruyff, Dale T. Umetsu, Gordon James Freeman, Tiancen Hu, John A. Taraszka, Fangmin Xu
  • Publication number: 20160108123
    Abstract: Antibody molecules that specifically bind to PD-L1 are disclosed. Combination therapies comprising the anti-PD-L1 antibody molecules are also disclosed. The anti-PD-L1 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious conditions and disorders.
    Type: Application
    Filed: October 13, 2015
    Publication date: April 21, 2016
    Inventors: Gordon James Freeman, Arlene Helen Sharpe, Gerhard Johann Frey, Hwai Wen Chang, Jennifer Marie Mataraza, Glenn Dranoff
  • Publication number: 20150218274
    Abstract: Antibody molecules that specifically bind to TIM-3 are disclosed. The anti-TIM-3 antibody molecules can be used to treat, prevent and/or diagnose immune, cancerous, or infectious conditions and/or disorders.
    Type: Application
    Filed: January 30, 2015
    Publication date: August 6, 2015
    Inventors: Catherine Anne Sabatos-Peyton, Barbara Brannetti, Alan S. Harris, Thomas Huber, Thomas Pietzonka, Jennifer Marie Mataraza, Walter A. Blattler, Daniel J. Hicklin, Maximiliano Vasquez, Rosemarie H. DeKruyff, Dale T. Umetsu, Gordon James Freeman, Tiancen Hu, John A. Taraszka, Fangmin Xu
  • Publication number: 20150210769
    Abstract: Antibody molecules that specifically bind to PD-1 are disclosed. The anti-PD-1 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious conditions and disorders.
    Type: Application
    Filed: January 23, 2015
    Publication date: July 30, 2015
    Inventors: Gordon James Freeman, Arlene Helen Sharpe, Walter A. Blattler, Jennifer Marie Mataraza, Catherine Anne Sabatos-Peyton, Hwai Wen Chang, Gerhard Johann Frey
  • Patent number: 8985471
    Abstract: The invention relates to a security tag made unique by randomly distributing a mixture of large numbers of multicolored small objects, such as two colored glass balls, into a regular geometric array or pattern onto a substrate and encapsulating those objects. The objects in the regular array on the substrate will create a unique, non-reproducible pattern. The data, saved to a secure database, can be processed and calculated quantities can be derived from the field of binary data, which can be affixed to the document or manufactured part that the stamp is affixed to. The regular array can be read out by scanner, quantities calculated, and compared to the values printed on the part or document. Additionally, the regular array can be read out by optical scanner and parts or all of the data compared to the data stored in the secure database.
    Type: Grant
    Filed: June 21, 2013
    Date of Patent: March 24, 2015
    Inventor: James Freeman
  • Patent number: 8919866
    Abstract: A side-support structure mounted over an upper side portion of a vehicle includes an upper horizontal portion attached to a portion of the roof of the vehicle. A central arcuate portion of the side-support structure is attached to a portion of the vehicle between the roof and the side-pillar of the vehicle. The side-support structure also includes a lower vertical portion attached to an upper portion of the side-pillar of the vehicle.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: December 30, 2014
    Assignee: Ford Global Technologies, LLC
    Inventors: Mike James Freeman, Gene A. Senn
  • Publication number: 20140265447
    Abstract: A side-support structure mounted over an upper side portion of a vehicle includes an upper horizontal portion attached to a portion of the roof of the vehicle. A central arcuate portion of the side-support structure is attached to a portion of the vehicle between the roof and the side-pillar of the vehicle. The side-support structure also includes a lower vertical portion attached to an upper portion of the side-pillar of the vehicle.
    Type: Application
    Filed: March 14, 2013
    Publication date: September 18, 2014
    Applicant: FORD GLOBAL TECHNOLOGIES, LLC
    Inventors: Mike James Freeman, Gene A Senn
  • Patent number: 8832708
    Abstract: Various embodiments enable a device to create a pool of at least one empty application. An empty application can be configured to contain resources that are common across one or more other applications and initialize the resources for the one or more other applications effective to reduce startup time of the other applications. In one or more embodiments, an empty application can further be populated with the one or more other applications effective to cause the one or more other applications to execute. Alternately or additionally, a device can be monitored for an idle state, and, upon determining the device is in the idle state, at least one empty application can be created.
    Type: Grant
    Filed: October 12, 2010
    Date of Patent: September 9, 2014
    Assignee: Microsoft Corporation
    Inventors: Bharath Siravara, Neil A. Brench, Arthur William James Freeman, Mark H. Krueger, David R. Anderson, Joerg Raymond Brown