Patents by Inventor James Guo
James Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240384325Abstract: Aspects of the present disclosure generally relate to methods and compositions for detecting an association between a RNA binding protein and a RNA. Some aspects of the present disclosure relate to methods of generating an antibody-bead conjugate pool. Some aspects of the present disclosure relate to kits and compositions for performing the methods disclosed herein.Type: ApplicationFiled: May 15, 2024Publication date: November 21, 2024Inventors: Erica Wolin, James Guo, Mitchell Guttman, Marko Jovanovic
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Patent number: 11851091Abstract: Embodiments for operational envelope detection (OED) with situational assessment are disclosed. In some embodiments, a method comprises: determining at least one current or future constraint for a trajectory of a vehicle in an environment that is associated with the vehicle becoming immobile for an extended period of time; determining a stopping-reason for immobility of the vehicle based on determining the at least one current or future constraint for the trajectory of the vehicle in the environment; identifying a timeout threshold based on the stopping-reason, wherein the timeout threshold is an amount of time a planning system of the vehicle will wait before initiating at least one remedial action to address the immobility; identifying that the timeout threshold is satisfied; and initiating the at least one remedial action for the vehicle based on the identifying that the timeout threshold is satisfied.Type: GrantFiled: September 14, 2021Date of Patent: December 26, 2023Assignee: Motional AD LLCInventors: Scott D. Pendleton, Zhiliang Chen, You Hong Eng, James Guo Ming Fu
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Patent number: 11845454Abstract: Embodiments for operational envelope detection (OED) with situational assessment are disclosed. Embodiments herein relate to an operational envelope detector that is configured to receive, as inputs, information related to sensors of the system and information related to operational design domain (ODD) requirements. The OED then compares the information related to sensors of the system to the information related to the ODD requirements, and identifies whether the system is operating within its ODD or whether a remedial action is appropriate to adjust the ODD requirements based on the current sensor information. Other embodiments are described and/or claimed.Type: GrantFiled: September 14, 2021Date of Patent: December 19, 2023Assignee: Motional AD LLCInventors: You Hong Eng, James Guo Ming Fu, Scott D. Pendleton, Yu Pan
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Publication number: 20230159026Abstract: Provided are methods for predicting motion of hypothetical agents, which can include receiving sensor data, generating a segmentation mask indicative of at least one occluded area, generating at least one hypothetical agent trajectory, determining at least one agent generation point, determining whether a threshold distance from the at least one agent generation point to the vehicle is satisfied, generating at least one agent, planning a path of the vehicle and controlling the vehicle according to the planned path. Systems and computer program products are also provided.Type: ApplicationFiled: November 19, 2021Publication date: May 25, 2023Inventors: Yu Pan, You Hong Eng, Scott D. Pendleton, James Guo Ming Fu
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Publication number: 20230093601Abstract: Embodiments for operational envelope detection (OED) with situational assessment are disclosed. Embodiments herein relate to an operational envelope detector that is configured to receive, as inputs, information related to sensors of the system and information related to operational design domain (ODD) requirements. The OED then compares the information related to sensors of the system to the information related to the ODD requirements, and identifies whether the system is operating within its ODD or whether a remedial action is appropriate to adjust the ODD requirements based on the current sensor information. Other embodiments are described and/or claimed.Type: ApplicationFiled: September 14, 2021Publication date: March 23, 2023Inventors: Scott D. Pendleton, Yu Pan, You Hong Eng, James Guo Ming Fu
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Publication number: 20230091987Abstract: Embodiments for operational envelope detection (OED) with situational assessment are disclosed. Embodiments herein relate to an operational envelope detector that is configured to receive, as inputs, information related to sensors of the system and information related to operational design domain (ODD) requirements. The OED then compares the information related to sensors of the system to the information related to the ODD requirements, and identifies whether the system is operating within its ODD or whether a remedial action is appropriate to adjust the ODD requirements based on the current sensor information. Other embodiments are described and/or claimed.Type: ApplicationFiled: September 14, 2021Publication date: March 23, 2023Inventors: Scott D. Pendleton, Zhiliang Chen, You Hong Eng, James Guo Ming Fu
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Publication number: 20230081111Abstract: Embodiments for operational envelope detection (OED) with situational assessment are disclosed. Embodiments herein relate to an operational envelope detector that is configured to receive, as inputs, information related to sensors of the system and information related to operational design domain (ODD) requirements. The OED then compares the information related to sensors of the system to the information related to the ODD requirements, and identifies whether the system is operating within its ODD or whether a remedial action is appropriate to adjust the ODD requirements based on the current sensor information. Other embodiments are described and/or claimed.Type: ApplicationFiled: September 14, 2021Publication date: March 16, 2023Inventors: You Hong Eng, James Guo Ming Fu, Scott D. Pendleton, Yu Pan
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Publication number: 20230077863Abstract: Provided are methods for search algorithms and safety verification for compliant domain volumes. The present techniques include identifying a parameterized scenario space and objective function. A boundary between compliant scenarios and non-compliant scenarios for metrics in the parameterized scenario space is determined. A total boundary of a domain volume corresponding to the parameterized scenario space is identified based on the boundaries between the compliant scenarios and non-compliant scenarios for each metric in the parameterized scenario space.Type: ApplicationFiled: September 9, 2022Publication date: March 16, 2023Inventors: Scott D. Pendleton, Aleksandar Petrov Petrov, Carter Tung Yung Fang, Minh Khang Pham, James Guo Ming Fu, You Hong Eng
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Publication number: 20230078779Abstract: Embodiments for operational envelope detection (OED) with situational assessment are disclosed. Embodiments herein relate to an operational envelope detector that is configured to receive, as inputs, information related to sensors of the system and information related to operational design domain (ODD) requirements. The OED then compares the information related to sensors of the system to the information related to the ODD requirements, and identifies whether the system is operating within its ODD or whether a remedial action is appropriate to adjust the ODD requirements based on the current sensor information. Other embodiments are described and/or claimed.Type: ApplicationFiled: September 14, 2021Publication date: March 16, 2023Inventors: You Hong Eng, James Guo Ming Fu, Scott D. Pendleton, Yu Pan
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Publication number: 20230039935Abstract: Provided are methods for scalable and realistic camera blockage dataset generation, which can include generating synthetic images depicting a blockage on or near an imaging sensor. The synthetic images may be created by combining one or more chroma key-extracted partial blockage image with one or more background images, the combination of which can provide a scalable blockage dataset. Metadata for each synthetic image can be generated along with the synthetic image, by annotating the portion of the synthetic image represented by the chroma key-extracted partial blockage image as constituting blockage. The synthetic images can be used to increase the accuracy of machine learning models trained to identify blockage by increasing the volume of data available for such training.Type: ApplicationFiled: August 1, 2022Publication date: February 9, 2023Inventors: Pan Yu, You Hong Eng, James Guo Ming Fu, Jiong Yang
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Patent number: 11400958Abstract: Provided are methods for learning to identify safety-critical scenarios for autonomous vehicles. First state information representing a first state of a driving scenario is received. The information includes a state of a vehicle and a state of an agent in the vehicle's environment. The first state information is processed with a neural network to determine at least one action to be performed by the agent, including a perception degradation action causing misperception of the agent by a perception system of the vehicle. Second state information representing a second state of the driving scenario is received after performance of the at least one action. A reward for the action is determined. First and second distances between the vehicle and the agent are determined and compared to determine the reward for the at least one action. At least one weight of the neural network is adjusted based on the reward.Type: GrantFiled: September 20, 2021Date of Patent: August 2, 2022Assignee: Motional AD LLCInventors: James Guo Ming Fu, Scott D. Pendleton, You Hong Eng, Yu Pan, Jiong Yang
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Patent number: 11221281Abstract: Provided is a heat treatment device for slide specimen testing, and the heat treatment device mainly includes a container, a base, a heater, a liquid outlet, a liquid inlet, a controller and a thermocouple. When such device is used together with devices such as a slide cover plate and a slide rack, a large amount of slide specimens can be carried out steps of reagent loading, cleaning, heat treatment, temperature maintaining and drying inside one same device, especially multi-step operations such as an immunohistochemical testing, an original hybrid gene testing, and other protein testing, DNA nucleotide and gene testing on the slide specimen. All testing on the slide specimen is enabled to be performed in one same device from the beginning to the end, guaranteeing that all slide specimens are completely covered by the reagent from the beginning to the end, and all slide specimens are carried out the heat treatment at a uniform temperature.Type: GrantFiled: March 21, 2017Date of Patent: January 11, 2022Assignee: XIAMEN TALENT BIOMEDICAL TECHNOLOGY COMPANY, LTD.Inventors: James Guo, Derek Guo
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Patent number: 10830679Abstract: A device for processing a slide specimen and a method thereof, wherein the device mainly comprises a container, a base, a heating device, a slide cover plate, a slide, a slide rack, a liquid outlet, a liquid inlet, a controller, a thermocouple, a temperature display screen, a temperature maintaining time display window and a temperature maintaining time adjustment button. A large amount of slide specimens are enable to carry out processing such as reagent loading, cleaning, heat treatment, temperature maintaining and drying in one same device, realizing that there's no need to take or transfer the slide manually during the whole process of the slide specimen processing, reducing manual intervention and interference, not only saving time but also simplifying the operation steps and reducing operation errors.Type: GrantFiled: March 21, 2017Date of Patent: November 10, 2020Assignee: XIAMEN TALENT BIOMEDICAL TECHNOLOGY COMPANY, LTD.Inventors: James Guo, Derek Guo
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Patent number: 10823647Abstract: A fully-automated biological slide specimen processing device and a method. The device mainly includes a testing assembly, a base platform, a Z-arm, an X-arm, a Y-arm, a dispensing nozzle and scanning devices for identifying a reagent and a specimen. The device in the present invention can automatically realize regular and quantitative dispensing according to testing process requirements and testing steps, automatically control the heating, automatically control liquid filling and liquid discharging, and realize full automation of the testing process. When the slide specimen needs a heat treatment, an insertion slot may be directly filled with liquid and be heated.Type: GrantFiled: March 21, 2017Date of Patent: November 3, 2020Assignee: XIAMEN TALENT BIOMEDICAL TECHNOLOGY COMPANY, LTD.Inventors: James Guo, Derek Guo
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Publication number: 20190101480Abstract: A device for processing a slide specimen and a method thereof, wherein the device mainly comprises a container, a base, a heating device, a slide cover plate, a slide, a slide rack, a liquid outlet, a liquid inlet, a controller, a thermocouple, a temperature display screen, a temperature maintaining time display window and a temperature maintaining time adjustment button. A large amount of slide specimens are enable to carry out processing such as reagent loading, cleaning, heat treatment, temperature maintaining and drying in one same device, realizing that there's no need to take or transfer the slide manually during the whole process of the slide specimen processing, reducing manual intervention and interference, not only saving time but also simplifying the operation steps and reducing operation errors.Type: ApplicationFiled: March 21, 2017Publication date: April 4, 2019Applicant: XIAMEN TALENT BIOMEDICAL TECHNOLOGY COMPANY, LTD.Inventors: James GUO, Derek GUO
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Publication number: 20190101477Abstract: A fully-automated biological slide specimen processing device and a method. The device mainly includes a testing assembly, a base platform, a Z-arm, an X-arm, a Y-arm, a dispensing nozzle and scanning devices for identifying a reagent and a specimen. The device in the present invention can automatically realize regular and quantitative dispensing according to testing process requirements and testing steps, automatically control the heating, automatically control liquid filling and liquid discharging, and realize full automation of the testing process. When the slide specimen needs a heat treatment, an insertion slot may be directly filled with liquid and be heated.Type: ApplicationFiled: March 21, 2017Publication date: April 4, 2019Applicant: XIAMEN TALENT BIOMEDICAL TECHNOLOGY COMPANY, LTD.Inventors: James GUO, Derek GUO
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Publication number: 20190101479Abstract: Provided is a heat treatment device for slide specimen testing, and the heat treatment device mainly includes a container, a base, a heater, a liquid outlet, a liquid inlet, a controller and a thermocouple. When such device is used together with devices such as a slide cover plate and a slide rack, a large amount of slide specimens can be carried out steps of reagent loading, cleaning, heat treatment, temperature maintaining and drying inside one same device, especially multi-step operations such as an immunohistochemical testing, an original hybrid gene testing, and other protein testing, DNA nucleotide and gene testing on the slide specimen. All testing on the slide specimen is enabled to be performed in one same device from the beginning to the end, guaranteeing that all slide specimens are completely covered by the reagent from the beginning to the end, and all slide specimens are carried out the heat treatment at a uniform temperature.Type: ApplicationFiled: March 21, 2017Publication date: April 4, 2019Applicant: XIAMEN TALENT BIOMEDICAL TECHNOLOGY COMPANY, LTD.Inventors: James GUO, Derek GUO
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Publication number: 20190094117Abstract: A slide cover plate for slide specimen processing and an application method thereof. The slide cover plate includes a capillary plane, a depth locating surface, a width locating block, a bottom locating block, a reservoir side surface, a reservoir opening surface and a guiding opening. There's a capillary gap at the middle of a slide assembly formed by fitting the slide cover plate with the slide. During loading, a reagent fills the gap via the capillary siphoning effect, and no matter in which way the slide assembly is placed (placed upright or inclined), the reagent in the gap will not be drained off. When a new reagent is added, the new reagent enters the gap from a reagent loading reservoir, the former reagent existing in the gap flows out from the guiding opening at the bottom of the slide assembly and is replaced by the new reagent automatically. It doesn't require steps of removing and draining the former reagent of the previous step before adding the new reagent.Type: ApplicationFiled: March 21, 2017Publication date: March 28, 2019Applicant: XIAMEN TALENT BIOMEDICAL TECHNOLOGY COMPANY, LTD.Inventors: James GUO, Derek GUO
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Publication number: 20190086303Abstract: A slide rack device for slide specimen processing mainly includes a cover plate, a slide, a slide rack, and a spring piece. The slide rack is provided with a plurality of integrated V-shape insertion slots and a spring piece fixedly disposed inside the V-shape insertion slot. The insertion slot is V-shape and provided upright or inclined, and a plurality of slide assemblies which are assembled by a slide specimen to be tested and the slide cover plate can be closely placed in the insertion slot, so that space utilization is greatly enhanced. It is easy and convenient to assemble or disassemble the slide assembly from the insertion slot. The slide rack can endure higher temperature. When a heat treatment is required in the specimen processing, the slide is inserted in the rack, and then a bottom of the slide is immersed in a hot medium for heating.Type: ApplicationFiled: March 21, 2017Publication date: March 21, 2019Applicant: XIAMEN TALENT BIOMEDICAL TECHNOLOGY COMPANY, LTD.Inventors: James GUO, Derek GUO
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Patent number: D854403Type: GrantFiled: July 5, 2016Date of Patent: July 23, 2019Inventor: James Guo