Patents by Inventor James J. Barry
James J. Barry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240132909Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: October 25, 2023Publication date: April 25, 2024Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: JENNIFER KARA BARRY, JAMES J ENGLISH, KEVIN A. FENGLER, ZHENGLIN HOU, LU LIU, ERIC SCHEPERS, JEFFREY SOPA, INGRID UDRANSZKY
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Publication number: 20200206441Abstract: A nasal delivery device can include a nasal prong and an activation member. The nasal prong can have an opening at a top and bottom portion of the prong to allow for the passage of an aerosolized treatment agent through the nasal prong. The activation member can be positioned on the nasal delivery device at a location that is spaced apart from the subject's oral cavity when the nasal prong is received into the nostril of the subject. The activation member can detect a desired exhalation state of the subject and upon detection of the desired exhalation state, the activation member activates the delivery of the aerosolized treatment agent.Type: ApplicationFiled: February 21, 2020Publication date: July 2, 2020Applicants: The United States of America, as represented by the Secretary, Department of Health & Human Services, Creare LLCInventors: Mark J. Papania, James J. Barry, Mark C. Bagley, James Norris, Darin A. Knaus, Eric M. Friets
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Patent number: 10596334Abstract: A nasal delivery device can include a nasal prong and an activation member. The nasal prong can have an opening at a top and bottom portion of the prong to allow for the passage of an aerosolized treatment agent through the nasal prong. The activation member can be positioned on the nasal delivery device at a location that is spaced apart from the subject's oral cavity when the nasal prong is received into the nostril of the subject. The activation member can detect a desired exhalation state of the subject and upon detection of the desired exhalation state, the activation member activates the delivery of the aerosolized treatment agent.Type: GrantFiled: April 3, 2014Date of Patent: March 24, 2020Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, Creare, IncorporatedInventors: Mark J. Papania, James J. Barry, Mark C. Bagley, James Norris, Darin A. Knaus, Eric M. Friets
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Publication number: 20190009040Abstract: A nasal delivery device can include air-receiving section that has a first passageway therethrough to allow air to pass through the air-receiving section, a powder-reservoir receiving section sized to receive a powder reservoir, and a powder-delivery section that has a second passageway therethrough to allow aerosolized powder from the powder reservoir to pass through the powder-delivery section. The first passageway can have a first end and a second end, with the first end being further from the powder-reservoir receiving section and the second end being at or near the powder-reservoir receiving area. The second end of the air-receiving section can include a flattened region so that air exiting the air-receiving section has a generally flattened profile.Type: ApplicationFiled: September 7, 2018Publication date: January 10, 2019Applicants: The United States of America, as represented by the Secretary, Department of Health and Human Serv, Creare LLCInventors: Mark J. Papania, James J. Barry, Mark C. Bagley, Darin A. Knaus, Eric M. Friets, Edward Moynihan
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Patent number: 10099024Abstract: A nasal delivery device can include air-receiving section that has a first passageway therethrough to allow air to pass through the air-receiving section, a powder-reservoir receiving section sized to receive a powder reservoir, and a powder-delivery section that has a second passageway therethrough to allow aerosolized powder from the powder reservoir to pass through the powder-delivery section. The first passageway can have a first end and a second end, with the first end being further from the powder-reservoir receiving section and the second end being at or near the powder-reservoir receiving area. The second end of the air-receiving section can include a flattened region so that air exiting the air-receiving section has a generally flattened profile.Type: GrantFiled: June 24, 2013Date of Patent: October 16, 2018Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, Creare, IncorporatedInventors: Mark J. Papania, James J. Barry, Mark C. Bagley, Darin A. Knaus, Eric M. Friets, Edward Moynihan
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Publication number: 20170020383Abstract: A nasal delivery device can include a nasal prong and an activation member. The nasal prong can comprises an opening at a top and bottom portion of the prong to allow for the passage of an aerosolized treatment agent through the nasal prong. The activation member can be positioned on the nasal delivery device at a location that is spaced apart from the subject's oral cavity when the nasal prong is received into the nostril of the subject. The activation member can be configured to detect a desired exhalation state of the subject and upon detection of the desired exhalation state, the activation member activates the delivery of the aerosolized treatment agent.Type: ApplicationFiled: October 7, 2016Publication date: January 26, 2017Applicants: The USA, as represented by the Secretary, Department of Health and Human Services, Creare LLCInventors: Mark J. Papania, James J. Barry, Mark C. Bagley, Eric M. Friets, Darin A. Knaus
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Patent number: 9492068Abstract: A nasal delivery device can include a nasal prong and an activation member. The nasal prong can comprises an opening at a top and bottom portion of the prong to allow for the passage of an aerosolized treatment agent through the nasal prong. The activation member can be positioned on the nasal delivery device at a location that is spaced apart from the subject's oral cavity when the nasal prong is received into the nostril of the subject. The activation member can be configured to detect a desired exhalation state of the subject and upon detection of the desired exhalation state, the activation member activates the delivery of the aerosolized treatment agent.Type: GrantFiled: June 3, 2011Date of Patent: November 15, 2016Assignees: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, CREARE LLCInventors: Mark J. Papania, James J. Barry, Mark C. Bagley, Eric M. Friets, Darin A. Knaus
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Publication number: 20160058960Abstract: A nasal delivery device can include a nasal prong and an activation member. The nasal prong can comprises an opening at a top and bottom portion of the prong to allow for the passage of an aerosolized treatment agent through the nasal prong. The activation member can be positioned on the nasal delivery device at a location that is spaced apart from the subject's oral cavity when the nasal prong is received into the nostril of the subject. The activation member can be configured to detect a desired exhalation state of the subject and upon detection of the desired exhalation state, the activation member activates the delivery of the aerosolized treatment agent.Type: ApplicationFiled: April 3, 2014Publication date: March 3, 2016Applicants: The United State of America, as represented by The Secretary, Department of Health and Human Service, Creare IncorporatedInventors: Mark J. Papania, James J. Barry, Mark C. Bagley, James Norris, Darin A. Knaus, Eric M. Friets
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Publication number: 20150136132Abstract: A nasal delivery device can include air-receiving section that has a first passageway therethrough to allow air to pass through the air-receiving section, a powder-reservoir receiving section sized to receive a powder reservoir, and a powder-delivery section that has a second passageway therethrough to allow aerosolized powder from the powder reservoir to pass through the powder-delivery section. The first passageway can have a first end and a second end, with the first end being further from the powder-reservoir receiving section and the second end being at or near the powder-reservoir receiving area. The second end of the air-receiving section can include a flattened region so that air exiting the air-receiving section has a generally flattened profile.Type: ApplicationFiled: June 24, 2013Publication date: May 21, 2015Inventors: Mark J. Papania, James J. Barry, Mark C. Bagley, Darin A. Knaus, Eric M. Friets, Edward Moynihan
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Patent number: 8656908Abstract: Methods and systems for aerosol delivery of agents to a patient are described herein. The present system can be used to administer various types of agents, such as a vaccine or other types of pharmaceutical substances. Certain embodiments of the present system utilize an actuator coupled to a disposable aerosolizing element that aerosolizes an agent for delivery to a patient when acted upon by the actuator. The aerosolizing element prevents the agent from contacting the actuator and other non-disposable components of the system so that little or no cleaning or maintenance is required. The present system also can include an aerosolization rate monitor that monitors the rate at which an agent is being aerosolized and provides feedback to the user to ensure that the proper dose is being administered.Type: GrantFiled: May 2, 2011Date of Patent: February 25, 2014Assignees: The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention, Creare Inc.Inventors: Mark J. Papania, James J. Barry, Mark C. Bagley, Nabil A. Elkouh, Darin Knaus, Robert Trabka
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Publication number: 20130304029Abstract: A medical device, polymer composition, and method for delivering substantially water-insoluble drugs to tissue at desired locations within the body. At least a portion of the exterior surface of the medical device is provided with a polymer coating. Incorporated in the polymer coating is a solution of at least one substantially water-insoluble drug in a volatile organic solvent. The medical device is positioned to a desired target location within the body, whereupon the drug diffuses out of the polymer coating.Type: ApplicationFiled: May 7, 2013Publication date: November 14, 2013Applicant: Boston Scientific Scimed, Inc.Inventors: James J. Barry, Maria Palasis
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Patent number: 8544462Abstract: Aerosol delivery systems and methods for delivering an agent to a patient are described herein. In particular embodiments, an insulated receptacle is connected to a housing and holds a vial of an agent to be delivered to a patient. The vial is located in an inverted position within the receptacle. One or more reusable thermal packs can be located on the inner sides of the receptacle, to maintain a selected temperature surrounding the vial. The agent is administered to a patient by placing a prong into one of the patient's orifices and then activating an aerosol delivery system. Such systems can include jet aerosolization and pneumatic and ultrasonic nebulizers and preferably are portable.Type: GrantFiled: April 27, 2007Date of Patent: October 1, 2013Assignees: The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention, Creare IncorporatedInventors: Mark James Papania, James J. Barry, Nabil A. Elkouh, Mark C. Bagley
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Publication number: 20130072755Abstract: A nasal delivery device can include a nasal prong and an activation member. The nasal prong can comprises an opening at a top and bottom portion of the prong to allow for the passage of an aerosolized treatment agent through the nasal prong. The activation member can be positioned on the nasal delivery device at a location that is spaced apart from the subject's oral cavity when the nasal prong is received into the nostril of the subject. The activation member can be configured to detect a desired exhalation state of the subject and upon detection of the desired exhalation state, the activation member activates the delivery of the aerosolized treatment agent.Type: ApplicationFiled: June 3, 2011Publication date: March 21, 2013Inventors: Mark J. Papania, James J. Barry, Mark C. Bagley, Eric M. Friets, Darin A. Knaus
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Publication number: 20120239001Abstract: A medical device, polymer composition, and method for delivering substantially water-insoluble drugs to tissue at desired locations within the body. At least a portion of the exterior surface of the medical device is provided with a polymer coating. Incorporated in the polymer coating is a solution of at least one substantially water-insoluble drug in a volatile organic solvent. The medical device is positioned to a desired target location within the body, whereupon the drug diffuses out of the polymer coating.Type: ApplicationFiled: May 30, 2012Publication date: September 20, 2012Applicant: Boston Scientific Scimed, Inc.Inventors: James J. Barry, Maria Palasis
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Publication number: 20120203323Abstract: An implant delivery system comprises an implant delivery device having a releasable implant retention region, with the releasable implant retention region having a delivery device coating including a therapeutic agent. The implant delivery device may be a balloon catheter. An implant is releasably positioned in physical communication with the releasable implant retention region. The implant may comprise an implant coating on its inner and/or outer surface, and the implant coating may include a therapeutic agent. The implant may be a stent.Type: ApplicationFiled: April 2, 2012Publication date: August 9, 2012Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: James J. Barry, Sean Gilligan
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Publication number: 20120118283Abstract: Aerosol delivery systems and methods for delivering an agent to a patient are described herein. The present invention includes embodiments comprising an insulated receptacle connected to a body to hold a vial of an agent to be delivered to a patient. The vial is located in an inverted position within the receptacle and connected to the housing. One or more reusable thermal packs can be located on the inner sides of the receptacle, to maintain a selected temperature surrounding the vial. The agent is administered to a patient by placing a prong into one of the patient's orifices and then activating an aerosol delivery system. Such systems comprise jet aerosolization and pneumatic and ultrasonic nebulizers and preferably are portable.Type: ApplicationFiled: April 27, 2007Publication date: May 17, 2012Inventors: Mark James Papania, James J. Barry, Nabil A. Elkouh, Mark C. Bagley
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Patent number: 8157854Abstract: Method and system for delivery of coated implants is provided. One embodiment encompasses a coated implant delivery system. This system includes an implant delivery device having a first end, a second end, and an inner lumen, wherein the first end has a releasable implant retention region with an accessible surface having a coated implant adhesion-resistant treatment. In another embodiment a method of deploying a coated releasable implant at a target site of a vessel using an implant delivery system is provided. This method includes inserting a portion of an implant delivery device having a releasable implant into the vessel, advancing the implant delivery device to the target site, deploying the releasable implant from the delivery device, and withdrawing the inserted portion of the implant delivery device from the vessel.Type: GrantFiled: July 16, 2010Date of Patent: April 17, 2012Assignee: Boston Scientific Scimed, Inc.Inventors: James J. Barry, Sean Gilligan
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Publication number: 20110203580Abstract: Methods and systems for aerosol delivery of agents to a patient are described herein. The present system can be used to administer various types of agents, such as a vaccine or other types of pharmaceutical substances. Certain embodiments of the present system utilize an actuator coupled to a disposable aerosolizing element that aerosolizes an agent for delivery to a patient when acted upon by the actuator. The aerosolizing element prevents the agent from contacting the actuator and other non-disposable components of the system so that little or no cleaning or maintenance is required. The present system also can include an aerosolization rate monitor that monitors the rate at which an agent is being aerosolized and provides feedback to the user to ensure that the proper dose is being administered.Type: ApplicationFiled: May 2, 2011Publication date: August 25, 2011Inventors: Mark J. Papania, James J. Barry, Mark C. Bagley, Nabil A. Elkouh, Darin Knaus, Robert Trabka
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Publication number: 20110196340Abstract: A medical device, polymer composition, and method for delivering substantially water-insoluble drugs to tissue at desired locations within the body. At least a portion of the exterior surface of the medical device is provided with a polymer coating. Incorporated in the polymer coating is a solution of at least one substantially water-insoluble drug in a volatile organic solvent. The medical device is positioned to a desired target location within the body, whereupon the drug diffuses out of the polymer coating.Type: ApplicationFiled: April 13, 2011Publication date: August 11, 2011Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: James J. Barry, Maria Palasis
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Patent number: 7954486Abstract: Methods and systems for aerosol delivery of agents to a patient are described herein. The present system can be used to administer various types of agents, such as a vaccine or other types of pharmaceutical substances. Certain embodiments of the present system utilize an actuator coupled to a disposable aerosolizing element that aerosolizes an agent for delivery to a patient when acted upon by the actuator. The aerosolizing element prevents the agent from contacting the actuator and other non-disposable components of the system so that little or no cleaning or maintenance is required. The present system also can include an aerosolization rate monitor that monitors the rate at which an agent is being aerosolized and provides feedback to the user to ensure that the proper dose is being administered.Type: GrantFiled: April 1, 2005Date of Patent: June 7, 2011Assignees: The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention, Creare Inc.Inventors: Mark J. Papania, James J. Barry, Mark C. Bagley, Nabil A. Elkouh, Darin Knaus, Robert Trabka