Patents by Inventor James J. Barry
James J. Barry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7906133Abstract: The inventors have found that both the drug dose and drug release profiles are significant factors for the safety and efficacy of drug coated stents. The inventors have identified optimum dosing and release kinetics for drug coated stents. In particular, the inventors have determined dosing and release kinetics that permit the delivery of the lowest effective drug dosage, thus enhancing patient safety and minimizing any side effects from the drug.Type: GrantFiled: May 11, 2005Date of Patent: March 15, 2011Assignee: Boston Scientific Scimed, Inc.Inventors: James J. Barry, Kalpana R. Kamath
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Patent number: 7854743Abstract: A catheter for placement of an in situ implant is provided. This catheter may include a first elongate shaft having a proximal end and a distal end, a second elongate shaft having a proximal end and a distal end, a first sharpened distal tip disposed at the distal end of the first shaft and a second sharpened distal tip disposed at the distal end of the second shaft. The first shaft and the second shaft may also be secured to one another at the distal end of the first shaft according to the invention. Still further, according to other teachings, the first sharpened distal tip may extend beyond the second sharpened distal tip in a catheter that practices the invention.Type: GrantFiled: July 21, 2005Date of Patent: December 21, 2010Assignee: Boston Scientific Scimed, Inc.Inventors: Maria Palasis, James J. Barry, Louis Ellis, Gary L. Hendrickson, Kent D. Harrison, Lixiao Wang
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Publication number: 20100280522Abstract: Method and system for delivery of coated implants is provided. One embodiment encompasses a coated implant delivery system. This system includes an implant delivery device having a first end, a second end, and an inner lumen, wherein the first end has a releasable implant retention region with an accessible surface having a coated implant adhesion-resistant treatment. In another embodiment a method of deploying a coated releasable implant at a target site of a vessel using an implant delivery system is provided. This method includes inserting a portion of an implant delivery device having a releasable implant into the vessel, advancing the implant delivery device to the target site, deploying the releasable implant from the delivery device, and withdrawing the inserted portion of the implant delivery device from the vessel.Type: ApplicationFiled: July 16, 2010Publication date: November 4, 2010Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: James J. BARRY, Sean GILLIGAN
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Patent number: 7699804Abstract: A fluid ejection system (20) comprising a cartridge (24), an ejector (32, 300) and, optionally, a fill station (28) for filling the cartridge with a fluid, such as a vaccine. In some embodiments (52), the cartridge includes a transfer passageway (96) for receiving fluid from the fill station. In other embodiments (200, 400), the cartridge includes a vented fluid reservoir (208, 408) offset from an ejection chamber (224, 420). In yet other embodiments (500, 600), the cartridge includes a vented fluid reservoir chamber (512, 636) inline with the ejection chamber (508, 644). In still other embodiments (700, 1000, 1100), the cartridge includes first and second chambers (728, 736, 1036, 1048, 1136, 1148) initially fluidly sealed from on another by a valve, e.g., either a traveling valve (704, 800, 900, 1200, 1300) or a temporarily stationary valve (1004, 1104).Type: GrantFiled: January 30, 2004Date of Patent: April 20, 2010Assignee: Creare Inc.Inventors: James J. Barry, Mark C. Bagley, Peter L. Burghardt, Steven J. Fulton
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Publication number: 20090223513Abstract: Methods and systems for aerosol delivery of agents to a patient are described herein. The present system can be used to administer various types of agents, such as a vaccine or other types of pharmaceutical substances. Certain embodiments of the present system utilize an actuator coupled to a disposable aerosolizing element that aerosolizes an agent for delivery to a patient when acted upon by the actuator. The aerosolizing element prevents the agent from contacting the actuator and other non-disposable components of the system so that little or no cleaning or maintenance is required. The present system also can include an aerosolization rate monitor that monitors the rate at which an agent is being aerosolized and provides feedback to the user to ensure that the proper dose is being administered.Type: ApplicationFiled: April 1, 2005Publication date: September 10, 2009Inventors: Mark J Papania, James J. Barry, Mark C. Bagley, Nabil A. Elkouh, Darin Knaus, Robert Trabka
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Publication number: 20090002941Abstract: A mechanism to reduce liquid intrusion into an internal volume of a computer device. In some embodiments of the invention, air-permeable, hydrophobic means reduces an intrusion of liquid into a computer device by way of an airflow system. In another embodiment, the air-permeable, hydrophobic means includes an air-permeable, hydrophobic membrane. Other embodiments are described and claimed.Type: ApplicationFiled: June 29, 2007Publication date: January 1, 2009Inventors: Rajiv Mongia, Weibo Chen, Michael G. Izenson, James J. Barry
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Patent number: 7445629Abstract: This invention relates generally to medical devices, such as stents, for delivering a biologically active material to a desired location within the body of a patient. In particular, the invention relates generally to a medical device for delivering a biologically active material to a surface of a body lumen. More particularly, the invention is directed to a medical device comprising two opposing end sections, each having a surface, and a middle portion. The middle portion comprises a plurality of struts and the two opposing end sections comprises non-structural elements.Type: GrantFiled: November 11, 2004Date of Patent: November 4, 2008Assignee: Boston Scientific Scimed, Inc.Inventors: Arthur Rosenthal, James J. Barry, Matthew Miller
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Patent number: 7371257Abstract: The invention features a catheter assembly and methods for delivering a hydrogel-lined stent to a body lumen, and methods for lining a stent with a hydrogel. The assembly includes a catheter which has a balloon at least a portion of which is coated with a hydrogel and an expansible stent mounted on the balloon in a contracted condition for passage with the catheter to a site of a body. Expansion of the balloon lodges the stent in the body with hydrogel coated on the inner surfaces of the stent as a lining.Type: GrantFiled: November 23, 2004Date of Patent: May 13, 2008Assignee: Boston Scientific Scimed, Inc.Inventors: Ronald A. Sahatjian, James J. Barry, Maria Palasis
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Patent number: 7225807Abstract: Aerosol delivery systems and methods for delivering an agent to a patient are described herein. The present invention includes embodiments comprising an insulated receptacle connected to a body to hold a vial of an agent to be delivered to a patient. The vial is located in an inverted position within the receptacle and connected to the housing. One or more reusable thermal packs can be located on the inner sides of the receptacle, to maintain a selected temperature surrounding the vial. The agent is administered to a patient by placing a prong into one of the patient's orifices and then activating an aerosol delivery system. Such systems comprise jet aerosolization and pneumatic and ultrasonic nebulizers and preferably are portable.Type: GrantFiled: March 13, 2002Date of Patent: June 5, 2007Assignees: Creare Incorporated, The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and PreventionInventors: Mark James Papania, James J. Barry, Nabil A. Elkouh, Mark C. Bagley
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Patent number: 7066904Abstract: The invention features a method for triggering release of a drug from a hydrogel polymer to tissue at a desired location of the body using a catheter. A portion of the catheter is coated on its outer surface with a polymer having the capacity to incorporate a predetermined substantial amount of drug which is immobilized in the polymer until released by a triggering agent or condition that is different from physiological conditions. Upon contact with a triggering agent or condition, the polymer reacts, e.g., swells or contracts, such that the drug is delivered to the desired body tissue. A balloon catheter is shown in which the hydrogel is carried on the exterior surface of the balloon.Type: GrantFiled: October 25, 2002Date of Patent: June 27, 2006Assignee: Boston Scientific SciMed, Inc.Inventors: Arthur Rosenthal, James J. Barry, Ronald Sahatjian
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Patent number: 6953466Abstract: A method for delivering a therapeutic implant to a tissue is provided. This method includes providing an elongate catheter having a distal end including a lumen, providing a carrier including a therapeutic agent, placing the carrier including the therapeutic agent into the lumen, advancing the distal end of the catheter to the tissue, and depositing the carrier including the therapeutic agent into the tissue.Type: GrantFiled: May 4, 2004Date of Patent: October 11, 2005Assignee: Boston Scientific SciMed, Inc.Inventors: Maria Palasis, James J. Barry, Louis Ellis, Gary L. Hendrickson, Kent D. Harrison, Lixiao Wang
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Patent number: 6908622Abstract: The inventors have found that both the drug dose and drug release profiles are significant factors for the safety and efficacy of drug coated stents. The inventors have identified optimum dosing and release kinetics for drug coated stents. In particular, the inventors have determined dosing and release kinetics that permit the delivery of the lowest effective drug dosage, thus enhancing patient safety and minimizing any side effects from the drug.Type: GrantFiled: September 24, 2002Date of Patent: June 21, 2005Assignee: Boston Scientific SciMed, Inc.Inventors: James J. Barry, Kalpana R. Kamath
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Patent number: 6890339Abstract: The invention features a catheter assembly and methods for delivering a hydrogel-lined stent to a body lumen, and methods for lining a stent with a hydrogel. The assembly includes a catheter which has a balloon at least a portion of which is coated with a hydrogel and an expansible stent mounted on the balloon in a contracted condition for passage with the catheter to a site of a body. Expansion of the balloon lodges the stent in the body with hydrogel coated on the inner surfaces of the stent as a lining.Type: GrantFiled: January 31, 2002Date of Patent: May 10, 2005Assignee: SciMed Life Systems, Inc.Inventors: Ronald A. Sahatjian, James J. Barry, Maria Palasis
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Publication number: 20040228208Abstract: A mixing vial for storing and mixing first and second components includes a mixing container for holding one of the components, and a supplemental container received within the mixing container for holding the other of the components separated from the first component. Manually operable release mechanism is actuatable to produce opening of the supplemental container within the mixing container to permit mixing of the previously segregated components to form a combined mixture in the mixing container.Type: ApplicationFiled: June 22, 2004Publication date: November 18, 2004Applicants: The Government of the United States of America,, The Department of Health and Human Services, Centers for Disease Control and PreventionInventors: Mark James Papania, James J. Barry, Mark C. Bagley
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Publication number: 20040204672Abstract: A method for delivering a therapeutic implant to a tissue is provided. This method includes providing an elongate catheter having a distal end including a lumen, providing a carrier including a therapeutic agent, placing the carrier including the therapeutic agent into the lumen, advancing the distal end of the catheter to the tissue, and depositing the carrier including the therapeutic agent into the tissue.Type: ApplicationFiled: May 4, 2004Publication date: October 14, 2004Inventors: Maria Palasis, James J. Barry, Louis Ellis, Gary L. Hendrickson, Kent D. Harrison, Lixiao Wang
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Publication number: 20040186432Abstract: A fluid ejection system (20) comprising a cartridge (24), an ejector (32, 300) and, optionally, a fill station (28) for filling the cartridge with a fluid, such as a vaccine. In some embodiments (52), the cartridge includes a transfer passageway (96) for receiving fluid from the fill station. In other embodiments (200, 400), the cartridge includes a vented fluid reservoir (208, 408) offset from an ejection chamber (224, 420). In yet other embodiments (500, 600), the cartridge includes a vented fluid reservoir chamber (512, 636) inline with the ejection chamber (508, 644). In still other embodiments (700, 1000, 1100), the cartridge includes first and second chambers (728, 736, 1036, 1048, 1136, 1148) initially fluidly sealed from on another by a valve, e.g., either a traveling valve (704, 800, 900, 1200, 1300) or a temporarily stationary valve (1004, 1104).Type: ApplicationFiled: January 30, 2004Publication date: September 23, 2004Applicant: Creare Inc.Inventors: James J. Barry, Mark C. Bagley, Peter L. Burghardt, Steven J. Fulton
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Publication number: 20040134494Abstract: Aerosol delivery systems and methods for delivering an agent to a patient are described herein. The present invention includes embodiments comprising an insulated receptacle connected to a body to hold a vial of an agent to be delivered to a patient. The vial is located in an inverted position within the receptacle and connected to the housing. One or more reusable thermal packs can be located on the inner sides of the receptacle, to maintain a selected temperature surrounding the vial. The agent is administered to a patient by placing a prong into one of the patient's orifices and then activating an aerosol delivery system. Such systems comprise jet aerosolization and pneumatic and ultrasonic nebulizers and preferably are portable.Type: ApplicationFiled: February 23, 2004Publication date: July 15, 2004Inventors: Mark James Papania, James J. Barry, Nabil A. Elkouh, Marc C. Bagley
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Patent number: 6749617Abstract: A catheter is provided for delivering implants including therapeutic agents to tissues. The catheter is advanceable intra-luminally to place the implants. In one embodiment, the implants include a liquid carrier and therapeutic agent for infusion into the tissue. In another embodiment, a solid carrier includes the therapeutic agent. In yet another embodiment, the implant is formed in situ.Type: GrantFiled: November 8, 2000Date of Patent: June 15, 2004Assignee: SciMed Life Systems, Inc.Inventors: Maria Palasis, James J. Barry
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Publication number: 20040106841Abstract: The invention provides a system which comprises a medical device that delivers a combination of therapies. These therapies include the administration of radiation, biologically active materials, cryotherapy, and thermotherapy. The present invention is also directed to a method of treating body lumen surfaces using the system of the invention. A system is provided for delivering a biologically active material to a surface of a body lumen being exposed to a radioactive source. In one aspect, the system comprises an implantable medical device which has two opposing ends, each having a surface, and a middle portion. The two opposing ends comprise a biologically active material and the middle portion of the medical device is substantially free of any biologically active material. In another aspect, the system delivers a genetic material to a surface of a body lumen which is exposed to a radioactive source.Type: ApplicationFiled: December 2, 2002Publication date: June 3, 2004Inventors: William J. Shaw, James J. Barry, Paul J. Goll, Maria Palasis
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Publication number: 20040009155Abstract: The present invention provides a method of sustaining direct delivery of cells into a target area. The method generally includes delivering cells to a target area. Specifically, the cells are introduced through an introduction site of a target area and delivered to the target area. The method further includes depositing at the introduction site, a plug member that contains a therapeutic agent that is released from the plug member to the target site. at the introduction site. The therapeutic agent generally acts to increase intracellular coupling between the grafted cells and the target area. The plug member also acts to seal the introduction site to inhibit cells from leaking from the introduction site into surrounding areas of the body.Type: ApplicationFiled: July 12, 2002Publication date: January 15, 2004Inventors: Maria Palasis, James J. Barry, Arthur Rosenthal