Patents by Inventor James J. Mitchell

James J. Mitchell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210053990
    Abstract: The present disclosure relates generally to compounds that bind to Acetyl-CoA Carboxylase (ACC) and act as inhibitors of ACC. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of ACC, including liver diseases such as non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH).
    Type: Application
    Filed: August 6, 2020
    Publication date: February 25, 2021
    Inventors: Jamie G. Bates, Ana Z. Gonzalez Buenrostro, Hongyan Guo, Xiaochun Han, Brian J. Kirby, Yurong Lai, Michael L. Mitchell, Gregg M. Schwarzwalder, James G. Taylor, Ting Wang
  • Patent number: 10905094
    Abstract: The System for Continuous Observation of Rodents in Home-cage Environment (SCORHE) was developed to quantify activity levels and behavior patterns for mice housed within a home cage that, optional, may be disposed in a commercial ventilated cage rack. The SCORHE home-cage in-rack design provides daytime and night-time monitoring with the stability and consistency of the home-cage environment. The dual-video camera custom hardware design makes efficient use of space, does not require home-cage modification, and is animal facility user-friendly. In various embodiments, a software application integrates the two video streams to extract several mouse activity measures.
    Type: Grant
    Filed: June 30, 2014
    Date of Patent: February 2, 2021
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Ghadi Salem, John U. Dennis, James B. Mitchell, Thomas J. Pohida
  • Publication number: 20200187976
    Abstract: A medical device for removing a material from a hollow anatomical structure is provided. The device may include a shaft member. The device may include an expandable centering element near the distal end of the device. The device may include a macerator element either attached to the shaft or independent and freely moveable from the shaft. Alternatively, the device may include a rotating wire attached to the macerator element. The device may include an aspiration lumen in for removal of material. The device may include a drive shaft attached to a motor and used to rotate the macerator element. The device may be used in combination with a distal occlusion element, which may be either a radially expandable filter or balloon member.
    Type: Application
    Filed: February 21, 2020
    Publication date: June 18, 2020
    Applicant: AngioDynamics, Inc.
    Inventors: William A. Cartier, William C. Hamilton, JR., James J. Mitchell, Daniel T. Lagoe
  • Patent number: 10668208
    Abstract: Restenosis or neointimal formation may occur following angioplasty or other trauma to an artery such as by-pass surgery. This presents a major clinical problem which narrows the artery. The invention provides a balloon catheter with a particular electrode configuration. Also provided is a method whereby vascular cells in the area of the artery subjected to the trauma are subjected to irreversible electroporation which is a non-thermal, non-pharmaceutical method of applying electrical pulses to the cells so that substantially all of the cells in the area are ablated while leaving the structure of the vessel in place and substantially unharmed due to the non-thermal nature of the procedure.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: June 2, 2020
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, ANGIODYNAMICS, INC.
    Inventors: Boris Rubinsky, Elad Maor, Antoni Ivorra, James J. Mitchell, William C. Hamilton
  • Patent number: 10568654
    Abstract: A medical device for removing a material from a hollow anatomical structure is provided. The device may include a shaft member. The device may include an expandable centering element near the distal end of the device. The device may include a macerator element either attached to the shaft or independent and freely moveable from the shaft. Alternatively, the device may include a rotating wire attached to the macerator element. The device may include an aspiration lumen in for removal of material. The device may include a drive shaft attached to a motor and used to rotate the macerator element. The device may be used in combination with a distal occlusion element, which may he either a radially expandable filter or balloon member.
    Type: Grant
    Filed: May 11, 2015
    Date of Patent: February 25, 2020
    Assignee: AngioDynamics, Inc.
    Inventors: William A Cartier, William C Hamilton, Jr., James J Mitchell, Daniel T Lagoe
  • Publication number: 20190160222
    Abstract: Restenosis or neointimal formation may occur following angioplasty or other trauma to an artery such as by-pass surgery. This presents a major clinical problem which narrows the artery. The invention provides a balloon catheter with a particular electrode configuration. Also provided is a method whereby vascular cells in the area of the artery subjected to the trauma are subjected to irreversible electroporation which is a non-thermal, non-pharmaceutical method of applying electrical pulses to the cells so that substantially all of the cells in the area are ablated while leaving the structure of the vessel in place and substantially unharmed due to the non-thermal nature of the procedure.
    Type: Application
    Filed: May 24, 2018
    Publication date: May 30, 2019
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, ANGIODYNAMICS, INC.
    Inventors: BORIS RUBINSKY, ELAD MAOR, ANTONI IVORRA, JAMES J. MITCHELL, WILLIAM C. HAMILTON
  • Patent number: 10279112
    Abstract: Automated injection system disclosed in this application advantageously provides physicians with a simplified interface for selecting fluid sources, such as saline, contrast, or a mixture of both, to inject at high pressures. The injector system may comprise a multi-use subassembly, a single-use subassembly, a fitting to fluidly connect the multi-use and single-use subassemblies, a hand held controller, a user interface, and an injector housing.
    Type: Grant
    Filed: September 24, 2013
    Date of Patent: May 7, 2019
    Inventors: Eric Houde, Glenn Wadleigh, Todd France, George Bourne, Matthew Cunningham, Gerhard A Foelsche, Gregory T Hughes, Jeffrey Thumm, James J Mitchell, Kirsten Cleveland
  • Patent number: 10010666
    Abstract: Restenosis or neointimal formation may occur following angioplasty or other trauma to an artery such as by-pass surgery. This presents a major clinical problem which narrows the artery. The invention provides a balloon catheter with a particular electrode configuration. Also provided is a method whereby vascular cells in the area of the artery subjected to the trauma are subjected to irreversible electroporation which is a non-thermal, non-pharmaceutical method of applying electrical pulses to the cells so that substantially all of the cells in the area are ablated while leaving the structure of the vessel in place and substantially unharmed due to the non-thermal nature of the procedure.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: July 3, 2018
    Assignees: ANGIODYNAMICS, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Boris Rubinsky, Elad Maor, Antoni Ivorra, James J. Mitchell, William C. Hamilton
  • Publication number: 20160346472
    Abstract: The present disclosure relates to systems and methods for injecting multiple fluids into the vasculature of a patient using a minimal number of valve and stopcock manipulations. In particular, the present disclosure relates to a fluid injection system that combines a contrast source valve and a manifold in-line to a manual or automated syringe assembly for alternately injecting contrast and saline solutions into the vasculature of a patient.
    Type: Application
    Filed: May 31, 2016
    Publication date: December 1, 2016
    Applicant: AngioDynamics, Inc.
    Inventors: James J. Mitchell, Brett Zubiate, Timothy Hall, Reginald Harold Day
  • Patent number: 9470039
    Abstract: A framed architectural mesh panel system including a mesh panel; a frame assembly; and a tensioning system; wherein the tensioning system is integrated within the frame assembly.
    Type: Grant
    Filed: March 18, 2014
    Date of Patent: October 18, 2016
    Assignee: Cambridge International, Inc.
    Inventor: James J. Mitchell
  • Patent number: 9335140
    Abstract: A blast screen system for a framed opening including a mounting mechanism secured to the framed opening; and a flexible mesh panel secured by the mounting mechanism to cover the framed opening. The mounting mechanism includes a plurality of spring biased brackets, each having a first portion and a second portion, the first and second portions being joined by a pivot pin.
    Type: Grant
    Filed: March 18, 2014
    Date of Patent: May 10, 2016
    Assignee: CAMBRIDGE INTERNATIONAL, INC.
    Inventor: James J. Mitchell
  • Publication number: 20150238221
    Abstract: A medical device for removing a material from a hollow anatomical structure is provided. The device may include a shaft member. The device may include an expandable centering element near the distal end of the device. The device may include a macerator element either attached to the shaft or independent and freely moveable from the shaft Alternatively, the device may include a rotating wire attached to the macerator element. The device may include an aspiration lumen in for removal of material. The device may include a drive shaft attached to a motor and used to rotate the macerator element. The device may be used in combination with a distal occlusion element, which may he either a radially expandable filter or balloon member.
    Type: Application
    Filed: May 11, 2015
    Publication date: August 27, 2015
    Applicant: AngioDynamics, Inc.
    Inventors: William A Cartier, William C Hamilton, JR., James J Mitchell, Daniel T Lagoe
  • Publication number: 20150209515
    Abstract: Automated injection system disclosed in this application advantageously provides physicians with a simplified interface for selecting fluid sources, such as saline, contrast, or a mixture of both, to inject at high pressures. The injector system may comprise a multi-use subassembly, a single-use subassembly, a fitting to fluidly connect the multi-use and single-use subassemblies, a hand held controller, a user interface, and an injector housing.
    Type: Application
    Filed: September 24, 2013
    Publication date: July 30, 2015
    Applicant: AngioDynamlcs, Inc.
    Inventors: Eric Houde, Glenn Wadleigh, Todd France, George Bourne, Matthew Cunningham, Gerhard A. Foelsche, Gregory T. Hughes, Jeffrey Thumm, James J. Mitchell, Kirsten Cleveland
  • Patent number: 9055964
    Abstract: A medical device for removing a material from a hollow anatomical structure is provided. The device may include a shaft member. The device may include an expandable centering element near the distal end of the device. The device may include a macerator element either attached to the shaft or independent and freely moveable from the shaft. Alternatively, the device may include a rotating wire attached to the macerator element. The device may include an aspiration lumen in for removal of material. The device may include a drive shaft attached to a motor and used to rotate the macerator element. The device may be used in combination with a distal occlusion element, which may be either a radially expandable filter or balloon member.
    Type: Grant
    Filed: March 15, 2012
    Date of Patent: June 16, 2015
    Assignee: Angio Dynamics, Inc.
    Inventors: William A. Cartier, William C. Hamilton, Jr., James J. Mitchell, Daniel T. Lagoe
  • Patent number: 8881640
    Abstract: A forced entry system for a framed opening including a bracket assembly secured to the framed opening; a mounting tube including a saddle, the saddle being secured to the bracket assembly; and a mesh panel secured by the mounting tube to cover the framed opening.
    Type: Grant
    Filed: July 24, 2012
    Date of Patent: November 11, 2014
    Assignee: Cambridge International Inc.
    Inventors: Trevor J. Errington, James J. Mitchell
  • Publication number: 20140309579
    Abstract: Restenosis or neointimal formation may occur following angioplasty or other trauma to an artery such as by-pass surgery. This presents a major clinical problem which narrows the artery. The invention provides a balloon catheter with a particular electrode configuration. Also provided is a method whereby vascular cells in the area of the artery subjected to the trauma are subjected to irreversible electroporation which is a non-thermal, non-pharmaceutical method of applying electrical pulses to the cells so that substantially all of the cells in the area are ablated while leaving the structure of the vessel in place and substantially unharmed due to the non-thermal nature of the procedure.
    Type: Application
    Filed: June 24, 2014
    Publication date: October 16, 2014
    Applicants: ANGIODYNAMICS, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: BORIS RUBINSKY, ELAD MAOR, ANTONI IVORRA, JAMES J. MITCHELL, WILLIAM C. HAMILTON
  • Publication number: 20140262085
    Abstract: A framed architectural mesh panel system including a mesh panel; a frame assembly; and a tensioning system; wherein the tensioning system is integrated within the frame assembly.
    Type: Application
    Filed: March 18, 2014
    Publication date: September 18, 2014
    Applicant: CAMBRIDGE INTERNATIONAL INC.
    Inventor: James J. MITCHELL
  • Publication number: 20140261109
    Abstract: A blast screen system for a framed opening including a mounting mechanism secured to the framed opening; and a flexible mesh panel secured by the mounting mechanism to cover the framed opening. The mounting mechanism includes a plurality of spring biased brackets, each having a first portion and a second portion, the first and second portions being joined by a pivot pin.
    Type: Application
    Filed: March 18, 2014
    Publication date: September 18, 2014
    Applicant: CAMBRIDGE INTERNATIONAL INC.
    Inventor: James J. MITCHELL
  • Patent number: D719359
    Type: Grant
    Filed: January 24, 2014
    Date of Patent: December 16, 2014
    Assignee: Cambridge International, Inc.
    Inventors: James J. Mitchell, George H. Messick, Jr.
  • Patent number: D864033
    Type: Grant
    Filed: February 2, 2018
    Date of Patent: October 22, 2019
    Assignee: Thor Tech, Inc.
    Inventors: James Jack Owen Devine, Dale Beever, Raymond McKay Featherstone, Bryan M. Fox, Dana Kim Gehman, Bradley J. Mitchell, Robert Owen Sanford, Bryan Thompson