Abstract: A forced entry system for a framed opening including a bracket assembly secured to the framed opening; a mounting tube including a saddle, the saddle being secured to the bracket assembly; and a mesh panel secured by the mounting tube to cover the framed opening.

Abstract: A medical device for removing a material from a hollow anatomical structure is provided. The device may include a shaft member. The device may include an expandable centering element near the distal end of the device. The device may include a macerator element either attached to the shaft or independent and freely moveable from the shaft. Alternatively, the device may include a rotating wire attached to the macerator element. The device may include an aspiration lumen in for removal of material. The device may include a drive shaft attached to a motor and used to rotate the macerator element. The device may be used in combination with a distal occlusion element, which may be either a radially expandable filter or balloon member.

Abstract: Medical template device and method for use in positioning therapeutic probes at a target tissue are provided. The template device includes a frame and a pierceable probe guide secured by the frame. The probe guide has a probe guide pattern such as a grid pattern, wherein the pierceable probe guide is capable of being pierced at any location along its surface by a therapeutic probe. In one embodiment, the pierceable probe guide is a film having a solid surface without any pre-formed apertures. This allows a physician to more accurately position the probes with narrower spacing.

Abstract: Electroporation devices and methods for use in the treatment of complications, such as thrombosis, stenotic segments, or infections, associated with an arteriovenous graft or fistula are provided. The devices include at least two electrodes. The electrodes are adapted to be positioned near the target zone of complication for applying electrical pulses and thereby causing electroporation. In a preferred embodiment, the electroporation pulses are sufficient to subject substantially all cells within the target zone to irreversible electroporation without creating a thermally damaging effect.

Abstract: Restenosis or neointimal formation may occur following angioplasty or other trauma to an artery such as by-pass surgery. This presents a major clinical problem which narrows the artery. The invention provides a balloon catheter with a particular electrode configuration. Also provided is a method whereby vascular cells in the area of the artery subjected to the trauma are subjected to irreversible electroporation which is a non-thermal, non-pharmaceutical method of applying electrical pulses to the cells so that substantially all of the cells in the area are ablated while leaving the structure of the vessel in place and substantially unharmed due to the non-thermal nature of the procedure.

Abstract: Disclosed is a manifold including a housing having multiple ports and multiple bores networking the ports. An actuatable valve, such as a slidable valve, including one or more bores may be positioned in the housing such that the valve is actuatable between a first position and a second position. Actuation of the valve may selectively establish a desired fluid pathway through the manifold. One or more seals may be interposed between the valve and the housing. The seal includes at least a first sealing element, a second sealing element, and a land extending between the sealing elements. The sealing elements are configured to provide a fluid tight seal between the housing and the valve when the valve is in either the first or second position, and the land is configured to provide a fluid tight seal between the housing and the valve when the valve is in an intermediate position.

Abstract: An implantable vascular access port assembly that has a septum, a reservoir, and a catheter connector assembly for use in connecting a catheter with the vascular access port. The catheter connector assembly has an O-ring, an O-ring seal, a locking ring, and a catheter connection plug, which components are located in secured adjacent relationship to one another, respectively, in the vascular access port. The catheter connector assembly securely locks the catheter inside of the vascular access port without compromising the lumen cross-sectional area and can withstand high pressures.