Abstract: System for endocardial injection are disclosed. An example system may include a first steerable catheter having a first lumen formed therein. A second steerable catheter may be disposed within the first lumen. The second steerable catheter may have a second lumen formed therein. An injection catheter may be disposed within the second lumen. The injection catheter may have a distal end region. The distal end region may include an imaging section and a needle section. The system may include an imaging device configured to be disposed within the imaging section.

Abstract: Systems and methods for providing orientation data to a user during a medical procedure performed on a subject are provided. The system can include a medical device, an electrical component and a display device. The medical device is configured to engage a portion the subject and includes a handle. The electrical component is disposed within the handle and is configured to generate data related to an orientation of the medical device during the medical procedure. The display device is physically separate from the medical device and in communication the electrical component. The display device also includes a processor configured to receive and process the data related to the orientation of the medical device, and display information related to the orientation of the medical device to the user based on the data.

Abstract: Systems and methods for calibrating and initializing a system comprising a first qubit, a second qubit, and a coupler are provided. A method of initializing the system can include calibrating the system; providing a first idle resonance frequency of the first qubit and a second idle resonance frequency of the second qubit; providing the first bias for the first idle resonance frequency and the second bias for the second idle resonance frequency; determining a value of the third resonance frequency at which a difference between the first degree of coupling and the second degree of coupling is minimized, when the first resonance frequency is the first idle resonance frequency and the second resonance frequency is the second idle resonance frequency; and providing the third bias according to the determined value of the third resonance frequency.

Abstract: The present technology provides compounds as well as compositions including such compounds useful in targeted radiotherapy of cancer and/or mammalian tissue overexpressing prostate specific membrane antigen (“PSMA”) where the compounds are represented by the following: or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, wherein M1 is independently at each occurrence an alpha-emitting radionuclide. Equivalents of such compounds are also disclosed.

Abstract: A multimode optical waveguide network comprises a parent waveguide and a plurality of child waveguides. Each waveguide is a multimode optical waveguide having a first surface region, multiple second surface regions, and at least one guiding element attached to a surface of the waveguide or embedded within the waveguide, each second surface region of the parent waveguide optically coupled to the first surface region of a corresponding child waveguide. The guiding element(s) of the parent waveguide is arranged to guide a beam, from or to its first surface region, to or from any selected second surface region of its multiple second surface regions. The guiding element(s) of each of the waveguides is configurable for selecting the second surface region of that waveguide and/or responsive to at least one beam characteristic for selecting the second surface region of that waveguide via modulation of the at least one beam characteristic.

Abstract: A tissue-removing catheter for removing tissue in a body lumen includes an elongate body having an axis. A handle is mounted to a proximal end portion of the elongate body. A tissue-removing element is mounted on a distal end portion of the elongate body. An inner liner is received within the elongate body and defines a guidewire lumen. An advancer is mounted on the handle and is movable relative to the housing. The inner liner is coupled to the advancer at a proximal end portion of the inner liner such that movement of the advancer causes a corresponding movement of the inner liner to exert a push force on the tissue-removing element to advance the tissue-removing element and a pull force on the tissue-removing element to retract the tissue-removing element for moving the tissue-removing element relative to the handle.

Abstract: Provided is a vapour generating system with a heatable ceramic wick (300) for vaporizing a liquid. The wick (300) has an aerofoil shape to provide laminar air flow over the wick (300).

Abstract: Wireless communication technologies, a dynamic transaction card, and a mobile application may be utilized to facilitate multi-factor authentication and secure electronic checkout of any website. A wireless connection between a dynamic transaction card and a user device may be utilized to authenticate a user. A user device application may be triggered to call, via an application programming interface (API), an account provider system, and this unique pairing may automatically facilitate payment to a merchant system associated with the electronic check out page.

Abstract: Embodiments of the disclosure are directed to methods, apparatuses, computer-readable media, and systems for network monitoring of communication requests for authorization to an access device. One embodiment is directed at dual message model in a distributed environment with an electronic access device receiving a cancellation signal and generating and sending a reversal message with cancellation information embedded in the data elements of the reversal message to a processor computer, where the cancellation data may be read and saved by the processor computer before the authorization request message is forwarded to be authorized by an authorization entity. The method further comprises generating a cancellation message after the reversal message has processed, where the cancellation message is sent via a transport computer to clear and reconcile the authorization status of the cancelled authorization request with any necessary authorizing or regulatory entities in the network.

Abstract: An electrostatic atomizer electrostatically atomizes a fluid into a charged spray, wherein the charged spray includes a plurality of charged droplets. The electrostatic atomizer includes a chamber forming an inlet and an exit aperture, wherein the chamber is configured for fluid to flow into the chamber from the inlet and to flow out of the chamber from the aperture. An emitter electrode is in liquid contact with the fluid in the chamber and injects an electrical charge into the fluid in the chamber. An impedance circuit is coupled to the chamber and configured to obtain a voltage difference between the emitter electrode and the exit aperture, wherein the voltage difference is at least a minimum voltage threshold.

Abstract: A control system (300) configured to control an active suspension system (104) of a vehicle (100), the control system comprising one or more controller (301), wherein the control system is configured to: determine (702) that the vehicle is travelling on or approaching repeating surface undulations; determine (709) vehicle speed; determine (708) an indication of surface wavelength of the repeating surface undulations; and control (722, 728) the active suspension system to control at least one of a leading wheel suspension frequency and a trailing wheel suspension frequency in dependence on the vehicle speed and surface wavelength.

Abstract: An optical projection system is described that may be used in an optical computing element. The optical projection system has an optical axis and comprises first, second and third lens arrangements. The first and third lens arrangements are rotationally symmetric about the optical axis and are positioned to capture light from an array of sources on a source plane and image the sources onto an output plane. The second lens arrangement is positioned between the first and third lens arrangements. The second lens arrangement has optical power of a first magnitude in a first orientation and optical power of a second magnitude in a second orientation, wherein the first magnitude is larger than the second magnitude and wherein the first orientation is orthogonal to the second orientation and both the first and second orientations are orthogonal to the optical axis.

Abstract: Methods and apparatus for controlling two or more vehicles travelling in formation. Selected vehicles may be fully or partially autonomously controlled; at least one vehicle is partially controlled by a human driver. Information is collected at each vehicle and from the drivers and it is shared with other vehicles and drivers to create a shared world model. Aspects of the shared world model may be presented to the human driver, who may then respond with a control input. Autonomy systems and the drivers on the vehicles then collaborate to make a collective decision to act or not to act and execute any such action in a coordinated manner.

Abstract: The present disclosure arises at least in part from the seminal recognition that a combination treatment regimen including one or more cycles and/or doses of a checkpoint inhibitor and a therapeutic, either sequentially, in either order, or substantially simultaneously, can be more effective in treating cancer in some subjects and/or can initiate, enable, increase, enhance or prolong the activity and/or number of immune cells, or a medically beneficial response by a tumor.

Abstract: Embodiments of the present invention include a convertible prosthesis that is capable of conversion from a humeral head replacement to a reverse reconstruction without any removal of parts integrated into the patient's bony anatomy (e.g. implant stems). A desired overall implant inclination angle may be achieved by matching various implant stems with various reverse inserts, thus permitting a resection surface to be matched with an implant stem selection while also permitting a desired overall implant inclination angle to be achieved through the selection of an appropriate insert.

Abstract: A combination treatment regimen including one or more cycles and/or doses of a checkpoint inhibitor and a therapeutic, either sequentially, in either order, or substantially simultaneously, can be more effective in treating cancer in some subjects and/or can initiate, enable, increase, enhance or prolong the activity and/or number of immune cells, the efficacy of anti-tumor immune responses or a medically beneficial response by a tumor.

Abstract: A process for facilitating environmental conservation is described.

Abstract: The present technology provides compounds as well as compositions including such compounds useful in targeted radiotherapy of cancer and/or mammalian tissue overexpressing prostate specific membrane antigen (“PSMA”) where the compounds are represented by the following: or a pharmaceutical y acceptable salt thereof, or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, wherein M1 is independently at each occurrence an alpha-emitting radionuclide. Equivalents of such compounds are also disclosed.

Abstract: In an optical data transfer system, a beam modulator is configured to embed a set of data in an input beam. A multimode optical waveguide network has an in-coupling region for receiving the input beam. The multimode optical waveguide network is configured to guide the input beam to an out-coupling region of the multimode optical waveguide network. A spatial coherent detector is configured to measure a phase and an amplitude of an output optical field at multiple locations. The output optical field is at least partially defined by the input beam and thus exhibiting distortion effects caused by the passage of the beam through the multimode waveguide network. Signal processing is applied to an output of the spatial coherent detector, in order to compensate for the distortion effects, and thereby recover, from the output of the spatial coherent detector, the set of data embedded in the input beam.