Abstract: A combined gas turbine engine vane and blade outer air seal assembly includes a vane having an airfoil extending from the leading edge to a trailing edge, and has an outer platform. The outer platform has a cooling channel that extends into the airfoil to receive cooling air. The outer platform extends to an integral blade outer air seal to be positioned radially outwardly of a turbine blade in a gas turbine engine. At least a portion of the vane and the blade outer air seal are formed of ceramic matrix composite materials. A gas turbine engine is also disclosed.

Abstract: A combustor includes a combustion chamber and a liner that bounds at least a portion of the combustion chamber. The liner includes a first side facing the combustion chamber and a second side facing away from the combustion chamber. The liner is formed of a lay-up of ceramic matrix composite (CMC) plies that have a first CMC ply on the first side, a second CMC ply on the second side, and intermediate CMC plies between the first and second CMC plies. At least one of the intermediate CMC plies has a pattern of voids that define cooling channels in the combustor panel. The cooling channels are bound on lateral channel sides by the at least one of the intermediate CMC plies.

Abstract: An airfoil includes a platform and an airfoil section. The airfoil section and the platform are formed of a ceramic matrix composite (CMC) having fiber plies and a ceramic matrix, the fiber plies include first and second groups of core fiber plies that respectively define first and second radial tubes that circumscribe first and second internal cavities in the airfoil section. Skin fiber plies define an exterior of the airfoil section, wrap around the first and second groups of core fiber plies, and flare outwardly through a fillet into the platform. Platform fiber plies extend in the platform adjacent the skin fiber plies. There is at least one closed-circuit cooling passage defined in the fiber plies. The cooling passage initiates from the first internal cavity, extends within the platform, and ends at the second internal cavity.

Abstract: An airfoil includes a platform and an airfoil section that are formed of a ceramic matrix composite that includes core fiber plies, skin fiber plies, platform fiber plies, and a cooling passage that extends through selected ones of the plies to provide a cooling circuit through the airfoil section and into the platform.

Abstract: An approach is provided for a thorough and clean way of handling graph overflows in graph execution on single instruction, multiple threads (SIMT) hardware with resumable graph support. The solution does not assume that the input and output fit in the buffers allocated in the SIMT hardware. The approach maintains state of the execution for each kernel and uses multiple iterations of graph execution, making progress in each iteration until all data items are processed through the graph on SIMT hardware. This iterative processing of the graph is transparent to the end user. For resumability, the approach treats buffers as circular buffers instead of serial buffers. With the help of counters, the approach keeps track of the start and end indexes of input and output buffers, thus achieving seamless graph resumability when re-execution is required for only a subset of kernels.

Abstract: Systems, devices and methods of valvular prosthetics having one or more bioresorbable components are described. The bioresorbable components can resorb overtime, allowing the ingrowth of tissue in and around the valvular prosthetic.

Abstract: An apparatus for dual edge memory write operation is provided. The apparatus may include a write enable circuit to receive a write enable signal for writing data to a memory cell, and a write driver circuit to receive a data signal and a complementary data signal, and output a bus signal and a complementary bus signal to the memory cell. The write driver circuit may be coupled to the write enable circuit. The write enable circuit may initiate a write operation to write data to the memory cell based on a falling edge of the write enable signal.

Abstract: In-place recovery of fatal system errors at virtualization hosts. A device identifies an occurrence of a fatal system error in the first instance of a host operating system (OS) executing in a computer system. The device determines to perform an in-place recovery for the fatal system error. The device performs the in-place recovery, including pausing the execution of a virtual machine (VM) by the first instance of the host OS, preserving a state of the VM within system memory of the computer system, and resuming the execution of the VM by a second instance of the host OS executing in the computer system based on the state of the VM that is preserved within the system memory of the computer system.

Abstract: An airfoil includes an airfoil section that defines a trailing edge region that includes a trailing edge. The airfoil section is formed of a ceramic matrix composite that includes core fiber plies and skin fiber plies. The core fiber plies define a radial tube that has a radiused end in the trailing edge region. The skin fiber plies wrap around the core fiber plies and a filler element in the trailing edge region is aft of the internal cavity and is sandwiched between the skin fiber plies on the pressure side and the skin fiber plies on the suction side. There is at least one cooling passage that includes a first, inlet orifice section that opens to the internal cavity at a location forward of the radiused end and that extends through the core fiber plies, and a second, outlet orifice section that extends through the trailing edge.

Abstract: A CMC airfoil includes core fiber plies that define a radial tube that circumscribes an internal cavity, and skin fiber plies that define an exterior of the airfoil section. There is a filler element in the trailing edge region aft of the internal cavity and sandwiched between the skin fiber plies on the pressure side and the skin fiber plies on the suction side. At least one cooling passage includes at least one inlet orifice section that opens to the internal cavity and extends through the core fiber plies, a radially-elongated multi-dimensional plenum connected with the at least one inlet orifice section, a plurality of outlet orifice sections extending through the trailing edge, and a plurality of intermediate passage sections bound by at least one of the skin plies and the filler element and connecting the radially-elongated multi-dimensional plenum with the plurality of outlet orifice sections.

Abstract: The present disclosure provides to graphical user interfaces for controlling a flow therapy apparatus. The graphical user interface can provide a display of flow therapy treatment information and indicators of a patient's health. The graphical user interface can be configured to display the information associated with the patient on one or more user interface screens.

Abstract: A substrate retaining apparatus, a load lock assembly comprising the substrate retaining apparatus, and a system including the substrate retaining apparatus are disclosed. The substrate retaining apparatus can include at least one sidewall and one or more heat shields. One or more of the at least one sidewall can include a cooling fluid conduit to facilitate cooling of substrates retained by the substrate retaining apparatus. Additionally or alternatively, one or more of the at least one sidewall can include a gas conduit to provide gas to a surface of a retained substrate.

Abstract: A system includes processing circuitry communicatively coupled to a coaxial cable as well as a sensor, such as a light detection and ranging (LIDAR) sensor communicatively coupled to an unshielded twisted pair (UTP) cable. The processing circuitry and LIDAR sensor may be communicatively coupled to one another via a UTP-to-coaxial converter that is communicatively coupled to both the coaxial cable and the UTP cable. The UTP-to-coaxial converter includes filter circuitry configured to receive one or more signals generated by the LIDAR sensor and generate one or more filtered signals by blocking a portion of the one or more signals having a frequency in a first frequency range. The UTP-to-coaxial converter is configured to send the one or more filtered signals to the processing circuitry via the coaxial cable.

Abstract: Provided are 6-membered heteroaryl-containing aminopyridine compounds and pharmaceutically acceptable compositions thereof which exhibit inhibition activity against certain mutated forms of EGFR.

Abstract: Provided are 5-membered heteroaryl-containing aminopyridine compounds and pharmaceutically acceptable compositions thereof which exhibit inhibition activity against certain mutated forms of EGFR.

Abstract: Disclosed herein are compounds useful for treating obstructive lung diseases. The compounds are TAS2Rs agonists and may further be used to treat disorders and conditions implicated by TAS2R. In some instances the disclosed compounds can be used to treat asthma.

Abstract: An IC device may include a CMOS layer and memory layers at the frontside and backside of the CMOS layer. The CMOS layer may include one or more logic circuits with MOSFET transistors. The CMOS layer may also include memory cells, e.g., SRAM cells. A memory layer may include one or more memory arrays. A memory array may include memory cells (e.g., DRAM cells), bit lines, and word lines. A logic circuit in the CMOS layer may control access to the memory cells. A memory layer may be bonded with the CMOS layer through a bonding layer that includes conductive structures coupled to a logic circuit in the CMOS layer or to bit lines or word lines in the memory layer. An additional conductive structure may be at the backside of a MOSFET transistor in the CMOS layer and coupled to a conductive structure in the bonding layer.

Abstract: A wearable electronic device may be formed from a layer of fabric having opposing first and second ends. The ends may have first and second respective ear openings that receive a user's ears and may have speakers for playing audio. A soft central portion of the fabric between the ends may overlap the user's eyes. The wearable electronic device may have control circuitry that receives power from a power source. Sensors may be used to gather sensor information such as biometric sensor information. The sensors, control circuitry, and power source may be mounted in a stiff edge portion of the fabric. The stiff edge portion of the fabric may have an elongated strip shape and may extend along an upper edge of the central and the electronic device. Stiffener structures sandwiched between inner and outer layers of the fabric may be used to support speakers.

Abstract: The present invention relates to radiolabeled LPA1 receptor antagonists of Formula (I): or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein, which are useful for the quantitative imaging of LPA1 receptors in mammals.