Patents by Inventor James L. Cook

James L. Cook has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250255293
    Abstract: The present invention provides methods and compositions for decontamination and preservation osteochondral tissue, such as an osteoarticular fracture fragment, meniscus, meniscal tissue, cartilage or other component of a joint or bone tissue fragment autograft, for extended periods of time at room temperature in a tissue storage container or bag. The invention further provides a process for maintaining the sterility of the osteochondral tissue using the apparatus as described.
    Type: Application
    Filed: February 11, 2025
    Publication date: August 14, 2025
    Inventors: James L. Cook, Aaron Stoker, Gregory J. Della Rocca, Julia Nuelle
  • Patent number: 12329427
    Abstract: A TPLO plate configured to accommodate flexible strands (flexible loops) attached to tissue to be attached to bone. The TPLO plate has one or more suture eyelets, to allow the user (surgeon) to pass a flexible strand through the eyelets and attach/reattach the tissue to the plate at the anatomical location, and to improve the rotational stability of the joint or bone. The eyelets may have various shapes, forms and configurations and may be provided on or within a surface of the TPLO bone plate in any number, depending on the characteristics of the fractured bone or bone segments, or of the plate design. The eyelets preferably receive one or more flexible strands.
    Type: Grant
    Filed: July 6, 2022
    Date of Patent: June 17, 2025
    Assignee: ARTHREX, INC.
    Inventors: James R. Dunlop, Gregory Joshua Karnes, Brandon L. Roller, Antonio Pozzi, James L. Cook
  • Patent number: 12213888
    Abstract: An elbow arthroplasty system having a ball and a socket. The ball is configured for coupling to at least one member of one of the following groups: (i) a humerus, and (ii) a radius, an ulna, or both of the radius and the ulna. The socket is configured for coupling to at least one member of the other of the following groups: (i) the humerus, and (ii) the radius, the ulna, or both of the radius and the ulna. The socket defines a cavity that is configured to receive at least a portion of the ball. The ball may be a spheroid, an ellipsoid, a sphere, or a portion of one of the foregoing with a convex surface. The socket may be configured with a concave surface that is spheroidal, ellipsoidal, or spherical and designed to mate with the ball. An elbow arthroplasty method using a ball and a socket.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: February 4, 2025
    Assignee: THE CURATORS OF THE UNIVERSITY OF MISSOURI
    Inventors: James L. Cook, Trent M. Guess, Matthew J. Smith
  • Publication number: 20240361337
    Abstract: Methods for predicting canine hip dysplasia (CHD) in an immature canine subject are provided. The methods include the use of concentration profiles of a plurality of polypeptides, including C2C, CTX-I, CTX-II, RANKL, PIICP, COMP, PINP. Also provided are CHD biomarker profiles for predicting or diagnosing CHD in immature or young canines before CHD develops. Diagnostic reagents and kits for the same are also provided.
    Type: Application
    Filed: May 10, 2024
    Publication date: October 31, 2024
    Inventors: James L. Cook, Aaron M. Stoker, Chantelle C. Bozynski, Keiichi Kuroki, Cristi R. Cook, Emily Leary
  • Patent number: 12005018
    Abstract: The present invention is an apparatus and method for use in a treatment for prevention of arthrofibrosis that includes a first and a second substantially L-shaped frames, each L-shaped frame having a first member and a second member extending from the first member in a substantially perpendicular direction and terminating in a first end, a fixed plate extending between the first members of the L-shaped frames, the fixed plate being parallel with the first members of the L-shaped frames, a movable plate pivotally coupled to the first ends of the first members of the L-shaped frames with, a pneumatic piston coupled to the movable plate and the fixed plate, a hand operated valve operatively coupled to the pneumatic piston and a goniometer coupled to the movable plate and one of the L-shaped frames, the goniometer adapted and configured to indicate the angle between the movable plate and the fixed plate.
    Type: Grant
    Filed: December 23, 2021
    Date of Patent: June 11, 2024
    Assignee: The Curators of the University of Missouri
    Inventors: James L. Cook, Cory Crecelius, Trent Guess, Kylee Rucinski, Jonathan Williams
  • Publication number: 20240164368
    Abstract: The present invention provides a method and apparatus for tissue, such as an allograft, storage and preservation for extended periods of time at room temperature in a sterile tissue culture chamber. The invention further provides a process for maintaining the sterility of tissue using the apparatus as described.
    Type: Application
    Filed: November 27, 2023
    Publication date: May 23, 2024
    Inventors: James L. Cook, Clark T. Hung, Eric Lima, Aaron Stoker
  • Patent number: 11864554
    Abstract: The present invention provides a method and apparatus for tissue, such as an allograft, storage and preservation for extended periods of time at room temperature in a sterile tissue culture chamber. The invention further provides a process for maintaining the sterility of tissue using the apparatus as described.
    Type: Grant
    Filed: October 17, 2022
    Date of Patent: January 9, 2024
    Assignees: The Curators of the University of Missouri, The Trustees of Columbia University in New York
    Inventors: James L. Cook, Clark T. Hung, Eric Lima, Aaron Stoker
  • Publication number: 20230131820
    Abstract: The present invention provides a method and apparatus for tissue, such as an allograft, storage and preservation for extended periods of time at room temperature in a sterile tissue culture chamber. The invention further provides a process for maintaining the sterility of tissue using the apparatus as described.
    Type: Application
    Filed: October 17, 2022
    Publication date: April 27, 2023
    Inventors: James L. Cook, Clark T. Hung, Eric Lima, Aaron Stoker
  • Publication number: 20230068307
    Abstract: A joint motion measurement apparatus includes securing mechanisms that secure sensors to various body parts such as the leg, including the femur, tibia, malleoli and/or calcaneus. The sensors are configured to measure a position and/or motion of the various parts of the leg relative to one another. The sensor data is usable to determine kinematic and/or muscle properties of the leg including knee laxity, tibiofemoral measurements and/or spastic properties.
    Type: Application
    Filed: February 5, 2021
    Publication date: March 2, 2023
    Inventors: Trent M. Guess, James L. Cook, James P. Stannard, Jamie B. Hall
  • Patent number: 11503823
    Abstract: The present invention provides a method and apparatus for tissue, such as an allograft, storage and preservation for extended periods of time at room temperature in a sterile tissue culture chamber. The invention further provides a process for maintaining the sterility of tissue using the apparatus as described.
    Type: Grant
    Filed: September 5, 2019
    Date of Patent: November 22, 2022
    Assignees: The Curators of the University of Missouri, The Trustees of Columbia University
    Inventors: James L. Cook, Clark T. Hung, Eric Lima, Aaron Stoker
  • Publication number: 20220338909
    Abstract: A TPLO plate configured to accommodate flexible strands (flexible loops) attached to tissue to be attached to bone. The TPLO plate has one or more suture eyelets, to allow the user (surgeon) to pass a flexible strand through the eyelets and attach/reattach the tissue to the plate at the anatomical location, and to improve the rotational stability of the joint or bone. The eyelets may have various shapes, forms and configurations and may be provided on or within a surface of the TPLO bone plate in any number, depending on the characteristics of the fractured bone or bone segments, or of the plate design. The eyelets preferably receive one or more flexible strands.
    Type: Application
    Filed: July 6, 2022
    Publication date: October 27, 2022
    Inventors: James R. DUNLOP, Gregory Joshua KARNES, Brandon L. ROLLER, Antonio POZZI, James L. COOK
  • Patent number: 11419648
    Abstract: A TPLO plate configured to accommodate flexible strands (flexible loops) attached to tissue to be attached to bone. The TPLO plate has one or more suture eyelets, to allow the user (surgeon) to pass a flexible strand through the eyelets and attach/reattach the tissue to the plate at the anatomical location, and to improve the rotational stability of the joint or bone. The eyelets may have various shapes, forms and configurations and may be provided on or within a surface of the TPLO bone plate in any number, depending on the characteristics of the fractured bone or bone segments, or of the plate design. The eyelets preferably receive one or more flexible strands.
    Type: Grant
    Filed: February 16, 2022
    Date of Patent: August 23, 2022
    Assignee: ARTHREX, INC.
    Inventors: James R. Dunlop, Gregory Joshua Karnes, Brandon L. Roller, Antonio Pozzi, James L. Cook
  • Publication number: 20220175604
    Abstract: The present invention is an apparatus and method for use in a treatment for prevention of arthrofibrosis that includes a first and a second substantially L-shaped frames, each L-shaped frame having a first member and a second member extending from the first member in a substantially perpendicular direction and terminating in a first end, a fixed plate extending between the first members of the L-shaped frames, the fixed plate being parallel with the first members of the L-shaped frames, a movable plate pivotally coupled to the first ends of the first members of the L-shaped frames with, a pneumatic piston coupled to the movable plate and the fixed plate, a hand operated valve operatively coupled to the pneumatic piston and a goniometer coupled to the movable plate and one of the L-shaped frames, the goniometer adapted and configured to indicate the angle between the movable plate and the fixed plate.
    Type: Application
    Filed: December 23, 2021
    Publication date: June 9, 2022
    Inventors: James L. Cook, Cory Crecelius, Trent Guess, Kylee Rucinski, Jonathan Williams
  • Publication number: 20220168030
    Abstract: A TPLO plate configured to accommodate flexible strands (flexible loops) attached to tissue to be attached to bone. The TPLO plate has one or more suture eyelets, to allow the user (surgeon) to pass a flexible strand through the eyelets and attach/reattach the tissue to the plate at the anatomical location, and to improve the rotational stability of the joint or bone. The eyelets may have various shapes, forms and configurations and may be provided on or within a surface of the TPLO bone plate in any number, depending on the characteristics of the fractured bone or bone segments, or of the plate design. The eyelets preferably receive one or more flexible strands.
    Type: Application
    Filed: February 16, 2022
    Publication date: June 2, 2022
    Inventors: James R. DUNLOP, Gregory Joshua KARNES, Brandon L. ROLLER, Antonio POZZI, James L. COOK
  • Patent number: 11317953
    Abstract: A TPLO plate configured to accommodate flexible strands (flexible loops) attached to tissue to be attached to bone. The TPLO plate has one or more suture eyelets, to allow the user (surgeon) to pass a flexible strand through the eyelets and attach/reattach the tissue to the plate at the anatomical location, and to improve the rotational stability of the joint or bone. The eyelets may have various shapes, forms and configurations and may be provided on or within a surface of the TPLO bone plate in any number, depending on the characteristics of the fractured bone or bone segments, or of the plate design. The eyelets preferably receive one or more flexible strands.
    Type: Grant
    Filed: October 29, 2021
    Date of Patent: May 3, 2022
    Assignee: ARTHREX, INC.
    Inventors: James R. Dunlop, Gregory Joshua Karnes, Brandon L. Roller, Antonio Pozzi, James L. Cook
  • Patent number: 11298167
    Abstract: A TPLO plate configured to accommodate flexible strands (flexible loops) attached to tissue to be attached to bone. The TPLO plate has one or more suture eyelets, to allow the user (surgeon) to pass a flexible strand through the eyelets and attach/reattach the tissue to the plate at the anatomical location, and to improve the rotational stability of the joint or bone. The eyelets may have various shapes, forms and configurations and may be provided on or within a surface of the TPLO bone plate in any number, depending on the characteristics of the fractured bone or bone segments, or of the plate design. The eyelets preferably receive one or more flexible strands.
    Type: Grant
    Filed: June 16, 2021
    Date of Patent: April 12, 2022
    Assignee: ARTHREX, INC.
    Inventors: James R. Dunlop, Gregory Joshua Karnes, Brandon L. Roller, Antonio Pozzi, James L. Cook
  • Publication number: 20220047310
    Abstract: A TPLO plate configured to accommodate flexible strands (flexible loops) attached to tissue to be attached to bone. The TPLO plate has one or more suture eyelets, to allow the user (surgeon) to pass a flexible strand through the eyelets and attach/reattach the tissue to the plate at the anatomical location, and to improve the rotational stability of the joint or bone. The eyelets may have various shapes, forms and configurations and may be provided on or within a surface of the TPLO bone plate in any number, depending on the characteristics of the fractured bone or bone segments, or of the plate design. The eyelets preferably receive one or more flexible strands.
    Type: Application
    Filed: October 29, 2021
    Publication date: February 17, 2022
    Inventors: James R. DUNLOP, Gregory Joshua KARNES, Brandon L. ROLLER, Antonio POZZI, James L. COOK
  • Patent number: 11241353
    Abstract: The present invention is an apparatus and method for use in a treatment for prevention of arthrofibrosis that includes a first and a second substantially L-shaped frames, each L-shaped frame having a first member and a second member extending from the first member in a substantially perpendicular direction and terminating in a first end, a fixed plate extending between the first members of the L-shaped frames, the fixed plate being parallel with the first members of the L-shaped frames, a movable plate pivotally coupled to the first ends of the first members of the L-shaped frames with, a pneumatic piston coupled to the movable plate and the fixed plate, a hand operated valve operatively coupled to the pneumatic piston and a goniometer coupled to the movable plate and one of the L-shaped frames, the goniometer adapted and configured to indicate the angle between the movable plate and the fixed plate.
    Type: Grant
    Filed: November 5, 2018
    Date of Patent: February 8, 2022
    Assignee: The Curators of the University of Missouri
    Inventors: James L. Cook, Cory Crecelius, Trent Guess, Kylee Rucinski, Jonathan Williams
  • Patent number: 11207112
    Abstract: A TPLO plate configured to accommodate flexible strands (flexible loops) attached to tissue to be attached to bone. The TPLO plate has one or more suture eyelets, to allow the user (surgeon) to pass a flexible strand through the eyelets and attach/reattach the tissue to the plate at the anatomical location, and to improve the rotational stability of the joint or bone. The eyelets may have various shapes, forms and configurations and may be provided on or within a surface of the TPLO bone plate in any number, depending on the characteristics of the fractured bone or bone segments, or of the plate design. The eyelets preferably receive one or more flexible strands.
    Type: Grant
    Filed: June 16, 2021
    Date of Patent: December 28, 2021
    Assignee: ARTHREX, INC.
    Inventors: James R. Dunlop, Gregory Joshua Karnes, Brandon L. Roller, Antonio Pozzi, James L. Cook
  • Publication number: 20210307798
    Abstract: A TPLO plate configured to accommodate flexible strands (flexible loops) attached to tissue to be attached to bone. The TPLO plate has one or more suture eyelets, to allow the user (surgeon) to pass a flexible strand through the eyelets and attach/reattach the tissue to the plate at the anatomical location, and to improve the rotational stability of the joint or bone. The eyelets may have various shapes, forms and configurations and may be provided on or within a surface of the TPLO bone plate in any number, depending on the characteristics of the fractured bone or bone segments, or of the plate design. The eyelets preferably receive one or more flexible strands.
    Type: Application
    Filed: June 16, 2021
    Publication date: October 7, 2021
    Inventors: James R. DUNLOP, Gregory Joshua KARNES, Brandon L. ROLLER, Antonio POZZI, James L. COOK