Patents by Inventor James M. Chen

James M. Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20020086890
    Abstract: Compounds of the formula: 1
    Type: Application
    Filed: December 21, 2001
    Publication date: July 4, 2002
    Applicant: American Cyanamid Company
    Inventors: Jeremy I. Levin, Aranapakam M. Venkatesan, James M. Chen, Arie Zask, Vincent P. Sandanayaka, Mila T. Du, Jannie L. Baker
  • Patent number: 6358980
    Abstract: Compounds of the formula: useful in the treatment of arthritis, tumor metastasis, tissue ulceration, abnormal wound healing, periodontal disease, bone disease, diabetes (insulin resistance) and HIV infection.
    Type: Grant
    Filed: January 27, 2000
    Date of Patent: March 19, 2002
    Assignee: American Cyanamid Company
    Inventors: Jeremy I. Levin, Aranapakam M. Venkatesan, James M. Chen, Arie Zask, Vincent P. Sandanayaka, Mila T. Du, Jannie L. Baker
  • Patent number: 6340691
    Abstract: Compounds of the formula are useful in treating disease conditions mediated by TNF-&agr;, such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.
    Type: Grant
    Filed: January 27, 2000
    Date of Patent: January 22, 2002
    Assignee: American Cyanamid Company
    Inventors: Jeremy I. Levin, Aranapakam M. Venkatesan, Derek C. Cole, James M. Chen, Jamie M. Davis, George T. Grosu
  • Publication number: 20010056088
    Abstract: Hydroxamic acids having the formula 1
    Type: Application
    Filed: June 14, 2001
    Publication date: December 27, 2001
    Applicant: American Cyanamid Company
    Inventors: Jeremy I. Levin, James M. Chen
  • Patent number: 6326516
    Abstract: The invention discloses hydroxamide acids of the formula: which are useful in treating disease conditions mediated by TNF-&agr;, such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.
    Type: Grant
    Filed: January 27, 2000
    Date of Patent: December 4, 2001
    Assignee: American Cyanamid Company
    Inventors: Jeremy I. Levin, James M. Chen, Arie Zask
  • Patent number: 6313123
    Abstract: The compounds of formula B: which are useful in disease conditions mediated by TNF-&agr;, such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss
    Type: Grant
    Filed: January 27, 2000
    Date of Patent: November 6, 2001
    Assignee: American Cyanamid Company
    Inventors: Jeremy I. Levin, James M. Chen
  • Patent number: 6277885
    Abstract: Hydroxamic acids having the formula are useful in treating disease conditions mediated by TNF-&agr;, such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.
    Type: Grant
    Filed: January 27, 2000
    Date of Patent: August 21, 2001
    Assignee: American Cyanamid Company
    Inventors: Jeremy I. Levin, James M. Chen
  • Patent number: 6239064
    Abstract: Methods and chemical compositions for treating a gas stream comprising non-halogenated and halogenated organic compounds while suppressing halogenation of the non-halogenated organic compounds with the oxidation products of the halogenated organic compounds in the gas stream are disclosed. The gas stream in the presence of oxygen is contacted with the catalyst compositions of the invention to oxidize the non-halogenated and the halogenated compounds to form water, carbon dioxide, and halogen molecules (Cl2, Br2, etc.) and/or halogen acids such as HCl, HBr, etc. An advantage of the present compositions and methods is that halogenation or of the treated emissions is suppressed over a process operating temperature range 400 to 550° C.
    Type: Grant
    Filed: November 18, 1998
    Date of Patent: May 29, 2001
    Assignee: Engelhard Corporation
    Inventors: Pascaline H. Nguyen, James M. Chen, Chung-Zong Wan, Shau-Lin F. Chen, Zhicheng Hu
  • Patent number: 6225311
    Abstract: Compounds of the formula: are useful in treating disease conditions mediated by TNF-&agr;, such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.
    Type: Grant
    Filed: January 27, 2000
    Date of Patent: May 1, 2001
    Assignee: American Cyanamid Company
    Inventors: Jeremy I. Levin, James M. Chen, Derek C. Cole, Mila T. Du, Leif M. Laakso
  • Patent number: 6200996
    Abstract: Compounds of the formula: are useful in treating disease conditions mediated by TNF-&agr; such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.
    Type: Grant
    Filed: January 27, 2000
    Date of Patent: March 13, 2001
    Assignee: American Cyanamid Company
    Inventors: Jeremy I. Levin, James M. Chen, Frances C. Nelson
  • Patent number: 6193504
    Abstract: A rotary regenerative catalytic oxidizer is disclosed which is a portable, compact system that catalytically destroys VOC and odorous compounds at elevated temperatures of 400 to 800° F. Equipped with a very high thermally efficient rotor of 90+%, most heat for reaction is retained in the apparatus, and the cleaned air at temperatures of 80 to 120 F. is safely discharged into room without causing discomfort. As a portable unit, it can be conveniently used to treat local areas where odorous and/or hazardous VOC and CO compounds are present and conveniently run off household 120V or 220V systems.
    Type: Grant
    Filed: March 30, 1998
    Date of Patent: February 27, 2001
    Assignee: Engelhard Corporation
    Inventors: James M. Chen, James C. Fu, Pascaline H. Nguyen, John J. Steger
  • Patent number: 6042795
    Abstract: Methods and apparatus for the catalytic oxidation treatment of waste gas streams that contain entrained solids and gaseous air pollutants such as volatile organic compounds and carbon monoxide, and particularly methods and apparatus suitable for treating waste gas streams from wood burning processes. The method includes a step of washing the gas stream with water prior to the 5catalytic oxidation treatment.
    Type: Grant
    Filed: September 15, 1995
    Date of Patent: March 28, 2000
    Assignee: Engelhard Corporation
    Inventors: James M. Chen, Pascaline H. Nguyen, Ralph E. Truitt
  • Patent number: 5967771
    Abstract: A system for the abatement of industrial process gases utilizes a rotary regenerative oxidizer comprised of one or more heat exchange beds, each bed comprised of a parallel, axial, and longitudinal array of heat regenerative channels that thermally and/or catalytically oxidize contaminated gases. Utilizing a rotary regenerative oxidizer, and if desired, a plurality of heat regenerative beds incorporated therein, facilitates the use of regenerative technology at lower gas flow rates, increases thermal efficiency, and significantly reduces the floor space normally required when implementing fixed-bed nonrotary regenerative oxidizers. The heat exchange channels may be catalytically treated to enhance oxidation of the pollutants at a lower temperature.
    Type: Grant
    Filed: July 17, 1998
    Date of Patent: October 19, 1999
    Assignee: Engelhard Corporation
    Inventors: James M. Chen, Pascaline H. Nguyen, James C. Fu
  • Patent number: 5919425
    Abstract: Homogeneous catalytic regenerative heat transfer packing material is made by impregnating ceramic packing material with a solution of a catalyst precursor and then fixing the precursor into catalyst form. The catalyzed packing material is suitable for use in a process for the regenerative catalytic oxidation of waste gases, in particular, gases that include volatile organic compounds, carbon monoxide or combinations thereof.
    Type: Grant
    Filed: September 21, 1995
    Date of Patent: July 6, 1999
    Assignee: Engelhard Corporation
    Inventors: Pascaline H. Nguyen, James M. Chen, Bulent O. Yavuz, Howard J. Furbeck
  • Patent number: 5895636
    Abstract: Methods and chemical compositions for treating a gas stream comprising non-halogenated and halogenated organic compounds while suppressing halogenation of the non-halogenated organic compounds with the oxidation products of the halogenated organic compounds in the gas stream are disclosed. The gas stream in the presence of oxygen is contacted with the catalyst compositions of the invention to oxidize the non-halogenated and the halogenated compounds to form water, carbon dioxide, and halogen molecules (Cl.sub.2, Br.sub.2, etc.) and/or halogen acids such as HCl, HBr, etc. An advantage of the present compositions and methods is that halogenation or of the treated emissions is suppressed over a process operating temperature range 400 to 550.degree. C.
    Type: Grant
    Filed: December 2, 1997
    Date of Patent: April 20, 1999
    Assignee: Engelhard Corporation
    Inventors: Pascaline H. Nguyen, James M. Chen, Chung-Zong Wan, Shau-Lin Frank Chen, Zhicheng Hu
  • Patent number: 5874053
    Abstract: A system for the abatement of industrial process emissions comprises a horizontal regenerative catalytic oxidizer (RCO). The system utilizes at least two regenerative chambers and at least two catalytic chambers in a controlled abatement process. Pollutants injected into the RCO from the process emissions are catalytically oxidized. The horizontal configuration of the RCO reduces the size of the RCO per cubic foot of emissions treated, and also simplifies maintenance requirements in removing and replacing, or regenerating, the catalyst. Chutes and valves situated above and below the catalyst provide maintenance means without the associated contamination concerns typically caused by catalytic migration throughout vertically configured RCOs.
    Type: Grant
    Filed: December 1, 1997
    Date of Patent: February 23, 1999
    Assignee: Automotive Systems Laboratory, Inc.
    Inventors: James M. Chen, Richard A. Gay, Sean T. Gribbon
  • Patent number: 5871347
    Abstract: A system for the abatement of industrial process gases utilizes a rotary regenerative oxidizer comprised of one or more heat exchange beds, each bed comprised of a parallel, axial, and longitudinal array of heat regenerative channels that thermally and/or catalytically oxidize contaminated gases. Utilizing a rotary regenerative oxidizer, and if desired, a plurality of heat regenerative beds incorporated therein, facilitates the use of regenerative technology at lower gas flow rates, increases thermal efficiency, and significantly reduces the floor space normally required when implementing fixed-bed nonrotary regenerative oxidizers. The heat exchange channels may be catalytically treated to enhance oxidation of the pollutants at a lower temperature.
    Type: Grant
    Filed: April 1, 1997
    Date of Patent: February 16, 1999
    Assignee: Engelhard Corporation
    Inventors: James M. Chen, Pascaline H. Nguyen, James C. Fu
  • Patent number: 5753197
    Abstract: A system for the abatement of industrial process emissions comprises a horizontal regenerative catalytic oxidizer (RCO). The system utilizes at least two regenerative chambers and at least two catalytic chambers in a controlled abatement process. Pollutants injected into the RCO from the process emissions are catalytically oxidized. The horizontal configuration of the RCO reduces the size of the RCO per cubic foot of emissions treated, and also simplifies maintenance requirements in removing and replacing, or regenerating, the catalyst. Chutes and valves situated above and below the catalyst provide maintenance means without the associated contamination concerns typically caused by catalytic migration throughout vertically configured RCOs.
    Type: Grant
    Filed: November 1, 1996
    Date of Patent: May 19, 1998
    Assignee: Engelhard Corporation
    Inventors: James M. Chen, Richard A. Gay, Sean T. Gribbon
  • Patent number: 5653949
    Abstract: A catalyst and process for treating gas streams which contain halogenated organic compounds, non-halogenated organic compounds, carbon monoxide or mixtures thereof, and particularly gas streams which contain organobromides. The catalyst comprises at least one platinum group metal, zirconium oxide and at least one oxide of manganese, cerium or cobalt.
    Type: Grant
    Filed: June 28, 1996
    Date of Patent: August 5, 1997
    Assignee: Engelhard Corporation
    Inventors: James M. Chen, Pascaline H. Nguyen
  • Patent number: 5643545
    Abstract: A method and device for treating a gas stream comprising at least one non-halogenated carbonaceous compound and optionally at least one halogenated organic compound. The gas stream, at 100.degree. C. to 650.degree. C. and in the presence of oxygen is contacted with a first catalyst in a first catalyst zone. The first catalyst comprises a first catalytic material deposited on a low acidity support material. In this zone, the non-halogenated compound is selectively reacted to form innocuous materials such as water and carbon monoxide. This can be followed by contacting the gas stream with a second catalyst in a second catalyst zone. The second catalyst comprises a second catalytic material deposited on a high acidity support material. In this zone, the halogenated organic compounds are reacted.
    Type: Grant
    Filed: June 8, 1995
    Date of Patent: July 1, 1997
    Assignee: Engelhard Corporation
    Inventors: James M. Chen, Pascaline Nguyen