Patents by Inventor James M. Thompson

James M. Thompson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10952739
    Abstract: Systems for treating an aneurysm in a cerebral vessel and methods of use are described. In one embodiment, the system includes an elongate tubular member having a lumen, an expandable stent, and a delivery device. The expandable stent has a constrained state that is configured for delivery through the lumen of the elongate tubular member, and an expanded state configured for placement within the cerebral vessel adjacent the aneurysm. The delivery device includes an elongate member and a self-expandable portion. The proximal end of the self-expandable portion is coupled to the elongate member at or near the distal end of the elongate member. The self-expandable portion of the delivery device includes a tubular mesh structure having a constrained state and an expanded state. The stent is engaged (e.g., mechanical, frictional, or intermeshing) with the self-expandable portion of the delivery device.
    Type: Grant
    Filed: March 8, 2017
    Date of Patent: March 23, 2021
    Assignee: SEQUENT MEDICAL, INC.
    Inventors: Claudio Plaza, James M Thompson, Hung P Tran
  • Patent number: 10939914
    Abstract: Devices and methods for treatment of a patient's vasculature are described. The device includes a self-expanding resilient permeable shell having a radially constrained state and an expanded state with a globular, axially shortened configuration. The permeable shell may be a single layer of braided elongate filaments having first and second ends that are secured at the proximal end of the permeable shell. The devices may also include permeable shells made of woven braided mesh having a variable mesh density, i.e., the average size of pores in one region are a different than the average size of pores in another region. Methods of using the device to treat a cerebral aneurysm are also described. Methods of forming a tubular braid are also described. Methods of forming a tubular braid with variable braid densities are described. Methods of forming a tubular braid using a castellated mandrel are also described.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: March 9, 2021
    Assignee: SEQUENT MEDICAL, INC.
    Inventors: Todd Hewitt, Brian Merritt, William R. Patterson, James M. Thompson, Claudio Plaza, Hung P. Tran, Richard L Quick
  • Patent number: 10907283
    Abstract: Methods of braiding using a braiding mechanism are described. The braiding machine includes first and second annular members, the second annular member being concentric with the first annular member. A mandrel extends perpendicularly to and intersects a horizontal plane defined by a substantially circular region of the second annular member substantially at the center of the circular region. Each of the annular members has a plurality of tubular guide wires slideably mounted thereon and a plurality of wires extend from the mandrel through each of the tubular wire guides. The first annular member rotates circumferentially relative to the second annular member. The first plurality of tubular wire guides slides radially inward to align with the second annular member, and the second plurality of tubular wire guides slides radially outward so as to align with the first annular member.
    Type: Grant
    Filed: February 27, 2019
    Date of Patent: February 2, 2021
    Assignee: SEQUENT MEDICAL, INC.
    Inventors: James M Thompson, Brian J Cox, Robert Rosenbluth, Philippe Marchand, John Nolting, Darrin J Kent, Tan Q Dinh, Hung P Tran, James A Milburn
  • Patent number: 10383819
    Abstract: A method to effect biphasic bioavailability of oral euphoric psychogenic cannabis. The method comprises the step of providing and ingesting a chambered, layered oral drug delivery arrangement, to achieve both a rapid systemic euphoric cannabis effect, and a delayed, but sustained, systemic cannabis euphoric effect.
    Type: Grant
    Filed: November 5, 2018
    Date of Patent: August 20, 2019
    Assignee: Callitas Therapeutics, Inc.
    Inventors: Ronald J. Thompson, James M. Thompson
  • Publication number: 20190223881
    Abstract: Methods and devices for treating a cerebral aneurysm are described. The device may include a self-expanding resilient permeable shell made from elongate resilient filaments. At least some of the filaments have a distal region that extends beyond the distal end of the permeable shell and form an extension having a generally circular shape when expanded. The permeable shell has a radially constrained elongated state configured for delivery within a microcatheter and has an expanded state with a globular, axially shortened configuration. The permeable shell has a plurality of openings formed between the braided filaments. The distal regions of the plurality of filaments that form the extension may be braided, partially braided, or unraveled. Once deployed within the cerebral aneurysm, the extension is positioned near a dome of the cerebral aneurysm.
    Type: Application
    Filed: April 2, 2019
    Publication date: July 25, 2019
    Applicant: SEQUENT MEDICAL, INC.
    Inventors: TODD HEWITT, Brian E. Merritt, William R. Patterson, James M. Thompson, Claudio Plaza, Hung P. Tran
  • Publication number: 20190218696
    Abstract: Methods of braiding using a braiding mechanism are described. The braiding machine includes first and second annular members, the second annular member being concentric with the first annular member. A mandrel extends perpendicularly to and intersects a horizontal plane defined by a substantially circular region of the second annular member substantially at the center of the circular region. Each of the annular members has a plurality of tubular guide wires slideably mounted thereon and a plurality of wires extend from the mandrel through each of the tubular wire guides. The first annular member rotates circumferentially relative to the second annular member. The first plurality of tubular wire guides slides radially inward to align with the second annular member, and the second plurality of tubular wire guides slides radially outward so as to align with the first annular member.
    Type: Application
    Filed: February 27, 2019
    Publication date: July 18, 2019
    Applicant: SEQUENT MEDICAL, INC.
    Inventors: James M. Thompson, Brian J. Cox, Robert Rosenbluth, Philippe Marchand, John Nolting, Darrin J. Kent, Tan Q. Dinh, Hung P. Tran, James A. Milburn
  • Publication number: 20190125660
    Abstract: A method for providing an orally dissolvable composition of menthol, 1-arginine and one or more cannabinoids for quickly and reliably providing enhanced pharmacokinetic bioavailability of the cannabinoids to a mammalian subject. The orally dissolvable composition is preferably in the form of a thin orally dissolving mucoadhesive strip or film that is placed in the buccal cavity or under the tongue of a user. The menthol and 1-arginine function as permeation enhancers and local vasodilators, providing improved oral transmucosal absorption of the cannabinoids.
    Type: Application
    Filed: September 12, 2018
    Publication date: May 2, 2019
    Applicant: Calitas Therapeutics, Inc
    Inventors: Ronald J. Thompson, James M. Thompson
  • Patent number: 10260182
    Abstract: Methods of braiding using a braiding mechanism are described. The braiding mechanism includes a circular array of filament engagement elements, a mandrel extending from the center of the circular array, a plurality of actuators disposed operably about the circular array, and a rotating mechanism adapted to rotate one or more filaments. The circular array of filament engagement elements and the plurality of actuators are configured to move relative to one another. The plurality of filaments are loaded onto the mandrel and extend radially toward and contact the circumferential edge of the circular array of filament engagement elements. The plurality of actuators are operated to engage a first subset of the plurality of filaments and move the engaged filaments in a generally radial direction to a position beyond the circumferential edge of the circular array. The rotating mechanism is operated to move the engaged filaments about the mandrel axis.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: April 16, 2019
    Assignee: Sequent Medical, Inc.
    Inventors: James M Thompson, Brian J Cox, Robert Rosenbluth, Philippe Marchand, John Nolting, Darrin J Kent, Tan Q Dinh, Hung P Tran, James A Milburn
  • Patent number: 10260183
    Abstract: Methods for forming a tubular braid are described. The method for braiding includes providing a braiding mechanism including a disc, a mandrel, and a plurality of actuators. The disc defines a plane and a circumferential edge and the mandrel extends from a center of the disc. A plurality of filaments are loaded on the mandrel, each extending radially toward the circumferential edge and contacting the disc at a point of engagement. The plurality of actuators are operated to engage and move a first subset of filaments in a generally radial direction to a position beyond the circumferential edge. The disc or the engaged first subset are rotated relative to one another, thereby crossing the first subset over a second subset of filaments. The actuators are then operated to move the first subset to a radial position on the circumferential edge different from its previous point of engagement.
    Type: Grant
    Filed: March 20, 2017
    Date of Patent: April 16, 2019
    Assignee: Sequent Medical, Inc.
    Inventors: Philippe Marchand, John Nolting, Darrin J. Kent, Tan Q. Dinh, Hung P. Tran, James A. Milburn, James M. Thompson
  • Publication number: 20180206849
    Abstract: Devices and methods for treatment of a patient's vasculature are described. The device includes a self-expanding resilient permeable shell having a radially constrained state and an expanded state with a globular, axially shortened configuration. The permeable shell may be a single layer of braided elongate filaments having first and second ends that are secured at the proximal end of the permeable shell. The devices may also include permeable shells made of woven braided mesh having a variable mesh density, i.e., the average size of pores in one region are a different than the average size of pores in another region. Methods of using the device to treat a cerebral aneurysm are also described. Methods of forming a tubular braid are also described. Methods of forming a tubular braid with variable braid densities are described. Methods of forming a tubular braid using a castellated mandrel are also described.
    Type: Application
    Filed: March 23, 2018
    Publication date: July 26, 2018
    Applicant: SEQUENT MEDICAL, INC.
    Inventors: Todd Hewitt, Brian Merritt, William R. Patterson, James M. Thompson, Claudio Plaza, Hung P. Tran, Richard L. Quick
  • Patent number: 10004697
    Abstract: A composition and method are disclosed for optimizing sperm survival and function for couples suffering from male infertility by stimulating and increasing the female sexual partner's vaginal lubrication. An increased amount of vaginal transudate is produced in the female by the topical vulval application of a composition containing menthol or a related cooling compound. The resulting increased amount of vaginal transudate can support the function and viability of the spermatozoa in the hostile vaginal environment and ultimately in the cervical mucus to both capacitate sperm in vivo and to provide a medium for gradient sperm differentiation in the vagina and cervix. The inventive composition and method provides a means to compensate for male infertility caused by abnormal semen quality in order for a couple to successfully achieve conception.
    Type: Grant
    Filed: November 16, 2016
    Date of Patent: June 26, 2018
    Inventors: Ronald J. Thompson, James M. Thompson, Gary A. Thompson
  • Publication number: 20180133167
    Abstract: A composition and method are disclosed for optimizing sperm survival and function for couples suffering from male infertility by stimulating and increasing the female sexual partner's vaginal lubrication. An increased amount of vaginal transudate is produced in the female by the topical vulval application of a composition containing menthol or a related cooling compound. The resulting increased amount of vaginal transudate can support the function and viability of the spermatozoa in the hostile vaginal environment and ultimately in the cervical mucus to both capacitate sperm in vivo and to provide a medium for gradient sperm differentiation in the vagina and cervix. The inventive composition and method provides a means to compensate for male infertility caused by abnormal semen quality in order for a couple to successfully achieve conception.
    Type: Application
    Filed: November 16, 2016
    Publication date: May 17, 2018
    Applicant: M Pharmaceutical USA Inc.
    Inventors: Ronald J. THOMPSON, James M. Thompson, Gary A. Thompson
  • Patent number: 9955976
    Abstract: Devices and methods for treatment of a patient's vasculature are described. The devices include implants made of woven braided mesh having a variable mesh density, i.e., the average size of pores in one region are a different than the average size of pores in another region. Additionally, there is a transition zone between the two regions. The implants have a low profile radially constrained state and an expanded state that is axially shortened. Methods of using the device to treat a cerebral aneurysm are also described. Methods of forming a tubular braid are also described. Methods of forming a tubular braid with variable braid densities are described. Methods of forming a tubular braid using a castellated mandrel are also described.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: May 1, 2018
    Assignee: Sequent Medical, Inc.
    Inventors: Todd J Hewitt, Brian Merritt, William R Patterson, James M Thompson, Claudio Plaza, Hung P Tran
  • Publication number: 20170258473
    Abstract: Systems for treating an aneurysm in a cerebral vessel and methods of use are described. In one embodiment, the system includes an elongate tubular member having a lumen, an expandable stent, and a delivery device. The expandable stent has a constrained state that is configured for delivery through the lumen of the elongate tubular member, and an expanded state configured for placement within the cerebral vessel adjacent the aneurysm. The delivery device includes an elongate member and a self-expandable portion. The proximal end of the self-expandable portion is coupled to the elongate member at or near the distal end of the elongate member. The self-expandable portion of the delivery device includes a tubular mesh structure having a constrained state and an expanded state. The stent is engaged (e.g., mechanical, frictional, or intermeshing) with the self-expandable portion of the delivery device.
    Type: Application
    Filed: March 8, 2017
    Publication date: September 14, 2017
    Applicant: SEQUENT MEDICAL, INC.
    Inventors: CLAUDIO PLAZA, JAMES M. THOMPSON, HUNG P. TRAN
  • Publication number: 20170238541
    Abstract: A method and composition for substituting menthol or a menthol related compound for parabens as a preservative agent in cosmetic and pharmaceutical compositions. The invention provides a means to make cosmetic and pharmaceutical products saber and more marketable by removing all parabens and relying on the antibiotic properties of menthol, or menthol derivatives, to provide antibiotic preservative functions.
    Type: Application
    Filed: February 23, 2016
    Publication date: August 24, 2017
    Applicant: PARALT, LLC
    Inventors: Ronald J. Thompson, James M. Thompson
  • Publication number: 20170239175
    Abstract: A composition and method are disclosed for treating orgasmic disorder in a female subject. The composition is a topical medicament containing tadalafil, menthol, and 1-arginine. The composition typically further comprises an extended release mucoadhesive polymer, and is used for topical application to the clitoris and genital tissues of a human female suffering from orgasmic disorder, which includes difficulty achieving orgasm and anorgasmia. Topical application of the inventive composition to the clitoral mucous membranes and other female genital tissues affects vasodilation and clitoral erection tier an extended period of time and compensates for low testosterone levels in a female subject.
    Type: Application
    Filed: February 19, 2016
    Publication date: August 24, 2017
    Applicant: FSD Pharma Co, LLC
    Inventors: RONALD J. THOMPSON, James M. Thompson
  • Publication number: 20170191195
    Abstract: Methods for forming a tubular braid are described. The method for braiding includes providing a braiding mechanism including a disc, a mandrel, and a plurality of actuators. The disc defines a plane and a circumferential edge and the mandrel extends from a center of the disc. A plurality of filaments are loaded on the mandrel, each extending radially toward the circumferential edge and contacting the disc at a point of engagement. The plurality of actuators are operated to engage and move a first subset of filaments in a generally radial direction to a position beyond the circumferential edge. The disc or the engaged first subset are rotated relative to one another, thereby crossing the first subset over a second subset of filaments. The actuators are then operated to move the first subset to a radial position on the circumferential edge different from its previous point of engagement.
    Type: Application
    Filed: March 20, 2017
    Publication date: July 6, 2017
    Applicant: Sequent Medical, Inc.
    Inventors: PHILIPPE MARCHAND, John Nolting, Darrin J. Kent, Tan Q. Dinh, Hung P. Tran, James A. Milburn, James M. Thompson
  • Publication number: 20170128077
    Abstract: Methods and devices for removing a thrombus are described. The device includes an expandable cylindrical structure made of wires and a self-expanding permeable shell located at the distal end of the cylindrical structure. Methods and devices for treating a cerebral aneurysm are described. The device may include a self-expanding resilient permeable shell and a metallic coil secured to the distal end of the permeable shell.
    Type: Application
    Filed: January 12, 2017
    Publication date: May 11, 2017
    Applicant: SEQUENT MEDICAL, INC.
    Inventors: TODD HEWITT, Brian E. Merritt, William R. Patterson, James M. Thompson, Claudio Plaza, Hung P. Tran
  • Patent number: 9631303
    Abstract: Mechanisms and methods for forming a tubular braid are described. The mechanism for braiding includes a disc, a mandrel, a plurality of catch mechanisms, a plurality of actuators, and a computer program. The disc defines a plane and a circumferential edge. The mandrel extends from a center of the disc and is adapted to hold a plurality of filaments extending radially from the mandrel toward the circumferential edge of the disc. The plurality of catch mechanisms are positioned circumferentially around the edge of the disc and are adapted to engage a filament. The plurality of actuators are configured to move relative to one another and are adapted to move the plurality of catch mechanisms in a substantially radial direction relative to the circumferential edge of the disc.
    Type: Grant
    Filed: July 14, 2014
    Date of Patent: April 25, 2017
    Assignee: Sequent Medical, Inc.
    Inventors: Philippe Marchand, John Nolting, Darrin J Kent, Tan Q Dinh, Hung P Tran, James A Milburn, James M Thompson
  • Patent number: 9629635
    Abstract: Methods and devices for removing a thrombus are described. The device includes an expandable cylindrical structure made of wires and a self-expanding permeable shell located at the distal end of the cylindrical structure. Methods and devices for treating a cerebral aneurysm are described. The device may include a distal self-expanding resilient permeable shell, a proximal self-expanding resilient permeable shell, and an elongate support member positioned between the distal and proximal permeable shells. The elongate support member may be rigid or may be a coil, such as an extension spring. The distal and proximal permeable shells may be made from a plurality of braided filaments, the shells having different pore sizes. The device may also be a braided implant with a force biasing component, such as a coil or generally circular extension, attached to its distal end.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: April 25, 2017
    Assignee: Sequent Medical, Inc.
    Inventors: Todd J Hewitt, Brian Merritt, William R Patterson, James M Thompson, Claudio Plaza, Hung P Tran