Abstract: An access policy analysis system may use stored policy summaries to efficiently perform access analysis. A request that causes an access analysis of an entity in a cloud service provider with respect to a resource hosted in the cloud service provider may be received. An access policy summary generated for the entity based on a set of access policies applied by an access management system of the cloud service provider may be obtained. An access policy summary generated for the resource based on the set of access policies may be obtained. A tree structure that describes a hierarchy of entities in the cloud service provider may be traversed to identify a parent node of the entity in the hierarchy of entities. The access analysis may then be generated based on the access policy summaries for the identified node in the tree structure, for the entity and for the resource.

Abstract: The present disclosure provides methods and compositions related to the modification of immune effector cells to increase therapeutic efficacy. In some embodiments, immune effector cells modified to reduce expression of one or more endogenous target genes, or to reduce one or more functions of an endogenous protein to enhance effector functions of the immune cells are provided. In some embodiments, immune effector cells further modified by introduction of transgenes conferring antigen specificity, such as exogenous T cell receptors (TCRs) or chimeric antigen receptors (CARs) are provided. Methods of treating a cell proliferative disorder, such as a cancer, using the modified immune effector cells described herein are also provided.

Abstract: A method performed by a device registration server is disclosed. The method may include receiving, from a mobile device, location information and data associated with at least one image displayed on at least one display coupled to and co-located with a device, the image being captured by the mobile device. The location information may indicate a location of the mobile device when the at least one image was captured by the mobile device. The method may further include determining that the data received from the mobile device includes device information associated with the device. The method may also include registering the device coupled to and co-located with the at least one display based on the location information and the data received from the mobile device.

Abstract: A pointing controller enables interaction with virtual objects in a virtual or augmented reality environment. The pointing controller comprises a form factor that enables it to be securely positioned in the user's fingers during a pointing gesture. The pointing controller tracks a pointing direction in three-dimensional space based on motion of the pointing controller. The pointing controller furthermore includes one or more control elements such as buttons or touch interfaces to enable additional interactions.

Abstract: The present disclosure provides a method of manufacturing a coral scaffold for use as a bone graft substitute, the method comprising growing coral in a growth medium, removing at least a portion of the coral from the growth medium, and devitalising coral removed from the growth medium, wherein the pH of the growth medium is controlled at a pH of 8.3 or greater, and wherein the growth medium has a carbonate hardness, dKH, is controlled at less than 10.

Abstract: Compounds of Formula (I) wherein the substituents are as defined in claim 1. The invention further relates to herbicidal compositions which comprise a compound of Formula (I) and to the use of compounds of Formula (I) for controlling weeds, in particular in crops of useful plants.

Abstract: Systems and methods are provided for facilitating continuous affinity-based separation of phases in multi-phase formation fluid in a downhole environment. A system can comprise a formation sampler that samples a formation to gather multi-phase formation fluid in a continuous flow through a wellbore during a testing pump out of the formation. The system can also comprise a phase separator comprising one or more affinity-based separators that continuously separates one or more phases of the multi-phase formation fluid through either or both diffusion or flow while downhole in the wellbore during the testing pump out.

Abstract: A computer-implemented method of analysing transcript data, comprising: receiving a plurality of transcripts and a set of outcome data for each transcript, the outcome data associating each transcript with one or more outcomes; receiving a query transcript; processing the query transcript and each transcript within the plurality of transcripts; comparing, the processed data representing the query transcript with the processed data representing the plurality of transcripts, to identify a subset of the plurality of transcripts that meet a threshold similarity criterion with respect to the query transcript; and thereby determining a relationship between the query transcript and one or more outcomes.

Abstract: An enclosure for use as a walk-in freezer or refrigerator, or as a commercial or residential controlled environment building structure includes a first panel and a second panel connected to the first panel. Each of the first and second panels includes a body having a joining beam adhered to the body. The joining beam is comprised of structural material. One or more interior edges of the joining beam are embedded into the panel insulating foam body. An exterior edge of the embedded joining beam defines a joining profile. The joining profile of the first panel may define a groove, and the joining profile of the second panel may define a protrusion configured to engage the groove of the joining member of the first panel. Joined panels may comprise a portion or all of the floor, walls, and ceiling/roof elements of a controlled environment building/enclosure.

Abstract: The present disclosure provides methods of determining the susceptibility of a dog to liver copper accumulation, comprising detecting in a biological sample obtained from the dog the presence or absence in the genome of the dog of one or more polymorphisms, and methods of treating or breeding the dog based on such determination.

Abstract: Systems and methods are provided for determining ion concentration of a fluid downhole using a polymer matrix packaged in a cartridge. An example method can include disposing a cartridge within a flow path of a sensor. The cartridge includes a bracket; a retainer formed of a porous material having pores sized to allow a fluid to flow therethrough; and a substrate comprising a polymer matrix embedded with an ion-indicator, the substrate configured to interact with the fluid and to modify an optical characteristic of the substrate according to an ion concentration of the fluid. The method further includes illuminating the substrate; detecting a change in an optical characteristic of the substrate, the change indicative of the ion concentration of the fluid; and determining the ion concentration of the fluid.

Abstract: A downhole tool to be positioned in a wellbore in a subsurface formation. The downhole tool comprises a first rod configured with a first cavity to obtain samples of formation fluid. The downhole tool comprises a translating member configured to shift the first rod from an open position to a closed position to obtain, via the first cavity, a first fluid sample of the formation fluid from a first location in the wellbore.

Abstract: A system for evaluating a measure of appropriateness of additive manufacturing (AM) to manufacture a vehicle part of a vehicle is provided. The system includes a plurality of data source importers to import a plurality of datasets from a plurality of data sources to a data collection system with a composite dataset including data of the plurality of datasets. The system also includes a dataset manager system (DMS) to manage the data collection system. The system further includes a client application coupled to the DMS. The client application receives a user request for the measure of appropriateness of AM to manufacture the vehicle part of the vehicle during a lifecycle of the vehicle. In response to the user request, the client application produces the measure of appropriateness using an evaluation of a plurality of assessments on the data retrieved from the composite dataset.

Abstract: A vehicle panel includes channels, wherein a first channel includes a first wire capable and a second channel includes a second wire and each wire is capable of carrying at least one of power or a vehicle data signal. The panel also includes a connection point connectable to at least one of a battery or a vehicle computing system, wherein selection of connection between the vehicle computing system or battery to a given connection point provided to a given one of the first or second channels dictates whether the channel carries the vehicle data signal or power. Also, the panel includes holes connecting to the first wire and at least two of the holes connecting to the second wire allowing a connection probe to be inserted into a respective hole to connect to a wire included in a channel to which the hole connects.

Abstract: Systems, methods, and computer-readable media are disclosed for systems and methods for voice-based device operation mode management. Example methods may include determining that a device is coupled to an accessory device, and determining that being coupled to the accessory device triggers activation of a first operation mode at the device. The first operation mode presents digital content at the display in a user interface having a first content density that is less than a second content density of a second operation mode. Example methods may include causing the device to activate the first operation mode, receiving first voice data indicative of a request to change the device operation mode to the second operation mode, and causing the device to activate the second operation mode.

Abstract: A pointing controller worn by a user enables intuitive control of various connected smart devices. Users may indicate which device is to be controlled by pointing in the direction of the smart device (or a proxy object) and performing a predefined action to select the device for control. Once selected, the user may interact with the smart device by performing various gestures or interactions with one or more control elements integrated into the pointing controller. The smart device may provide feedback using visual or auditory indicators on the smart device, or by sending a control signal to the pointing controller or other device in proximity to the user that provides haptic, auditory, or visual feedback.

Abstract: A method for an implement for use with an excavator includes having a radar implement rotatably connected to an arm of the excavator, the radar implement having a ground penetrating radar at a lower surface thereof, rotating the radar implement to a first angle, the arm radially moving the radar implement while maintaining the first angle, collecting output of the ground penetrating radar during the moving, rotating the radar implement to a second angle generally orthogonal to the first angle, the arm radially moving the radar implement while maintaining the second angle, and collecting output of the ground penetrating radar during the second moving.

Abstract: The present invention provides freebase and salt forms of (R)-N-(2-(5-fluoropyridin-3-yl)-8-isopropylpyrazolo[1,5-a][1,3,5]triazin-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-amine, which act as inhibitors of AHR, and compositions and methods thereof, useful for treating various conditions in which the aryl hydrocarbon receptor (AHR) is implicated.

Abstract: A coating system for coating an interior surface of a housing comprising: first and second closures engaging first and second ends, respectively, of the housing to provide an enclosed volume; first and second flow lines coupled to the first and second closures, respectively, the first flow line and/or the second flow line connected to an inert gas source; a reactant gas source(s) comprising a reactant gas and coupled to the first and/or second flow line; and a controller in electronic communication with the reactant gas and inert gas sources, and configured to control flow of inert gas into the enclosed volume, and counter current injection of reactant gas from the reactant gas source(s) into the enclosed volume whereby introduction of pulse(s) of the reactant gas into the enclosed volume are separated by introduction of inert gas into the enclosed volume, and coating layer(s) are deposited on the interior surface.

Abstract: A coating system for coating, with a surface coating process, an interior surface of a housing defining an interior volume, having: a first closure and a second closure to sealingly engage with the housing; one or more first flow lines and second flow lines fluidically coupled to the first and second closure, respectively; a pressurized cell comprising a pressurized gas comprising at least one reactant and at a pressure of greater than a pressure within the housing, wherein the pressurized cell is fluidically coupled to a pressurized cell line comprising one of the first flow lines or second flow lines; and a controller in electronic communication with the pressurized cell and configured to control injection of a pulse of the pressurized gas into a flow of inert gas in the pressurized cell line, whereby the pulse is introduced into the interior volume, coating the interior surface with a coating layer.