Abstract: A system and method for transport management includes a back-end system controlling a display depicting real-time location tracking for drivers or commodities requiring location tracking, route status tracking for driveaway vehicles and towable unites, and freight using a location tracking device including a GPS device connected to a cloud-based infrastructure.

Abstract: A computer-implemented method of analysing transcript data, comprising: receiving a plurality of transcripts and a set of outcome data for each transcript, the outcome data associating each transcript with one or more outcomes; receiving a query transcript; processing the query transcript and each transcript within the plurality of transcripts; comparing, the processed data representing the query transcript with the processed data representing the plurality of transcripts, to identify a subset of the plurality of transcripts that meet a threshold similarity criterion with respect to the query transcript; and thereby determining a relationship between the query transcript and one or more outcomes.

Abstract: A method may comprise positioning a downhole fluid sampling tool into a wellbore, performing a pressure test operation within the wellbore, performing a pumpout operation within the wellbore, identifying when a clean fluid sample may be taken by the downhole fluid sampling tool from at least the pressure test operation and the pumpout operation, and acquiring the clean fluid sample from the wellbore. A system may comprise a downhole fluid sampling tool and an information handling machine. The downhole fluid sampling tool may further comprise one or more probes attached to the downhole fluid sampling tool, one or more stabilizers attached to the downhole fluid sampling tool, and a sensor placed in the downhole fluid sampling tool configured to measure drilling fluid filtrate.

Abstract: There is provided a thermal management apparatus for use with a vehicle comprising: a chassis in thermal contact with one or more first components that require thermal management and one or more second components that require thermal management, wherein the chassis is configured to transfer heat from the one or more first components to the one or more second components.

Abstract: An electronic control unit comprises circuitry to receive a combined signal via a vehicle bus of a vehicle, wherein the combined signal contains a combination of a data signal and a watermark signal, which can be a radio frequency (RF) signal or an analog baseband signal, wherein the data signal includes a message, circuitry to extract a watermark from the watermark signal, circuitry to verify the watermark based on a comparison of the watermark with a pre-defined watermark, circuitry to extract the data signal from the combined signal and obtain the message from the data signal, and circuitry to authenticate the message based on the verification of the watermark.

Abstract: The present disclosure provides methods and compositions related to the modification of immune effector cells to increase therapeutic efficacy. In some embodiments, immune effector cells modified to reduce expression of one or more endogenous target genes, or to reduce one or more functions of an endogenous protein to enhance effector functions of the immune cells are provided. In some embodiments, immune effector cells further modified by introduction of transgenes conferring antigen specificity, such as exogenous T cell receptors (TCRs) or chimeric antigen receptors (CARs) are provided. Methods of treating a cell proliferative disorder, such as a cancer, using the modified immune effector cells described herein are also provided.

Abstract: Embodiments relate to hexagonal fragmentation of terrain. A hive manifest specifying one or more conditions and rules for game level generation using hexagonal terrain tiles is received at a computing device. A set of hexagonal terrain tiles satisfying the one or more conditions and rules specified by the hive manifest are identified. Hexagonal terrain tile definition data corresponding to the identified set of hexagonal terrain tiles is retrieved. A game level using the retrieved hexagonal terrain tile definition data is generated by instantiating a subset of hexagonal terrain tiles of the set of hexagonal terrain tiles as a sub-level of the game level.

Abstract: A method to prevent, inhibit or treat intervertebral disc disease in a mammal and compositions useful in that regard are provided.

Abstract: The present disclosure provides methods and compositions related to the modification of immune effector cells to increase therapeutic efficacy. In some embodiments, immune effector cells modified to reduce expression of one or more endogenous target genes, or to reduce one or more functions of an endogenous protein to enhance effector functions of the immune cells are provided. In some embodiments, immune effector cells further modified by introduction of transgenes conferring antigen specificity, such as exogenous T cell receptors (TCRs) or chimeric antigen receptors (CARs) are provided. Methods of treating a cell proliferative disorder, such as a cancer, using the modified immune effector cells described herein are also provided.

Abstract: In certain embodiments, the present invention provides a method for preventing or treating post-traumatic osteoarthritis (PTOA) in the temporomandibular joint (TMJ) in a subject in need thereof, comprising administrating a pharmaceutical composition comprising an effective amount of mesenchymal stem cell-derived exosomes or mesenchymal stem cell-derived exosomal microRNA to the subject. In certain embodiments, the present invention provides a method for preventing progressive fibrocartilage degeneration in a subject in need thereof, comprising administrating a pharmaceutical composition comprising an effective amount of mesenchymal stem cell-derived exosomes or mesenchymal stem cell-derived exosomal microRNA to the subject.

Abstract: Systems and methods for determining a numerical age for new geological events within a new scheme by ordering relations between geological events within a new scheme and/or within a new scheme and a preexisting scheme into a preferred hierarchy, dynamically excluding lower relations in the preferred hierarchy that conflict with higher relations due to irreconcilable ages of the relations, and using the ordered relations remaining in the preferred hierarchy to determine a numerical age for the new geological events within the new scheme.

Abstract: The present disclosure provides methods and compositions related to the modification of immune effector cells to increase therapeutic efficacy. In some embodiments, immune effector cells modified to reduce expression of one or more endogenous target genes, or to reduce one or more functions of an endogenous protein to enhance effector functions of the immune cells are provided. In some embodiments, immune effector cells further modified by introduction of transgenes conferring antigen specificity, such as exogenous T cell receptors (TCRs) or chimeric antigen receptors (CARs) are provided. Methods of treating a cell proliferative disorder, such as a cancer, using the modified immune effector cells described herein are also provided.

Abstract: Disclosed is a method and a system for autonomously tracking distress events on an aircraft in real-time while in flight. The method involves maintaining a multi-logic classifier configured for identifying distress events, receiving aircraft state data from at least one MAU (main avionics unit), transforming the aircraft state data using the multi-logic classifier to produce transformed state data, producing a trigger event if the transformed state data indicates a distress event, and generating an alert of the trigger event. In accordance with an embodiment of the disclosure, the multi-valued logic classifier is configured for identifying distress events using more than two possible truth values, for example by implementing a fuzzy logic algorithm or an artificial neural network. This is an improvement over conventional methods in which fixed thresholds are used to determine a Boolean true/false value to represent if an aircraft is in distress.

Abstract: A multi-range communication system is provided that can be expanded to support communications using both RF signals and millimeter wave signals without having to install entirely new systems to support communication of the signals. The communication system can use one or more shared optical fibers to simultaneously communicate both RF signals and millimeter wave signals in different ranges between network devices and mobile devices. The communication system permits the co-location of components for the communication system for the different ranges, which can result in substantially similar coverage areas for each of the ranges supported by the communication system. In addition, the corresponding equipment used for communicating signals in each of the ranges can be powered from a common DC power source. The supplied power can be configured for each piece of equipment, and corresponding range, such that the substantially similar coverage areas are obtained.

Abstract: Systems and methods use a three-dimensional snapshot of an infant, child, adolescent, or adult where the subject may have bent legs and an unaligned head position, to provide an estimate of human length. The system identifies anatomical features from the digital information and generates a virtual skeleton. The cumulative distances between pseudo-joints of the virtual skeleton provide an estimate of human length. Comparing length estimates from multiple three-dimensional snapshots of the same individual acquired over time provide an indication of growth of the infant, child, or adolescent. Daily estimates of length can detect growth faltering sooner than less frequent estimates of length, which can lead to timely intervention.

Abstract: A pointing controller enables interaction with virtual objects in a virtual or augmented reality environment. The pointing controller comprises a form factor that enables it to be securely positioned in the user's fingers during a pointing gesture. The pointing controller tracks a pointing direction in three-dimensional space based on motion of the pointing controller. The pointing controller furthermore includes one or more control elements such as buttons or touch interfaces to enable additional interactions.

Abstract: An antenna or radiating element that is constructed of materials allowing for survivability of fire, high temperature, corrosive environments, or any combination of the aforementioned. Antennas are capable of operating for an extended period of time in a high temperature environment with the use of a radome having one or more surfaces covered in one or more of the following surface elements: a polyester film, a moldable plastic film, a boPET product, a ceramifiable silicone rubber material and a ceramic fiber wrap material. The surface elements can be used to construct a portion of the structural components of the antenna.

Abstract: The present invention relates to a method of controlling an ensemble of interacting toy construction models. The interacting toy construction models include toy construction elements having functional toy construction elements, the toy construction elements include coupling members configured for detachably interconnecting the toy construction elements with each other. The functional toy construction elements may perform a function in compliance with a configuration defining a functional behaviour. The method includes configuring the functional toy construction elements in the interacting toy construction models based on information on further functional toy construction elements in said interacting toy construction model to coordinate their functional behaviour in a model-behaviour; and further adapting the model-behaviour based on information on further interacting toy construction models in the ensemble.

Abstract: A pointing controller worn by a user enables intuitive control of various connected smart devices. Users may indicate which device is to be controlled by pointing in the direction of the smart device (or a proxy object) and performing a predefined action to select the device for control. Once selected, the user may interact with the smart device by performing various gestures or interactions with one or more control elements integrated into the pointing controller. The smart device may provide feedback using visual or auditory indicators on the smart device, or by sending a control signal to the pointing controller or other device in proximity to the user that provides haptic, auditory, or visual feedback.

Abstract: The present disclosure provides methods and compositions related to the modification of immune effector cells to increase therapeutic efficacy. In some embodiments, immune effector cells modified to reduce expression of one or more endogenous target genes, or to reduce one or more functions of an endogenous protein to enhance effector functions of the immune cells are provided. In some embodiments, immune effector cells further modified by introduction of transgenes conferring antigen specificity, such as exogenous T cell receptors (TCRs) or chimeric antigen receptors (CARs) are provided. Methods of treating a cell proliferative disorder, such as a cancer, using the modified immune effector cells described herein are also provided.