Abstract: According to the disclosure, a cartridge for detecting a target analyte, comprising: a base comprising a first surface, a second surface opposite to the first surface, and side surfaces connecting between the first surface and the second surface; a chamber recessed from the first surface of the base; and an inflow channel recessed from the first surface of the base and connected to upper portion of the chamber. The chamber comprises an accommodation room for accommodating liquid, an inlet port connected the inflow channel, a guide groove for guiding liquid introduced from the inlet port downward to the accommodation room, and a barrier structure for preventing back flow of liquid from the guide groove toward the inlet port.

Abstract: According to the disclosure, a cartridge for detecting a target analyte, comprising: a base, a sample chamber, a first mixing chamber accommodating a magnetic bead, a second mixing chamber accommodating a dry reagent, a shuttle chamber for dissolving the dry reagent of the second mixing chamber, and a detection chamber for detecting the target analyte. The shuttle chamber is configured to dissolve the dry reagent in a sample solution provided from the first mixing chamber. The fluid in the second mixing chamber is moved to the shuttle chamber by positive pressure provided from the first pneumatic port, or the fluid in the shuttle chamber is moved to the second mixing chamber by negative pressure provided from the first pneumatic port.

Abstract: According to the disclosure, a cartridge for detecting a target analyte mounted on a target analyte detection device, comprising: a base, a plurality of chambers provided on the base and comprising a sample chamber, and a plurality of channels provided on the base and comprising a sample channel connected to the sample chamber. The sample chamber comprises an injection hole provided on the base and comprising an inlet into which the sample is introduced, a sample delivery passage connecting the injection hole, and a sample filter provided on between the outlet of the sample delivery passage and the sample channel. The sample delivery passage comprises an asymmetric cross-sectional shape.

Abstract: According to the disclosure, a cartridge for detecting a target analyte, comprising: a base, a sample chamber, a first mixing chamber accommodating a magnetic bead, a liquid storage chamber storing a liquid, a detection chamber for detecting the target analyte, a plurality of liquid transport channels for transporting fluid of the liquid storage chamber to the first mixing chamber, and a mixing channel connected to the first mixing chamber. The first mixing chamber comprises an opening formed in a first surface of the base, a concave surface provided recessed from the first surface of the base, and a side wall connecting the concave surface and the first surface of the base. At least one of the liquid transport channels is connected to the concave surface of the first mixing chamber.

Abstract: An apparatus configured to detect small particles of a substance suspended in a matrix using ultrasound, may include: a container device configured to receive a sample in an inner volume, including: a first ultrasonic transducer mechanically coupled to or disposed on a first exterior portion of the container device and oriented toward the inner volume, the first ultrasonic transducer may include: a first ultrasonic transmitter; and a first ultrasonic receiver; optionally a first receiver amplifier coupled to the first receiver; optionally the first transmitter amplifier coupled to the first transmitter amplifier; and either: a) a software defined radio (SDR), or b) a signal generator and an oscilloscope, where SDR or signal generator and oscilloscope are electronically coupled to the first ultrasonic transmitter and electronically coupled to the first ultrasonic receiver amplifier; and the electronic controller coupled to the SDR or the signal generator and the oscilloscope.

Abstract: A computer product and methodology is contemplated for adaptively serving hold content during an automated communication session. This includes training a machine learning model with a set of training data that includes a feature of hold duration times during historical automated communication sessions. In response to encountering a computer transaction request during a new automated communication session, a hold time duration is predicted for executing the computer transaction request based on obtaining an inference from the machine learning model. Whether to serve hold content in response to the computer transaction request is determined, based on a comparison of the predicted hold time duration to a predetermined threshold time interval.

Abstract: A computer product and methodology is contemplated for adaptively serving hold content during an automated communication session. This includes training a machine learning model with a set of training data that includes a feature of hold duration times during historical automated communication sessions. In response to encountering a computer transaction request during a new automated communication session, a hold time duration is predicted for executing the computer transaction request based on obtaining an inference from the machine learning model. Whether to serve hold content in response to the computer transaction request is determined, based on a comparison of the predicted hold time duration to a predetermined threshold time interval.

Abstract: An insertion catheter for a circulatory support catheter having a circulatory support device carried by an elongate flexible catheter shaft. The insertion catheter comprises a tubular body with a distal portion configured to axially movably receive the circulatory support device. A diameter of the distal portion is greater than a diameter of a mid portion of the tubular body. The insertion catheter may be inserted into an introducer sheath for delivery of the MCS device. A distal end of the insertion catheter may be located distally of a distal end of the introducer sheath and distally of the arterial bifurcation. The distal portion of the insertion catheter containing the MCS device may be located distally of the bifurcation, with a distal end of the MCS device slightly offset from the distal end of the tubular body.

Abstract: A tachometer system for high-torque rotor for a handheld or spindle-mounted pneumatic tool. There are three main components of the tachometer system. This first main component is a measuring module that includes a photodetector electrically coupled to a cable. The measuring module is fastened inside an air turbine motor assembly with a plurality of exhaust ports. The measuring module is sized to fit within an exhaust bore of the air turbine motor assembly. In one example, the measuring module includes a photodetector mounting plug for firmly holding the photodetector in the exhaust bore of the air turbine motor assembly. Another example of the measuring module includes a photodetector mounting plug for firmly holding the photodetector in the exhaust bore of the air turbine motor assembly.

Abstract: The present invention relates to a continuous process for the production of polyol modified polyalkenylene terephthalates and the application of such polyol modified polyalkylene therephtalate on wire enamels.

Abstract: A medical device for creating elongated incisions within a pericardium is provided. The medical device includes an incision device operably coupled to a distal end of a catheter. The incision device includes an incision channel defined along the incision device. The medical device further includes a retractable cutting apparatus disposed within the incision channel. The retractable cutting apparatus includes a blade structured to move between a retracted position and a deployed position. In an instance in which the blade is in the retracted position, the blade is disposed within the incision channel. In an instance in which the blade is in the deployed position, the blade at least partially protrudes from the incision channel. The medical device further includes a cutting apparatus actuation mechanism structured to move the blade between the retracted position and the deployed position within a human body.

Abstract: A tapered medical access sheath can comprise an access sheath hub and an access sheath shaft extending distally from the access sheath hub. The access sheath shaft can comprise a first delivery lumen extending from a proximal end of the access sheath shaft to a side opening on a distal portion of the access sheath shaft, the first delivery lumen having a width configured to slidably receive a distal portion of a medical device disposed around a guidewire. The access sheath shaft can comprise a tapered distal end portion disposed distally of the side opening. A recess can extend along a longitudinal dimension of the tapered distal end portion from a proximal end to a distal end of the tapered distal end portion. The recess can be in fluid communication with the first delivery lumen and have a width smaller than the diameter of the first delivery lumen.

Abstract: Embodiments herein describe partitioning hardware and software in a system on a chip (SoC) into a hierarchy. In one embodiment, the hierarchy includes three levels of hardware-software configurations, enabling security and/or safety isolation across those three levels. The levels can cover the processor subsystem with compute, memory, acceleration, and peripheral resources shared or divided across those three levels.

Abstract: Disclosed is a medical device comprising an incision assembly coupled to a catheter and an incision opening defined along the incision assembly. A retractable cutting apparatus is disposed within the incision opening and comprises a first incision member comprising at least one first cutting surface and defining a first member proximal end rotatably fixed proximate to a distal end of the incision opening and the at least one cutting surface is located on a bottom edge of the first incision member. A second incision member comprises at least one second cutting surface and defines a second member distal end attached to the first incision member at a connection point between a first member distal end and the first member proximal end of the first incision member, and wherein the at least one second cutting surface is located on a bottom edge of the second incision member.

Abstract: A medical device for creating elongated incisions within a pericardium is provided. The device also includes an incision device operably coupled to a distal end of a catheter. The device also includes a retractable cutting apparatus disposed within an incision channel of the incision device. The retractable cutting apparatus includes a gear-actuated blade structured to move between a retracted and a deployed position. In an instance in which the gear-actuated blade is in the retracted position, the gear-actuated blade is disposed within the incision channel. In an instance in which the gear-actuated blade is in the deployed position, the gear-actuated blade at least partially protrudes from the incision channel. The retractable cutting apparatus also includes a torsion gear mechanism attached to the gear-actuated blade. The retractable cutting apparatus also includes a rotatable gear actuator that is structured to move the torsion gear mechanism.

Abstract: A lock mechanism having a bolt movable between a thrown position and a retracted position, and a deadbolt assembly includes a sliding deadbolt configured to slide between a locked position in which the sliding deadbolt inhibits retraction of the bolt and an unlocked position. The sliding deadbolt includes a first anti-thrust cam configured to restrain the sliding deadbolt in the locked position, and a release driver arranged such that, when driven, the release driver releases the first anti-thrust cam from restraining the sliding deadbolt in the locked position and slides the deadbolt to the unlocked position.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, to adapt a communication service are disclosed. In one aspect, a method includes the actions of maintaining, by a computing device, a communication service that is accessible through a first user interface. The actions further include determining, by the computing device, characteristics of a user who has access to the first user interface. The actions further include, based on the characteristics of the user who has access to the first user interface, determining, by the computing device, a second user interface that is configured to access the communication service. The actions further include providing, by the computing device, the user access to the second user interface that is configured to access the communication service.

Abstract: Systems and methods herein provide for improved email efficiency. Based on selections made while drafting an email, a user requesting a response can cause a calendar reminder to be generated and sent to a recipient for automatic entry on that recipient's electronic calendar. When the original sender indicates that an appropriate response has been received, the system can cause the calendar entry to be removed from the recipient's calendar. The system can also generate automatic reminder emails to prompt the recipient to respond to the sender. The sender can access a list of outstanding email responses that are still due from various recipients and modify the associated reminders as desired.

Abstract: A medical delivery sheath assembly can comprise a first hub portion comprising a first delivery lumen configured to slidably receive at least a portion of a first medical device, and a second hub portion comprising a second delivery lumen configured to slidably receive at least a portion of a second medical device. A longitudinal axis of the first delivery lumen and a longitudinal axis of the second delivery lumen can form an acute angle where a distal portion of the first hub portion and a distal portion of the second hub portion merge. A joint hub portion can be coupled to the distal portion of the first hub portion and the distal portion of the second hub portion. The joint hub portion can comprise a third delivery lumen configured to slidably receive corresponding portions of each the first medical device and the second medical device.

Abstract: Systems and methods herein provide for improved email efficiency. Based on selections made while drafting an email, a user requesting a response can cause a calendar reminder to be generated and sent to a recipient for automatic entry on that recipient's electronic calendar. When the original sender indicates that an appropriate response has been received, the system can cause the calendar entry to be removed from the recipient's calendar. The system can also generate automatic reminder emails to prompt the recipient to respond to the sender. The sender can access a list of outstanding email responses that are still due from various recipients and modify the associated reminders as desired.