Abstract: Aspects of the present disclosure relate to valve skid apparatus and related methods for wellhead systems. A check block of the check valve includes a check side face that interfaces with a gate side face of a gate block of the gate valve. A pump side block is coupled to the gate valve, and a well side block is coupled to the check valve. A first pressure relief valve is coupled to a top face of the pump side block, and a first bleed-off valve is coupled to a top face of the first pressure relief valve. A second pressure relief valve is coupled to a top face of the well side block, and a second bleed-off valve is coupled to a top face of the second pressure relief valve.

Abstract: This invention relates to use of a strain of lactic acid bacteria for inhibiting the growth of methane-producing bacteria and/or archaea in the forestomach of ruminant animals, reducing the ability of the rumen microbiome to produce methane, reducing ruminal methane production and/or for improving feed efficiency, milk production, and/or body weight or body composition of a ruminant animal. Ruminant feed compositions are also provided.

Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells wherein the CAR T cells comprise a CAR and the CAR comprises an E2 anti-fluorescein antibody fragment, and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.

Abstract: A method for forming a transistor with an emitter, intrinsic base, and collector. The base includes a semiconductor layer doped with a conductivity dopant to provide for a lower resistivity path to the intrinsic base. After the formation of a layer over a substrate, an emitter window opening is formed in the layer. The semiconductor layer is formed through the opening by a deposition process. A portion of the semiconductor layer is then removed. An emitter electrode is formed that includes at least a portion located in the opening. A remaining portion of the semiconductor layer is in a conductive path to the intrinsic base.

Abstract: The disclosure is directed to improved methods for preparing substituted quinolinylcyclohexylpropanamide compounds.

Abstract: A heat pump includes a refrigerant loop. The refrigerant loop includes a compressor, a first region of a first heat exchanger, a first branching point, a first shutoff valve, a second shutoff valve, and a second heat exchanger. The compressor includes a low-pressure inlet, a mid-pressure inlet, and an outlet. The first heat exchanger is positioned immediately downstream of the outlet of the compressor. The first branching point is positioned immediately downstream of the first region of the first heat exchanger. The refrigerant loop splits into a first path and a second path at the first branching point. The first shutoff valve is positioned along the first path and immediately downstream of the first branching point. The second shutoff valve is positioned along the second path and immediately downstream of the first branching point. The second heat exchanger is downstream of the first heat exchanger.

Abstract: A button for a drug delivery device with a reduced operating loudness includes a plate-like button body forming a touch surface, wherein the plate-like button body is coupled by an axial supporting member to a noise-generating interface of the drug delivery device and movable into a longitudinal direction of the drug delivery device, wherein the plate-like button body includes a material composite with at least one first component consisting of a first material and at least one second component consisting of a second material different from the first material, wherein the at least one first component and the at least one second component are coupled via at least one coupling plane that is at least sectionwise slanted or perpendicular to the longitudinal direction. Further, the disclosure describes a button assembly for a drug delivery device which is shock resistant.

Abstract: Absorbent product including a laminate of at least two plies, wherein the absorbent product has a measured Y-Connected Area parameter greater than 20 and a Surface Channel Spacing of less than 2.5 mm. The absorbent product has high strength and low machine direction stretch.

Abstract: A system is provided that determines a media item for an insertion in a first media feed of a first channel based on at least a pre-encoded media content, metadata related to the pre-encoded media content, and audience-based parameters. The audience-based parameters include content recognition-based information that corresponds to a live feed of one of a plurality of channels. Each of a plurality of media segments of the pre-encoded media content corresponds to a different quality level and content encryption mode. Based on the audience-based parameters, the media item inserted in the first media feed, and a second programming schedule, a second channel is generated from the first channel. The second programming schedule corresponds to a modified first programming schedule based on the content recognition-based information. Based on at least the media item, a second media feed of the second channel is generated for distribution to a consumer device.

Abstract: A series of fused pentacyclic imidazole derivatives, being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders. In particular, the present invention is concerned with 6, 7-dihydro-7, 14-methanobenzimidazo[1, 2-b][2,5]benzodiazocin-5(14H)-one derivatives and analogs thereof.

Abstract: A system and method for extracting data from an electronic health record to provide provider and patient data similarity scoring includes: encoding a problem list for a plurality of patients with concepts from a common electronic health record ontology. In one aspect, the patients have electronic health records maintained by a plurality of providers. The system and method then may parse the concepts into a plurality of clusters or categories and determining, for each of the providers, a total number of patients that have at least one problem in a cluster or category or determining, for each patient, which of the plurality of clusters or categories correspond to at least one concept encoded in the patient's problem list. The system and method then may calculate for each pair of providers or patients, a distance between the providers or patients.

Abstract: An apparatus for delivering a volatile material in a continuous manner is disclosed. The apparatus includes a delivery engine having a reservoir for containing a volatile material; a rupturable substrate secured to the reservoir; a rupture element positioned adjacent to the rupturable substrate; and a breathable membrane enclosing the reservoir, rupturable substrate and rupture element.

Abstract: System and methods for providing multiple distinct and private video streams, where the streams are temporally and spatially overlapping, and a person uses a visual aid to substantially perceive a single distinct stream from within the multiplicity. A preferred embodiment using two or more projectors comprising a composite of three or more private streams implements the combination of spatial and temporal filtering for steam differentiation. Composite streams from multiple projectors are temporally synchronized, and each composite stream comprises one or more private streams, wherein two or more private streams are temporally interleaved. Each composite stream comprises a succession of spatially composite images. A spatially composite image comprises two or more spatially differentiable private images belonging to different distinct private image streams.

Abstract: In one embodiment, a probe includes a first facet associated with a first pressure port operable to measure a first wind pressure, a second facet associated with a second pressure port operable to measure a second wind pressure, and a third facet associated with a third pressure port operable to measure a third wind pressure. The second facet is adjacent to the first facet and the third facet adjacent to the second facet. The probe further includes a fourth facet adjacent to the third facet and a fifth facet adjacent to the fourth facet and to the first facet. The first facet, the second facet, the third facet, the fourth facet, and the fifth facet are located between a first end portion and a second end portion of the probe.

Abstract: A traction improvement device provides increased traction to a tracked vehicle. The traction improvement device has two opposing brackets that are connected to opposite edges or flanges of a track of a tracked vehicle. A chain extends between the brackets. At least one of the brackets is a tensioner bracket that is configured to adjust the tension of the chain. The tension adjustment provides tension to the chain extending between the brackets, securing the traction improvement device on the outer surface (or gripping surface) of the track.

Abstract: Embodiments relate to using sensor data and location data from a device to generate augmented reality images. A mobile device pose can be determined (a geographic position, direction and a three dimensional orientation of the device) within a location. A type of destination in the location can be identified and multiple destinations can be identified, with the mobile device receiving queue information about the identified destinations from a server. A first image can be captured. Based on the queue information, one of the identified destinations can be selected. The geographic position of each identified destination can be identified, and these positions can be combined with the mobile device pose to generate a second image. Finally, an augmented reality image can be generated by combining the first image and the second image, the augmented reality image identifying the selected one destination.