Patents by Inventor James Paulson

James Paulson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Autoantigens Engineered to Suppress Autoimmune Response
    Publication number: 20240216490
    Abstract: The present disclosure provides engineered antigen compositions that reduce immune response to the antigen in a subject having an immune response to the antigen. The present disclosure also provides pharmaceutical compositions that include such engineered autoantigens and methods for making such engineered autoantigens. Methods for using such engineered antigens as therapeutics and in research are also disclosed.
    Type: Application
    Filed: July 12, 2023
    Publication date: July 4, 2024
    Inventors: Richard James Glynne, Tigran Aivazian, James Paulson
  • High affinity Siglec ligands
    Patent number: 8357671
    Abstract: The invention relates to high affinity Siglec ligands that are useful for isolating cells that express Siglecs and for delivering agents to cells that express Siglecs. In one embodiment, the invention provides a method for treating cancer in a mammal that involves administering a Siglec ligand of the invention to the mammal, where the Siglec ligand is linked to a therapeutic agent.
    Type: Grant
    Filed: November 10, 2006
    Date of Patent: January 22, 2013
    Inventors: James Paulson, Brian Collins, Shoufa Han
  • High Affinity Siglec Ligands
    Publication number: 20090238837
    Abstract: The invention relates to high affinity Siglec ligands that are useful for isolating cells that express Siglecs and for delivering agents to cells that express Siglecs. In one embodiment, the invention provides a method for treating cancer in a mammal that involves administering a Siglec ligand of the invention to the mammal, where the Siglec ligand is linked to a therapeutic agent.
    Type: Application
    Filed: November 10, 2006
    Publication date: September 24, 2009
    Inventors: James Paulson, Brian Collins, Shoufa Han
  • Process for controlling intracellular glycosylation of proteins
    Patent number: 5047335
    Abstract: A process for controlling the glycosylation of protein in a cell wherein the cell is genetically engineered to produce one or more enzymes which provide internal control of the cell's glycosylation mechanism. A Chinese hamster ovary (CHO) cell line is genetically engineered to produce a sialyltransferase. This supplemental sialyltransferase modifies the CHO glycosylation machinery to produce glycoproteins having carbohydrate structures which more closely resemble naturally occurring human glycoproteins.
    Type: Grant
    Filed: December 21, 1988
    Date of Patent: September 10, 1991
    Assignee: The Regents of the University of Calif.
    Inventors: James Paulson, Eryn Ujita-Lee, Jasminder Weinstein