Patents by Inventor James Prentice
James Prentice has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240294989Abstract: The present technology relates to methods for determining whether a patient diagnosed with breast cancer, colorectal cancer, melanoma or lung cancer will benefit from or is predicted to be responsive to treatment with an individual therapeutic agent or a specific combination of therapeutic agents. These methods are based on screening a patient's solid tumors and detecting alterations in target nucleic acid sequences corresponding to a specific set of cancer-related genes. Kits for use in practicing the methods are also provided.Type: ApplicationFiled: May 13, 2024Publication date: September 5, 2024Applicant: Quest Diagnostics Investments LLCInventors: Heather SANDERS, Kevin QU, James PRENTICE, Frederic WALDMAN
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Patent number: 11981966Abstract: The present technology relates to methods for determining whether a patient diagnosed with breast cancer, colorectal cancer, melanoma or lung cancer will benefit from or is predicted to be responsive to treatment with an individual therapeutic agent or a specific combination of therapeutic agents. These methods are based on screening a patient's solid tumors and detecting alterations in target nucleic acid sequences corresponding to a specific set of cancer-related genes. Kits for use in practicing the methods are also provided.Type: GrantFiled: May 8, 2020Date of Patent: May 14, 2024Assignee: Quest Diagnostics Investments LLCInventors: Heather Sanders, Kevin Qu, James Prentice, Frederic Waldman
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Publication number: 20200385817Abstract: The present technology relates to methods for determining whether a patient diagnosed with breast cancer, colorectal cancer, melanoma or lung cancer will benefit from or is predicted to be responsive to treatment with an individual therapeutic agent or a specific combination of therapeutic agents. These methods are based on screening a patient's solid tumors and detecting alterations in target nucleic acid sequences corresponding to a specific set of cancer-related genes. Kits for use in practicing the methods are also provided.Type: ApplicationFiled: May 8, 2020Publication date: December 10, 2020Applicant: Quest Diagnostics Investments LLCInventors: Heather Sanders, Kevin QU, James PRENTICE, Frederic WALDMAN
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Patent number: 10689710Abstract: The present technology relates to methods for determining whether a patient diagnosed with breast cancer, colorectal cancer, melanoma or lung cancer will benefit from or is predicted to be responsive to treatment with an individual therapeutic agent or a specific combination of therapeutic agents. These methods are based on screening a patient's solid tumors and detecting alterations in target nucleic acid sequences corresponding to a specific set of cancer-related genes. Kits for use in practicing the methods are also provided.Type: GrantFiled: October 28, 2015Date of Patent: June 23, 2020Assignee: Quest Diagnostics Investments IncorporatedInventors: Heather Sanders, Kevin Qu, James Prentice, Frederic Waldman
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Publication number: 20180142304Abstract: The present technology relates to methods for determining whether a patient diagnosed with breast cancer, colorectal cancer, melanoma or lung cancer will benefit from or is predicted to be responsive to treatment with an individual therapeutic agent or a specific combination of therapeutic agents. These methods are based on screening a patient's solid tumors and detecting alterations in target nucleic acid sequences corresponding to a specific set of cancer-related genes. Kits for use in practicing the methods are also provided.Type: ApplicationFiled: October 28, 2015Publication date: May 24, 2018Applicant: Quest Diagnostics Investments IncorporatedInventors: Heather SANDERS, Kevin QU, James PRENTICE, Frederic WALDMAN
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Publication number: 20110306518Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.Type: ApplicationFiled: August 22, 2011Publication date: December 15, 2011Applicant: XDx, Inc.Inventors: Jay WOHLGEMUTH, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice, MacDonald Morris, Steven Rosenberg
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Publication number: 20110104697Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.Type: ApplicationFiled: January 5, 2011Publication date: May 5, 2011Applicant: XDx, Inc.Inventors: Jay WOHLGEMUTH, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice, MacDonald Morris, Steven Rosenberg
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Patent number: 7892745Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.Type: GrantFiled: September 8, 2009Date of Patent: February 22, 2011Assignee: XDx, Inc.Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice, MacDonald Morris, Steven Rosenberg
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Patent number: 7879556Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.Type: GrantFiled: August 12, 2010Date of Patent: February 1, 2011Assignee: XDx, Inc.Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice, MacDonald Morris, Steven Rosenberg
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Publication number: 20100317018Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.Type: ApplicationFiled: August 12, 2010Publication date: December 16, 2010Applicant: XDx, Inc.Inventors: Jay WOHLGEMUTH, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice, MacDonald Morris, Steven Rosenberg
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Patent number: 7785797Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.Type: GrantFiled: August 19, 2009Date of Patent: August 31, 2010Assignee: XDx, Inc.Inventors: Jay Wohlgemuth, Kirk E. Fry, Robert Woodward, Ngoc Ly, James Prentice, Macdonald Morris, Steven Rosenberg
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Publication number: 20100151467Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.Type: ApplicationFiled: September 8, 2009Publication date: June 17, 2010Applicant: XDx, Inc.Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice, MacDonald Morris, Steven Rosenberg
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Publication number: 20100099098Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.Type: ApplicationFiled: August 19, 2009Publication date: April 22, 2010Applicant: XDX, INC.Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice, MacDonald Morris, Steven Rosenberg
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Patent number: 7691569Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.Type: GrantFiled: April 24, 2003Date of Patent: April 6, 2010Assignee: XDx, Inc.Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice, MacDonald Morris, Steven Rosenberg
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Patent number: 7235358Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.Type: GrantFiled: December 20, 2002Date of Patent: June 26, 2007Assignee: Expression Diagnostics, Inc.Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice
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Publication number: 20070037144Abstract: Leukocyte gene expression profiling is utilized to identify oligonucleotides from gene expression candidate libraries. The expression libraries are generally immobilized on an array. Diagnostic oligonucleotide sets for analysis of leukocyte-related diseases are described.Type: ApplicationFiled: October 22, 2001Publication date: February 15, 2007Inventors: Jay Wohlgemuth, Kirk Fry, George Matcuk, Peter Altman, James Prentice, Julie Phillips, Ngoc Ly, Robert Woodward, Thomas Quertermous, Frances Johnson
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Publication number: 20070031890Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.Type: ApplicationFiled: December 20, 2002Publication date: February 8, 2007Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice
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Publication number: 20060225422Abstract: Apparatus and processes are provided for combusting hydrocarbon-containing waste fuel with an oxidizer, preferably liquid oxygen, and producing a substantially clean exhaust gas and a separate high purity steam product (e.g., superheated steam) that can be used to generate electrical power. The apparatus includes a plurality of combustion chambers in series with means to control the combustion temperature while facilitating complete combustion. The apparatus and method are useful for transforming waste materials, particularly solid and liquid wastes, such as the rubber from scrap tires into non-hazardous materials and energy.Type: ApplicationFiled: June 16, 2006Publication date: October 12, 2006Applicant: ADVANCED COMBUSTION ENERGY SYSTEMS, INC.Inventor: James Prentice
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Publication number: 20060088836Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.Type: ApplicationFiled: April 24, 2003Publication date: April 27, 2006Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice, MacDonald Morris, Steven Rosenberg
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Publication number: 20060053791Abstract: The invention provides processes and apparatuses for safely, rapidly, cost-effectively and efficiently producing a superheated steam product or dry saturated steam product that can be employed to generate electrical power, or in other manufacturing and/or non-manufacturing processes, in an environmentally clean manner without causing corrosion to electrical power-generating devices. These processes and apparatuses involve the combustion of one or more fuels containing the elements hydrogen and/or carbon, which can be derived from waste materials, such as the rubber from scrap tires.Type: ApplicationFiled: December 16, 2003Publication date: March 16, 2006Applicant: Advanced Combustion Energy Systems, Inc.Inventor: James Prentice