Abstract: The present technology relates to methods for determining whether a patient diagnosed with breast cancer, colorectal cancer, melanoma or lung cancer will benefit from or is predicted to be responsive to treatment with an individual therapeutic agent or a specific combination of therapeutic agents. These methods are based on screening a patient's solid tumors and detecting alterations in target nucleic acid sequences corresponding to a specific set of cancer-related genes. Kits for use in practicing the methods are also provided.

Abstract: A method of estimating a property of an article manufactured, at least in part, by additive manufacturing, AM, preferably directed energy deposition, DED, and/or powder bed fusion, PBF, is described. The method implemented, at least in part, by a computer comprising a processor and a memory. The method comprises: obtaining a set of in-process parameters of the AM of the article, wherein respective parameters of the set thereof have positional information associated therewith; inferring a set of attributes of the article corresponding to the set of in-process parameters, wherein respective attributes of the set thereof have the positional information associated therewith; and estimating the property of the article based, at least in part, on the inferred set of attributes.

Abstract: Fastenerless and adhesiveless furniture pieces, which in various embodiments may include chairs, steps, adirondack chairs, footrests, and other furniture pieces, may each include a first panel, a second panel, and a plurality of support panels. The first and second panels may each one or more outwardly extending engagement members. The engagement members may each include a tapered void that mates with one of the support panels. The first and second panels may include curved edges that complement one another. The first panel, the second panel, and the plurality of support panels may be securely coupled to form the furniture piece, without relying on any fasteners or adhesives, when the complementary curved edges of the first and second panels are forced into abutting engagement with one another.

Abstract: The present technology relates to methods for determining whether a patient diagnosed with breast cancer, colorectal cancer, melanoma or lung cancer will benefit from or is predicted to be responsive to treatment with an individual therapeutic agent or a specific combination of therapeutic agents. These methods are based on screening a patient's solid tumors and detecting alterations in target nucleic acid sequences corresponding to a specific set of cancer-related genes. Kits for use in practicing the methods are also provided.

Abstract: A method and system for neuro-feedback training are disclosed. According to certain embodiments, the method may include receiving, by a processor via a communication network, a brainwave signal measured by at least one sensor attached to a user. The method may also include determining, by the processor, a frequency distribution of the brainwave signal. The method may also include determining, by the processor, a first value indicative of an amount of the brainwave signal within a first frequency band. The method may also include generating, by the processor based on the first value, a first control signal to actuate a target device wirelessly connected to the processor. The method may further include transmitting, by the processor via the communication network, the first control signal to the target device.

Abstract: Movable conveyor slats (12) have side parts (42, 44) which rest on top parts (32) of bearings (30). The bearings (30) have a generally U-shaped cross section and they fit on wings (16, 18) which extend outwardly and slope upwardly from the sides of a fixed conveyor slat (10). The movable slats (12) have web (48, 50) and lower flange portions (52, 54) which with the side parts (42, 44) form laterally outwardly opening channels. The wings (16, 18) and the bearings (30) are received within the channels (56, 58).

Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.

Abstract: The application discloses novel polymorphic crystalline forms of 2-[4-Bromo-3-(3-chloro-5-cyano-phenoxy)-2-fluoro-phenyl]-N-(2-chloro-4-propionylsulfamoyl-phenyl)-acetamide, sodium salt (Ib) with improved stability and physical properties which facilitate manufacturing, handling and formulating for treatment or prophylaxis of HIV mediated diseases, AIDS or ARC, in monotherapy or in combination therapy.

Abstract: A method of transferring information stored in a mobile instrument, the information including a first information file (140) containing metadata and a pointer indicative of a first auxiliary file address; and a first auxiliary file (141) containing image information, the first auxiliary file being located at the first auxiliary file address. The method includes the steps of: storing the metadata in a second information file (140?); storing the image information in a second auxiliary file (142?) at a second auxiliary file address; generating a second pointer indicative of the second auxiliary file address; and storing the second pointer in the second information file. The instrument includes a camera (70); one or more spatial sensors; and an external sensor port (56). Power to the sensors can be controlled asynchronously. Various parsing methods are also described. The instrument includes a marker module configured to superimpose a marker on the image.

Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.

Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.

Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.

Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.

Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.

Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.

Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.

Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.

Abstract: The application discloses novel polymorphic crystalline forms of 2-[4-Bromo-3-(3-chloro-5-cyano-phenoxy)-2-fluoro-phenyl]-N-(2-chloro-4-propionylsulfamoyl-phenyl)-acetamide, sodium salt (Ib) with improved stability and physical properties which facilitate manufacturing, handling and formulating for treatment or prophylaxis of HIV mediated diseases, AIDS or ARC, in monotherapy or in combination therapy.

Abstract: Movable conveyor slats (12) have side parts (42, 44) which rest on top parts (32) of bearings (30). The bearings (30) have a generally U-shaped cross section and they fit on wings (16, 18) which extend outwardly and slope upwardly from the sides of a fixed conveyor slat (10). The movable slats (12) have web (48, 50) and lower flange portions (52, 54) which with the side parts (42, 44) form laterally outwardly opening channels. The wings (16, 18) and the bearings (30) are received within the channels (56, 58).

Abstract: A method of transferring information stored in a mobile instrument, the information including a first information file containing metadata and a pointer indicative of a first auxiliary file address; and first auxiliary file containing image information, the first auxiliary file being located at the first auxiliary file address. The method includes the steps of: storing the metadata in a second information file; storing the image information in a second auxiliary file at a second auxiliary file address; generating a second pointer indicative of the second auxiliary file address; and storing the second pointer in the second information file. The instrument includes a camera; one or more spatial sensors; and an external sensor port. Power to the sensors can be controlled asynchronously. Various parsing methods are also described. The instrument includes a marker module configured to superimpose a marker on the image.