Patents by Inventor James Prentice

James Prentice has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240294989
    Abstract: The present technology relates to methods for determining whether a patient diagnosed with breast cancer, colorectal cancer, melanoma or lung cancer will benefit from or is predicted to be responsive to treatment with an individual therapeutic agent or a specific combination of therapeutic agents. These methods are based on screening a patient's solid tumors and detecting alterations in target nucleic acid sequences corresponding to a specific set of cancer-related genes. Kits for use in practicing the methods are also provided.
    Type: Application
    Filed: May 13, 2024
    Publication date: September 5, 2024
    Applicant: Quest Diagnostics Investments LLC
    Inventors: Heather SANDERS, Kevin QU, James PRENTICE, Frederic WALDMAN
  • Patent number: 11981966
    Abstract: The present technology relates to methods for determining whether a patient diagnosed with breast cancer, colorectal cancer, melanoma or lung cancer will benefit from or is predicted to be responsive to treatment with an individual therapeutic agent or a specific combination of therapeutic agents. These methods are based on screening a patient's solid tumors and detecting alterations in target nucleic acid sequences corresponding to a specific set of cancer-related genes. Kits for use in practicing the methods are also provided.
    Type: Grant
    Filed: May 8, 2020
    Date of Patent: May 14, 2024
    Assignee: Quest Diagnostics Investments LLC
    Inventors: Heather Sanders, Kevin Qu, James Prentice, Frederic Waldman
  • Publication number: 20200385817
    Abstract: The present technology relates to methods for determining whether a patient diagnosed with breast cancer, colorectal cancer, melanoma or lung cancer will benefit from or is predicted to be responsive to treatment with an individual therapeutic agent or a specific combination of therapeutic agents. These methods are based on screening a patient's solid tumors and detecting alterations in target nucleic acid sequences corresponding to a specific set of cancer-related genes. Kits for use in practicing the methods are also provided.
    Type: Application
    Filed: May 8, 2020
    Publication date: December 10, 2020
    Applicant: Quest Diagnostics Investments LLC
    Inventors: Heather Sanders, Kevin QU, James PRENTICE, Frederic WALDMAN
  • Patent number: 10689710
    Abstract: The present technology relates to methods for determining whether a patient diagnosed with breast cancer, colorectal cancer, melanoma or lung cancer will benefit from or is predicted to be responsive to treatment with an individual therapeutic agent or a specific combination of therapeutic agents. These methods are based on screening a patient's solid tumors and detecting alterations in target nucleic acid sequences corresponding to a specific set of cancer-related genes. Kits for use in practicing the methods are also provided.
    Type: Grant
    Filed: October 28, 2015
    Date of Patent: June 23, 2020
    Assignee: Quest Diagnostics Investments Incorporated
    Inventors: Heather Sanders, Kevin Qu, James Prentice, Frederic Waldman
  • Publication number: 20180142304
    Abstract: The present technology relates to methods for determining whether a patient diagnosed with breast cancer, colorectal cancer, melanoma or lung cancer will benefit from or is predicted to be responsive to treatment with an individual therapeutic agent or a specific combination of therapeutic agents. These methods are based on screening a patient's solid tumors and detecting alterations in target nucleic acid sequences corresponding to a specific set of cancer-related genes. Kits for use in practicing the methods are also provided.
    Type: Application
    Filed: October 28, 2015
    Publication date: May 24, 2018
    Applicant: Quest Diagnostics Investments Incorporated
    Inventors: Heather SANDERS, Kevin QU, James PRENTICE, Frederic WALDMAN
  • Publication number: 20110306518
    Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
    Type: Application
    Filed: August 22, 2011
    Publication date: December 15, 2011
    Applicant: XDx, Inc.
    Inventors: Jay WOHLGEMUTH, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice, MacDonald Morris, Steven Rosenberg
  • Publication number: 20110104697
    Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
    Type: Application
    Filed: January 5, 2011
    Publication date: May 5, 2011
    Applicant: XDx, Inc.
    Inventors: Jay WOHLGEMUTH, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice, MacDonald Morris, Steven Rosenberg
  • Patent number: 7892745
    Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
    Type: Grant
    Filed: September 8, 2009
    Date of Patent: February 22, 2011
    Assignee: XDx, Inc.
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice, MacDonald Morris, Steven Rosenberg
  • Patent number: 7879556
    Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
    Type: Grant
    Filed: August 12, 2010
    Date of Patent: February 1, 2011
    Assignee: XDx, Inc.
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice, MacDonald Morris, Steven Rosenberg
  • Publication number: 20100317018
    Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
    Type: Application
    Filed: August 12, 2010
    Publication date: December 16, 2010
    Applicant: XDx, Inc.
    Inventors: Jay WOHLGEMUTH, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice, MacDonald Morris, Steven Rosenberg
  • Patent number: 7785797
    Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
    Type: Grant
    Filed: August 19, 2009
    Date of Patent: August 31, 2010
    Assignee: XDx, Inc.
    Inventors: Jay Wohlgemuth, Kirk E. Fry, Robert Woodward, Ngoc Ly, James Prentice, Macdonald Morris, Steven Rosenberg
  • Publication number: 20100151467
    Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
    Type: Application
    Filed: September 8, 2009
    Publication date: June 17, 2010
    Applicant: XDx, Inc.
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice, MacDonald Morris, Steven Rosenberg
  • Publication number: 20100099098
    Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
    Type: Application
    Filed: August 19, 2009
    Publication date: April 22, 2010
    Applicant: XDX, INC.
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice, MacDonald Morris, Steven Rosenberg
  • Patent number: 7691569
    Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
    Type: Grant
    Filed: April 24, 2003
    Date of Patent: April 6, 2010
    Assignee: XDx, Inc.
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice, MacDonald Morris, Steven Rosenberg
  • Patent number: 7235358
    Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: June 26, 2007
    Assignee: Expression Diagnostics, Inc.
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice
  • Publication number: 20070037144
    Abstract: Leukocyte gene expression profiling is utilized to identify oligonucleotides from gene expression candidate libraries. The expression libraries are generally immobilized on an array. Diagnostic oligonucleotide sets for analysis of leukocyte-related diseases are described.
    Type: Application
    Filed: October 22, 2001
    Publication date: February 15, 2007
    Inventors: Jay Wohlgemuth, Kirk Fry, George Matcuk, Peter Altman, James Prentice, Julie Phillips, Ngoc Ly, Robert Woodward, Thomas Quertermous, Frances Johnson
  • Publication number: 20070031890
    Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
    Type: Application
    Filed: December 20, 2002
    Publication date: February 8, 2007
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice
  • Publication number: 20060225422
    Abstract: Apparatus and processes are provided for combusting hydrocarbon-containing waste fuel with an oxidizer, preferably liquid oxygen, and producing a substantially clean exhaust gas and a separate high purity steam product (e.g., superheated steam) that can be used to generate electrical power. The apparatus includes a plurality of combustion chambers in series with means to control the combustion temperature while facilitating complete combustion. The apparatus and method are useful for transforming waste materials, particularly solid and liquid wastes, such as the rubber from scrap tires into non-hazardous materials and energy.
    Type: Application
    Filed: June 16, 2006
    Publication date: October 12, 2006
    Applicant: ADVANCED COMBUSTION ENERGY SYSTEMS, INC.
    Inventor: James Prentice
  • Publication number: 20060088836
    Abstract: Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.
    Type: Application
    Filed: April 24, 2003
    Publication date: April 27, 2006
    Inventors: Jay Wohlgemuth, Kirk Fry, Robert Woodward, Ngoc Ly, James Prentice, MacDonald Morris, Steven Rosenberg
  • Publication number: 20060053791
    Abstract: The invention provides processes and apparatuses for safely, rapidly, cost-effectively and efficiently producing a superheated steam product or dry saturated steam product that can be employed to generate electrical power, or in other manufacturing and/or non-manufacturing processes, in an environmentally clean manner without causing corrosion to electrical power-generating devices. These processes and apparatuses involve the combustion of one or more fuels containing the elements hydrogen and/or carbon, which can be derived from waste materials, such as the rubber from scrap tires.
    Type: Application
    Filed: December 16, 2003
    Publication date: March 16, 2006
    Applicant: Advanced Combustion Energy Systems, Inc.
    Inventor: James Prentice