Abstract: A button for a drug delivery device with a reduced operating loudness includes a plate-like button body forming a touch surface, wherein the plate-like button body is coupled by an axial supporting member to a noise-generating interface of the drug delivery device and movable into a longitudinal direction of the drug delivery device, wherein the plate-like button body includes a material composite with at least one first component consisting of a first material and at least one second component consisting of a second material different from the first material, wherein the at least one first component and the at least one second component are coupled via at least one coupling plane that is at least sectionwise slanted or perpendicular to the longitudinal direction. Further, the disclosure describes a button assembly for a drug delivery device which is shock resistant.

Abstract: Disclosed are particles comprising polyalkylene glycol, an effervescent system and perfume for hard surface cleaning as well as a composition including these particles. Additionally, a method of making such particles and a method of using such particles for cleaning are also provided.

Abstract: Systems and methods for purposeful computing are disclosed that, among other things, include a user purpose class resource information computing environment. Such environment supports resource purpose classes, and further supports resource identification information sets that characterize their respective subject matter resources. The computing environment can be used to identify and evaluate one or more purpose class subject matter resource members.

Abstract: The present invention provides combination therapy that includes an KRASG12C inhibitor, such as or a pharmaceutically acceptable salt thereof, and one or more additional pharmaceutically active agents, particularly for the treatment of cancers. The invention also relates to pharmaceutical compositions that contain an KRASG12C inhibitor and one or more additional pharmaceutically active agents for the treatment of cancers.

Abstract: Dynamically generating data tests includes: receiving test templates and metadata for a plurality of data objects and, on a trigger condition: based on at least the metadata and the test templates, determining a current set of templated data tests, wherein determining the current set of templated data tests comprises: determining at least one templated data test, from a prior set of templated data tests, to cease using; determining at least one templated data test to add to the current set of templated data tests; and determining, within the current set of templated data tests, at least one templated data tests to regenerate; generating the at least one templated data test to add to the current set of templated data tests; regenerating the least one templated data test to regenerate; and executing templated data tests, within the set of current templated data tests, on the plurality of data objects.

Abstract: Implementations described herein relate to providing device messages in image compilations based on user content. A computer-implemented method includes determining that a playback mode is entered on a device to display one or more image compilations, each image compilation including images for successive display. Message criteria are obtained for device messages, each device message indicating a device function associated with images of the image compilations or of a user image library. A device message is selected based on associated message criteria. An image is identified in the user image library, the image being in the image compilations, depicts a type of image feature in the image compilations, and/or has characteristic(s) modifiable by the device function. The device message is displayed during image compilation playback and includes the identified image and a message control option. In response to user selection of the message control option, the device function is initiated.

Abstract: Methods and apparatus to communicate via a weld cable are disclosed. An example welding accessory includes a first port to receive input power via a first weld cable, a power converter to convert the input power to output power, a second port to output the input power via a second weld cable, and one or more output switches to selectively divert the input power from the power converter to the second port.

Abstract: Disclosed herein are compounds and compositions for nematode treatment. In particular, disclosed are compounds of formula (I), a method of treating a plant or a growing media for a nematode with compounds of formula (II), compositions, and methods of use.

Abstract: Spoolable tubing suitable for use in the oil industry, and more particularly spoolable composite tubing with the ability to withstand high stress and high cracking resistance.

Abstract: A vehicle head unit comprising a memory configured to store an operating system, and one or more processors may be configured to perform various aspects of the techniques. The one or more processors may obtain an indication of one or more vehicle networks, and execute the operating system that presents a single application programming interface that provides function calls by which to configure the one or more vehicle networks within the operating system. The one or more processors may also configure, via the single application programming interface, one or more network interfaces for the one or more vehicle networks in the operating system by which one or more applications, executing in an application space presented by the operating system, interface with the one or more vehicle networks.

Abstract: The present invention relates to new pyrrolopyridine compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of JAK1 and JAK3 kinase activity in a human or animal subject are also provided for the treatment diseases such as pruritus, alopecia, androgenetic alopecia, alopecia areata, vitiligo and psoriasis.

Abstract: A protective structure, to protect an antenna from damage, is provided. The protective structure includes a body. The body defines one or more prong-receiving apertures in a first surface of the body, wherein through each aperture of the one or more prong-receiving apertures, the body is configured to receive a prong of one or more prongs of the antenna. The body defines a radio frequency (RF) connection aperture extending from the first surface of the body to a second surface of the body, wherein the body is configured to receive a cable through the RF connection aperture to couple a cable connector of the cable to an RF connector of the antenna.

Abstract: An apparatus for supporting an array of layers of amphiphilic molecules, the apparatus comprising: a body, formed in a surface of the body, an array of sensor wells capable of supporting a layer of amphiphilic molecules across the sensor wells, the sensor wells each containing an electrode for connection to an electrical circuit, and formed in the surface of the body between the sensor wells, flow control wells capable of smoothing the flow of a fluid across the surface.

Abstract: The disclosure provides a nozzle adapted for placement within a flowpath of a turbomachine. The nozzle includes an airfoil having a suction side; a pressure side opposing the suction side; a leading edge between the pressure side and the suction side; a trailing edge opposing the leading edge and between the pressure side and the suction side; a root region at a first radial end; a tip region at a second radial end opposite the first radial end; and a midspan region between the root region and the tip region. An endwall is connected with the root region or the tip region of the airfoil along the suction side, the pressure side, the trailing edge, and the leading edge. The trailing edge of the airfoil has an elliptical shape having a nominal profile substantially in accordance with Cartesian coordinate values of X, Y, and Z set forth in TABLE I.

Abstract: An event query host can include an event processor configured to process an event stream indicating events that occurred on a computing device. The event processor can add representations of events to an event graph. If an event added to the event graph is a trigger event associated with a query, the event processor can also add an instance of the query to a query queue. The query queue can be sorted based on scheduled execution times of query instances. At a scheduled execution time of a query instance in the query queue, a query manager of the event query host can execute the query instance and attempt to find a corresponding pattern of one or more events in the event graph.

Abstract: A seat assembly includes a seatback having an interior portion with a seatback frame disposed therein. A retraction mechanism includes a first bracket operably coupled to the seatback frame. A second bracket is operably coupled to the first bracket by an actuator that is operable between at-rest and actuated positions. A tether member includes a body portion that is operably coupled between the first and second brackets of the retraction mechanism for movement therewith. The tether member moves from a deployed position to a retracted position when the actuator moves from the at-rest position to the actuated position. A belt member is operably coupled to the tether member. The belt member is operable between a deployed position, wherein the belt member is disposed in front of the back support portion of the seatback, and a stowed position, wherein the belt member is received in the interior portion of the seatback.

Abstract: Systems and methods for generating min-increment counting bloom filters to determine count and frequency of device identifiers and attributes in a networking environment are disclosed. The system can maintain a set of data records including device identifiers and attributes associated with device in a network. The system can generate a vector comprising coordinates corresponding to counter registers. The system can identify hash functions to update a counting bloom filter. The system can hash the data records to extract index values pointing to a set of counter registers. The system can increment the positions in the min-increment counting bloom filter corresponding to the minimum values of the counter registers. The system can obtain an aggregated public key comprising a public key. The system can encrypt the counter registers using the aggregated shared key to generate an encrypted vector. The system can transmit the encrypted vector to a networked worker computing device.

Abstract: A tissue marking device enables the deployment of a hook to mark a location within a breast. The deployment is performed by inserting a needle in tissue until it arrives at a target location and pressing on the end of a rod that embeds the hook in the tissue. A thread is attached to the hook and is left exposed to facilitate locating the hook.

Abstract: An indexed sequence of bits in a buffer is allocated for tracking a battery charging state. The indexed sequence of bits has a first number of bits. A battery voltage of a rechargeable battery is sampled at a sampling rate. For each sampled battery voltage, the battery voltage is compared with a voltage threshold. A next bit position in the indexed sequence of bits is identified. In accordance with a determination that a comparison result is true, a predefined first value is added to the next bit position. A second number of bits that are filled with the predefined first value is determined. A ratio between the second number and the first number is also determined. In accordance with a determination that the ratio exceeds a threshold step-down ratio, a battery charge voltage is stepped down. The rechargeable battery is charged to a step-down voltage.

Abstract: A system for generating a cement composition comprising: a plurality of cementitious components; and a computer system configured to accept input from a user and generate concentrations of the cementitious components for the cement composition, wherein the computer system is configured to generate the concentrations of the cementitious components based on a target lime to silica correlation.