Abstract: A computer-implemented method of controlling the operation of a robotic vacuum cleaner that includes the steps of: receiving dust distribution data indicating the spatial distribution of dust particles across the floor of a building; and planning a cleaning operation of the floor of the building to be executed by the robotic vacuum cleaner, based on the received dust distribution data. Additional computer-implemented methods relate to planning a cleaning operation manually via a client device, and an alert generation method based on dust distribution data.

Abstract: An audio cancellation system includes a voice enabled computing system that is connected to an audio output device using a wired or wireless communication network. The voice enabled computing device can provide media content to a user and receive a voice command from the user. The connection between the voice enabled computing system and the audio output device introduces a time delay between the media content being generated at the voice enabled computing device and the media content being reproduced at the audio output device. The system operates to determine a calibration value adapted for the voice enabled computing system and the audio output device. The system uses the calibration value to filter the user's voice command from a recording of ambient sound including the media content, without requiring significant use of memory and computing resources.

Abstract: Cancer immunology provides promising new avenues for cancer treatment but validation of potential neoantigens to target is costly and expensive. Analysis of MHC binding affinity, antigen processing, similarity to known antigens, predicted expression levels (as mRNA or proteins), self-similarity, and mutant allele frequency, provides screening method to identify and prioritize candidate neoantigens using sequencing data. Methods of the invention thereby save time and money by identifying the priority candidate neoantigens for further experimental validation.

Abstract: The present disclosure provides binding agents, such as antibodies, that specifically bind LAIR-1, including human LAIR-1, as well as compositions comprising the binding agents, and methods of their use. The disclosure also provides related polynucleotides and vectors encoding the binding agents and cells comprising the binding agents.

Abstract: A method of manufacturing a tower structure includes printing and depositing, via a printhead assembly of an additive printing system, one or more printed layers of a wall of the tower structure. The method also includes unwinding at least one continuous roll of a reinforcement material to form at least one continuous reinforcement ring member layer, the reinforcement material comprising a pultruded polymer material. Further, the method includes placing the at least one continuous reinforcement ring member layer atop the one or more printed layers of the wall of the tower structure. Moreover, the method includes printing and depositing, via the printhead assembly of the additive printing system, one or more additional printed layers of the wall of the tower structure atop the at least one continuous reinforcement ring member layer.

Abstract: A content management system may instantiate, from the same super class defined in a database schema, principal objects representing users and groups and content objects representing documents and folders. The principal objects and the content objects share the same social interaction functions. When a content object is modified, the system can create a message in which the content object identifies itself as a first person, update a message table such that any follower of the content object is notified of the message, and update a profile or feed associated with the content object. At least because content objects can “socialize” like principal objects, the system can generate a social graph containing content objects as nodes, map relationships among principal objects and content objects, and make recommendations to perhaps change/enhance such relationships.

Abstract: A seat assembly includes a seat portion having a frame assembly, a carrier assembly and a displaceable platform operably coupled to the carrier assembly. The displaceable platform is operable between a use position and a deployed position. A retraction mechanism includes a first bracket operably coupled to the frame assembly, and a second bracket operably coupled to the displaceable platform. The first and second brackets are interconnected by an actuator that is operable between at-rest and actuated positions. The second bracket moves from a first position to a second position as the actuator moves from the at-rest position to the actuated position. At least one tether member is operably coupled to the first bracket and includes a body portion interlaced between the first and second brackets of the retraction mechanism.

Abstract: The present document describes systems and techniques for battery management and optimization using voice integration systems. These techniques include one or more electronic devices defining a voice integration system and having connectivity to a server system. These devices are configured to provide audio data relating to battery operations, including battery charging, to a user of an electronic device. Further, these techniques enable the user of the electronic device to provide additional audio data to the voice integration system and, thereby, instruct the server system to perform one or more actions relating to battery operations associated with the electronic device. In this way, the user can manage and optimize battery operations using the voice integration system.

Abstract: Filters for surgical procedures including a fluid pathway to transport fluid, such as smoke and/or gases, exhausted from a surgical site, a humidity regulating element located along the fluid pathway, and a filter element located downstream of the humidity regulating element such that the humidity regulating element and the filter element are in fluid communication with each other. The humidity regulating element is configured to remove or reduce humidity from the smoke and/or gases exhausted from the surgical site prior to the smoke and/or gases reaching the filter element. The filter element is configured to filter particulate matter from the smoke and/or gases exhausted from the surgical site.

Abstract: Disclosed herein are arylpyridinone compounds and compositions useful in the treatment of ITK mediated diseases, such as inflammation, having the structures of Formulas (I)-(IV): wherein the R groups, m, n, and X are as defined in the detailed description. Methods of inhibition of ITK activity in a human or animal subject are also provided.

Abstract: A hybrid-electric powerplant (HEP) of an aircraft comprises a thermal engine providing a first torque input to the HEP and an electric motor providing a second torque input to the HEP. A power management system connected to one or both of the thermal engine and the electric motor comprises an engine control unit (ECU) connected to the thermal engine. The ECU controls fuel supplied to the thermal engine. An electric propulsion control (EPC) is connected to the electric motor and controls power supplied to the electric motor. The EPC includes an EPC protection module in communication with a power source for the electric motor. The EPC protection module disables power supplied to the electric motor upon receipt of a signal indicative of one or more of an over-speed condition and an over-torque condition detected in the HEP.

Abstract: Disclosed herein are systems, devices, and methods for a wall system, the wall system comprising: one or more wall panels, each defining at least one connecting feature defined in at least one perimeter of the wall panel, each connecting feature configured to connect an adjacent wall panel; and at least one of the one or more wall panels comprising one or more features arranged in a framing layout, the one or more features configured for engagement with at least one framing member.

Abstract: An adjustable bed frame is disclosed herein. The adjustable bed frame includes a plurality of support beams and a plurality of slats arranged perpendicularly over the plurality of support beams to define a support surface for a mattress. A width of the adjustable bed frame is adjustable by adjusting a position of the plurality of support beams relative to each other in a parallel direction, thereby enabling the adjustable bed frame to quickly and easily transform between a twin-sized bed, a double-sized bed, a queen-sized bed and/or a king-sized bed.

Abstract: An assembly for display and storage, includes a main body with a top surface configured to present items, a bottom surface, and three side surfaces that define an internal cavity. The top surface may include at least one extendable platform that can transition between a stored position coplanar with the top surface and an open position extending laterally. Within the cavity, at least one height-adjustable shelf may be provided. The assembly may include a support that extends vertically from the main body, holding an adjustable signage assembly, which may be digital and remotely updatable.

Abstract: Technologies are disclosed for contingency vehicular signaling. A first DC power source may be connected with one or more indicators. The first DC power source may be connected with a second DC power source, and/or a third DC power source, via a semiconductor. The first DC power source may be configured to receive a second DC current flow from the second DC power source, and/or a third DC current flow from the third DC power source. The semiconductor may be configured to block a first DC current flow from the first DC power source to the second DC power source, and/or the third DC power source. The first DC power source may be configured to provide the one or more indicators with the first DC current flow via the at least one electrical switch regardless of a magnitude of the second DC current flow, and/or the third DC current flow.

Abstract: A milk frother comprises a housing, a motor, a power supply, two rods, and two aerating members. The motor is located within the housing, with the motor comprising a rotatable shaft. The power supply is located within the housing, with the power supply configured to supply electrical power to the motor to effect rotation of the shaft. The two rods extend through the housing, with each of the rods comprising first and second ends. Each of the rods are operably coupled to the shaft proximate to the first ends, and rotation of the shaft effects rotation of the rods. Each of the aerating members is connected to one of the two rods proximate to the second ends. Rotation of the rods effects rotation of the aerating members to produce froth when the aerating members are placed within the milk.

Abstract: Systems and methods are disclosed for using a pressure relief shipping adapter to reduce the internal pressure of a container. A pressure relief shipping adapter includes a body comprising a first portion, a transitional portion, and a second portion. The first portion comprises a set of protrusions and a hole disposed through the set of protrusions. The second portion comprises an outlet disposed at a second end of the body. The outlet is concentric with an inlet disposed at the first end of the body. The transitional section is disposed between the first portion and the second portion. The pressure relief shipping adapter also includes an internal chamber within the body.

Abstract: Methods and systems are provided for a multi-fuel engine. In one example, a method includes operating engines of rail vehicles at a desired substitution ratio to recharge an energy storage device of a rail vehicle operating in an all-electric mode to meet a requested total power.

Abstract: The present invention relates to new pyrrolopyridine compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of JAK1 and JAK3 kinase activity in a human or animal subject are also provided for the treatment diseases such as pruritus, alopecia, androgenetic alopecia, alopecia areata, vitiligo and psoriasis.

Abstract: Embodiments are disclosed for a generating graph representations of neural networks to be used as input for one or more metanetworks. Architectural information can be extracted from a neural network and used to generate graph a representation. A subgraph can be generated for each layer of the neural network, where each subgraph includes nodes that correspond to neurons and connecting edges that correspond to weights. Each layer of the neural network can be associated with a bias node that is connected to individual nodes of that layer using edges representing bias weights. Various types of neural networks and layers of neural networks can be represented by such graphs, which are then used as inputs for metanetworks. The subgraphs can be combined into a comprehensive graph representation of the neural network, which can be provided as input to a metanetwork to generate network parameters or perform another such operation.