Patents by Inventor James Rolke

James Rolke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified pectins, compositions and methods related thereto
    Patent number: 8420133
    Abstract: The present invention provides compositions of modified pectin and methods for preparing and using them.
    Type: Grant
    Filed: August 17, 2012
    Date of Patent: April 16, 2013
    Assignee: La Jolla Pharmaceutical Company
    Inventors: Mark Staples, James Rolke
  • Modified pectins, compositions and methods related thereto
    Patent number: 8409635
    Abstract: The present invention provides compositions of modified pectin and methods for preparing and using them.
    Type: Grant
    Filed: August 17, 2012
    Date of Patent: April 2, 2013
    Assignee: La Jolla Pharmaceutical Company
    Inventors: Mark Staples, James Rolke
  • MODIFIED PECTINS, COMPOSITIONS AND METHODS RELATED THERETO
    Publication number: 20120315309
    Abstract: The present invention provides compositions of modified pectin and methods for preparing and using them.
    Type: Application
    Filed: August 17, 2012
    Publication date: December 13, 2012
    Applicant: La Jolla Pharmaceutical Company
    Inventors: Mark Staples, James Rolke
  • MODIFIED PECTINS, COMPOSITIONS AND METHODS RELATED THERETO
    Publication number: 20120309711
    Abstract: The present invention provides compositions of modified pectin and methods for preparing and using them.
    Type: Application
    Filed: August 17, 2012
    Publication date: December 6, 2012
    Applicant: La Jolla Pharmaceutical Company
    Inventors: Mark Staples, James Rolke
  • MODIFIED PECTINS, COMPOSITIONS AND METHODS RELATED THERETO
    Publication number: 20120149658
    Abstract: The present invention provides compositions of modified pectin and methods for preparing and using them.
    Type: Application
    Filed: February 17, 2012
    Publication date: June 14, 2012
    Applicant: La Jolla Pharmaceuticals Company
    Inventors: Mark Staples, James Rolke
  • Modified pectins, compositions and methods related thereto
    Patent number: 8187642
    Abstract: The present invention provides compositions of modified pectin and methods for preparing and using them.
    Type: Grant
    Filed: January 24, 2012
    Date of Patent: May 29, 2012
    Assignee: La Jolla Pharmaceutical Company
    Inventors: Mark Staples, James Rolke
  • MODIFIED PECTINS, COMPOSITIONS AND METHODS RELATED THERETO
    Publication number: 20120123102
    Abstract: The present invention provides compositions of modified pectin and methods for preparing and using them.
    Type: Application
    Filed: January 24, 2012
    Publication date: May 17, 2012
    Applicant: La Jolla Pharmaceutical Company
    Inventors: Mark Staples, James Rolke
  • Modified pectins, compositions and methods related thereto
    Patent number: 8128966
    Abstract: The present invention provides compositions of modified pectin and for preparing and using them.
    Type: Grant
    Filed: March 28, 2005
    Date of Patent: March 6, 2012
    Assignee: La Jolla Pharmaceutical Company
    Inventors: Mark Staples, James Rolke
  • PHARMACEUTICAL FORMULATIONS OF BIODEGRADABLE BIOCOMPATIBLE CAMPTOTHECIN-POLYMER CONJUGATES
    Publication number: 20100179181
    Abstract: A camptothecin/polymer dual phase drug release system is described that is stable in both liquid and lyophilized states. The polymer contains acetals and/or ketals.
    Type: Application
    Filed: December 10, 2009
    Publication date: July 15, 2010
    Applicant: Mersana Therapeutics, Inc.
    Inventors: James ROLKE, Russell C. PETTER, Mao YIN, Aleksandr YURKOVETSKIY, Gui LIU, Emile FARHAN
  • Glucan preparations
    Publication number: 20080103112
    Abstract: Particulate ?-glucan is solubilized at elevated pressure and temperature to form soluble ?-glucan. The method is safe and economical and produces a product that is an improved pharmaceutical agent.
    Type: Application
    Filed: June 15, 2007
    Publication date: May 1, 2008
    Inventors: Andrew Magee, James Rolke, Ren-der Yang
  • Modified pectins, compositions and methods related thereto
    Publication number: 20050250735
    Abstract: The present invention provides compositions of modified pectin and for preparing and using them.
    Type: Application
    Filed: March 28, 2005
    Publication date: November 10, 2005
    Applicant: GlycoGenesys, Inc.
    Inventors: Mark Staples, James Rolke
  • Methods for controlling the viscosity of polymer-based tissue sealants and adhesives
    Publication number: 20050079999
    Abstract: The invention provides methods and compositions that are useful for adhering biological and/or synthetic tissues, sealing fluid and/or gaseous leaks in biological and/or synthetic tissues, and preparing implants useful for delivery of a bioactive molecule such as a drug, for bulking applications, or for tissue prostheses. The present invention also relates to bio-erodable adhesive or occluding compositions and methods of using the same.
    Type: Application
    Filed: September 30, 2003
    Publication date: April 14, 2005
    Inventors: James Wilkie, James Rolke, Luis Burzio, Shekharam Tammishetti, Sanyog Pendharkar, Eugene Pashkovski
  • Methods and compositions for sealing tissue leaks
    Publication number: 20050037960
    Abstract: The invention provides methods and compositions that are useful for adhering biological and/or synthetic tissues, sealing fluid and/or gaseous leaks in biological and/or synthetic tissues, and preparing implants useful for delivery of a bioactive molecule such as a drug, for bulking applications, or for tissue prostheses. The present invention also relates to bio-erodable adhesive or occluding compositions and methods of using the same.
    Type: Application
    Filed: September 30, 2003
    Publication date: February 17, 2005
    Inventors: James Rolke, Luis Burzio
  • Primers for use with tissue sealants and adhesives and methods for using the same
    Publication number: 20040072756
    Abstract: The invention provides methods and compositions that are useful for adhering biological and/or synthetic tissues, sealing fluid and/or gaseous leaks in biological and/or synthetic tissues, and preparing implants useful for delivery of a bioactive molecule such as a drug, for bulking applications, or for tissue prostheses. The present invention also relates to bio-erodable adhesive or occluding compositions and methods of using the same.
    Type: Application
    Filed: September 30, 2003
    Publication date: April 15, 2004
    Inventors: James Wilkie, James Rolke, Luis Burzio, Shekharam Tammishetti, Sanyog Manohar Pendharkar, Eugene Pashkovski
  • Methods and compositions for sealing tissue leaks
    Publication number: 20040063613
    Abstract: The invention provides methods and compositions that are useful for adhering biological and/or synthetic tissues, sealing fluid and/or gaseous leaks in biological and/or synthetic tissues, and preparing implants useful for delivery of a bioactive molecule such as a drug, for bulking applications, or for tissue prostheses. The present invention also relates to bio-erodable adhesive or occluding compositions and methods of using the same.
    Type: Application
    Filed: September 30, 2003
    Publication date: April 1, 2004
    Inventors: James Rolke, Luis Burzio, Eugene Pashkovski
  • Mixing device for surgical sealants, and method thereof
    Publication number: 20030225378
    Abstract: What is described herein is a mixing device having a plurality of chambers and at least one transferor for mixing components of a tissue sealant.
    Type: Application
    Filed: April 25, 2003
    Publication date: December 4, 2003
    Applicant: Surgical Sealants, Inc.
    Inventors: James Wilkie, James Rolke, Luis Burzio, Gary Ayotte
  • Methods and compositions for sealing tissue leaks
    Publication number: 20020022588
    Abstract: The invention provides methods and compositions that are useful for adhering biological and/or synthetic tissues, sealing fluid and/or gaseous leaks in biological and/or synthetic tissues, and preparing implants useful for delivery of a bioactive molecule such as a drug, for bulking applications, or for tissue prostheses. The present invention also relates to bio-erodable adhesive or occluding compositions and methods of using the same.
    Type: Application
    Filed: December 22, 2000
    Publication date: February 21, 2002
    Inventors: James Wilkie, James Rolke, Luis Burzio, Shekharam Tammishetti, Sanyog Manohar Pendharkar