Abstract: A kinetic sleep apparatus that utilizes kinetic energy (vibration) and sound to facilitate relaxation and sleep by a user. The apparatus comprises an amplifier and at least one transducer that can be placed under a mattress, pillow, or seat cushion. A customized audio file is provided which will generate vibration frequencies to simulate the vibrations an individual would experience with an automobile, airplane, cruise ship or even other transportation modes. Each customized audio file includes several other layers in addition to the vibration frequencies, including brain wave frequencies, and natural calming sounds such as rain, ocean waves, wind, didgeridoo, a rainforest, and other soothing sounds of nature.

Abstract: This invention relates to novel compounds and pharmaceutical compositions comprising the novel compounds. More specifically, the invention relates to compounds useful as inhibitors of discoidin domain receptor 1 (DDR1) and discoidin domain receptor 2 (DDR2). The compounds are particularly useful in the treatment of cancer and fibrotic diseases.

Abstract: Methods and systems for a device connectivity services system. A method for using the device connectivity services includes receiving a request to connect with a device to perform one or more tasks at the device, processing the request with respect to connectivity factors related to the request and the device, scheduling the request based on the connectivity factors, instantiating a controller to execute the one or more tasks at the device, sending commands to the device over a connection to perform the one or more tasks, and receiving responses from the device over the connection after completing the one or more tasks.

Abstract: A quality of service management system includes a rules engine that receives information associated with a communication path having an assigned quality of service (QoS) to be provided for a customer communication device, and identifies one or more network elements assigned to provide the communication path. Each network element having a plurality of queues configured to provide varying QoS levels relative to one another. For each of the network elements, the rules engine determines at least one queue that is configured to provide the communication path at the assigned quality of service, and transmits queue information associated with the determined queue to its respective network element, the network element conveying the communication path through the determined queue.

Abstract: Methods and systems for a device connectivity services system. A method for using the device connectivity services includes receiving a request to connect with a device to perform one or more tasks at the device, processing the request with respect to connectivity factors related to the request and the device, scheduling the request based on the connectivity factors, instantiating a controller to execute the one or more tasks at the device, sending commands to the device over a connection to perform the one or more tasks, and receiving responses from the device over the connection after completing the one or more tasks.

Abstract: A beverage dispense apparatus and associated method, comprises a frame (11) for removably locating and holding a sealed beverage unit package (C) in a vertical orientation. A first piercing element (14) punctures a vent opening into a headspace of the beverage package (C) and, subsequently as the first piercing element is driven downward, a second piercing element (15) punctures an outlet opening into the beverage package so that beverage can flow through a nozzle (17) under gravity. An ultrasonic transducer (16) against the nozzle (17) may supply excitation energy that breaks gas out of solution so that a creamy head is formed on the beverage in a delivery vessel underneath the frame. Control of the vent opening/vale (13) enables flow to be slowed or stopped through the nozzle (17) enabling a settle time and “two-part” pour.

Abstract: A quality of service management system includes a rules engine that receives information associated with a communication path having an assigned quality of service (QoS) to be provided for a customer communication device, and identifies one or more network elements assigned to provide the communication path. Each network element having a plurality of queues configured to provide varying QoS levels relative to one another. For each of the network elements, the rules engine determines at least one queue that is configured to provide the communication path at the assigned quality of service, and transmits queue information associated with the determined queue to its respective network element, the network element conveying the communication path through the determined queue.

Abstract: This invention relates to compounds that may be useful for inhibiting RAS proteins. More specifically, this invention relates to compounds for inhibiting a broad spectrum of KRAS mutant proteins. The compounds of the invention may therefore be used in treating conditions mediated by KRAS proteins. For example, the compounds may be used in treating cancer.

Abstract: Methods and systems for a device connectivity services system. A method for using the device connectivity services includes receiving a request to connect with a device to perform one or more tasks at the device, processing the request with respect to connectivity factors related to the request and the device, scheduling the request based on the connectivity factors, instantiating a controller to execute the one or more tasks at the device, sending commands to the device over a connection to perform the one or more tasks, and receiving responses from the device over the connection after completing the one or more tasks.

Abstract: A quality of service management system includes a rules engine that receives information associated with a communication path having an assigned quality of service (QoS) to be provided for a customer communication device, and identifies one or more network elements assigned to provide the communication path. Each network element having a plurality of queues configured to provide varying QoS levels relative to one another. For each of the network elements, the rules engine determines at least one queue that is configured to provide the communication path at the assigned quality of service, and transmits queue information associated with the determined queue to its respective network element, the network element conveying the communication path through the determined queue.

Abstract: A pouring attachment device for a disposable package of nitrogenated beverage, e.g. an aluminium can P, that achieves a desirable foam head when the beverage is poured into a glass. The attachment comprises a main body or housing (11), an ultrasonic wave generator (27) and a means to couple the device to the package, such as a rim seal (2)0. A flow channel has a contoured inlet (26) configured for communicating beverage from the package to an outlet (21), via a resonance chamber (28), and is particularly configured for minimising turbulence.

Abstract: A quality of service management system includes a rules engine that receives information associated with a communication path having an assigned quality of service (QoS) to be provided for a customer communication device, and identifies one or more network elements assigned to provide the communication path. Each network element having a plurality of queues configured to provide varying QoS levels relative to one another. For each of the network elements, the rules engine determines at least one queue that is configured to provide the communication path at the assigned quality of service, and transmits queue information associated with the determined queue to its respective network element, the network element conveying the communication path through the determined queue.

Abstract: A method for identifying VLANs associated with a network includes gathering actual network element configuration data from a plurality of network elements in the network, wherein the actual network element configuration data identifies one or more VLANs that at least some of the plurality of network elements are actually allocated to; correlating the actual network element configuration data with administrative VLAN data; and determining one or more VLANs that are not commonly identified in both the actual network element configuration data and the administrative VLAN data.

Abstract: A method for identifying VLANs associated with a network includes gathering actual network element configuration data from a plurality of network elements in the network, wherein the actual network element configuration data identifies one or more VLANs that at least some of the plurality of network elements are actually allocated to; correlating the actual network element configuration data with administrative VLAN data; and determining one or more VLANs that are not commonly identified in both the actual network element configuration data and the administrative VLAN data.

Abstract: A quality of service management system includes a rules engine that receives information associated with a communication path having an assigned quality of service (QoS) to be provided for a customer communication device, and identifies one or more network elements assigned to provide the communication path. Each network element having a plurality of queues configured to provide varying QoS levels relative to one another. For each of the network elements, the rules engine determines at least one queue that is configured to provide the communication path at the assigned quality of service, and transmits queue information associated with the determined queue to its respective network element, the network element conveying the communication path through the determined queue.

Abstract: A quality of service management system includes a rules engine that receives information associated with a communication path having an assigned quality of service (QoS) to be provided for a customer communication device, and identifies one or more network elements assigned to provide the communication path. Each network element having a plurality of queues configured to provide varying QoS levels relative to one another. For each of the network elements, the rules engine determines at least one queue that is configured to provide the communication path at the assigned quality of service, and transmits queue information associated with the determined queue to its respective network element, the network element conveying the communication path through the determined queue.

Abstract: An apparatus (10) and method for dispensing beverage from a single serve beverage package (b), e.g. an aluminium can B. In operation the sealed package (B) is located and held in a receiving enclosure (11) where, firstly, a dispense end of the package is opened by a piercing element (24) and, secondly, a gas is introduced under pressure at a second end through a hollow needle (19). Gas from a pump, into the internal volume of package (B), is then used to drive beverage from the beverage package, e.g. through a restrictor structure (27), at the dispense end and into a drinking vessel (G). The pump mode may then apply negative pressure to prevent flow and enable a pause in flow or at completion of delivery to a vessel (G).

Abstract: A portable universal monitoring device according to various aspects of the present technology includes a portable body housing a plurality of sensor devices. The portable body is configured to be repeatedly attached to and detached from one or more objects such as a wristwatch. The portable body is configured to be discretely positioned on the object to remain unseen without negatively affecting the fit, function, operation, or comfort of the object during use. The portable body may be used interchangeably with any number of objects without requiring the objects themselves to be modified.