Abstract: In an apparatus and related method, a substrate that has multiple facets is held in a chamber of a plasma reactor that has multiple plasma cavities. The substrate is positioned by a transport arrangement with each plasma cavity of the plasma reactor aligned to a facet of the substrate. A plasma is generated in each plasma cavity, to apply simultaneous plasma processing to multiple facets of the substrate.

Abstract: The present invention provides, among other things, methods and compositions for treating primary ciliary dyskinesia (PCD) based on mRNA therapy. The present invention is based, in part, on the surprising discovery that administration of the mRNA encoding a DNAI1 protein at a dose ranging from 1 mg to 36 mg daily for five consecutive days resulted in restoration of ciliary function in PCD. Additionally, the methods of the present invention resulted in expression of the DNAI1 protein in airway epithelium at a level at least 10% of the wild-type level, an increase ciliary beat frequency (CBF), and DNAI1-positive transfection efficiency of greater than 5% in ciliated cells.

Abstract: The invention improves holographic imaging systems by being modular with deployment in a lens-less configuration or with a microscope objective, leading to a resolution range of 5.5 and to 0.5 ?m/pixel, respectively, and resulting in a resolvable particle size range of several microns to a few cm between two setups. The invention includes variable sampling length between two windows (e.g., a sampling volume of 71.4 mL per hologram at 12 cm). Holograms are recorded with a 4920×3280 pixels digital camera. i.e., 15.3 MB per image, at a maximum rate of 3.2 Hz, such that free stream water sampling a 14 L/minute occurs. This is orders of magnitude higher than sampling of other imaging systems while including larger/variable sample volume, inclusion of copper shutters to prevent biofouling during long-term deployments, including deployment in different operation modes. No single previous system achieves all these things at the same time.

Abstract: A purchasing permission utilizing a non-fungible token system includes a method of securely transferring a good comprising the steps of providing a physical product and creating a non-fungible token (NFT) associated with the physical product. The NFT is transferred to a prospective buyer of the physical product and the identification information of the prospective buyer is recorded in a blockchain which contains the NFT. The physical product is offered for sale on a digital platform the prospective buyer is allowed to purchase the physical product by validation of the NFT's association with the physical product.

Abstract: Provided herein are compositions and methods for assaying target proteins on extracellular vesicles in plasma. In some methods, the responsiveness of a subject to immunotherapy is determined.

Abstract: A system provides for strobing or high conspicuity signaling with vehicle hazard and other lights depending upon inputs and parameters.

Abstract: A system provides for strobing or high conspicuity signaling with vehicle hazard and other lights depending upon inputs and parameters.

Abstract: Bi-directional communication, through a computing system, may be used to maintain and monitor regulatory compliance. Employees of a firm may be prompted to provide information, which may be communicated to the computing system and stored in one or more databases. An internal auditor may be provided with a user interface that permits the initiation of audits, viewing of information reported, and/or the opportunity to provide findings and/or comments based on the information reported. The information reported may be provided to the auditor in the form of predetermined types of reports, based on the information reported.

Abstract: The present disclosure relates to methods of identifying a cancer having sensitivity to an ATR inhibitor compound, and treating subjects with such identified cancers with the ATR inhibitor, particularly in combination with a DNA damaging agent.

Abstract: A magnesium component of a rotary wing aircraft is provided including a groove including a first sidewall and a second sidewall arranged on opposing sides of a recessed opening. The first sidewall includes a deposit positioned adjacent the recessed opening. The deposit is formed by cold spraying one or more layers or powdered material within an area of the first sidewall from which material was removed.

Abstract: An infusion set system includes a base and a fluid connector removably coupleable thereto. The fluid connector includes a fluid path portion and at least one connector latch displaceably connected to the fluid path portion and displaceable to a latching position in which at least a portion of the connector latch extends into the fluid path portion, which includes a cannula extending from a top interior surface thereof, and a plurality of internal sidewalls corresponding to at least two of a plurality of flat side surfaces of at least one of a base section and a base latch, thereby facilitating connection between the base and the fluid connector in a plurality of discrete rotational connecting positions. When the fluid connector is locked to the base, the at least one connector latch engages a base latching portion of the base and restricts proximal displacement of the fluid connector.

Abstract: Methods, apparatus, systems and articles of manufacture are disclosed to assess compliance of a virtual computing environment. An example method disclosed herein to assess compliance of computing resources of a computing environment includes monitoring for an occurrence of a change in a computing resource in the computing environment, and in response to detecting the occurrence and without waiting for batch testing, assessing compliance of the computing resource with a compliance policy.

Abstract: An infusion set system includes a base and a fluid connector removably coupleable thereto. The fluid connector includes a fluid path portion and at least one connector latch displaceably connected to the fluid path portion and displaceable to a latching position in which at least a portion of the connector latch extends into the fluid path portion, which includes a cannula extending from a top interior surface thereof, and a plurality of internal sidewalls corresponding to at least two of a plurality of flat side surfaces of at least one of a base section and a base latch, thereby facilitating connection between the base and the fluid connector in a plurality of discrete rotational connecting positions. When the fluid connector is locked to the base, the at least one connector latch engages a base latching portion of the base and restricts proximal displacement of the fluid connector.

Abstract: An infusion set system includes a base and a fluid connector removably coupleable thereto. The fluid connector includes a fluid path portion and at least one connector latch displaceably connected to the fluid path portion and displaceable to a latching position in which at least a portion of the connector latch extends into the fluid path portion, which includes a cannula extending from a top interior surface thereof, and a plurality of internal sidewalls corresponding to at least two of a plurality of flat side surfaces of at least one of a base section and a base latch, thereby facilitating connection between the base and the fluid connector in a plurality of discrete rotational connecting positions. When the fluid connector is locked to the base, the at least one connector latch engages a base latching portion of the base and restricts proximal displacement of the fluid connector.

Abstract: Various embodiments of a livestock grooming article and method of forming same are disclosed. The livestock grooming article includes a handle extending along a handle axis, and a head extending along a head axis and connected to the handle. The head includes a body including a first major surface and a second major surface, and a back slidably connected to the first major surface of the body. The back includes a first major surface and a second major surface, where the first major surface of the back faces the first major surface of the body when the back is connected to the head. The head also includes a bristle extending through the body and beyond the second major surface of the body.

Abstract: Methods, apparatus, systems and articles of manufacture are disclosed to assess compliance of a virtual computing environment. An example method disclosed herein to assess compliance of computing resources of a computing environment includes monitoring for an occurrence of a change in a computing resource in the computing environment, and in response to detecting the occurrence and without waiting for batch testing, assessing compliance of the computing resource with a compliance policy.

Abstract: Computerized systems and methods are provided for integrating copy data tokens with source code repositories. A first command associated with the version control system stores in the memory a copy of source code and a copy of the data token from the remote repository, comprising source data and mount data. A second command associated with the version control system is executed to create a version of the source code stored in the memory. Based on the execution of the second command a working copy of the copy data is created based on the data token for use with the version of the source code, comprising creating a copy of the copy data from the data source based on the source data, and mounting the working copy to the device based on the mount data, thereby automatically managing the copy data for the version control system.

Abstract: A gearbox housing of an aircraft includes a surface configured to contact with and support a load of a component of the aircraft such that the surface is susceptible to corrosion. The surface has an area from which a portion of material was removed. A structural deposit is formed by cold spraying one or more layers of powdered material within the area. The structural deposit is configured to share the load applied to the surface by the component.

Abstract: Various embodiments of a livestock grooming article and method of forming same are disclosed. The livestock grooming article includes a handle extending along a handle axis, and a head extending along a head axis and connected to the handle. The head includes a body including a first major surface and a second major surface, and a back slidably connected to the first major surface of the body. The back includes a first major surface and a second major surface, where the first major surface of the back faces the first major surface of the body when the back is connected to the head. The head also includes a bristle extending through the body and beyond the second major surface of the body.