Patents by Inventor James T. Kellis

James T. Kellis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fabric and home care products comprising cold water proteases
    Patent number: 8785171
    Abstract: This invention relates to fabric and home care products comprising one or more cold water proteases and processes for making and using such products. Such compositions provide improved cleaning and freshness. Such cold water proteases may be derived from parent enzymes, including BPN? subtilisin and subtilisin derived from Bacillus lentus, by substitution, insertion and/or deletion of one or more of the parent enzymes' amino acids.
    Type: Grant
    Filed: December 9, 2010
    Date of Patent: July 22, 2014
    Assignee: The Procter & Gamble Company
    Inventors: Philip Frank Souter, Glenn Steven Ward, Viktor Yuryevich Alekseyev, Joshua Roy Basler, Luis Gustavo Cascão-Pereira, David A. Estell, Ayrookaran J. Poulose, James T. Kellis, Jr., Alexander Pisarchik, Daniel Esteban Torres-Pazmino
  • FABRIC AND HOME CARE PRODUCTS
    Publication number: 20140193888
    Abstract: This invention relates to fabric and home care products comprising one or more cold water proteases and processes for making and using such products. Such compositions provide improved cleaning and freshness. Such cold water proteases may be derived from parent enzymes, including BPN? subtilisin and subtilisin derived from Bacillus lentus, by substitution, insertion and/or deletion of one or more of the parent enzymes' amino acids.
    Type: Application
    Filed: March 12, 2014
    Publication date: July 10, 2014
    Applicant: The Procter & Gamble Company
    Inventors: Philip Frank SOUTER, Glenn Steven WARD, Viktor Yuryevich ALEKSEYEV, Joshua Roy BASLER, Luis Gustavo CASAO-PEREIRA, David A ESTELL, Ayrookaran J Poulose, James T KELLIS, JR., Alexander PISARCHIK, Daniel TORRES-PAZMINO
  • Protease comprising one or more combinable mutations
    Patent number: 8753861
    Abstract: The present invention provides engineered protease variants. In particular, the protease variants comprise combinable mutations at selected surface positions that affect the charge and/or hydrophobicity of the enzyme to enhance at least one desired property of the resulting variant enzyme in a chosen application. Compositions comprising the protease variants, and methods for using the same are also provided.
    Type: Grant
    Filed: November 10, 2009
    Date of Patent: June 17, 2014
    Assignee: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, David A. Estell, James T. Kellis, Jr.
  • Compositions and Methods Comprising Serine Protease Variants
    Publication number: 20140154782
    Abstract: The present invention provides serine protease variants, more specifically subtilisin variants produced there from. Specifically, the present invention provides serine protease variants, more specifically subtilisin variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants, more specifically subtilisin variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants, more specifically subtilisin variants.
    Type: Application
    Filed: May 4, 2012
    Publication date: June 5, 2014
    Applicant: DANISCO US INC.
    Inventors: Neelam S. Amin, Katherine Augustyn, Joshua R. Basler, Luis G. Cascao-Pereira, Katherine D. Collier, Edward M. Concar, David A. Estell, James T. Kellis, JR., Euan John Magennis, Alexander Pisarchik, Ayrookaran J. Poulose, Philip Frank Souter, Glenn Steven Ward, Jian Yao
  • Compositions and methods comprising protease variants
    Patent number: 8728790
    Abstract: The present invention provides protease variants, compositions comprising protease variants, and methods of using such protease variants and compositions.
    Type: Grant
    Filed: December 9, 2010
    Date of Patent: May 20, 2014
    Assignee: Danisco US Inc.
    Inventors: Joshua R Basler, Luis G Cascão-Pereira, David A Estell, James T Kellis, Jr., Alexander Pisarchik, Ayrookaran J. Poulose, Daniel E. Torres Pazmino
  • TS-23 Alpha-Amylase Variants With Altered Properties
    Publication number: 20130344542
    Abstract: Described are variants (mutants) of a parent alpha-amylase having alpha-amylase activity and exhibiting altered properties relative to the parent alpha-amylase, and methods of use, thereof.
    Type: Application
    Filed: May 21, 2013
    Publication date: December 26, 2013
    Inventors: Luis G. Cascao-Pereira, Claudine Chang, Clement Choy, James T. Kellis, JR., Brian E. Jones, Melodie Estabrook, Marc Kolkman, Chris Leeflang, Casper Vroemen, Walter Weyler
  • ISOPRENE SYNTHASE VARIANTS FOR IMPROVED MICROBIAL PRODUCTION OF ISOPRENE
    Publication number: 20130260432
    Abstract: The present invention provides methods and compositions comprising at least one isoprene synthase enzyme with improved catalytic activity and/or solubility. In particular, the present invention provides variant plant isoprene synthases for increased isoprene production in microbial host cells. Biosynthetically produced isoprene of the present invention finds use in the manufacture of rubber and elastomers.
    Type: Application
    Filed: March 30, 2012
    Publication date: October 3, 2013
    Applicant: Danisco US Inc.
    Inventors: Richard R. BOTT, Marguerite A. Cervin, James T. Kellis, JR., Joseph C. McAuliffe, Andrei Miasnikov, Caroline M. Peres, Christopher Lee Rife, Derek H. Wells, Walter Weyler, Gregory M. Whited
  • COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS (AS AMENDED)
    Publication number: 20130260438
    Abstract: The present invention provides serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Application
    Filed: May 5, 2011
    Publication date: October 3, 2013
    Applicant: Danisco US Inc.
    Inventors: Viktor Yuryevich Alekseyev, Neelam A Amin, Katherine Auguslyn, Luis Gustavo Cascao-Pereira, Katherine D. Collier, David A. Estell, James T. Kellis, JR., Ayrookaran J. Poulose, Philip Frank Souter, Glenn Steven Ward, Jian Yao
  • TS-23 alpha-amylase variants with altered properties
    Patent number: 8460916
    Abstract: Described are variants (mutants) of a parent alpha-amylase having alpha-amylase activity and exhibiting altered properties relative to the parent alpha-amylase, and methods of use, thereof.
    Type: Grant
    Filed: July 2, 2012
    Date of Patent: June 11, 2013
    Assignee: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, Claudine Chang, Clement Choy, James T. Kellis, Jr., Brian E. Jones, Melodie Estabrook, Marc Koklman, Chris Leeflang, Casper Vroeman, Walter Weyler
  • ALPHA-AMYLASE VARIANTS WITH ALTERED PROPERTIES
    Publication number: 20130011882
    Abstract: Disclosed are compositions comprising variants of alpha-amylase that have alpha-amylase activity and which exhibit altered properties relative to a parent AmyS-like alpha-amylase from which they are derived. The compositions comprise an additional enzyme such as a phytase. Also disclosed are methods of using the compositions, and kits related thereto.
    Type: Application
    Filed: May 15, 2012
    Publication date: January 10, 2013
    Applicant: DANISCO US INC.
    Inventors: LUIS G. CASCÃO-PEREIRA, JAMES T. KELLIS, JR., BRADLEY A. PAULSON, SCOTT D. POWER, SANDRA W. RAMER, VIVEK SHARMA, ANDREW SHAW, JAYARAMA K. SHETTY, DONALD E. WARD
  • TS-23 ALPHA-AMYLASE VARIANTS WITH ALTERED PROPERTIES
    Publication number: 20130005029
    Abstract: Described are variants (mutants) of a parent alpha-amylase having alpha-amylase activity and exhibiting altered properties relative to the parent alpha-amylase, and methods of use, thereof.
    Type: Application
    Filed: July 2, 2012
    Publication date: January 3, 2013
    Applicant: Danisco US Inc., Genencor Division
    Inventors: Luis G. CASCAO-PEREIRA, Claudine Chang, Clement Choy, James T. Kellis, JR., Brain E. Jones, Melodie Estabrook, Marc Kolkman, Chris Leeflang, Casper Vroemen, Walter Weyler
  • TS23 alpha-amylase variants with altered properties
    Patent number: 8236545
    Abstract: Described are variants (mutants) of a parent alpha-amylase having alpha-amylase activity and exhibiting altered properties relative to the parent alpha-amylase, and methods of use, thereof.
    Type: Grant
    Filed: February 4, 2009
    Date of Patent: August 7, 2012
    Assignee: Danisco US Inc., Genencor Division
    Inventors: Luis G. Cascao-Pereira, Claudine Chang, Clement Choy, James T. Kellis, Jr., Brian E Jones, Melodie Estabrook, Marc Kolkman, Chris Leeflang, Casper Vroemen, Walter Weyler
  • Alpha-amylase variants with altered properties
    Patent number: 8206966
    Abstract: Disclosed are compositions comprising variants of alpha-amylase that have alpha-amylase activity and which exhibit altered properties relative to a parent AmyS-like alpha-amylase from which they are derived. The compositions comprise an additional enzyme such as a phytase. Also disclosed are methods of using the compositions, and kits related thereto.
    Type: Grant
    Filed: November 3, 2008
    Date of Patent: June 26, 2012
    Assignee: Danisco US Inc.
    Inventors: Luis G. Cascāo-Pereira, James T. Kellis, Jr., Bradley A. Paulson, Scott D. Power, Sandra W. Ramer, Vivek Sharma, Andrew Shaw, Jayarama K. Shetty, Donald E. Ward
  • Compositions and methods comprising a subtilisin variant
    Patent number: 8183024
    Abstract: The present invention provides a subtilisin variant that is particularly well suited to cleaning applications. In particular, the present invention provides a Bacillus sp. subtilisin variant and cleaning compositions comprising this variant.
    Type: Grant
    Filed: November 10, 2009
    Date of Patent: May 22, 2012
    Assignee: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, Jr., Ayrookaran J. Poulise
  • Isoprene synthase variants for improved microbial production of isoprene
    Patent number: 8173410
    Abstract: The present invention provides methods and compositions comprising at least one isoprene synthase enzyme with improved catalytic activity and/or solubility. In particular, the present invention provides variant plant isoprene synthases for increased isoprene production in microbial host cells. Biosynthetically produced isoprene of the present invention finds use in the manufacture of rubber and elastomers.
    Type: Grant
    Filed: April 23, 2009
    Date of Patent: May 8, 2012
    Assignee: Danisco US Inc.
    Inventors: Richard R. Bott, Marguerite A. Cervin, James T. Kellis, Jr., Joseph C. McAuliffe, Andrei Miasnikov, Caroline M. Peres, Christopher Lee Rife, Derek H. Wells, Walter Weyler, Gregory M. Whited
  • Protease Comprising One Or More Combinable Mutations
    Publication number: 20120003718
    Abstract: The present invention provides engineered protease variants. In particular, the protease variants comprise combinable mutations at selected surface positions that affect the charge and/or hydrophobicity of the enzyme to enhance at least one desired property of the resulting variant enzyme in a chosen application. Compositions comprising the protease variants, and methods for using the same are also provided.
    Type: Application
    Filed: November 10, 2009
    Publication date: January 5, 2012
    Applicant: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, David A. Estell, James T. Kellis, JR.
  • Compositions and Methods Comprising Protease Variants
    Publication number: 20110262999
    Abstract: The present invention provides protease variants, compositions comprising protease variants, and methods of using such protease variants and compositions.
    Type: Application
    Filed: December 9, 2010
    Publication date: October 27, 2011
    Applicant: Danisco US Inc.
    Inventors: Joshua R. Basler, Luis G. Cascão-Pereira, David A. Estell, James T. Kellis, JR., Alexander Pisarchik, Ayrookaran J. Poulose, Daniel Torres Pazmino
  • Compositions And Methods Comprising Variant Microbial Proteases
    Publication number: 20110256610
    Abstract: The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant proteases suitable for laundry cleaning applications.
    Type: Application
    Filed: June 3, 2009
    Publication date: October 20, 2011
    Inventors: Viktor Yuryevich Alekseyev, Luis G. Cascao-Pereira, James T. Kellis, JR., Alexander Pisarchik
  • Compositions And Methods Comprising Variant Microbial Proteases
    Publication number: 20110256609
    Abstract: The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant subtilisins suitable for laundry cleaning applications.
    Type: Application
    Filed: June 3, 2009
    Publication date: October 20, 2011
    Inventors: Joshua R. Basler, Luis G. Cascao-Pereira, David A. Estell, James T. Kellis, JR.
  • Compositions And Methods Comprising Variant Microbial Proteases
    Publication number: 20110251073
    Abstract: The present invention provides methods for protein engineering. Specifically, the invention provides methods utilizing site evaluation libraries to design libraries that optimize two or more properties of a protein. The present invention also provides variant subtilisins suitable for various uses.
    Type: Application
    Filed: June 3, 2009
    Publication date: October 13, 2011
    Inventors: Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, JR.