Patents by Inventor James T. Palmer

James T. Palmer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170305943
    Abstract: Compounds and methods are provided for treating bacterial infections.
    Type: Application
    Filed: May 21, 2015
    Publication date: October 26, 2017
    Applicant: TAXIS Pharmaceuticals, Inc.
    Inventors: David Ryall Brown, Ian Collins, Lloyd George Czaplewski, David John Haydon, Penelope Anne Mayes, Jeffrey Peter Mitchell, James T Palmer, Neil Robert Stokes
  • Publication number: 20170260178
    Abstract: The present invention provides a compound of the following formula, salts, racemates, diastereomers, enantiomers, esters, carbamates, phosphates, sulfates, deuterated forms and prodrugs thereof. Also provided is the use of these compounds as antibacterials, compositions comprising them and processes for their manufacture.
    Type: Application
    Filed: March 27, 2017
    Publication date: September 14, 2017
    Inventors: Christopher James Lunniss, James T. Palmer, Gary Robert William Pitt, Lorraine Claire Axford, David Davies
  • Patent number: 9651520
    Abstract: A capillary electrophoresis system which provides a microfluidic chip for capillary electrophoresis and a microfluidic interface module which fluidicly couples the microfluidic chip to external fluid sources and or external repositories.
    Type: Grant
    Filed: February 25, 2011
    Date of Patent: May 16, 2017
    Assignee: Mettler-Toledo Thornton, Inc.
    Inventors: Philippe M. Dekleva, Jonathan A. Vickers, James T. Palmer
  • Patent number: 9604976
    Abstract: The present invention provides a compound of the following formula, salts, racemates, diastereomers, enantiomers, esters, carbamates, phosphates, sulfates, deuterated forms and prodrugs thereof. Also provided is the use of these compounds as antibacterials, compositions comprising them and processes for their manufacture.
    Type: Grant
    Filed: March 21, 2013
    Date of Patent: March 28, 2017
    Assignee: SPERO GYRASE, INC.
    Inventors: Christopher James Lunniss, James T. Palmer, Gary Robert William Pitt, Lorraine Claire Axford, David Davies
  • Publication number: 20170007615
    Abstract: The present disclosure relates to a novel combination of compounds, their use as antibacterials, compositions comprising them and methods for treating or preventing bacterial infections, more particularly, bacterial infections caused by Gram-negative pathogens and/or drug resistant Gram-negative bacteria.
    Type: Application
    Filed: February 3, 2015
    Publication date: January 12, 2017
    Inventors: Ian Collins, David John Haydon, Helena Thomaides-Brears, James T Palmer, Christopher James Lunniss
  • Patent number: 9511073
    Abstract: The present invention provides compounds of Formula (I): and salts, racemates, isomers, diastereoisomers, enantiomers, hydrates, solvates, N-oxides, pharmaceutically acceptable derivatives or prodrugs thereof. Also provided the use of these compounds as antibacterials, compositions comprising them and processes for their manufacture.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: December 6, 2016
    Assignee: TAXIS Pharmaceuticals, Inc.
    Inventors: David John Haydon, Lloyd George Czaplewski, Neil Robert Stokes, David Davies, Ian Collins, James T. Palmer, Jeffrey Peter Mitchell, Gary Robert William Pitt, Daniel Offermann
  • Publication number: 20150329530
    Abstract: The present invention provides a compound of the following formula, salts, racemates, diastereomers, enantiomers, esters, carbamates, phosphates, sulfates, deuterated forms and prodrugs thereof. Also provided is the use of these compounds as antibacterials, compositions comprising them and processes for their manufacture.
    Type: Application
    Filed: March 21, 2013
    Publication date: November 19, 2015
    Inventors: Christopher James LUNNISS, James T. PALMER, Gary Robert William PITT, Lorraine Claire AXFORD, David DAVIES
  • Patent number: 9181234
    Abstract: The present invention provides a compound of the following formula and salts thereof: Also provided is the use of these compounds as antibacterials, compositions comprising them and processes for their manufacture.
    Type: Grant
    Filed: October 7, 2011
    Date of Patent: November 10, 2015
    Assignee: Biota Europe Ltd.
    Inventors: James T Palmer, Christopher James Lunnis, Daniel A Offermann, Lorraine Claire Axford, Michael Blair, Dale Mitchell, Nicholas Palmer, Christopher Steele, John Atherall, David Watson, David Haydon, Lloyd Czaplewski, David Davies, Ian Collins, Edward Malcolm Tyndall, Laura Andrau, Gary Robert William Pitt
  • Patent number: 9121824
    Abstract: A microfluidic chip interface for providing fluid communication with external fluid sources and external fluid waste containers, and for providing electrical contact with voltage sources and voltage and current measuring devices, is described. The microchip is first placed into electrical communication with at least one electrical source and at least one electronic measurement device, and reversibly secured in place. Chosen fluids are provided into the microchip and directed through the chip using a fluid manifold having dispensing tubes and fluid aspiration tubes, which is brought into the vicinity of the secured microchip. The distance between the fluid manifold and the microchip is chosen such that the injection tubes are located within wells in the microchip connected to microfluidic channels, and the aspiration tubes are located near the surface of the microchip in the vicinity of the wells such that fluid spillage onto the surface of the microchip during fluid transfer is avoided.
    Type: Grant
    Filed: November 14, 2012
    Date of Patent: September 1, 2015
    Assignee: METTLER-TOLEDO THORNTON, INC.
    Inventors: James T. Palmer, Philippe M. Dekleva
  • Patent number: 9029386
    Abstract: Derivatives of pyridine of the formula wherein one of Y and A is CR and the other is N are kinase inhibitors useful in treating conditions associated with excess kinase activity.
    Type: Grant
    Filed: January 22, 2013
    Date of Patent: May 12, 2015
    Assignee: Gilead Sciences, Inc.
    Inventors: Christopher John Burns, Michael Francis Harte, James T. Palmer
  • Patent number: 8906902
    Abstract: The present invention provides a compound of the following formula, salts, racemates, diastereomers, enantiomers, esters, carbamates, phosphates, sulfates, deuterated forms and prodrugs thereof. Also provided is the use of these compounds as antibacterials, compositions comprising them and processes for their manufacture.
    Type: Grant
    Filed: March 21, 2013
    Date of Patent: December 9, 2014
    Assignee: Biota Europe Limited
    Inventors: Christopher James Lunniss, James T. Palmer, Gary Robert William Pitt, David Davies, Lorraine Claire Axford
  • Publication number: 20140256743
    Abstract: This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.
    Type: Application
    Filed: May 20, 2014
    Publication date: September 11, 2014
    Applicants: Merck Frosst Canada Ltd., Axys Pharmaceuticals, Inc.
    Inventors: Christopher I. Bayly, Cameron Black, Serge Leger, Chun Sing Li, Dan McKay, Christophe Mellon, Jacques Yves Gauthier, Vouy-Linh Truong, Cheuk Lau, Michel Therien, Michael J. Green, Bernard L. Hirschbein, James William Janc, James T. Palmer, Chitra I. Baskaran
  • Patent number: 8772336
    Abstract: This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.
    Type: Grant
    Filed: October 11, 2012
    Date of Patent: July 8, 2014
    Assignees: Merck Frosst Canada Ltd., Axys Pharmaceuticals, Inc.
    Inventors: Christopher I. Bayly, Cameron Black, Serge Leger, Chun Sing Li, Dan McKay, Christophe Mellon, Jacques Yves Gauthier, Vouy-Linh Truong, Cheuk Lau, Michel Therien, Michael J. Green, Bernard L. Hirschbein, James William Janc, James T. Palmer, Chitra I. Baskaran
  • Publication number: 20140135332
    Abstract: The present invention provides compounds of Formula (I): and salts, racemates, isomers, diastereoisomers, enantiomers, hydrates, solvates, N-oxides, pharmaceutically acceptable derivatives or prodrugs thereof. Also provided the use of these compounds as antibacterials, compositions comprising them and processes for their manufacture.
    Type: Application
    Filed: April 20, 2012
    Publication date: May 15, 2014
    Applicant: BIOTA SCIENTIFIC MANAGEMENT PTY LTD
    Inventors: David John Haydon, Lloyd George Czaplewski, Neil Robert Stokes, David Davies, Ian Collins, James T Palmer, Jeffrey Peter Mitchell, Gary Robert William Pitt, Daniel Offermann
  • Publication number: 20130313116
    Abstract: A microfluidic chip interface for providing fluid communication with external fluid sources and external fluid waste containers, and for providing electrical contact with voltage sources and voltage and current measuring devices, is described. The microchip is first placed into electrical communication with at least one electrical source and at least one electronic measurement device, and reversibly secured in place. Chosen fluids are provided into the microchip and directed through the chip using a fluid manifold having dispensing tubes and fluid aspiration tubes, which is brought into the vicinity of the secured microchip. The distance between the fluid manifold and the microchip is chosen such that the injection tubes are located within wells in the microchip connected to microfluidic channels, and the aspiration tubes are located near the surface of the microchip in the vicinity of the wells such that fluid spillage onto the surface of the microchip during fluid transfer is avoided.
    Type: Application
    Filed: November 14, 2012
    Publication date: November 28, 2013
    Inventors: James T. Palmer, Philippe M. Dekleva
  • Publication number: 20130252938
    Abstract: The present invention provides a compound of the following formula, salts, racemates, diastereomers, enantiomers, esters, carbamates, phosphates, sulfates, deuterated forms and prodrugs thereof. Also provided is the use of these compounds as antibacterials, compositions comprising them and processes for their manufacture.
    Type: Application
    Filed: March 21, 2013
    Publication date: September 26, 2013
    Applicant: Biota Europe Ltd.
    Inventors: Christopher James Lunniss, James T. Palmer, Gary Robert William Pitt, David Davies, Lorraine Claire Axford
  • Publication number: 20130248369
    Abstract: A capillary electrophoresis system which provides a microfluidic chip for capillary electrophoresis and a microfluidic interface module which fluidicly couples the microfluidic chip to external fluid sources and or external repositories.
    Type: Application
    Filed: February 25, 2011
    Publication date: September 26, 2013
    Applicant: Advanced Micro Labs ,LLC
    Inventors: Philippe M. Dekleva, Jonathan A. Vickers, James T. Palmer
  • Patent number: 8461161
    Abstract: Compunds of the general formula wherein each of Z1-Z4 is N or CR1 wherein only two of said Z1-Z4 may be N are useful as kinase inhibitors.
    Type: Grant
    Filed: November 15, 2007
    Date of Patent: June 11, 2013
    Assignee: YM Biosciences Australia Pty Ltd
    Inventors: Christopher John Burns, Michael Francis Harte, James T. Palmer
  • Patent number: 8318748
    Abstract: This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.
    Type: Grant
    Filed: May 25, 2011
    Date of Patent: November 27, 2012
    Assignees: Merck, Sharp & Dohme Corp., Axys Pharmaceuticals, Inc.
    Inventors: Christopher I. Bayly, Cameron Black, Serge Leger, Chun Sing Li, Dan McKay, Christophe Mellon, Jacques Yves Gauthier, Vouy-Linh Truong, Cheuk Lau, Michel Therien, Michael J. Green, Bernard L. Hirschbein, James William Janc, James T. Palmer, Chitra Baskaran
  • Publication number: 20120108547
    Abstract: Disclosed herein are compounds that inhibit the activity of particular tyrosine kinases. Methods for the preparation of such compounds are disclosed. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the compounds disclosed, alone or in combination with other therapeutic agents, for the treatment of tyrosine kinase-mediated diseases or conditions or tyrosine kinase-dependent diseases or conditions are provided.
    Type: Application
    Filed: December 22, 2011
    Publication date: May 3, 2012
    Applicant: Pharmacyclics, Inc.
    Inventors: Orion D. Jankowski, James T. Palmer, Lee Honigberg