Patents by Inventor James Thomson

James Thomson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220192195
    Abstract: The present invention relates novel herbicidal combinations and their use in controlling plants or inhibiting plant growth. In particular, herbicidal combinations of the invention comprise at least one pyridazine derivative as defined herein, in combination with at least one further herbicide that is an acetoclactase synthase (ALS) inhibitor.
    Type: Application
    Filed: January 30, 2020
    Publication date: June 23, 2022
    Applicant: SYNGENTA CROP PROTECTION AG
    Inventors: Nigel James WILLETTS, Gavin John HALL, Niall Rae THOMSON, Julia FELLMANN, Raymond Joseph WUERFFEL, Ravindra SONAWANE, Mangala PHADTE, Sandeep Reddy KANDUKURI, Sarah ARMSTRONG, Sean NG, Andrea MCGRANAGHAN, James Nicholas SCUTT, Sian Janet MOORHOUSE
  • Patent number: 11362500
    Abstract: A mounting device (110) for an elongate flexible member extending through an aperture (102), comprising: an elongate body (130) having a longitudinal axis; an internal passageway passing through the elongate body (130) parallel to the longitudinal axis, for receipt of the elongate flexible member; a plurality of apertures (132) in the elongate body (130); an engagement member (136) in each apertures (132) and constrained to move along a displacement axis inclined to the longitudinal axis of the elongate body (130); a plurality of actuation members (142), each engaged with a respective engagement member (136), whereby displacement of the actuation member (142) in a first direction displaces the engagement members (136) outwardly to project beyond the periphery of the elongate body (130) and displacement of the actuations members (142) in a second, opposite direction displaces the engagement members (136) inwardly; and biasing means (182) biasing the actuation members (142) in the first direction.
    Type: Grant
    Filed: January 29, 2019
    Date of Patent: June 14, 2022
    Assignee: First Subsea Limited
    Inventors: Anthony John Little, Craig Richard Thomson, Stephen James Bennett
  • Publication number: 20220159956
    Abstract: The present invention relates to herbicidal combinations and their use in controlling plants or inhibiting plant growth. In particular, herbicidal combinations comprising at least one pyridazine derivative of Formula (I) as defined herein, in combination with at least one further herbicide that is a compound of Formula (II) as defined herein.
    Type: Application
    Filed: January 30, 2020
    Publication date: May 26, 2022
    Applicant: SYNGENTA CROP PROTECTION AG
    Inventors: Nigel James WILLETTS, Gavin John HALL, Niall Rae THOMSON, Julia FELLMANN, Raymond Joseph WUERFFEL, Ravindra SONAWANE, Mangala PHADTE, Sandeep Reddy KANDUKURI, Sarah ARMSTRONG, Sean NG, Andrea MCGRANAGHAN, James Nicholas SCUTT, Sian Janet MOORHOUSE
  • Publication number: 20220142162
    Abstract: The present invention relates to novel herbicidal combinations and their use in controlling plants or inhibiting plant growth. In particular, herbicidal combinations of the invention comprise at least one pyridazine derivative of Formula (I), in combination with at least one further herbicide that is a non-selective herbicide, a herbicide that acts through the inhibition of protoporphoryinogen oxidase, or a herbicide that inhibits photosystem II in photosynthesis.
    Type: Application
    Filed: January 30, 2020
    Publication date: May 12, 2022
    Applicant: SYNGENTA CROP PROTECTION AG
    Inventors: Nigel James WILLETTS, Gavin John HALL, Niall Rae THOMSON, Julia FELLMANN, Raymond Joseph WUERFFEL, Ravindra SONAWANE, Mangala PHADTE, Sandeep Reddy KANDUKURI, Sarah ARMSTRONG, Sean NG, Andrea MCGRANAGHAN, James Nicholas SCUTT, Sian Janet MOORHOUSE
  • Publication number: 20220105160
    Abstract: The present invention relates generally to isolated to arginine deiminase (ADI) proteins that have reduced cross-reactivity with anti-ADI-PEG 20 antibodies as compared to ADI-PEG 20, but which can have functional characteristics comparable to or better than ADI-PEG 20, compositions comprising the ADI proteins, and related methods of treating arginine-dependent diseases or related diseases such as cancer.
    Type: Application
    Filed: December 20, 2021
    Publication date: April 7, 2022
    Inventors: Robert ALMASSY, Richard E. SHOWALTER, James A. THOMSON, Wes SISSON, Wei-Jong SHIA, Li-Chang CHEN, Yang LEE
  • Patent number: 11286226
    Abstract: Disclosed are new polycyclic carbogenic molecules and their methods of synthesis. The new polycyclic carbogenic molecules may be utilized in anti-cancer therapies. In particular, the polycyclic carbogenic molecules may be formulated as pharmaceutical compositions that comprise the small molecules, which compositions may be administered in methods of treating and/or preventing cell proliferative diseases and disorders such as cancer. The new polycyclic carbogenic molecules may be prepared from vinyl- or allyl-substituted cyclohexenone precursors via preparation of a silyl bis-enol ether intermediate.
    Type: Grant
    Filed: September 21, 2018
    Date of Patent: March 29, 2022
    Assignee: Northwestern University
    Inventors: Regan James Thomson, Emily E. Robinson
  • Publication number: 20220090009
    Abstract: The present invention relates to chemically defined and xenogeneic material-free methods for deriving endothelial cells from human pluripotent stem cells. In particular, the present invention provides highly efficient and reproducible methods of obtaining human endothelial cells from human pluripotent stem cells, where endothelial cells derived from the methods provided herein are suitable for clinically relevant therapeutic applications.
    Type: Application
    Filed: December 1, 2021
    Publication date: March 24, 2022
    Inventors: James A. Thomson, Jue Zhang
  • Publication number: 20220033773
    Abstract: The present invention relates to methods for deriving human hematopoietic progenitors, primitive macrophages, and microglial cells from human pluripotent stem cells. In particular, provided herein are highly efficient and reproducible methods of obtaining human primitive macrophages and microglia from human pluripotent stem cells, where the primitive macrophages and microglia can be suitable for clinically relevant therapeutic applications.
    Type: Application
    Filed: August 18, 2021
    Publication date: February 3, 2022
    Inventors: James A. Thomson, Nicholas E. Propson, Michael P. Schwartz, Zhonggang Hou, Gene I. Uenishi, Igor I Slukvin, William L. Murphy, Jue Zhang
  • Patent number: 11235037
    Abstract: The present invention relates generally to isolated to arginine deiminase (ADI) proteins that have reduced cross-reactivity with anti-ADI-PEG 20 antibodies as compared to ADI-PEG 20 (pegylated ADI derived from M. hominis), but which can have functional characteristics comparable to or better than ADI-PEG 20, compositions comprising the ADI proteins, and related methods of treating arginine-dependent diseases or related diseases such as cancer.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: February 1, 2022
    Assignee: Polaris Group
    Inventors: Robert Almassy, Richard E. Showalter, James A. Thomson, Wes Sisson, Wei-Jong Shia, Li-Chang Chen, Yang Lee
  • Publication number: 20220017873
    Abstract: The present invention relates to three-dimensional (3D) tissue constructs and methods of using such 3D tissue constructs to screen for neurotoxic agents. In particular, provided herein are methods of producing and using complex, highly uniform human tissue models comprising physiologically relevant human cells, where the tissue models have the degree of sample uniformity and reproducibility required for use in quantitative high-throughput screening applications.
    Type: Application
    Filed: July 12, 2021
    Publication date: January 20, 2022
    Inventors: James A. Thomson, William L. Murphy, Charles D. Page, Michael P. Schwartz, Zhonggang Hou
  • Publication number: 20220016178
    Abstract: This disclosure relates generally to new methods of maintaining the expression of hepatic genes in human hepatocytes and method for maintaining the functional hepatic enzyme activity of primary hepatocytes in culture. The disclosure also encompasses new methods of deriving a population of pure hepatocytes without selecting or sorting the cells from the cultured pluripotent cells.
    Type: Application
    Filed: July 27, 2021
    Publication date: January 20, 2022
    Inventors: James A. Thomson, Srikumar Sengupta
  • Publication number: 20220013224
    Abstract: Medical devices, systems, and methods related thereto a glucose monitoring system having a first display unit in data communication with a skin-mounted assembly, the skin-mounted assembly including an in vivo sensor and a transmitter. The first display unit and a second display unit are in data communication with a data management system. The first display unit comprises memory that grants a first user first access level rights and the second display unit comprises memory that grants a second individual second access level rights.
    Type: Application
    Filed: June 22, 2021
    Publication date: January 13, 2022
    Applicant: Abbott Diabetes Care Inc.
    Inventors: Christopher V. Reggiardo, Namvar Kiaie, James Thomson
  • Publication number: 20220010331
    Abstract: Methods for reprogramming primate somatic cells to pluripotency using an episomal vector that does not encode an infectious virus are disclosed. Pluripotent cells produced in the methods are also disclosed.
    Type: Application
    Filed: June 21, 2021
    Publication date: January 13, 2022
    Inventors: James Thomson, Junying Yu
  • Patent number: 11220672
    Abstract: The present invention relates to chemically defined and xenogeneic material-free methods for deriving endothelial cells from human pluripotent stem cells. In particular, the present invention provides highly efficient and reproducible methods of obtaining human endothelial cells from human pluripotent stem cells, where endothelial cells derived from the methods provided herein are suitable for clinically relevant therapeutic applications.
    Type: Grant
    Filed: December 31, 2015
    Date of Patent: January 11, 2022
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: James A. Thomson, Jue Zhang
  • Publication number: 20220000689
    Abstract: There is disclosed a patient restraint assembly including a head restraint configured to extend around the patient's head, at least one securement member (4) extending from the first end of the head restraint, and at least one securement member (5) extending from the second end of the head restraint, said securement members (4, 5) being configured to releasably secure said head restraint to a support table, an adjustment unit (15) to adjust the tension in the securement member(s) (4, 5), wherein adjustment of the adjustment unit (15) applies the same force simultaneously to the securement member(s) (4) at the first end and the securement member(s) (5) at the second end of the head restraint.
    Type: Application
    Filed: November 6, 2019
    Publication date: January 6, 2022
    Inventors: Jonathan James Gordon, Kevin James Thomson
  • Patent number: 11216526
    Abstract: Systems and methods are provided methods for providing an online interface for displaying hierarchically or logically arranged user-generated content. One method including receiving, from a first user over a network, topical user-generated electronic content, the topical user-generated electronic content being related to a topic of a web page; displaying the topical user-generated electronic content received from the first user on the web page; receiving, from a second user over the network, responsive user-generated electronic content and an indication of a desire to post the responsive user-generated electronic content on the web page in association with the topical user-generated electronic content; and displaying, adjacent to the topical user-generated electronic content on the web page, a user element or link that a third user can manipulate to display the responsive user-generated electronic content adjacent to the topical user-generated electronic content.
    Type: Grant
    Filed: May 3, 2019
    Date of Patent: January 4, 2022
    Assignee: Verizon Patent and Licensing Inc.
    Inventors: MacGregor James Thomson, Thomas Biegeleisen, Siobhan Dooley
  • Publication number: 20210398663
    Abstract: Medical devices, systems, and methods related thereto a glucose monitoring system having a first display unit in data communication with a skin-mounted assembly, the skin-mounted assembly including an in vivo sensor and a transmitter. The first display unit and a second display unit are in data communication with a data management system. The first display unit comprises memory that grants a first user first access level rights and the second display unit comprises memory that grants a second individual second access level rights.
    Type: Application
    Filed: September 1, 2021
    Publication date: December 23, 2021
    Applicant: Abbott Diabetes Care Inc.
    Inventors: Christopher V. Reggiardo, Namvar Kiaie, James Thomson
  • Patent number: 11124765
    Abstract: The present invention relates to methods for deriving human hematopoietic progenitors, primitive macrophages, and microglial cells from human pluripotent stem cells. In particular, provided herein are highly efficient and reproducible methods of obtaining human primitive macrophages and microglia from human pluripotent stem cells, where the primitive macrophages and microglia can be suitable for clinically relevant therapeutic applications.
    Type: Grant
    Filed: September 21, 2018
    Date of Patent: September 21, 2021
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: James A. Thomson, Nicholas E. Propson, Michael P. Schwartz, Zhonggang Hou, Gene I. Uenishi, Igor I. Slukvin, William L. Murphy, Jue Zhang
  • Patent number: 11116799
    Abstract: This disclosure relates generally to new methods of maintaining the expression of hepatic genes in human hepatocytes and method for maintaining the functional hepatic enzyme activity of primary hepatocytes in culture. The disclosure also encompasses new methods of deriving a population of pure hepatocytes without selecting or sorting the cells from the cultured pluripotent cells.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: September 14, 2021
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: James A. Thomson, Srikumar Sengupta
  • Patent number: 11060066
    Abstract: The present invention relates to three-dimensional (3D) tissue constructs and methods of using such 3D tissue constructs to screen for neurotoxic agents. In particular, provided herein are methods of producing and using complex, highly uniform human tissue models comprising physiologically relevant human cells, where the tissue models have the degree of sample uniformity and reproducibility required for use in quantitative high-throughput screening applications.
    Type: Grant
    Filed: December 31, 2015
    Date of Patent: July 13, 2021
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: James A. Thomson, William L. Murphy, Charles D. Page, Michael P. Schwartz, Zhonggang Hou