Abstract: A waveguide assembly for delivering focused acoustic energy includes a housing comprising a chamber filled with a medium for propagating acoustic waves. An acoustic transducer is supported the housing and has a surface facing into the chamber. The surface is configured to transmit acoustic waves into the chamber through the medium toward a focus zone. The waveguide assembly also includes structure configured to focus the acoustic waves transmitted from the surface of the acoustic transducer. The waveguide assembly further includes a flexible elongated waveguide having a first end positioned in the chamber opposite the curved surface, and a second end outside the chamber. The waveguide has a tubular configuration with an inner lumen in fluid communication with the chamber via the first end and being filled with the medium. The first end of the waveguide is configured to be positioned in the focus zone so that the focused acoustic waves are propagated through the medium in the inner lumen of the waveguide.

Abstract: A method of forming an upper for an article of footwear includes depositing a fibrous material over a shoe last to form a fibrous material layer, where the fibrous material layer forms a portion of an upper of the article of footwear, flowing a polymer material within a mold so as to conform with a lower portion of the upper including the fibrous material layer, and drying the polymer material to form a sole structure for the article of footwear.

Abstract: A method of forming an upper for an article of footwear includes providing a first material layer over a shoe last, providing a second material layer over the first material layer such that the first and second material layers adhere to each other at an interface between the first and second material layers, where one or both of the first material layer and second material layer is provided by spray forming a polymer material onto the last. The material layers are removed from the last and turned inside out such that the first material layer includes an exposed surface that forms an exterior surface of the upper.

Abstract: A surgical system includes a steerable instrument. The steerable instrument includes a first tube including a first serpentine beam formed in a tubular sidewall thereof, and a second tube including a second serpentine beam formed in a tubular sidewall thereof. The first and second tubes are concentrically nested and positioned so that the first and second serpentine beams are at least partially aligned with each other axially and face in radial directions that differ angularly from one another. The first and second tubes are connected to each other distally of the first and second serpentine beams. The first and second serpentine beams define a bending segment that is actuatable to form a bend in the nested tube structure in response to differential axial forces applied to the first and second tubes.

Abstract: A method is provided of making an upper for an article of footwear, the method including applying a liquid to select portions of a first substrate sheet of material, applying a powder to the first substrate sheet of material, applying suction to the first substrate sheet of material in order to remove the powder from portions of the first substrate sheet of material that are not coated with the liquid to form a selectively powdered sheet of material, applying additional liquid, additional powder, and additional suction to additional substrate sheets of material to form a stack of selectively powdered sheets of material, using compression and heat to join the stack of selectively powdered sheets of material into a partially cured structure, and removing uncured portions of sheet material from the partially cured structure leaving a cured structure. Different portions of the cured structure can have different properties.

Abstract: A last for forming an upper of an article of footwear includes a first portion including a lateral side and a medial side that opposes the lateral side, and a second portion connected with and extending upward and transversely outward in an angled manner away from the first portion such that a terminal end of the second portion is distanced from the first portion. An exterior surface of the last can include a plurality of three dimensional structural surface components disposed over at least 50% of the exterior surface of the last.

Abstract: A sole structure for an article of footwear includes a transition region between two sole structure layers. The transition region includes a curved portion having a geometry defined by a portion of an ellipse. A plate which includes the curved portion can be provided between the two sole structure layers. The sole structure enhances the roll acceleration of the article of footwear during use.

Abstract: An endoscope device is provided. The device includes a handle, a steerable sheath, disposed on the handle, and a flexible tube. The device further includes a light source and an image sensor disposed on the flexible tube. The handle includes a passage. The steerable sheath includes a tip, a steerable section, and a lumen. The steerable section of the steerable sheath is actuable to form a bend, such that the tip is operable to be steered toward an anatomical region within a patient. The flexible tube is configured to be inserted within the lumen and the inner passage, such that the light source and the image source are positioned at or near the tip of the steerable sheath. The flexible tube is further configured to be removed from the lumen, such that the lumen is operable to aspirate a bodily object from the anatomical region via the tip.

Abstract: A sole structure for an article of footwear includes a transition region between two sole structure layers. The transition region includes a curved portion having a geometry defined by a portion of an ellipse. A plate which includes the curved portion can be provided between the two sole structure layers. The sole structure enhances the roll acceleration of the article of footwear during use.

Abstract: A method is provided of making an upper for an article of footwear, the method including applying a liquid to select portions of a first substrate sheet of material, applying a powder to the first substrate sheet of material, applying suction to the first substrate sheet of material in order to remove the powder from portions of the first substrate sheet of material that are not coated with the liquid to form a selectively powdered sheet of material, applying additional liquid, additional powder, and additional suction to additional substrate sheets of material to form a stack of selectively powdered sheets of material, using compression and heat to join the stack of selectively powdered sheets of material into a partially cured structure, and removing uncured portions of sheet material from the partially cured structure leaving a cured structure. Different portions of the cured structure can have different properties.

Abstract: Various embodiments of an apparatus for measuring binding kinetics of an interaction of an analyte material present in a fluid sample are disclosed. The apparatus includes a sensing resonator having at least one binding site for the analyte material; actuation circuitry adapted to drive the sensing resonator into an oscillating motion; measurement circuitry coupled to the sensing resonator and adapted to measure an output signal of the sensing resonator representing resonance characteristics of the oscillating motion of the sensing resonator; and a controller coupled to the actuation and measurement circuitry, wherein the controller is adapted to detect an individual binding event between the at least one binding site and a molecule of the analyte material.

Abstract: A method is provided of making an upper for an article of footwear, the method including applying a liquid to select portions of a first substrate sheet of material, applying a powder to the first substrate sheet of material, applying suction to the first substrate sheet of material in order to remove the powder from portions of the first substrate sheet of material that are not coated with the liquid to form a selectively powdered sheet of material, applying additional liquid, additional powder, and additional suction to additional substrate sheets of material to form a stack of selectively powdered sheets of material, using compression and heat to join the stack of selectively powdered sheets of material into a partially cured structure, and removing uncured portions of sheet material from the partially cured structure leaving a cured structure. Different portions of the cured structure can have different properties.

Abstract: A sole structure for an article of footwear includes an upper layer formed of a first foam material and a lower layer formed of a second foam material and having a hardness that is greater than a hardness of the upper layer. In addition, a plate can be disposed between the upper layer and the lower layer, where the plate has a hardness that is greater than each of the upper and lower layers.

Abstract: A last for forming an upper of an article of footwear includes a first portion including a lateral side and a medial side that opposes the lateral side, and a second portion connected with and extending upward and transversely outward in an angled manner away from the first portion such that a terminal end of the second portion is distanced from the first portion. An exterior surface of the last can include a plurality of three dimensional structural surface components disposed over at least 50% of the exterior surface of the last.

Abstract: A last for forming an upper of an article of footwear includes an exterior surface, where the exterior surface includes a plurality of three dimensional structural surface components disposed over at least 50% of the exterior surface of the last.

Abstract: A solid mount resonator sensor has a substrate. An anti-reflector stack is disposed proximate the substrate. The anti-reflector stack includes one or more acoustic interference layers. A first electrode is disposed proximate the anti-reflector stack. A second electrode having a first surface facing towards the first electrode and an opposing second surface facing away from the first electrode. A substantially quarter-wave piezoelectric material layer is disposed between the first and second electrodes.

Abstract: Various embodiments of an apparatus for measuring binding kinetics of an interaction of an analyte material present in a fluid sample are disclosed. The apparatus includes a sensing resonator having at least one binding site for the analyte material; actuation circuitry adapted to drive the sensing resonator into an oscillating motion; measurement circuitry coupled to the sensing resonator and adapted to measure an output signal of the sensing resonator representing resonance characteristics of the oscillating motion of the sensing resonator; and a controller coupled to the actuation and measurement circuitry, wherein the controller is adapted to detect an individual binding event between the at least one binding site and a molecule of the analyte material.

Abstract: A method of forming an upper for an article of footwear includes providing a first material layer over a shoe last, providing a second material layer over the first material layer such that the first and second material layers adhere to each other at an interface between the first and second material layers, where one or both of the first material layer and second material layer is provided by spray forming a polymer material onto the last. The material layers are removed from the last and turned inside out such that the first material layer includes an exposed surface that forms an exterior surface of the upper.

Abstract: Various embodiments of an apparatus for measuring binding kinetics of an interaction of an analyte material present in a fluid sample are disclosed. The apparatus includes a sensing resonator having at least one binding site for the analyte material; actuation circuitry adapted to drive the sensing resonator into an oscillating motion; measurement circuitry coupled to the sensing resonator and adapted to measure an output signal of the sensing resonator representing resonance characteristics of the oscillating motion of the sensing resonator; and a controller coupled to the actuation and measurement circuitry, wherein the controller is adapted to detect an individual binding event between the at least one binding site and a molecule of the analyte material.