Abstract: A magnetic field measurement system that includes at least one magnetometer; at least one magnetic field generator; a processor coupled to the at least one magnetometer and the at least one magnetic field generator and configured to: measure an ambient background magnetic field using at least one of the at least one magnetometer in a first mode selected from a scalar mode or a vector mode; generate, in response to the measurement of the ambient background magnetic field, a compensation field using the at least one magnetic field generator; and measure a target magnetic field using at least one of the at least one magnetometer in a spin exchange relaxation free (SERF) mode which is different from the first mode.

Abstract: A magnetic field measurement system for measurement of weak magnetic field signals or a wearable assembly includes at least one magnetometer and a shield disposed around the magnetometer. The shield includes a first portion configured for positioning between the at least one magnetometer and a source of the weak magnetic field signals. The first portion is made of an amplitude-selective magnetic shield (ASMS) that preferentially passes magnetic fields having a magnetic field amplitude below a threshold (for example, 500 nT or less) and shields magnetic fields having a larger magnetic field amplitude.

Abstract: A magnetic field generator includes a first planar substrate, a second planar substrate positioned opposite to the first planar substrate and separated from the first planar substrate by a gap, a first wiring set on the first planar substrate, a second wiring set on the second planar substrate, and one or more interconnects between the first planar substrate and the second planar substrate. The one or more interconnects electrically connect the first wiring set with the second wiring set to form a continuous electrical path. The continuous electrical path forms a conductive winding configured to generate, when supplied with a drive current, a first component of a compensation magnetic field configured to actively shield a magnetic field sensing region located in the gap from ambient background magnetic fields along a first axis that is substantially parallel to the first planar substrate and the second planar substrate.

Abstract: Disclosed herein are devices and methods for modifying a conventional imager to have functional features similar to that of a lock-in camera. Optical mask devices are configured to be coupled to conventional imager sensors and the configuration of the mask devices can be adjusted to acquire image data in rapid succession. One variation of an optical mask device comprises a substrate comprising a pattern of light-blocking and light-transmitting regions and an attachment structure for coupling the optical mask device to the imager. The substrate is configured to adjust the position of the light-blocking regions and light-transmitting regions relative to the light-sensing region of the imager based on a set of one or more predetermined substrate configurations. In some variations, the mask device and/or the imager sensor may be mechanically moved relative to each other based on the set of one or more predetermined substrate configurations.

Abstract: A magnetometer can include a single, integrated, unitary structure that has a gas cell defining a cavity having a vapor or vaporizable material disposed therein, a collimating element coupled to the gas cell and configured for collimating light directed toward the gas cell, and a lens element coupled the gas cell and configured for redirecting at least a portion of light that has passed through the gas cell. Additionally or alternatively, a gas cell of a magnetometer may be made of sapphire.

Abstract: A non-invasive optical detection system and method are provided. Sample light is delivered into a target volume of interest, whereby the sample light is scattered by the target volume of interest, resulting in a sample light pattern that exits the anatomical structure. Reference light is combined with the sample light pattern to generate at least one interference light pattern, each of which may have a time varying interference component that integrates to a first value in the absence of the physiological event, and that integrates to a second greater value in the presence of the physiological event. Intensities of spatial components of each interference light pattern are detected during a measurement period. A function of the detected spatial component intensities of the interference light pattern(s) is analyzed, and a presence of the physiological event in the target volume of interest is determined based on the analysis.

Abstract: An exemplary magnetic field measurement system includes a wearable sensor unit and a single controller. The wearable sensor unit includes a plurality of magnetometers. The single controller is configured to generate a single clock signal and use the single clock signal to drive one or more components within the magnetometers.

Abstract: An exemplary controller may include a single clock source configured to generate a single clock signal used to drive one or more components within a plurality of magnetometers and a plurality of differential signal measurement circuits configured to measure current output by a photodetector of each of the plurality of magnetometers.

Abstract: An exemplary magnetic field measurement system includes a wearable sensor unit that includes a magnetometer and a twisted pair cable interface assembly electrically connected to the magnetometer.

Abstract: A system for training a neurome that emulates a brain of a user comprises a non-invasive brain interface assembly configured for detecting neural activity of the user in response to analog instances of a plurality of stimuli peripherally input into the brain of the user from at least one source of content, memory configured for storing a neurome configured for outputting a plurality of determined brain states of an avatar in response to inputs of the digital instances of the plurality of stimuli, and a neurome training processor configured for determining a plurality of brain states of the user based on the detected neural activity of the user, and modifying the neurome based on the plurality of determined brain states of the user and the plurality of determined brain states of the avatar.

Abstract: A magnetic field recording system includes a headgear to be placed on a user; optically pumped magnetometers (OPMs) disposed in or on the headgear to detect magnetic fields; at least two sensing modalities selected from the following: i) a magnetic sensing modality, ii) an optical sensing modality, or iii) an inertial sensing modality; and a tracking unit configured to receive, from each of the at least two sensing modalities, a corresponding magnetic data stream, optical data stream, or inertial data stream and to track a position or orientation of the headgear or user; and a system controller configured to control operation of the OPMs and to receive, from the tracking unit, the position or orientation of the headgear or user.

Abstract: A magnetocardiography (MCG) system includes a passively shielded enclosure having walls defining the passively shielded enclosure, each of the walls including passive magnetic shielding material to reduce an ambient background magnetic field within the passively shielded enclosure; an MCG measurement device including optically pumped magnetometers (OPMs); and active shield coils within the passively shielded enclosure and stationary relative to the passively shielded enclosure and the MCG measurement device, wherein the active shield coils are configured to further reduce the ambient background magnetic field within a user area of the passively shielded enclosure.

Abstract: A magnetic field recording system includes a headgear for a user; optically pumped magnetometers (OPMs) disposed in or on the headgear to detect magnetic fields and, in response to the detection, produce magnetic field data; at least one sensing modality including an optical sensing modality having at least one light source and at least one camera or light detector to receive light reflected or directed from the user and to produce an optical data stream; a tracking unit to receive the optical data stream and track a position or orientation of the headgear or user; a system controller to control operation of the OPMs and receive, from the tracking unit, the position or orientation of the headgear or user; and a processor to receive the optical data stream and the magnetic field data from the OPMs and analyze the magnetic field data using the optical data stream for validation.

Abstract: A shielding arrangement for a magnetoencephalography (MEG) system includes a passively shielded enclosure having a plurality of walls defining the passively shielded enclosure, each of the plurality of walls including passive magnetic shielding material to reduce an ambient background magnetic field within the passively shielded enclosure; a vestibular wall extending from a first vertical wall to define, and at least partially separate, a vestibular area of the passively shielded enclosure adjacent the doorway and a user area of the passively shielded enclosure; and active shield coils distributed within the passively shielded enclosure and configured to further reduce the ambient background magnetic field within the user area of the passively shielded enclosure.

Abstract: A system for use in managing a neuromodulation therapy includes an ultrasound transducer array controlled by a control unit to deliver ultrasound waveforms for causing modulation of neural tissue in a patient. The system acquires data indicating a response to the modulation, analyzes the acquired data to determine correlation data between a response to the modulation and an ultrasound control parameter, and reports the correlation data to enable identification of at least one therapy parameter to be used to deliver a neuromodulation therapy to the patient by a therapy delivery system.

Abstract: An exemplary magnetic field measurement system includes a wearable sensor unit and a controller. The wearable sensor unit includes 1) a magnetometer comprising a photodetector and 2) a magnetic field generator configured to generate a compensation magnetic field configured to actively shield the magnetometer from ambient background magnetic fields. The controller is configured to interface with the magnetometer and the magnetic field generator and includes a differential signal measurement circuit configured to measure current output by the photodetector.

Abstract: An exemplary magnetic field measurement system includes a wearable sensor unit and a single controller. The wearable sensor unit includes a plurality of magnetometers and a magnetic field generator configured to generate a compensation magnetic field configured to actively shield the magnetometers from ambient background magnetic fields. The single controller is configured to interface with the magnetometers and the magnetic field generator.

Abstract: An exemplary magnetic field measurement system includes a wearable sensor unit that includes a magnetometer, a magnetic field generator configured to generate a compensation magnetic field configured to actively shield the magnetometer from ambient background magnetic fields, a twisted pair cable interface assembly electrically connected to the magnetometer, and a coaxial cable interface assembly electrically connected to the magnetic field generator.

Abstract: A system for training a neurome that emulates a brain of a user comprises a non-invasive brain interface assembly configured for detecting neural activity of the user in response to analog instances of a plurality of stimuli peripherally input into the brain of the user from at least one source of content, memory configured for storing a neurome configured for outputting a plurality of determined brain states of an avatar in response to inputs of the digital instances of the plurality of stimuli, and a neurome training processor configured for determining a plurality of brain states of the user based on the detected neural activity of the user, and modifying the neurome based on the plurality of determined brain states of the user and the plurality of determined brain states of the avatar.

Abstract: An authentication system comprises a brain-computer interface (BCI) configured for detecting neural activity in a brain of a subject in response to the subject performing a repeatable mental task, and outputting neural data representative of the detected neural activity. The authentication system further comprises a computer configured for acquiring the neural data output by the BCI while the subject is performing the repeatable mental task, and generating an authorization request containing the neural data. The authentication system further comprises an authentication processor configured for acquiring the authorization request containing the neural data from the computer, authenticating the subject based on the acquired authorization request, and sending an authorization token to the computer.