Patents by Inventor Jan Berka

Jan Berka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNE PROFILING BY PRIMER EXTENSION TARGET ENRICHMENT
    Publication number: 20240125007
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Application
    Filed: December 29, 2023
    Publication date: April 18, 2024
    Inventors: Jan BERKA, Carolina DALLETT, Richard DANNEBAUM, Brian GODWIN, Seoyoung KIM, Jainee LEWIS, Khai LUONG, Sedide OZTURK, Joseph PLATZER, Florian RUBELT, Dilduz TELMAN
  • Immuno-PETE
    Publication number: 20240102203
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Application
    Filed: June 28, 2023
    Publication date: March 28, 2024
    Inventors: Jan BERKA, Brian GODWIN, Carolina DALLETT, Sedide OZTURK, Joseph PLATZER, Seoyoung KIM
  • IMMUNE PROFILING BY PRIMER EXTENSION TARGET ENRICHMENT
    Publication number: 20240026570
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Application
    Filed: August 14, 2023
    Publication date: January 25, 2024
    Inventors: Jan BERKA, Carolina DALLETT, Richard DANNEBAUM, Brian GODWIN, Seoyoung KIM, Jainee LEWIS, Khai LUONG, Sedide OZTURK, Joseph PLATZER, Florian RUBELT, Dilduz TELMAN
  • DEVICES FOR SAMPLE ANALYSIS USING EPITACHOPHORESIS
    Publication number: 20230356211
    Abstract: The present disclosure generally relates to devices and methods for effecting epitachophoresis. Epitachophoresis may be used to effect sample analysis, such as by selective separation, detection, extraction, and/or pre-concentration of target analytes such as, for example, DNA, RNA, and/or other biological molecules. Said target analytes may be collected following epitachophoresis and used for desired downstream applications and further analysis.
    Type: Application
    Filed: May 15, 2023
    Publication date: November 9, 2023
    Inventors: Yann ASTIER, Jan BERKA, Ulrich SCHLECHT, Frantisek FORET, Vladimira DATINSKA, Ivona VORACOVA
  • SPATIAL ANALYSIS OF MULTIPLE TARGETS IN TISSUE SAMPLES
    Publication number: 20230340578
    Abstract: The invention provides methods and compositions for analysis of single cell in tissue sample allowing for simultaneous detection and localization of multiple targets in the cells.
    Type: Application
    Filed: July 8, 2021
    Publication date: October 26, 2023
    Inventors: Jan BERKA, Dieter HEINDL, Sedide OZTURK, Nikolaus-Peter STENGELE
  • Immune profiling by primer extension target enrichment
    Patent number: 11773511
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Grant
    Filed: August 18, 2020
    Date of Patent: October 3, 2023
    Assignee: Roche Sequencing Solutions, Inc.
    Inventors: Jan Berka, Carolina Dallett, Richard Dannebaum, Brian Godwin, Seoyoung Kim, Jainee Lewis, Khai Luong, Sedide Ozturk, Joseph Platzer, Florian Rubelt, Dilduz Telman
  • Immuno-PETE
    Patent number: 11725307
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Grant
    Filed: May 4, 2021
    Date of Patent: August 15, 2023
    Assignee: Roche Sequencing Solutions, Inc.
    Inventors: Jan Berka, Brian Godwin, Carolina Dallett, Sedide Ozturk, Joseph Platzer, Seoyoung Kim
  • Devices for sample analysis using epitachophoresis
    Patent number: 11691141
    Abstract: The present disclosure generally relates to devices for effecting epitachophoresis. Epitachophoresis may be used to effect sample analysis, such as by selective separation, detection, extraction, and/or pre-concentration of target analytes such as, for example, DNA, RNA, and/or other biological molecules. Said target analytes may be collected following epitachophoresis and used for desired downstream applications and further analysis.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: July 4, 2023
    Assignee: Roche Sequencing Solutions, Inc.
    Inventors: Yann Astier, Jan Berka, Ulrich Schlecht, Frantisek Foret, Vladimira Datinska, Ivona Voracova
  • SAMPLE COLLECTION TRAY FOR MULTI-WELL PLATES
    Publication number: 20230166259
    Abstract: The invention is a device for quantitatively collecting pooled samples from multiwell plates.
    Type: Application
    Filed: April 29, 2021
    Publication date: June 1, 2023
    Inventor: Jan BERKA
  • System for identification of antigens recognized by T cell receptors expressed on tumor infiltrating lymphocytes
    Patent number: 11603565
    Abstract: The invention is a method of identifying a cognate antigen for a T-cell receptor using neoantigens from a patient's tumor cells combined with the patient's T-cells and using cell sorting, genome sequencing, expressing TCR genes, presenting tumor neoantigens on MHC complex and uniquely barcoding the T-cells where TCR recognition occurs to tag all components of the TCR recognition complex.
    Type: Grant
    Filed: June 14, 2019
    Date of Patent: March 14, 2023
    Assignees: ROCHE SEQUENCING SOLUTIONS, INC., VENTANA MEDICAL SYSTEMS, INC.
    Inventors: Nelson R. Alexander, Aoune Barhoumi, Jan Berka, Rui Chen, Lisa L. Gallegos, Toumy Guettouche, Seoyoung Kim, Maeve E. O'Huallachain, Sedide Ozturk, Jigar Patel, Florian Rubelt, Stacey Stanislaw
  • IMMUNE REPERTOIRE PROFILING BY PRIMER EXTENSION TARGET ENRICHMENT
    Publication number: 20220372566
    Abstract: The invention is a method of assessing a mammalian immune repertoire by primer extension target enrichment (PETE). Methods and compositions for assessing an immune repertoire and the status of additional genetic markers are disclosed.
    Type: Application
    Filed: September 16, 2020
    Publication date: November 24, 2022
    Inventors: Jan Berka, Richard Dannebaum, Brian Godwin, Joseph Platzer
  • Immuno-PETE
    Patent number: 11306356
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: April 19, 2022
    Assignee: Roche Sequencing Solutions, Inc.
    Inventors: Jan Berka, Brian Godwin, Carolina Dallett, Sedide Ozturk, Joseph Platzer, Seoyoung Kim
  • A SYSTEM FOR IDENTIFICATION OF ANTIGENS RECOGNIZED BY T CELL RECEPTORS EXPRESSED ON TUMOR INFILTRATING LYMPHOCYTES
    Publication number: 20210285049
    Abstract: The invention is a method of identifying a cognate antigen for a T-cell receptor using neoantigens from a patient's tumor cells combined with the patient's T-cells and using cell sorting, genome sequencing, expressing TCR genes, presenting tumor neoantigens on MHC complex and uniquely barcoding the T-cells where TCR recognition occurs to tag all components of the TCR recognition complex.
    Type: Application
    Filed: June 14, 2019
    Publication date: September 16, 2021
    Inventors: Nelson R. Alexander, Aoune Barhoumi, Jan Berka, Rui Chen, Lisa L. Gallegos, Toumy Guettouche, Seoyoung Kim, Maeve E. O'Huallachain, Sedide Ozturk, Jigar Patel, Florian Rubelt, Stacey Stanislaw
  • Immuno-PETE
    Patent number: 11098360
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: August 24, 2021
    Assignee: Roche Sequencing Solutions, Inc.
    Inventors: Jan Berka, Brian Godwin, Carolina Dallett, Sedide Ozturk, Joseph Platzer, Seoyoung Kim
  • Immuno-PETE
    Publication number: 20210254157
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Application
    Filed: May 4, 2021
    Publication date: August 19, 2021
    Inventors: Jan BERKA, Brian GODWIN, Carolina DALLETT, Sedide OZTURK, Joseph PLATZER, Seoyoung KIM
  • IMMUNE PROFILING BY PRIMER EXTENSION TARGET ENRICHMENT
    Publication number: 20210172015
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Application
    Filed: August 18, 2020
    Publication date: June 10, 2021
    Inventors: Jan Berka, Carolina Dallett, Richard Dannebaum, Brian Godwin, Seoyoung Kim, Jainee Lewis, Khai Luong, Sedide Ozturk, Joseph Platzer, Florian Rubelt, Dilduz Telman
  • Bead emulsion nucleic acid amplification
    Patent number: 10982274
    Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.
    Type: Grant
    Filed: January 16, 2019
    Date of Patent: April 20, 2021
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Jan Berka, Yi-Ju Chen, John H. Leamon, Steven Lefkowitz, Kenton L. Lohman, Vinod B. Makhijani, Jonathan M. Rothberg, Gary J. Sarkis, Maithreyan Srinivasan, Michael P. Weiner
  • Immuno-PETE
    Publication number: 20200385707
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Application
    Filed: June 1, 2017
    Publication date: December 10, 2020
    Inventors: Jan BERKA, Brian GODWIN, Carolina DALLETT, Sedide OZTURK, Joseph PLATZER, Seoyoung KIM
  • Sample collection sump tray for multiwell plates
    Patent number: D954992
    Type: Grant
    Filed: May 1, 2020
    Date of Patent: June 14, 2022
    Assignee: Roche Sequencing Solutions, Inc.
    Inventor: Jan Berka
  • Sample collection sump tray for multiwell plates
    Patent number: D959697
    Type: Grant
    Filed: November 19, 2021
    Date of Patent: August 2, 2022
    Assignee: Roche Sequencing Solutions, Inc.
    Inventor: Jan Berka