Patents by Inventor Jan Berka

Jan Berka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8748102
    Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.
    Type: Grant
    Filed: February 23, 2011
    Date of Patent: June 10, 2014
    Assignee: 454 Life Sciences Corporation
    Inventors: Jan Berka, Yi-Ju Chen, John H. Leamon, Steve Lefkowitz, Kenton L. Lohman, Vinod B. Makhijani, Jonathan M. Rothberg, Gary J. Sarkis, Maithreyan Srinivasan, Michael P. Weiner
  • Publication number: 20140122181
    Abstract: A demand response system having an improved load forecaster connected to a decision engine. A basis of the improved forecaster may be an introduction of an explanatory variable which is a time-based shaping function that allows capturing a demand response (DR) lead and DR rebound effect, and the like, capturing a shape of load reduction, given by an applied DR action. The engine may receive information from the forecaster and utility relative to behavior of a DR customer, market price, renewable energy generation, grid status, and so on. The engine may provide optimal timing, selection of resources, and so forth, to a DR automation server, which in turn may provide DR signals to customers. The customers may provide data consumption data to a database. Electricity generation data may also be provided to the database. Selected relevant data from the database and weather information may go to the load forecaster.
    Type: Application
    Filed: January 7, 2014
    Publication date: May 1, 2014
    Applicant: Honeywell International Inc.
    Inventors: Radek Fisera, Jan Berka, Jiri Rojicek
  • Publication number: 20130078638
    Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the heads. Also disclosed are kits and apparatuses for performing the methods of the invention.
    Type: Application
    Filed: September 14, 2012
    Publication date: March 28, 2013
    Inventors: Jan Berka, Yi-Ju Chen, John H. Leamon, Steve Lefkowitz, Kenton L. Lohman, Vinod B. Makhijani, Jonathan M. Rothberg, Gary J. Sarkis, Maithreyan Srinivasan, Michael P. Weiner
  • Patent number: 8012690
    Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: September 6, 2011
    Assignee: 454 Life Sciences Corporation
    Inventors: Jan Berka, Yi-Ju Chen, John H. Leamon, Steve Lefkowitz, Kenton L. Lohman, Vinod B. Makhijani, Jonathan M. Rothberg, Gary J. Sarkis, Maithreyan Srinivasan, Michael P. Weiner
  • Publication number: 20110201526
    Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.
    Type: Application
    Filed: February 23, 2011
    Publication date: August 18, 2011
    Inventors: Jan Berka, Yi-Ju Chen, John H. Leamon, Steve Lefkowitz, Kenton L. Lohman, Vinod B. Makhijani, Johathan M. Rothberg, Gary J. Sarkis, Maithreyan Srinivasan, Michael P. Weiner
  • Patent number: 7842457
    Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.
    Type: Grant
    Filed: January 28, 2004
    Date of Patent: November 30, 2010
    Assignee: 454 Life Sciences Corporation
    Inventors: Jan Berka, Yi-Ju Chen, John H. Leamon, Steve Lefkowitz, Kenton L. Lohman, Vinod B. Makhijani, Jonathan M. Rothberg, Gary J. Sarkis, Maithreyan Srinivasan, Michael P. Weiner
  • Patent number: 7601499
    Abstract: The present invention provides for a method of preparing a target nucleic acid fragments to produce a smaller nucleic acid which comprises the two ends of the target nucleic acid. Specifically, the invention provides cloning and DNA manipulation strategies to isolate the two ends of a large target nucleic acid into a single small DNA construct for rapid cloning, sequencing, or amplification.
    Type: Grant
    Filed: June 6, 2006
    Date of Patent: October 13, 2009
    Assignee: 454 Life Sciences Corporation
    Inventors: Jan Berka, Zhoutao Chen, Michael Egholm, Brian C. Godwin, Stephen Kyle Hutchison, John Harris Leamon, Gary James Sarkis, Jan Fredrik Simons
  • Publication number: 20080132693
    Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.
    Type: Application
    Filed: October 31, 2007
    Publication date: June 5, 2008
    Inventors: Jan Berka, Yi-Ju Chen, John H. Leamon, Steve Lefkowitz, Kenton L. Lohman, Vinod B. Makhijani, Jonathan M. Rothberg, Gary J. Sarkis, Maithreyan Srinivasan, Michael P. Weiner
  • Patent number: 7335762
    Abstract: Disclosed herein are methods and apparatuses for sequencing a nucleic acid. These methods permit a very large number of independent sequencing reactions to be arrayed in parallel, permitting simultaneous sequencing of a very large number (>10,000) of different oligonucleotides.
    Type: Grant
    Filed: August 15, 2002
    Date of Patent: February 26, 2008
    Assignee: 454 Life Sciences Corporation
    Inventors: Jonathan M. Rothberg, Joel S. Bader, Scott B. Dewell, Keith McDade, John W. Simpson, Jan Berka, Christopher M. Colangelo, Michael P. Weiner
  • Patent number: 7264929
    Abstract: Disclosed herein are methods and apparatuses for sequencing a nucleic acid. These methods permit a very large number of independent sequencing reactions to be arrayed in parallel, permitting simultaneous sequencing of a very large number (>10,000) of different oligonucleotides.
    Type: Grant
    Filed: November 19, 2002
    Date of Patent: September 4, 2007
    Assignee: 454 Life Sciences Corporation
    Inventors: Jonathan M. Rothberg, Joel S. Bader, Scott B. Dewell, Keith McDade, John W. Simpson, Jan Berka, Christopher M. Colangelo
  • Patent number: 7244559
    Abstract: Disclosed herein are methods and apparatuses for sequencing a nucleic acid. These methods permit a very large number of independent sequencing reactions to be arrayed in parallel, permitting simultaneous sequencing of a very large number (>10,000) of different oligonucleotides.
    Type: Grant
    Filed: March 21, 2001
    Date of Patent: July 17, 2007
    Assignee: 454 Life Sciences Corporation
    Inventors: Jonathan M. Rothberg, Joel S. Bader, Scott B. Dewell, Keith McDade, John W. Simpson, Jan Berka, Christopher M. Colangelo
  • Patent number: 7211390
    Abstract: Disclosed herein are methods and apparatuses for sequencing a nucleic acid. In one aspect, the method includes annealing a population of circular nucleic acid molecules to a plurality of anchor primers linked to a solid support, and amplifying those members of the population of circular nucleic acid molecules which anneal to the target nucleic acid, and then sequencing the amplified molecules by detecting the presence of a sequence byproduct such as pyrophosphate.
    Type: Grant
    Filed: February 26, 2004
    Date of Patent: May 1, 2007
    Assignee: 454 Life Sciences Corporation
    Inventors: Jonathan M. Rothberg, Joel S. Bader, Scott B. Dewell, Keith McDade, John W. Simpson, Jan Berka, Christopher M. Colangelo
  • Publication number: 20070092872
    Abstract: Disclosed herein are methods and apparatuses for sequencing a nucleic acid. These methods permit a very large number of independent sequencing reactions to be arrayed in parallel, permitting simultaneous sequencing of a very large number (>10,000) of different oligonucleotides.
    Type: Application
    Filed: August 15, 2002
    Publication date: April 26, 2007
    Inventors: Jonathan Rothberg, Joel Bader, Scott Dewell, Keith McDade, John Simpson, Jan Berka, Christopher Colangelo, Michael Weiner
  • Publication number: 20060292611
    Abstract: The present invention provides for a method of preparing a target nucleic acid fragments to produce a smaller nucleic acid which comprises the two ends of the target nucleic acid. Specifically, the invention provides cloning and DNA manipulation strategies to isolate the two ends of a large target nucleic acid into a single small DNA construct for rapid cloning, sequencing, or amplification.
    Type: Application
    Filed: June 6, 2006
    Publication date: December 28, 2006
    Inventors: Jan Berka, Zhoutao Chen, Michael Egholm, Brian Godwin, Stephen Hutchison, John Leamon, Gary Sarkis, Jan Simons
  • Publication number: 20050079510
    Abstract: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.
    Type: Application
    Filed: January 28, 2004
    Publication date: April 14, 2005
    Inventors: Jan Berka, Yi-Ju Chen, John Leamon, Steve Lefkowitz, Kenton Lohman, Vinod Makhijani, Jonathan Rothberg, Gary Sarkis, Maithreyan Srinivasan, Michael Weiner
  • Publication number: 20040248161
    Abstract: Disclosed herein are methods and apparatuses for sequencing a nucleic acid. In one aspect, the method includes annealing a population of circular nucleic acid molecules to a plurality of anchor primers linked to a solid support, and amplifying those members of the population of circular nucleic acid molecules which anneal to the target nucleic acid, and then sequencing the amplified molecules by detecting the presence of a sequence byproduct such as pyrophosphate.
    Type: Application
    Filed: February 26, 2004
    Publication date: December 9, 2004
    Inventors: Jonathan M. Rothberg, Joel S. Bader, Scott B. Dewell, Keith McDade, John W. Simpson, Jan Berka, Christopher M. Colangelo
  • Publication number: 20030148344
    Abstract: Disclosed herein are methods and apparatuses for sequencing a nucleic acid. These methods permit a very large number of independent sequencing reactions to be arrayed in parallel, permitting simultaneous sequencing of a very large number (>10,000) of different oligonucleotides.
    Type: Application
    Filed: November 19, 2002
    Publication date: August 7, 2003
    Inventors: Jonathan M. Rothberg, Joel S. Bader, Scott B. Dewell, Keith McDade, John W. Simpson, Jan Berka, Christopher M. Colangelo
  • Publication number: 20030100102
    Abstract: Disclosed herein are methods and apparatuses for sequencing a nucleic acid. These methods permit a very large number of independent sequencing reactions to be arrayed in parallel, permitting simultaneous sequencing of a very large number (>10,000) of different oligonucleotides.
    Type: Application
    Filed: August 15, 2002
    Publication date: May 29, 2003
    Inventors: Jonathan M. Rothberg, Joel S. Bader, Scott B. Dewell, Keith McDade, John W. Simpson, Jan Berka, Christopher M. Colangelo, Michael P. Weiner
  • Patent number: 6554985
    Abstract: This invention relates to methods and formulations for the separation of biological macromolecules according to their size using capillary electrophoresis with improved polyacrylamide matrixes under denaturing conditions.
    Type: Grant
    Filed: August 13, 1999
    Date of Patent: April 29, 2003
    Assignee: CuraGen Corporation
    Inventors: Marie C. Ruiz-Martinez, Jan Berka, John W. Simpson
  • Publication number: 20030068629
    Abstract: Disclosed herein are methods and apparatuses for sequencing a nucleic acid. These methods permit a very large number of independent sequencing reactions to be arrayed in parallel, permitting simultaneous sequencing of a very large number (>10,000) of different oligonucleotides.
    Type: Application
    Filed: March 21, 2002
    Publication date: April 10, 2003
    Inventors: Jonathan M. Rothberg, Joel S. Bader, Scott B. Dewell, Keith McDade, John W. Simpson, Jan Berka, Christopher M. Colangelo, Michael P. Weiner