Abstract: The invention concerns a drilling device (1) and a method for drilling holes in a stack of material (100). The drilling device is provided with clamping means (23, 26) for clamping the material, a hollow drill (10) with an internal channel and a drive (3) for the hollow drill. The drilling device is further provided with connecting means (4) for cooling means, that are arranged for conducting gas through the internal channel, and suction means (51) for suctioning drilling debris. The drilling shaft is provided with a cut out, that runs in longitudinal direction along the drill shaft and forms a discharge channel for the drilling debris. The invention also concerns a machine for machining and assembling window coverings, such as pleated blinds, comprising one or more drilling devices according to the invention.

Abstract: A method for processing natural or synthetic leather by using super-critical CO2. The leather can be dried leather, low grade leathers, thin leather, crust leathers, finished leathers, wet blue leathers, and tanned leather, as well as synthetic leather. In a second aspect the invention relates to leather obtained by said method, and in a third aspect to a stand-alone apparatus for performing said method.

Abstract: The invention relates to a system (1) for counting corrugations in a flexible material (100). The system is provided with a carrier (10) with a measuring area (12) and with aligning means (14) for aligning the flexible material in the measuring area, a light source for illuminating the measuring area, a camera for making one or more image recordings of the measuring area and a processor (23), which is arranged for counting the number of corrugations in one or more of the image recordings. The invention also relates to a method for counting a desired number of corrugations in a flexible material, for example pleats in fabric for a window covering, such as a pleated curtain. The invention furthermore relates to a computer program comprising instructions for carrying out the steps of the method.

Abstract: The invention provides a method for extraction of at least one extract compound from a material, comprising: a. contacting carbon dioxide with the material to dissolve an amount of the at least one extract compound from the material into the carbon dioxide; b. contacting the carbon dioxide comprising the at least dissolved extract compound with a sorbent to sorb the at least one extract compound onto the sorbent and for regenerating the carbon dioxide; c. recirculating the regenerated carbon dioxide; and d. repeating said recirculating at a constant density of said carbon dioxide of between 100 and 1000 kg/m3, and repeating said recirculating for at least 10 cycles.

Abstract: An operating device for a screen comprises: a first operating mechanism with a first operating element which is connected to a first movement transfer element connected by means of a first transmission to a drive element for a screen shaft. The first operating mechanism is configured to convert a linear movement of the first operating element to a rotational movement of the drive element for operating the screen shaft in a first rotational direction. The operating device further comprises a second operating mechanism comprising a second operating element which is connected to a second movement transfer element connected by means of a second transmission to the drive element. The second operating mechanism is configured to convert a linear movement of the second operating element to a rotational movement of the drive element for operating the screen shaft in a second rotational direction opposite to the first rotational direction.

Abstract: The invention relates to a spring operated roller blind system, wherein the roller blind (1) comprises an adjusting mechanism (30) for adjusting an end position of the flexible sheet member. The adjusting mechanism comprises a spindle (36) and a connecting member (31) that is connected to the roller shaft for rotation around the spindle. The adjusting mechanism further comprises a first bearing (7) for the roller shaft that defines a first end position for the connecting member (31). At least one of the bracket connectors (21) comprises a pin (33) for detachable mounting in a cooperating recess (35) on the adjusting mechanism, wherein the pin and the recess have an unround cross section.

Abstract: The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme including the capability of reducing 5-((4S)-2-oxo-4-phenyl (1,3-oxazolidin-3-yl))-1-(4-fluorophenyl) pentane-1,5-dione to (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize the intermediate (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one in a process for making Ezetimibe.

Abstract: The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme including the capability of reducing 5-((4S)-2-oxo-4-phenyl (1,3-oxazolidin-3-yl))-1-(4-fluorophenyl) pentane-1,5-dione to (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize the intermediate (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one in a process for making Ezetimibe.

Abstract: The invention relates to an operating device (1) for a screen, comprising: a first operating mechanism with a first operating element (7) which is connected to a first movement transfer element connected by means of a first transmission to a drive element (60) for a screen shaft. The first operating mechanism is configured to convert a linear movement of the first operating element to a rotational movement of the drive element for operating the screen shaft in a first rotational direction (R). The operating device (1) further comprises a second operating mechanism comprising a second operating element (8) which is connected to a second movement transfer element connected by means of a second transmission to the drive element (60). The second operating mechanism is configured to convert a linear movement of the second operating element to a rotational movement of the drive element for operating the screen shaft in a second rotational direction (L) opposite to the first rotational direction.

Abstract: A motorized drive of a window covering provided with a device for manually operating the motorized drive comprising a housing to be attached to the window covering with a pull cord and a push button for manual operation. A switch converts pulling movements on the pull cord into first electrical signals for the motorized drive. Controls are configured to save a setting value associated with a current position of the window covering in a data memory after receiving second electrical signals from the push button. A method for saving setting values associated with different positions of the window covering provided with the motorized drive comprising the steps of saving a current position by manual operation of the pull cord and/or the push button.

Abstract: The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme including the capability of reducing 5-((4S)-2-oxo-4-phenyl (1,3-oxazolidin-3-yl))-1-(4-fluorophenyl) pentane-1,5-dione to (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize the intermediate (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one in a process for making Ezetimibe.

Abstract: The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme including the capability of reducing 5-((4S)-2-oxo-4-phenyl (1,3-oxazolidin-3-yl))-1-(4-fluorophenyl) pentane-1,5-dione to (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize the intermediate (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one in a process for making Ezetimibe.

Abstract: A roller blind system, comprising a roller blind having a roller shaft through which a central rod extends and to which a flexible sheet member is attached. The roller blind is provided with two bracket connectors arranged for releasable coupling to mounting brackets. The roller blind is spring operated and comprises a tension spring fixedly connected to the central rod and to the roller shaft and a tension adjusting mechanism for adjusting the tension of the tension spring. The tension adjusting mechanism comprises an adjusting wheel and an adjusting spring for adjusting the rotational position of the central rod, a first bush part arranged on the adjusting wheel for pushing the adjusting spring in a relaxed configuration and a second bush part connected to the central rod for pushing the adjusting spring in a tightened configuration.

Abstract: A process for producing non-surface modified nanocellulose particles in the form of a powder, comprising the steps of i. providing a suspension of never-dried, non-surface modified nanocellulose particles in an aqueous liquid, which is non-solubilising for the non-surface modified nanocellulose particles, and which is water or an aqueous solution of morpholine or piperidine or mixtures thereof, ii. contacting the suspension of non-surface modified nanocellulose particles with a fluid in a supercritical state, which fluid is miscible with the aqueous liquid and is non-solubilising for the non-surface modified nanocellulose particles, under conditions suitable for the transfer of the aqueous liquid into the fluid in a supercritical state, iii. removing the aqueous liquid and the fluid in a supercritical state by controlling pressure and/or temperature, to form the non-surface modified nanocellulose particles, and iv.

Abstract: The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme including the capability of reducing 5-((4S)-2-oxo-4-phenyl (1,3-oxazolidin-3-yl))-1-(4-fluorophenyl) pentane-1,5-dione to (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize the intermediate (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one in a process for making Ezetimibe.

Abstract: The invention relates to a spring operated roller blind system, wherein the roller blind (1) comprises an adjusting mechanism (30) for adjusting an end position of the flexible sheet member. The adjusting mechanism comprises a spindle (36) and a connecting member (31) that is connected to the roller shaft for rotation around the spindle. The adjusting mechanism further comprises a first bearing (7) for the roller shaft that defines a first end position for the connecting member (31). At least one of the bracket connectors (21) comprises a pin (33) for detachable mounting in a cooperating recess (35) on the adjusting mechanism, wherein the pin and the recess have an unround cross section.

Abstract: The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme including the capability of reducing 5-((4S)-2-oxo-4-phenyl (1,3-oxazolidin-3-yl))-1-(4-fluorophenyl) pentane-1,5-dione to (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize the intermediate (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one in a process for making Ezetimibe.

Abstract: The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme including the capability of reducing 5-((4S)-2-oxo-4-phenyl (1,3-oxazolidin-3-yl))-1-(4-fluorophenyl) pentane-1,5-dione to (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize the intermediate (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one in a process for making Ezetimibe.

Abstract: A wind power installation in which conduits through which a cooling medium flows are passed from the interior of the wind power installation through the tower wall or through the foundation outwardly, and the cooling conduits in the heat exchanger bear externally against the tower or are arranged there and are arranged between the tower wall and a cover of the wall of the cooling system.

Abstract: The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme including the capability of reducing 5-((4S)-2-oxo-4-phenyl (1,3-oxazolidin-3-yl))-1-(4-fluorophenyl) pentane-1,5-dione to (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize the intermediate (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one in a process for making Ezetimibe.