Abstract: The present invention relates to a device for mounting a shaft of a screen, such as a window covering, on a surface such as a wall, window frame or a ceiling, wherein the device comprises a mounting bracket and a shaft holder, wherein the mounting bracket is configured for mounting on the surface and the shaft holder is attachable to the mounting bracket, wherein the shaft holder is provided with coupling means for coupling the shaft and the shaft holder in releasably attachable manner to the mounting bracket.

Abstract: The invention relates to an operating device (1) for a screen, comprising: a first operating mechanism with a first operating element (7) which is connected to a first movement transfer element connected by means of a first transmission to a drive element (60) for a screen shaft. The first operating mechanism is configured to convert a linear movement of the first operating element to a rotational movement of the drive element for operating the screen shaft in a first rotational direction (R). The operating device (1) further comprises a second operating mechanism comprising a second operating element (8) which is connected to a second movement transfer element connected by means of a second transmission to the drive element (60). The second operating mechanism is configured to convert a linear movement of the second operating element to a rotational movement of the drive element for operating the screen shaft in a second rotational direction (L) opposite to the first rotational direction.

Abstract: The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme including the capability of reducing 5-((4S)-2-oxo-4-phenyl (1,3-oxazolidin-3-yl))-1-(4-fluorophenyl) pentane-1,5-dione to (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize the intermediate (4S)-3-[(5S)-5 -(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one in a process for making Ezetimibe.

Abstract: The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme including the capability of reducing 5-((4S)-2-oxo-4-phenyl (1,3-oxazolidin-3-yl))-1-(4-fluorophenyl) pentane-1,5-dione to (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize the intermediate (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one in a process for making Ezetimibe.

Abstract: The invention relates to a device (1) for manually operating a motorized drive of a screen, such as a window covering. A housing (2) to be attached to the screen comprises first operating means (3) and second operating means (20) for manual operation of the device. Switching means (10) convert pulling movements on the first operating means into first electrical signals for the motorized drive. Control means (4) are configured to save a setting value associated with a current position of the screen in memory means after receiving second electrical signals from the second operating means (20). The invention likewise relates to a method for saving setting values associated with different positions of a screen, such as a window covering, which screen is provided with a motorized drive and a device according to the invention, comprising the step of saving a current position by manual operation of the first or second operating means.

Abstract: A roller blind system including a roller blind (1) having a roller shaft (4) through which a central rod (6) extends and to which a flexible sheet member is attached. The roller blind is provided with two bracket connectors (21) arranged for releasable coupling to mounting brackets (20). The roller blind is spring operated and includes a tension spring (5) fixedly connected to the central rod and to the roller shaft and a tension adjusting mechanism (10) for adjusting the tension of the tension spring. The tension adjusting mechanism includes an adjusting wheel (11) and an adjusting spring (15) for adjusting the rotational position of the central rod, first engaging means (13) arranged on the adjusting wheel for pushing the adjusting spring in a relaxed configuration and second engaging means (18) connected to the central rod for pushing the adjusting spring in a tightened configuration.

Abstract: The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme including the capability of reducing 5-((4S)-2-oxo-4-phenyl (1,3-oxazolidin-3-yl))-1-(4-fluorophenyl) pentane-1,5-dione to (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize the intermediate (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one in a process for making Ezetimibe.

Abstract: The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme including the capability of reducing 5-((4S)-2-oxo-4-phenyl (1,3-oxazolidin-3-yl))-1-(4-fluorophenyl) pentane-1,5-dione to (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize the intermediate (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one in a process for making Ezetimibe.

Abstract: The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme including the capability of reducing 5-((4S)-2-oxo-4-phenyl (1,3-oxazolidin-3-yl))-1-(4-fluorophenyl) pentane-1,5-dione to (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize the intermediate (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one in a process for making Ezetimibe.

Abstract: The present invention relates to a device for mounting a shaft of a screen, such as a window covering, on a surface such as a wall, window frame or a ceiling, wherein the device comprises a mounting bracket and a shaft holder, wherein the mounting bracket is configured for mounting on the surface and the shaft holder is attachable to the mounting bracket, wherein the shaft holder is provided with coupling means for coupling the shaft and the shaft holder in releasably attachable manner to the mounting bracket.

Abstract: The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme including the capability of reducing 5-((4S)-2-oxo-4-phenyl(1,3-oxazolidin-3-yl))-1-(4-fluorophenyl)pentane-1,5-dione to (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize the intermediate (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one in a process for making Ezetimibe.

Abstract: The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme including the capability of reducing 5-((4S)-2-oxo-4-phenyl(1,3-oxazolidin-3-yl))-1-(4-fluorophenyl)pentane-1,5-dione to (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize the intermediate (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one in a process for making Ezetimibe.

Abstract: The invention relates to a device (1) for winding up and unwinding raising cords of a screen, comprising: an elongate housing (2); a shaft (3) intended for rotation in the housing; a number of winding rollers (4) which are coaxially mountable on the shaft for winding up and unwinding the raising cords (5) and which are adapted for releasable fastening of the raising cords; a number of winding roller holders (6) for bearing-mounted support of the winding rollers, which winding roller holders are adapted to be received in the housing.

Abstract: A tea pad is provided for preparing tea. More particularly, the tea pad provides at least one consumption unit of tea with the aid of a coffee maker. The coffee maker is provided with a holder for receiving at least one pad filled with a product to be extracted, and means for pressing hot water under pressure through the pad for obtaining an extract of the product while, preferably, the applied pressure of the water is 1-2 bar. The pad is provided with a covering, such as filtering paper which is at least partly transmissive to a liquid such as water and, which is at least virtually non-transmissive to tea. The covering comprises at least one space which is at least partly filled with tea.

Abstract: The invention relates to a process for dehydrating a water-containing medium, said medium being a pressurized gas having a pressure of at least 0.5 MPa, said process comprising:—contacting the water-containing medium with a dry ionic liquid choline salt to dehydrate the water-containing medium; and—separating a dehydrated medium from the hydrated ionic liquid choline salt. Ionic liquid choline salts offer the advantage that they can be regenerated very easily as they are surprisingly heat-stable. Furthermore, these liquid choline salts offer the advantage that they are non-toxic and largely inert. Thus, these ionic liquid choline salts can suitably be used to dehydrate water-containing media that are subsequently employed in the production of foodstuffs, beverages, nutritional formulations, pharmaceutical preparations etc.

Abstract: The invention relates to an emulsifier, a method for preparing said emulsifier, and to its use in various applications, primarily food and cosmetic applications. The invention also relates to the use of said emulsifier for the creation of an elastic, gelled foam. An emulsifier according to the invention is based on a starch which is enzymatically converted, using a specific type of enzyme, and modified in a specific esterification reaction.

Abstract: The invention relates to a method for reducing the oil uptake of extruded and fried food products. The method of the invention comprises partially replacing said cook-up starch and/or instant starch in the ingredients of said food product by, or adding a hydrophobic starch. It has been found that the resulting food products have a remarkable lower tendency to take up oil when being fried.

Abstract: The invention relates to an emulsifier, a method for preparing said emulsifier, and to its use in various applications, primarily food and cosmetic applications. The invention also relates to the use of said emulsifier for the creation of an elastic, gelled foam. An emulsifier according to the invention is based on a starch which is enzymatically converted, using a specific type of enzyme, and modified in a specific esterification reaction.

Abstract: A device (10) for preparing and ejecting polymeric cement made from at least two pre-packaged components comprises a tubular vessel (12) including a first axial end wall (14) having a closed outlet (16), and a second axial end wall (18) having an aperture (20). A first starting component (50) of the polymeric cement is present inside said tubular vessel near the first axial end wall (14) A shaft (22) extends through said aperture (20) of the second axial end wall (18). A piston element (34) comprises a closed container (36) filled with a second starting component (46) of the polymeric cement. The piston element (34) is selectively lockable to the shaft (22). The container has a bore (38) and is slidingly engaged upon said shaft. An agitator element (24) is secured to one end of the shaft (22).

Abstract: Vertebroplasty compositions and methods are provided. By providing an elastic form stable material which is capable of being delivered directly to a specific desired location within a living creature and provides increased strength and rigidity to the injected location, disorders of the vertebrae of a living creature, for example disorders derived from osteoporosis, are able to be effectively treated. In a method embodiment, elastic form stable material is injected directly into a vertebral body to reinforce and strengthen the vertebral body. Other embodiments are also claimed and described.