Patents by Inventor Jan Knol

Jan Knol has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions for reducing oxidative stress
    Publication number: 20250268842
    Abstract: The present invention relates to compositions comprising lutein, non-digestible carbohydrates and at least one of casein phosphopetides or 1,3-dioleoyl-2-palmitoylglycerol.
    Type: Application
    Filed: May 14, 2025
    Publication date: August 28, 2025
    Applicants: N.V. Nutricia, NUTRICIA EARLY LIFE NUTRITION ( SHANGHAI ) CO., LTD.
    Inventors: Ingrid Brunhilde Renes, Gabriël Thomassen, Jan Knol, Thomas Ludwig, Haofang Jin
  • NUTRITIONAL COMPOSITION
    Publication number: 20250212929
    Abstract: A nutritional composition comprising sn-2 palmitic acid and A2 beta-casein for use in improving the gut microbiota in a human subject.
    Type: Application
    Filed: March 10, 2025
    Publication date: July 3, 2025
    Applicants: N.V. Nutricia, NUTRICIA EARLY LIFE NUTRITION (SHANGHAI) CO., LTD.
    Inventors: Sebastian Tims, Thomas Ludwig, Guus Roeselers, Jan Knol, Gregg Ward, Haofang Jin
  • NUTRITIONAL COMPOSITION
    Publication number: 20250205190
    Abstract: A nutritional composition comprising sn-2 palmitic acid and lactoferrin for use in improving the gut microbiota in a human subject.
    Type: Application
    Filed: March 13, 2025
    Publication date: June 26, 2025
    Applicants: N.V. NUTRICIA, NUTRICIA EARLY LIFE NUTRITION (SHANGHAI) CO., LTD.
    Inventors: Sebastian Tims, Thomas Ludwig, Guus Roeselers, Jan Knol, Gregg Ward, Haofang Jin
  • SYNERGISTIC COMPOSITIONS FOR IMPROVING MINERAL BIOACCESSIBILITY
    Publication number: 20250170073
    Abstract: The present invention lies on the field of synergistic compositions for improving mineral bioaccessibility, in particular iron and/or calcium bioaccessibility. The synergistic compositions comprise lutein, casein phosphopeptide or 1,3-dioleoyl-2-palmitoylglycerol, preferably in combination with a non-digestible carbohydrate. The invention further relates to the use of the compositions in preventing and/or treating mineral deficiency and associated conditions, preferably anaemia.
    Type: Application
    Filed: January 28, 2025
    Publication date: May 29, 2025
    Applicants: N.V. NUTRICIA, NUTRICIA EARLY LIFE NUTRITION (SHANGHAI) CO., LTD.
    Inventors: Ingrid Brunhilde RENES, Gabriël THOMASSEN, Jan KNOL, Thomas LUDWIG, Haofang JIN
  • Mix of specific Bifidobacterium species and specific non-digestible oligosaccharides
    Publication number: 20240324644
    Abstract: A consortium of specific probiotic bacteria comprising Bifidobacterium bifidum and Bifidobacterium breve with specific carbohydrate degrading properties, specific human milk oligosaccharide and preferably also beta-galacto-oligosaccharides with a higher degree of polymerization, is particularly effective for improving intestinal microbiota resilience.
    Type: Application
    Filed: June 13, 2024
    Publication date: October 3, 2024
    Applicant: N.V. Nutricia
    Inventors: Cornelus Johannes Petrus van Limpt, Kaouther Ben Amor, Jan Knol, Ana Maria GIL RODRÍGUEZ
  • NUTRITIONAL COMPOSITION FOR IMPROVING INFANT MICROBIOTA
    Publication number: 20240261346
    Abstract: The present invention relates to nutritional compositions comprising non-digestible oligosaccharides and beta-casein comprising at least 75% by weight of a beta-casein variant having a proline at position 67 of the beta-casein amino acid sequence for use in improving gut microbiota of an infant or child, wherein improvement of gut microbiota encompasses increasing Lactobacillus levels. Advantageously, the composition further favors the increase of Bifidobacterium levels and inhibits the growth of opportunistic and/or pathogenic bacteria.
    Type: Application
    Filed: April 18, 2024
    Publication date: August 8, 2024
    Applicant: N.V. Nutricia
    Inventors: Cornelus Johannes Petrus Van Limpt, Joost Willem Gouw, Jan Knol, Sebastian Tims, Kaouther Ben Amor
  • Synbiotic composition for preventing metabolic disorders
    Patent number: 11641868
    Abstract: The invention relates to improved liver health and lipid metabolism later in life upon ingestion of synbiotics early in life.
    Type: Grant
    Filed: December 30, 2019
    Date of Patent: May 9, 2023
    Assignee: N.V. Nutricia
    Inventors: Eefje Engels, Cornelus Johannes Petrus Van Limpt, Annemarie Oosting, Akhtar Raish Oozeer, Jan Knol, Mona Mischke
  • Synbiotic composition for preventing disorders
    Patent number: 11638729
    Abstract: The invention relates to prevention of insulin resistance or low-grade chronic inflammation later in life upon ingestion of synbiotics early in life.
    Type: Grant
    Filed: December 30, 2019
    Date of Patent: May 2, 2023
    Assignee: N.V. Nutricia
    Inventors: Eefje Engels, Cornelus Johannes Petrus Van Limpt, Annemarie Oosting, Akhtar Raish Oozeer, Jan Knol, Mona Mischke
  • Synbiotic composition for preventing metabolic disorders
    Patent number: 11638438
    Abstract: The invention relates to improved liver health and lipid metabolism later in life upon ingestion of synbiotics early in life.
    Type: Grant
    Filed: December 30, 2019
    Date of Patent: May 2, 2023
    Assignee: N.V. Nutricia
    Inventors: Eefje Engels, Cornelus Johannes Petrus Van Limpt, Annemarie Oosting, Akhtar Raish Oozeer, Jan Knol, Mona Mischke
  • Non-digestible oligosaccharides for decreased colonic protein fermentation
    Publication number: 20220248739
    Abstract: The present invention relates to an infant formula comprising non digestible oligosaccharides for reducing or preventing proteolytic fermentation in the gastro-intestinal tract.
    Type: Application
    Filed: May 29, 2020
    Publication date: August 11, 2022
    Applicant: N.V. Nutricia
    Inventors: Jan Knol, Kaouther Ben Amor
  • Synergism of GOS and polyfructose
    Publication number: 20220125826
    Abstract: The present invention relates to the field of prebiotics. Provided are uses for compositions comprising synergistically effective amounts of polyfructose and galactooligosaccharides (GOS).
    Type: Application
    Filed: January 7, 2022
    Publication date: April 28, 2022
    Applicant: N.V. Nutricia
    Inventors: Gelske Speelmans, Maria Johanna Adriana Petronella Govers, Jan Knol, Eric Alexander Franciscus van Tol
  • Nutritional composition comprising urea and non-digestible oligosaccharides
    Publication number: 20210392936
    Abstract: The invention relates to formula comprising a combination of urea and non-digestible oligosaccharides, for improved stimulation of the growth of Bifidobacteria in the intestinal microbiota of infants or young children.
    Type: Application
    Filed: November 1, 2019
    Publication date: December 23, 2021
    Applicant: N.V. Nutricia
    Inventors: Jan Knol, Bernd Stahl, Roger Bongers
  • Risk of allergy and nutrition to reduce that risk
    Publication number: 20210307371
    Abstract: A method to predict the risk of eczema is provided based on differences in the development of microbiota and its metabolites in healthy infants and infants that develop eczema, and nutritional remedies based on this finding, in the form of lactate utilizing bacteria and fibres stimulating lactate utilizing bacteria.
    Type: Application
    Filed: June 18, 2021
    Publication date: October 7, 2021
    Applicant: N.V. Nutricia
    Inventors: Harm Johannes Wopereis, Jan Knol
  • Risk of allergy and nutrition to reduce that risk
    Patent number: 11064722
    Abstract: A method to predict the risk of eczema is provided based on differences in the development of microbiota and its metabolites in healthy infants and infants that develop eczema, and nutritional remedies based on this finding, in the form of lactate utilizing bacteria and fibres stimulating lactate utilizing bacteria.
    Type: Grant
    Filed: June 12, 2017
    Date of Patent: July 20, 2021
    Assignee: N.V. Nutricia
    Inventors: Harm Johannes Wopereis, Jan Knol
  • SYNBIOTIC COMPOSITION FOR PREVENTING METABOLIC DISORDERS
    Publication number: 20200253258
    Abstract: The invention relates to improved liver health and lipid metabolism later in life upon ingestion of synbiotics early in life.
    Type: Application
    Filed: December 30, 2019
    Publication date: August 13, 2020
    Applicant: N.V. NUTRICIA
    Inventors: Eefje ENGELS, Cornelus Johannes Petrus VAN LIMPT, Annemarie OOSTING, Akhtar Raish OOZEER, Jan KNOL, Mona MISCHKE
  • SYNBIOTIC COMPOSITION FOR PREVENTING METABOLIC DISORDERS
    Publication number: 20200254031
    Abstract: The invention relates to improved liver health and lipid metabolism later in life upon ingestion of synbiotics early in life.
    Type: Application
    Filed: December 30, 2019
    Publication date: August 13, 2020
    Applicant: N.V. NUTRICIA
    Inventors: Eefje ENGELS, Cornelus Johannes Petrus VAN LIMPT, Annemarie OOSTING, Akhtar Raish OOZEER, Jan KNOL, Mona MISCHKE
  • SYNBIOTIC COMPOSITION FOR PREVENTING DISORDERS
    Publication number: 20200147154
    Abstract: The invention relates to prevention of insulin resistance or low-grade chronic inflammation later in life upon ingestion of synbiotics early in life.
    Type: Application
    Filed: December 30, 2019
    Publication date: May 14, 2020
    Applicant: N.V. NUTRICIA
    Inventors: Eefje ENGELS, Cornelus Johannes Petrus VAN LIMPT, Annemarie OOSTING, Akhtar Raish OOZEER, Jan KNOL, Mona MISCHKE
  • SYNERGISM OF GOS AND POLYFRUCTOSE
    Publication number: 20200023000
    Abstract: The present invention relates to the field of prebiotics. Provided are uses for compositions comprising synergistically effective amounts of polyfructose and galactooligosaccharides (GOS).
    Type: Application
    Filed: September 27, 2019
    Publication date: January 23, 2020
    Applicant: N.V. Nutricia
    Inventors: Gelske SPEELMANS, Maria Johanna Adriana Petronella GOVERS, Jan KNOL, Eric Alexander Franciscus VAN TOL
  • Synergism of GOS and polyfructose
    Patent number: 10426791
    Abstract: The present invention relates to the field of prebiotics. Provided are uses for compositions comprising synergistically effective amounts of polyfructose and galactooligosaccharides (GOS).
    Type: Grant
    Filed: July 11, 2017
    Date of Patent: October 1, 2019
    Assignee: N.V. Nutricia
    Inventors: Gelske Speelmans, Maria Johanna Adriana Petronella Govers, Jan Knol, Eric Alexander Franciscus Van Tol
  • for the treatment of mastitis
    Patent number: 10420807
    Abstract: The invention relates to a new strain of Lactobacillus salivarius, products containing the new strain, the use thereof in and methods for the treatment and/or prevention of inflammation and/or infection in breast or udder tissue, particularly in a mammary gland of a human female. The inflammation and/or infection is preferably mastitis.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: September 24, 2019
    Assignee: N.V. NUTRICIA
    Inventors: Rocio Martin, Jan Knol, Leonides Fernández Álvarez, Irene Espinosa Martos, Esther Antonia Jiménez Quintana, Juan Miguel Rodríguez Gómez