Patents by Inventor Jan Knol

Jan Knol has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090220639
    Abstract: The present invention provides the use of a composition comprising non-digestible oligosaccharide for the manufacture of a composition for enteral administration to an infant delivered via caesarean section.
    Type: Application
    Filed: October 6, 2006
    Publication date: September 3, 2009
    Applicant: N.V. NUTRICIA
    Inventors: Joachim Schmitt, Bernd Stahl, Jan Knol
  • Publication number: 20090162323
    Abstract: The present invention relates to methods for feeding and to compositions to be administered to infants delivered via caesarian section and in particular to the use of a) at least two different microorganisms; or b) at least one microorganism and at least one indigestible oligosaccharide; or c) at least two different Bifidobacteria species, subspecies or strains for the manufacture of a composition for enteral administration to an infant delivered via caesarean section. Thereby it is possible to stimulate the healthy development of the intestinal flora of said infants.
    Type: Application
    Filed: October 20, 2006
    Publication date: June 25, 2009
    Applicant: N.V. Nutricia
    Inventors: Günther Boehm, Bernd Stahl, Jan Knol
  • Publication number: 20090136468
    Abstract: The present invention relates to the field of human health and uses of L. rhamnosus strains for the preparation of pharmaceutical and nutritional compositions.
    Type: Application
    Filed: October 28, 2005
    Publication date: May 28, 2009
    Inventors: Gelske Speelmans, Adrianus Johannes Maria Vriesema, Jan Knol
  • Publication number: 20090136615
    Abstract: The invention relates to a liquid nutrition comprising short chain fatty acyl chains, polyunsaturated fatty acyl chains, vegetable oil and a non-digestible, fermentable saccharide. The composition is particular suitable for use as an infant nutrition. The composition is also suitable for treatment and/or prevention of gut barrier related disorders.
    Type: Application
    Filed: April 21, 2006
    Publication date: May 28, 2009
    Inventors: Gelske Speelmans, Martine Sandra Alles, Jan Knol
  • Publication number: 20090004164
    Abstract: A composition comprising Bifidobacterium breve, a non-digestible saccharide A and a non-digestible saccharide B, optionally combined with Lactobacillus paracasei and the use of said composition for the treatment and/or prevention of gastrointestinal disorder, immune disorder and/or endocrine disorder.
    Type: Application
    Filed: February 28, 2006
    Publication date: January 1, 2009
    Applicant: N.V. NUTRICIA
    Inventors: Gelske Speelmans, Jan Knol, Monique Haarman, Johan Garssen, Adrianus Johannes Vriesema, Martine Sandra Alles
  • Publication number: 20080199446
    Abstract: The present invention relates to compositions containing probiotic bacteria and uronic acid oligosaccharides. The compositions can suitably be used as infant nutrition and advantageously reduce the incidence of infection.
    Type: Application
    Filed: April 18, 2006
    Publication date: August 21, 2008
    Inventors: Adrianus Johannes Maria Vriesema, Jan Knol, Bernd Stahl
  • Publication number: 20070207132
    Abstract: There is provided a preparation comprising Bifidobacterium breve and a mixture of non-digestible carbohydrates for non- or partially breast-fed infants as well as the use thereof for the treatment or prevention of immune disorder in non- or partially breast-fed infants. Also provided herein are sequence primers and probe for the detection of Bifidobacterium species as well as diagnostic kit thereof.
    Type: Application
    Filed: October 25, 2004
    Publication date: September 6, 2007
    Applicant: N.V. NUTRICIA
    Inventors: Gea Speelmans, Jan Knol, Monique Haarman, Johan Garssen
  • Publication number: 20060194241
    Abstract: Provided herein are sequence primers and probe for the detection of Lactobacillus species as well as diagnostic kit thereof.
    Type: Application
    Filed: February 28, 2006
    Publication date: August 31, 2006
    Inventors: Jan Knol, Monique Haarman
  • Patent number: 5491079
    Abstract: A promoterless foreign gene is intergrated into the lac operon of Streptococcus thermophilus by transforming a host strain of Streptococcus thermophilus with a donor plasmid which does not replicate in the host strain. The donor plasmid includes a vector backbone and a sequence containing a foreign gene operably intergrated into at least a part of the lac operon of the host strain, in front of at least a part of the lacZ gene of the lac operon, and the sequence conserves the frame of the genomic lac operon of the host strain. Cointegrate transformants are identified in which the complete donor plasmid is integrated into the geonomic lac operon of the host strain, and an integrant transformant is then selected, the genome of which does not include the vector backbone of the donor plasmid but does include the foreign gene, which is operably integrated in front of the lacZ gene of the conserved genomic lac operon and which is stably maintained and expressed upon selective pressure on expression of the lacZ gene.
    Type: Grant
    Filed: March 30, 1993
    Date of Patent: February 13, 1996
    Assignee: Nestec S.A.
    Inventors: Jan Knol, Olivier Marciset, Beat Mollet