Abstract: A system for calibration and testing an optical particulate sensor is provided. The system includes a carrier having at least one microtarget that is configured to emulate a particle; a frame, configured to receive the carrier, the frame further configured to position the at least one microtarget to pass through a measurement volume of the optical particulate sensor; a drive, coupled to the frame, that is configured to move the frame such that the at least one microtarget on the carrier moves through three dimensions of the measurement volume, such that a light beam from the optical particulate sensor is reflected/scattered toward the optical particulate sensor; and at least one processor configured to determine one or more characteristics of the at least one microtarget on the carrier based on the reflected/scattered light.

Abstract: A systems of sensors used for navigation in which the system performs real-time dynamic adjustments of the sensor configuration including scan pattern and sensor output characteristics. For an airborne radar system, the radar system may adjust the scan pattern and/or adjust the waveform characteristics based on the phase of flight. Radar waveform characteristics may include frequency, chirp length, modulation type, dwell duration and other characteristics. The scan pattern and radar beam direction may be based on any combination of the transmit beam, or transmit beams, as well as adjustments to receive beams, e.g., by digital beam forming done by signal processing circuitry of the radar system. Similar techniques may also be applied to other sensors or combinations of sensors such as sonar, lidar, visual, infrared, and other sensors.

Abstract: A method includes providing a radar sensor onboard a vehicle, and one or more active radar beacons around a landing site. Each beacon produces a pattern of one or more artificial echoes that is different from a pattern of echoes produced by others of the beacons. The method further includes guiding the vehicle toward the landing site by transmitting radar signals from the radar sensor to an area around the landing site; receiving return signals from the area around the landing site, including ground reflected signals and transmitted signals from each beacon; and determining whether artificial echoes are detected in the received return signals. When artificial echoes are detected, beacon parameters are loaded from an onboard active beacons database; patterns in the artificial echoes are identified and associated with corresponding beacons from the database; and a slant range to each of the beacons is estimated through the patterns.

Abstract: An electromechanical power-split system and a method of operating thereof is provided, with a mechanical drive branch including an internal combustion engine (3), and with an electric drive branch including a first motor-generator block (59) including a first motor-generator (1) and a second motor-generator block (60) including a second motor-generator (2), the first motor-generator (1) is connectable to the internal combustion engine (3) and to the second motor-generator (2). The system includes a planetary gearset (4) with dual planet gears (46) and four input/output members for altering the flow ratio of the mechanical and electric drive branch. Each dual planet gear (46) is connected to the four input/output members, which are a first pair of input/output members formed by a first sun gear (41) and a ring gear (44), and a second pair of input/output members formed by a second sun gear (43) and a planet carrier (45).

Abstract: A radar system with transmitting circuitry to generate a frequency-modulated output that includes an up-chirp and a down-chirp. The radar system includes receiving circuitry configured to: receive radar returns from a target, calculate a first frequency difference based on the up-chirps and calculate a second frequency difference based on the down-chirps. The radar system calculates an unambiguous but coarse estimate of the Doppler frequency shift corresponding to the target radial velocity relative to the radar from the first and second frequency differences. The system also calculates a fine but ambiguous estimate of the Doppler frequency shift by using multiple chirps either from the same triangular waveform or from a separate waveform. The system calculates an unambiguous and accurate Doppler frequency shift estimate for the target by combining the unambiguous but coarse estimate of the Doppler frequency shift and the fine but ambiguous estimate of the Doppler frequency shift.

Abstract: In some examples, a system includes a weather radar device configured to transmit radar signals, receive first reflected radar signals at a first time, and receive second reflected radar signals at a second time. In some examples, the system also includes processing circuitry configured to determine a first magnitude of reflectivity based on the first reflected radar signals and determine a second magnitude of reflectivity based on the second reflected radar signals. In some examples, the processing circuitry is also configured to determine a temporal variance in reflectivity magnitudes based on determining a difference in reflectivity between the first magnitude and the second magnitude. In some examples, the processing circuitry is further configured to determine a presence of ice crystals based on the first magnitude of reflectivity, the second magnitude of reflectivity, and the temporal variance in reflectivity magnitudes.

Abstract: An electromechanical power-split system and a method of operating thereof is provided, with a mechanical drive branch including an internal combustion engine (3), and with an electric drive branch including a first motor-generator block (59) including a first motor-generator (1) and a second motor-generator block (60) including a second motor-generator (2), the first motor-generator (1) is connectable to the internal combustion engine (3) and to the second motor-generator (2). The system includes a planetary gearset (4) with dual planet gears (46) and four input/output members for altering the flow ratio of the mechanical and electric drive branch . Each dual planet gear (46) is connected to the four input/output members, which are a first pair of input/output members formed by a first sun gear (41) and a ring gear (44), and a second pair of input/output members formed by a second sun gear (143) and a planet carrier (45).

Abstract: The present invention is related to a combination comprising a first constituent and a second constituent, wherein the first constituent is a compound having the ability to rearrange a lysosomal protein, wherein the lysosomal protein has a reduced activity, and wherein the second constituent is Ambroxol and/or a derivative of Ambroxol.

Abstract: In some examples, a system includes a weather radar device configured to transmit radar signals, receive first reflected radar signals at a first time, and receive second reflected radar signals at a second time. In some examples, the system also includes processing circuitry configured to determine a first magnitude of reflectivity based on the first reflected radar signals and determine a second magnitude of reflectivity based on the second reflected radar signals. In some examples, the processing circuitry is also configured to determine a temporal variance in reflectivity magnitudes based on determining a difference in reflectivity between the first magnitude and the second magnitude. In some examples, the processing circuitry is further configured to determine a presence of ice crystals based on the first magnitude of reflectivity, the second magnitude of reflectivity, and the temporal variance in reflectivity magnitudes.

Abstract: In some examples, a system is configured for determining an estimated altitude of a melting layer, and the system includes a weather radar device configured to transmit radar signals and receive reflected radar signals. In some examples, the system also includes processing circuitry configured to determine the estimated altitude of the melting layer based on the reflected radar signals.

Abstract: In some examples, a processor is configured to predict the presence of ice crystals (e.g., high altitude ice crystals) in a volume of airspace based on radar reflectivity values and one or more other types of information indicative of weather conditions in the volume of airspace, such as one or more of: ambient air temperature and altitude. For example, the processor may predict the ice crystals presence by at least estimating the iced water content level within a volume of airspace of interest based on radar reflectivity values for the volume of airspace (e.g., stored as in a three-dimensional buffer) and other information indicative of weather conditions of the volume of airspace. The processor may estimate the iced water content level using a model that relates the information indicative of weather conditions in and around the volume of interest to iced water content in the atmosphere.

Abstract: In some examples, a system includes a weather radar device configured to transmit radar signals, receive first reflected radar signals at a first time, and receive second reflected radar signals at a second time. In some examples, the system also includes processing circuitry configured to determine a first magnitude of reflectivity based on the first reflected radar signals and determine a second magnitude of reflectivity based on the second reflected radar signals. In some examples, the processing circuitry is also configured to determine a temporal variance in reflectivity magnitudes based on determining a difference in reflectivity between the first magnitude and the second magnitude. In some examples, the processing circuitry is further configured to determine a presence of ice crystals based on the first magnitude of reflectivity, the second magnitude of reflectivity, and the temporal variance in reflectivity magnitudes.

Abstract: The present invention is related to a compound of formula (I): a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, a metabolite thereof or a prodrug thereof; for use in a method for the treatment and/or prevention of cancer, wherein X is selected from the group consisting of N—R1, O and S; R1 is selected from the group consisting of alkyl, cycloalkyl, aryl, arylalkyl and hydrogen; R2 is selected from the group consisting of indolyl, substituted indolyl, azaindolyl and substituted azaindolyl; and R3 is selected from the group consisting of aryl, substituted aryl, unsubstituted heteroaryl, heterocyclyl and substituted heterocyclyl.

Abstract: In some examples, a system includes a weather radar device configured to transmit radar signals, receive first reflected radar signals at a first time, and receive second reflected radar signals at a second time. In some examples, the system also includes processing circuitry configured to determine a first magnitude of reflectivity based on the first reflected radar signals and determine a second magnitude of reflectivity based on the second reflected radar signals. In some examples, the processing circuitry is also configured to determine a temporal variance in reflectivity magnitudes based on determining a difference in reflectivity between the first magnitude and the second magnitude. In some examples, the processing circuitry is further configured to determine a presence of ice crystals based on the first magnitude of reflectivity, the second magnitude of reflectivity, and the temporal variance in reflectivity magnitudes.

Abstract: In some examples, a system is configured for determining an estimated altitude of a melting layer, and the system includes a weather radar device configured to transmit radar signals and receive reflected radar signals. In some examples, the system also includes processing circuitry configured to determine the estimated altitude of the melting layer based on the reflected radar signals.

Abstract: The present invention is related to a compound of formula (I): a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, a metabolite thereof or a prodrug thereof; for use in a method for the treatment and/or prevention of cancer, wherein X is selected from the group consisting of N—R1, O and S; R1 is selected from the group consisting of alkyl, cycloalkyl, aryl, arylalkyl and hydrogen; R2 is selected from the group consisting of indolyl, substituted indolyl, azaindolyl and substituted azaindolyl; and R3 is selected from the group consisting of aryl, substituted aryl, unsubstituted heteroaryl, heterocyclyl and substituted heterocyclyl.

Abstract: The present invention is related to a compound of formula (I) a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, a metabolite thereof or a prodrug thereof; for use in a method for the treatment and/or prevention of cancer, wherein X is selected from the group consisting of N—R1, O and S; R1 is selected from the group consisting of alkyl, cycloalkyl, aryl, arylalkyl and hydrogen; R2 is selected from the group consisting of indolyl, substituted indolyl, azaindolyl and substituted azaindolyl; and R3 is selected from the group consisting of aryl, substituted aryl, unsubstituted heteroaryl, heterocyclyl and substituted heterocyclyl.

Abstract: The present invention is related to a compound of formula (I): a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, a metabolite thereof or a prodrug thereof; for use in a method for the treatment and/or prevention of leukemia, wherein X is selected from the group consisting of N—R1, O and S; R1 is selected from the group consisting of alkyl, cycloalkyl, aryl, arylalkyl and hydrogen; R2 is selected from the group consisting of indolyl, substituted indolyl, azaindolyl and substituted azaindolyl; and R3 is selected from the group consisting of aryl, substituted aryl, unsubstituted heteroaryl, heterocyclyl and substituted heterocyclyl.

Abstract: In some examples, a processor is configured to predict the presence of ice crystals (e.g., high altitude ice crystals) in a volume of airspace based on radar reflectivity values and one or more other types of information indicative of weather conditions in the volume of airspace, such as one or more of: ambient air temperature and altitude. For example, the processor may predict the ice crystals presence by at least estimating the iced water content level within a volume of airspace of interest based on radar reflectivity values for the volume of airspace (e.g., stored as in a three-dimensional buffer) and other information indicative of weather conditions of the volume of airspace. The processor may estimate the iced water content level using a model that relates the information indicative of weather conditions in and around the volume of interest to iced water content in the atmosphere.

Abstract: Embodiments of the present invention provide improved systems and methods for matching scenes. In one embodiment, a processor for implementing robust feature matching between images comprises: a first process for extracting a first feature set from a first image projection and extracting a second feature set from a second image projection; a memory for storing the first feature set and the second feature set; and a second process for feature matching using invariant mutual relations between features of the first feature set and the second feature set; wherein the second feature set is selected from the second image projection based on the identification of similar descriptive subsets between the second image projection and the first image projection.