Abstract: The present invention is related to a compound of formula (I) a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, a metabolite thereof or a prodrug thereof; for use in a method for the treatment and/or prevention of cancer, wherein X is selected from the group consisting of N—R1, O and S; R1 is selected from the group consisting of alkyl, cycloalkyl, aryl, arylalkyl and hydrogen; R2 is selected from the group consisting of indolyl, substituted indolyl, azaindolyl and substituted azaindolyl; and R3 is selected from the group consisting of aryl, substituted aryl, unsubstituted heteroaryl, heterocyclyl and substituted heterocyclyl.

Abstract: The disclosure relates to a driver assistance system for a motor vehicle. The driver assistance system includes a wrong-way driving detection device that detects underway or imminent wrong-way driving of the motor vehicle. The driver assistance system also includes an output device that outputs a signal to a driver of the motor vehicle indicative of a wrong-way driving detection. The driver assistance system, via the output device, is configured to modify an operating state of the infotainment device according to the wrong-way driving detection.

Abstract: The present invention is related to a compound of formula (I): a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, a metabolite thereof or a prodrug thereof; for use in a method for the treatment and/or prevention of leukemia, wherein X is selected from the group consisting of N—R1, O and S; R1 is selected from the group consisting of alkyl, cycloalkyl, aryl, arylalkyl and hydrogen; R2 is selected from the group consisting of indolyl, substituted indolyl, azaindolyl and substituted azaindolyl; and R3 is selected from the group consisting of aryl, substituted aryl, unsubstituted heteroaryl, heterocyclyl and substituted heterocyclyl.

Abstract: Arrangement of reversing double-flow gearbox for motor vehicles and construction machines, with two branches of output flow, consisting of an input shaft (13) equipped with a tooth wheel, engaged with a tooth wheel of a first disc clutch (1) and with a tooth wheel of a second disc clutch (2), wherein an output shaft (11) of the first disc clutch (1) houses a first set (3) of tooth wheels and a third set (5) of tooth wheels that are engaged through a first synchronization clutch (61) and a second synchronization clutch (62) with a set of tooth wheels arranged on the output shaft (10) of the gearbox, while an output shaft (12) of the second disc clutch (2) houses a second set (4) of tooth wheels and a fourth set (7) of tooth wheels that are engaged through a third synchronization clutch (63) and a fourth synchronization clutch (64) with a set of tooth wheels arranged on the output shaft (10) of the gearbox, wherein the output shaft (11) of the first disc clutch (1) and the output shaft (12) of the second disc c

Abstract: A drive device for a movement unit of a machine tool includes a first toothed element driven by a drive motor and provided as a drive pinion including a first tooth arrangement and a second toothed element provided as a toothed rack including a second tooth arrangement. One of the first and second toothed elements is connected to a machine frame, and the other of the first and second toothed elements is connected to the movement unit. The first and second toothed elements are moved relative to each other along a movement axis of the first and second toothed elements by the drive motor via a meshing between the first and second tooth arrangements and via an engagement between the first and second tooth arrangements along an engagement axis that extends perpendicularly to the movement axis.

Abstract: In some examples, a processor is configured to predict the presence of ice crystals (e.g., high altitude ice crystals) in a volume of airspace based on radar reflectivity values and one or more other types of information indicative of weather conditions in the volume of airspace, such as one or more of: ambient air temperature and altitude. For example, the processor may predict the ice crystals presence by at least estimating the iced water content level within a volume of airspace of interest based on radar reflectivity values for the volume of airspace (e.g., stored as in a three-dimensional buffer) and other information indicative of weather conditions of the volume of airspace. The processor may estimate the iced water content level using a model that relates the information indicative of weather conditions in and around the volume of interest to iced water content in the atmosphere.

Abstract: Embodiments of the present invention provide improved systems and methods for matching scenes. In one embodiment, a processor for implementing robust feature matching between images comprises: a first process for extracting a first feature set from a first image projection and extracting a second feature set from a second image projection; a memory for storing the first feature set and the second feature set; and a second process for feature matching using invariant mutual relations between features of the first feature set and the second feature set; wherein the second feature set is selected from the second image projection based on the identification of similar descriptive subsets between the second image projection and the first image projection.

Abstract: The present invention is related to a compound of formula (I) a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, a metabolite thereof or a prodrug thereof; for use in a method for the treatment and/or prevention of cancer, wherein X is selected from the group consisting of N—R1, O and S; R1 is selected from the group consisting of alkyl, cycloalkyl, aryl, arylalkyl and hydrogen; R2 is selected from the group consisting of indolyl, substituted indolyl, azaindolyl and substituted azaindolyl; and R3 is selected from the group consisting of aryl, substituted aryl, unsubstituted heteroaryl, heterocyclyl and substituted heterocyclyl.

Abstract: The present invention is related to a compound of formula (I): a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, a metabolite thereof or a prodrug thereof; for use in a method for the treatment and/or prevention of leukemia, wherein X is selected from the group consisting of N—R1, O and S; R1 is selected from the group consisting of alkyl, cycloalkyl, aryl, arylalkyl and hydrogen; R2 is selected from the group consisting of indolyl, substituted indolyl, azaindolyl and substituted azaindolyl; and R3 is selected from the group consisting of aryl, substituted aryl, unsubstituted heteroaryl, heterocyclyl and substituted heterocyclyl.

Abstract: A vehicle display system displays approach lights acquired by a vision system overlaid on, and aligned with, a stored synthetic approach light symbol. A stored approach light type that corresponds to the target runway may be verified to match the acquired approach lights. A synthetic approach light symbol that corresponds to the approach light type is chosen and aligned with the approach lights for display.

Abstract: Systems and methods for 3D data based navigation using descriptor vectors are provided. In at least one embodiment, a method for identifying corresponding segments in different frames of data comprises identifying a first segment set in a first frame in multiple frames acquired by at least one sensor, and identifying a second segment set in a second frame in the multiple frames. The method also comprises calculating a first and second set of descriptor vectors, wherein the first and second sets of descriptor vectors comprise a descriptor vector for each segment in the respective first and second segment set, wherein a descriptor vector describes an indexed plurality of characteristics; and identifying corresponding segments by comparing the first set of descriptor vectors against the second set of descriptor vectors, wherein the corresponding segments describe characteristics of the same feature in the environment.

Abstract: Embodiments of the present invention provide improved systems and methods for matching scenes. In one embodiment, a processor for implementing robust feature matching between images comprises: a first process for extracting a first feature set from a first image projection and extracting a second feature set from a second image projection; a memory for storing the first feature set and the second feature set; and a second process for feature matching using invariant mutual relations between features of the first feature set and the second feature set; wherein the second feature set is selected from the second image projection based on the identification of similar descriptive subsets between the second image projection and the first image projection.

Abstract: It is herewith declared that the information stored on the carrier which is submitted together with the international patent application is identical to the written sequence listing of the international patent application.

Abstract: Systems and methods for 3D data based navigation using a watershed method are provided. In at least one embodiment, a method for segmenting three-dimensional frames of data comprises acquiring at least one frame from at least one sensor, wherein the at least one frame provides a three-dimensional description of an environment containing the at least one sensor; and identifying a surface in the at least one frame. The method further comprises computing at least one residual map for the at least one frame based on the orthogonal distance from data points on the surface to at least one polynomial surface fitted to the surface; and segmenting the at least one residual map by performing a watershed algorithm on the residual map.

Abstract: Provided are dies having a first section for orienting material being pressed through the die and a second section for shaping the oriented material into a desired form. In an embodiment, the surface area for shaping the oriented material into a desired form is limited. Also provided are polymer articles and processes for making the same. In an embodiment, the processes employ the dies.

Abstract: Systems and methods for airborne object detection using monocular sensors are provided. In one embodiment, a system for detecting moving objects from a mobile vehicle comprises: an imaging camera; a navigation unit including at least an inertial measurement unit; and a computer system coupled to the image camera and the navigation unit. The computer system executes an airborne object detection process algorithm, and calculates a transformation between two or more image frames captured by the imaging camera using navigation information associated with each of the two or more image frames to generate a motion compensated background image sequence. The computer system detects moving objects from the motion compensated background image sequence.

Abstract: Embodiments of the present invention provide improved systems and methods for matching scenes. In one embodiment, a processor for implementing robust feature matching between images comprises: a first process for extracting a first feature set from a first image projection and extracting a second feature set from a second image projection; a memory for storing the first feature set and the second feature set; and a second process for feature matching using invariant mutual relations between features of the first feature set and the second feature set; wherein the second feature set is selected from the second image projection based on the identification of similar descriptive subsets between the second image projection and the first image projection.

Abstract: In one aspect, an apparatus for use in a wellbore is disclosed that in one non-limiting embodiment may include a drive system coupled to a drill bit by a drive sub for drilling a wellbore, wherein the drive system has an associated bend for directional drilling of the wellbore, and a reamer driven by the drive sub, wherein the reamer reams a ledge formed at a transition from a larger diameter wellbore to a smaller diameter of the wellbore during directional drilling of the wellbore.

Abstract: Arrangement of reversing double-flow gearbox for motor vehicles and construction machines, with two branches of output flow, consisting of an input shaft (13) equipped with a tooth wheel, engaged with a tooth wheel of a first disc clutch (1) and with a tooth wheel of a second disc clutch (2), wherein an output shaft (11) of the first disc clutch (1) houses a first set (3) of tooth wheels and a third set (5) of tooth wheels that are engaged through a first synchronisation clutch (61) and a second synchronisation clutch (62) with a set of tooth wheels arranged on the output shaft (10) of the gearbox, while an output shaft (12) of the second disc clutch (2) houses a second set (4) of tooth wheels and a fourth set (7) of tooth wheels that are engaged through a third synchronisation clutch (63) and a fourth synchronisation clutch (64) with a set of tooth wheels arranged on the output shaft (10) of the gearbox, wherein the output shaft (11) of the first disc clutch (1) and the output shaft (12) of the second disc c

Abstract: A drive device for a movement unit of a machine tool includes a first toothed element driven by a drive motor and provided as a drive pinion including a first tooth arrangement and a second toothed element provided as a toothed rack including a second tooth arrangement. One of the first and second toothed elements is connected to a machine frame, and the other of the first and second toothed elements is connected to the movement unit. The first and second toothed elements are moved relative to each other along a movement axis of the first and second toothed elements by the drive motor via a meshing between the first and second tooth arrangements and via an engagement between the first and second tooth arrangements along an engagement axis that extends perpendicularly to the movement axis.