Abstract: A digitally compensated circuit for a power supply having a plurality of integrated circuits. The plurality of integrated circuits has a digitally variable slope controller to adjust charge time of an inductor and voltage distortion and an adjustable voltage generator, which generates a modified voltage set point. The digitally compensated circuit has a comparator, which compares the modified voltage set point to a first feedback and turns off a comparator output signal when first feedback approaches or exceeds the modified voltage set point. An adjustable pulse width modulator generator produces an output voltage. A current monitor receives output voltage and provides a second feedback, which is transferred to the plurality of integrated circuits. An inductor receives output voltage and generates variable output power for a load, utilizing the digitally variable slope controller to reduce oscillation, system disturbances, and subharmonic oscillations over a dynamic voltage input range.

Abstract: A method of removing an electric crosstalk contribution is disclosed. This crosstalk exists in a monitoring signal from a monitored electro-mechanical transducer in a device comprising a plurality of electro-mechanical transducers which are driven by actuation signals so as to produce acoustic waves in an acoustic frequency range. The method comprises the steps of: (a) applying an actuation signal to at least one of the transducers other than the monitored transducer; (b) detecting the monitoring signal in a high frequency range outside of the acoustic frequency range; (c) deriving, from the detected monitoring signal, a number of parameters that characterize the electric crosstalk; and (d) using said parameters to calculate the electric crosstalk contribution in the acoustic frequency range.

Abstract: A method, system, and computer program product for random number generation using a network of mobile devices are provided in the illustrative embodiments. From a set of mobile devices, a corresponding set of data packets is received. A presence of raw sensor data is detected in a first data packet received from a first mobile device in the set of mobile devices. The raw sensor data comprises data corresponding to changing value of an output of a sensor in a set of sensors installed in the first mobile device. The raw sensor data is separated from the first data packet, resulting in an original data packet. A first random number is generated using the raw sensor data.

Abstract: Methods, computer-readable media, and systems for reflecting changes to graph-structured data are provided. One method for reflecting changes to graph-structured data includes receiving a plot of a number of viewed nodes that are viewed on a first graph, constructing a second graph in response to a change in the graph-structured data associated with the first graph, by determining a number of viewed edges between a first viewed node of the number of viewed nodes and a remainder of the number of viewed nodes, determining a number of node connects for the first viewed node, and providing an indication of completeness of the first viewed node based on whether the number of node connects is greater than the number of viewed edges between the first viewed node and the number of viewed nodes, and merging the first graph and the second graph to create a merged graph.

Abstract: A method, system, and computer program product for random number generation using a network of mobile devices are provided in the illustrative embodiments. From a set of mobile devices, a corresponding set of data packets is received. A presence of raw sensor data is detected in a first data packet received from a first mobile device in the set of mobile devices. The raw sensor data comprises data corresponding to changing value of an output of a sensor in a set of sensors installed in the first mobile device. The raw sensor data is separated from the first data packet, resulting in an original data packet. A first random number is generated using the raw sensor data.

Abstract: A processor chip may have a built-in hardware lock and deterministic exclusive locking of the hardware lock by execution units executing in parallel on the chip. A set of software locks may be maintained, where the execution units set and release the software locks only by first acquiring a lock of the hardware lock. A first execution unit sets a software lock after acquiring a lock of the hardware lock, and other execution units, even if exclusively locking the hardware lock, are unable to lock the software lock until after the first execution unit has reacquired a lock of the hardware lock and possibly released the software lock while exclusively locking the hardware lock. An execution unit may release a software lock after and while holding a lock of the hardware lock. The hardware lock is released when a software lock has been set or released.

Abstract: Methods, computer-readable media, and systems for reflecting changes to graph-structured data are provided. One method for reflecting changes to graph-structured data includes receiving a plot of a number of viewed nodes that are viewed on a first graph, constructing a second graph in response to a change in the graph-structured data associated with the first graph, by determining a number of viewed edges between a first viewed node of the number of viewed nodes and a remainder of the number of viewed nodes, determining a number of node connects for the first viewed node, and providing an indication of completeness of the first viewed node based on whether the number of node connects is greater than the number of viewed edges between the first viewed node and the number of viewed nodes, and merging the first graph and the second graph to create a merged graph.

Abstract: A method is provided for transforming entity and relation data using a proxy engine. A proxy data engine can intercept a virtual query directed to a data provider application on a data repository device. The proxy data engine can transform the virtual query into a native query capable of being processed by the data provider application. The virtual query can include a virtual entity-relation object not included in the native query. The proxy data engine can transform a native result into a virtual result including the virtual entity-relation object. The native result can be a response to the native query and the native result can be received by the data provider application.

Abstract: A processor chip may have a built-in hardware lock and deterministic exclusive locking of the hardware lock by execution units executing in parallel on the chip. A set of software locks may be maintained, where the execution units set and release the software locks only by first acquiring a lock of the hardware lock. A first execution unit sets a software lock after acquiring a lock of the hardware lock, and other execution units, even if exclusively locking the hardware lock, are unable to lock the software lock until after the first execution unit has reacquired a lock of the hardware lock and possibly released the software lock while exclusively locking the hardware lock. An execution unit may release a software lock after and while holding a lock of the hardware lock. The hardware lock is released when a software lock has been set or released.

Abstract: A method and system of maintaining a computing services repository, including: accessing service data stored in a configuration database to populate a services repository with services and the service data from the configuration database; performing on-going service discovery to synchronize the services depository and the configuration database; and managing service data imported to the services repository from the configuration database.

Abstract: Disclosed is a method in which DNA sequences derived from microsome-associated mRNA sequences in a mixed sample or in an arrayed single sequence clone can be determined and classified without sequencing. The methods make use of information on the presence of carefully chosen target subsequences, typically of length from 4 to 8 base pairs, and preferably the length between target subsequences in a sample DNA sequence together with DNA sequence databases containing lists of sequences likely to be present in the sample to determine a sample sequence. The preferred method uses restriction endonucleases to recognize target subsequences and cut the sample sequence. Then carefully chosen recognition moieties are ligated to the cut fragments, the fragments amplified, and the experimental observation made. Polymerase chain reaction (PCR) is the preferred method of amplification.

Abstract: New biochemical protocols for high throughput processing of mRNA samples into cDNA libraries with adaptor sequences compatible with automated sequencing systems are provided. The provided methods produces cDNA libraries which do not have 3? bias associated with current cDNA library production methods. New methods for the production of DNA libraries from DNA are also provided.

Abstract: The present invention provides for a method of preparing a target nucleic acid fragments to produce a smaller nucleic acid which comprises the two ends of the target nucleic acid. Specifically, the invention provides cloning and DNA manipulation strategies to isolate the two ends of a large target nucleic acid into a single small DNA construct for rapid cloning, sequencing, or amplification.

Abstract: The claimed invention provides for new sample preparation methods enabling direct sequencing of PCR products using pyrophosphate sequencing techniques. The PCR products may be specific regions of a genome. The techniques provided in this disclosure allows for SNP (single nucleotide polymorphism) detection, classification, and assessment of individual allelic polymorphisms in one individual or a population of individuals. The results may be used for diagnostic and treatment of patients as well as assessment of viral and bacterial population identification.

Abstract: The invention discloses the use of low molecular weight hyaluronic acid fragments, which can be suitably modified, where appropriate, for producing vaccines. The vaccines are particularly suitable for controlling cancer diseases. Surprisingly, it has been found that low molecular weight hyaluronic acid fragments, which can be suitably modified, where appropriate, can be used both for preparing mature dendritic cells and directly, together with antigens or peptides or carrier systems, as an adjuvant in vaccines. It is likewise possible to couple the low molecular weight hyaluronic acid fragments, which can be suitably modified, where appropriate, to an antigen, peptide or carrier system. The coupled system can then be advantageously employed as a vaccine, in particular for treating cancer diseases.

Abstract: The present invention relates to the use of anti-CD44 antibodies of both the constant (sDC44) and the variable part of CD44 (vCD44) for treating certain tumours and other diseases associated with the degeneration and activation of Langerhans cells (LC) and dendritic cells (DC) inside a mammalian body, including humans, and for treating undesirable immune reactions.

Abstract: A method for determining the activity of a nucleotide polymerizing enzyme in a sample, and use of the method for determining HIV 1 RT- and Herpes Simplex DNA-polymerase activity. The enzyme is captured by means of a nonoclonal antibody which is immobilized to a solid carrier and is capable of binding the enzyme without detrimentally effecting the enzyme activity. Contaminants and disturbing factors are removed and the nucleotide polymerization starts by the addition of a reaction solution containing a primer/template construct and nucleotides substrate, the reaction conditions being chosen such that they promote permanent association between antibody enzyme- and primer/template constructs. When necessary a nucleotide substrate, primer/template and reaction solution are washed away from the newly synthesized polymer, and the amount of nucleotide which as been incorporated into the polymer is determined, and the activity of the enzyme is determined with the guidance of this determination.

Abstract: An apparatus is described for reading a radiation-reflecting record carrier on which information is stored in an optically readable track-shaped phase structure. The apparatus inter alia includes a radiation source, an objective system and a radiation-sensitive detection system. By a suitable arrangement and a suitable choice of the power of a cylindrical lens, which lens in conjunction with a four-quadrant detector supplies a focussing signal, it is possible to detect centering-errors with the aid of only two additional detectors in the plane of the four-quadrant detector.

Abstract: An apparatus is described for reading a record carrier on which information is stored in an optically readable structure. Between a radiation source and an objective system a mirror system is disposed, by means of which the entrance pupil of the objective lens can be imaged onto beam-controlling elements which deflect the read beam over the information structure.

Abstract: An apparatus is described for reading a record carrier on which information is stored in an optically readable structure. Between a radiation source and an objective system, a polarization-sensitive beam splitter and a .lambda./4 plate are disposed. The optic axis of the .lambda./4 plate is perpendicular to the end faces, so that the plate may be thick and may be rotated in its own plane.