Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.

Abstract: Controlling traffic signal preemption includes inputting to a conditional preemption circuit, values of a plurality of incident parameters that include at least a vehicle unit identifier of a vehicle unit and an incident priority that describes an incident. The conditional preemption circuit determines a preemption mode for a vehicle associated with the vehicle unit identifier based on one or more of the plurality of incident parameters. The preemption mode is one of a first mode or a second mode. Traffic signal preemption is enabled for the vehicle unit in response to the conditional preemption circuit determining the first mode. Traffic signal preemption is disabled for the vehicle unit in response to the conditional preemption circuit determining the second mode.

Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.

Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.

Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.

Abstract: Described herein are glucocorticoid receptor modulators and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer and hypercortisolism.

Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.

Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.

Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.

Abstract: Methods and systems for emissions free dispatchable power supply, emissions free chemical energy storage, and emissions free chemical energy distribution are disclosed. Methods include providing water and/or carbon dioxide to an electrolyser; providing electricity from a regional electrical power grid to the electrolyser for electrolysis of the water and/or carbon dioxide to produce oxygen; and providing the oxygen from the electrolyser to a hydrocarbon oxidation device for the oxidation of a hydrocarbon.

Abstract: Systems and methods for providing suggestions responsive to search queries for a search engine are disclosed. Such suggestions may include one or more related search queries and/or a spell correction. Related search queries may be provided by converting the search query into a document vector space, determining documents that are similar to the query in the vector space, and determining prior search queries to which those similar documents are responsive. Spell corrections may be provided by comparing n-tuple word combinations in the search query to a library of correct n-tuple word combinations and making appropriate corrections.

Abstract: A method for operating a search engine may include determining a multi-dimensional search parameter space comprising a set of possible weight values for each of a plurality of search parameters and dividing the search parameter space into a grid of evenly-spaced values that is a subset of the set of possible values. The method may further include defining one or more initial populations of search parameter weight values, wherein each population of search parameter weight values comprises a plurality of initial individuals, wherein each initial individual comprises a respective one of the evenly-spaced values for each of the search parameters. The method may further include executing one or more genetic algorithms based on the one or more initial populations to select a final set of search parameter weight values, and returning results of a user search in the search engine according to the final set of search parameter weight values.

Abstract: A commercial scale system and process for chemically modifying wood and then heating the chemically-modified wood. The system/process separates the chemical modification step from the heating step by utilizing two different vessels for the modification and heating steps. The system and process can, in certain situations, include a containment room for preventing escape of vapors from a chemical wood modification reactor, a wood heater, and/or a chemically-modified bundle of wood as the bundle is transported from the wood modification reactor to the wood heater.

Abstract: A commercial scale system and process for chemically modifying wood and then heating the chemically-modified wood. The system/process separates the chemical modification step from the heating step by utilizing two different vessels for the modification and heating steps. The system and process can, in certain situations, include a containment room for preventing escape of vapors from a chemical wood modification reactor, a wood heater, and/or a chemically-modified bundle of wood as the bundle is transported from the wood modification reactor to the wood heater.

Abstract: A microwave heater equipped with a microwave choke and suitable for heating one or more articles under vacuum. The microwave choke inhibits leakage of microwave energy between a door of the heater and a main vessel body of the heater without causing arcing at the choke, even at low pressures. In certain situations, the microwave choke can be configured with side-by-side choke cavities. In certain situations, the microwave choke can be removably coupled to the door and/or vessel body for easier fabrication, installation, and/or replacement.

Abstract: The present invention is a metal oxygen alarm system that indicates to a user when an oxygen tank is at a predetermined low level that includes an alarm valve that emits a whistle sound that is audible in an ordinary decibel level environment activated when the oxygen tank is at the predetermined low oxygen pressure level and a portable oxygen regulator that has a top inlet and a bottom inlet and is attached to the oxygen tank and regulates an amount of oxygen provided to the user.

Abstract: A microwave heater equipped with a microwave choke and suitable for heating one or more articles under vacuum. The microwave choke inhibits leakage of microwave energy between a door of the heater and a main vessel body of the heater without causing arcing at the choke, even at low pressures. In certain situations, the microwave choke can be configured with side-by-side choke cavities. In certain situations, the microwave choke can be removably coupled to the door and/or vessel body for easier fabrication, installation, and/or replacement.

Abstract: A microwave heater capable of heating a bundle of wood and equipped with an optimized system for introducing microwave energy into the heater. The system uses a high-efficiency elongated waveguide launcher having a plurality of launch openings defined in relatively thin walls. The waveguide launcher can exhibit a launch efficiency of at least 50 percent, thereby providing substantially energy savings over conventional waveguide launchers.

Abstract: A microwave heater equipped with a microwave choke and suitable for heating wood under vacuum. The microwave choke inhibits leakage of microwave energy between a door of the heater and a main vessel body of the heater without causing arcing at the choke, even at low pressures. In certain situations, the microwave choke can be configured with side-by-side choke cavities. In certain situations, the microwave choke can be removably coupled to the door and/or vessel body for easier fabrication, installation, and/or replacement.