Abstract: Disclosed herein are glass pharmaceutical vials having sidewalls of reduced thickness. In embodiments, the glass pharmaceutical vial may include a glass body comprising a sidewall enclosing an interior volume. An outer diameter D of the glass body is equal to a diameter d1 of a glass vial of size X as defined by ISO 8362-1, wherein X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1. However, the sidewall of the glass pharmaceutical vial comprises an average wall thickness Ti that is less than or equal to 0.85*s1, wherein s1 is a wall thickness of the glass vial of size X as defined by ISO 8362-1 and X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1.

Abstract: Disclosed herein are glass pharmaceutical vials having sidewalls of reduced thickness. In embodiments, the glass pharmaceutical vial may include a glass body comprising a sidewall enclosing an interior volume. An outer diameter D of the glass body is equal to a diameter d1 of a glass vial of size X as defined by ISO 8362-1, wherein X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1. However, the sidewall of the glass pharmaceutical vial comprises an average wall thickness Ti that is less than or equal to 0.85*s1, wherein s1 is a wall thickness of the glass vial of size X as defined by ISO 8362-1 and X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1.

Abstract: An autonomous floor cleaner includes multiple occupiable space sensors for position and/or proximity sensing. Data from the occupiable space sensors can be used determine areas of occupiable space in proximity to the autonomous floor cleaner. Methods for exiting a trapped condition, obstacle avoidance, and path planning are disclosed.

Abstract: Disclosed herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, that are inhibitors of Polo Like Kinase 4 (PLK4). Also disclosed herein are pharmaceutical compositions comprising the compounds of Formula (I), or pharmaceutically acceptable salts thereof, and one or more pharmaceutically acceptable excipients. Further disclosed herein are methods of treating cancer in a subject in need thereof, comprising administering to the subject an amount of a compound of Formula (I), or a pharmaceutically acceptable salt thereof.

Abstract: A docking station for charging an autonomous floor cleaner includes a transmitter that can transmit a signal for detection by the robot. The docking station can include an opaque shroud for the transmitter and/or spring-loaded charging contacts. The autonomous floor cleaner can comprise a passive receiver that detects signals emitted from the docking station and a time-of-flight sensor for position/proximity sensing. The robot can selectively turn off the time-of-flight sensor when docking with or avoiding the docking station. Methods for docking, re-docking, low power charging, docking station avoidance, obstacle response during docking, and close-proximity docking are disclosed.

Abstract: A method of operating a device, which includes providing a user interface with a display artifact; in response to an indication a user selected to copy the display artifact, storing multiple levels of detail of the display artifact; allowing the user to paste a selected level of detail by steps of: in response to an indication a user selected an input field and a paste command, displaying a plurality of paste options for pasting the display artifact into the input field, wherein the plurality of paste options each have a unique level of detail for representing the display artifact; allowing the user to select from the plurality of paste options; and in response to an indication a user selected a paste option from the plurality of paste options, pasting the display artifact with a level of detail associated with the selected paste option into the input filed.

Abstract: Disclosed herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, that are inhibitors of Polo Like Kinase 4 (PLK4). Also disclosed herein are pharmaceutical compositions comprising the compounds of Formula (I), or pharmaceutically acceptable salts thereof, and one or more pharmaceutically acceptable excipients. Further disclosed herein are methods of treating cancer in a subject in need thereof, comprising administering to the subject an amount of a compound of Formula (I), or a pharmaceutically acceptable salt thereof.

Abstract: Disclosed herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, that are inhibitors of Polo Like Kinase 4 (PLK4). Also disclosed herein are pharmaceutical compositions comprising the compounds of Formula (I), or pharmaceutically acceptable salts thereof, and one or more pharmaceutically acceptable excipients. Further disclosed herein are methods of treating cancer in a subject in need thereof, comprising administering to the subject an amount of a compound of Formula (I), or a pharmaceutically acceptable salt thereof.

Abstract: A docking station for charging an autonomous floor cleaner includes a transmitter that can transmit a signal for detection by the robot. The docking station can include an opaque shroud for the transmitter and/or spring-loaded charging contacts. The autonomous floor cleaner can comprise a passive receiver that detects signals emitted from the docking station and a time-of-flight sensor for position/proximity sensing. The robot can selectively turn off the time-of-flight sensor when docking with or avoiding the docking station. Methods for docking, re-docking, low power charging, docking station avoidance, obstacle response during docking, and close-proximity docking are disclosed.

Abstract: An autonomous floor cleaner includes multiple occupiable space sensors for position and/or proximity sensing. Data from the occupiable space sensors can be used determine areas of occupiable space in proximity to the autonomous floor cleaner. Methods for exiting a trapped condition, obstacle avoidance, and path planning are disclosed.

Abstract: A system and method for communicatively pairing a mobile communication device and a furniture item, such as a desk or table, includes placing the mobile communication device in a communication zone associated with the furniture item. In response to placing the mobile communication device in the communication zone, a communication link is established between the mobile communication device and a communication circuit of the furniture item. A user interface is then displayed on a display screen of the mobile communication device to show a preset height, such as a standing or sitting height, for the furniture device. When a user selects the preset height, an actuator adjusts the furniture item to the specific height. The communication circuit may use any available wireless communication protocol or circuit.

Abstract: A system and method for communicatively pairing a mobile communication device and a furniture item, such as a desk or table, includes placing the mobile communication device in a communication zone associated with the furniture item. In response to placing the mobile communication device in the communication zone, a communication link is established between the mobile communication device and a communication circuit of the furniture item. A user interface is then displayed on a display screen of the mobile communication device to show a preset height, such as a standing or sitting height, for the furniture device. When a user selects the preset height, an actuator adjusts the furniture item to the specific height. The communication circuit may use any available wireless communication protocol or circuit.

Abstract: A method of communicatively pairing a first furnishing item with a second furnishing item, the method including impacting the first furnishing item against the second furnishing item. The method also includes generating a first output with a first sensor of the first furnishing item in response to an impact between the first furnishing item and the second furnishing item and generating a second output with a second sensor of the second furnishing item in response to the impact between the first furnishing item and the second furnishing item. The method further includes receiving, by a controller, the first output, receiving, by the controller, the second output, and pairing a first communication circuit of the first furnishing item with a second communication circuit of the second furnishing item in response to receiving the second output within a predetermined time of receiving the first output.

Abstract: A method of communicatively pairing a first furnishing item with a second furnishing item, the method including impacting the first furnishing item against the second furnishing item. The method also includes generating a first output with a first sensor of the first furnishing item in response to an impact between the first furnishing item and the second furnishing item and generating a second output with a second sensor of the second furnishing item in response to the impact between the first furnishing item and the second furnishing item. The method further includes receiving, by a controller, the first output, receiving, by the controller, the second output, and pairing a first communication circuit of the first furnishing item with a second communication circuit of the second furnishing item in response to receiving the second output within a predetermined time of receiving the first output.

Abstract: Plasmid vectors and use of plasmid vectors in methods for producing methane and isoprene using Archaea are disclosed. Particularly, plasmid vectors that express isoprene synthase (ispS) are prepared and inserted into methanogens, such as Methanosarcina acetivorans, to allow for co-production of methane and isoprene. In one embodiment, the methods of the present disclosure can be used for wastewater management.

Abstract: A method of operating a desk including receiving, at a desk controller, a message from a chair, and determining a position of a user based on the message. The message includes an indication of a sensed rotation of the chair. The method also includes generating, via the desk controller, a control signal for a motor based on the position of the user. The motor is coupled to a support framework of the desk. The method further includes changing a height of the support framework of the desk according to the control signal.

Abstract: A method of operating a desk including receiving, at a desk controller, a message from a chair, and determining a position of a user based on the message. The message includes an indication of a sensed rotation of the chair. The method also includes generating, via the desk controller, a control signal for a motor based on the position of the user. The motor is coupled to a support framework of the desk. The method further includes changing a height of the support framework of the desk according to the control signal.

Abstract: A portable treestand for hunters includes a one piece supporting platform, seat and post molded from a light weight thermoplastic material. The unitary construction of the platform and seat eliminates a large number of fabrication steps and related fastening techniques and devices used therewith. As a result, the platform and seat are stronger, lighter and more rigid, free from many potentially movable joints, and may be made with an irregular pattern.

Abstract: Plasmid vectors and use of plasmid vectors in methods for producing methane and isoprene using Archaea are disclosed. Particularly, plasmid vectors that express isoprene synthase (ispS) are prepared and inserted into methanogens, such as Methanosarcina acetivorans, to allow for co-production of methane and isoprene. In one embodiment, the methods of the present disclosure can be used for wastewater management.