Patents by Inventor Jaroslav A. Kralovec

Jaroslav A. Kralovec has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090042263
    Abstract: The disclosed matter relates to immobilized enzymes and methods of use thereof.
    Type: Application
    Filed: June 13, 2006
    Publication date: February 12, 2009
    Inventors: Jaroslav A. Kralovec, Weijie Wang
  • Publication number: 20080206316
    Abstract: Disclosed are compounds comprising one or more chromium atoms bonded to one or more fatty acids. Also disclosed are nutritional supplements, pharmaceutical formulations, delivery devices, and foodstuffs comprising the disclosed compounds. Methods of using the disclosed compounds and compositions to improve health are also disclosed.
    Type: Application
    Filed: January 26, 2006
    Publication date: August 28, 2008
    Inventors: Colin Barrow, Jaroslav A. Kralovec, Harry Stephen Ewart
  • Publication number: 20080139649
    Abstract: Disclosed are compounds comprising a benzenediol derivative bound to one or more fatty acids. Also disclosed are nutritional supplements, pharmaceutical formulations, delivery devices, and foodstuffs comprising the disclosed compounds. Methods of using the disclosed compounds and compositions to improve health are also disclosed.
    Type: Application
    Filed: January 17, 2006
    Publication date: June 12, 2008
    Inventors: Colin J. Barrow, Jaroslav A. Kralovec
  • Publication number: 20060217356
    Abstract: Triglycerides and cholesterol in the bloodstream are important factors in the development in the development of cardiovascular disease. The present invention discloses a nutritional supplement comprising a sterol and an omega-3 fatty acid, or an ester thereof, for lowering cholesterol and triglyceride levels in the bloodstream of a subject. Preferably, the sterol and omega-3 fatty acid are together in the form of an ester.
    Type: Application
    Filed: March 8, 2006
    Publication date: September 28, 2006
    Inventors: Jeffrey Wright, Jaroslav Kralovec
  • Patent number: 6998501
    Abstract: Triglycerides and cholesterol in the bloodstream are important factors in the development of cardiovascular disease. The present invention discloses a nutritional supplement comprising a sterol and an omega-3 fatty acid, or an ester thereof, for lowering cholesterol and triglyceride levels in the bloodstream of a subject. Preferably, the sterol and omega-3 fatty acid are together in the form of an ester.
    Type: Grant
    Filed: August 30, 2000
    Date of Patent: February 14, 2006
    Assignee: Ocean Nutrition Canada Limited
    Inventors: Jeffrey L. C. Wright, Jaroslav A. Kralovec
  • Patent number: 6977076
    Abstract: Chlorella extracts containing high molecular weight Chlorella polysaccharide and polysaccharide complexes show immune modulatory, specifically immune stimulatory, activity. The polysaccharide and polysaccharide complexes contain glucose and any combination of: galactose, rhamnose, mannose and arabinose, as well as N-acetyl glucosamine and N-acetyl galactosamine. The extracts may be treated with pronase, DNAse, RNAse and proteases to remove unassociated nucleic acids, ribonucleic acids and proteins. The extracts may also undergo treatment to effect cleavage of specific glycosidic linkages, the linkages being defined by their susceptibility to cleavage by amylase, amyloglucosidase, cellulase or neuraminidase. Chlorella extracts may be administered to a mammal to increase proliferation of splenocytes and increase production of cytokines such as IL-6, IL-10, INF-? and TNF-?. They may be used as a supplement to a vaccination regimen.
    Type: Grant
    Filed: February 19, 2003
    Date of Patent: December 20, 2005
    Assignee: Ocean Nutrition Canada Limited
    Inventor: Jaroslav A. Kralovec
  • Patent number: 6974576
    Abstract: Chlorella extracts containing high molecular weight Chlorella polysaccharide and polysaccharide complexes show immune modulatory, specifically immune stimulatory, activity. The polysaccharide and polysaccharide complexes contain glucose and any combination of: galactose, rhamnose, mannose and arabinose, as well as N-acetyl glucosamine and N-acetyl galactosamine. The extracts may be treated with pronase, DNAse, RNAse and proteases to remove unassociated nucleic acids, ribonucleic acids and proteins. The extracts may also undergo treatment to effect cleavage of specific glycosidic linkages, the linkages being defined by their susceptibility to cleavage by amylase, amyloglucosidase, cellulase or neuraminidase. Chlorella extracts may be administered to a mammal to increase proliferation of splenocytes and increase production of cytokines such as IL-6, IL-10, INF-? and TNF-?. They may be used as a supplement to a vaccination regimen.
    Type: Grant
    Filed: December 8, 2003
    Date of Patent: December 13, 2005
    Assignee: Ocean Nutrition Canada Limited
    Inventor: Jaroslav A. Kralovec
  • Publication number: 20050271791
    Abstract: Triglycerides and cholesterol in the bloodstream are important factors in the development in the development of cardiovascular disease. The present invention discloses a nutritional supplement comprising a sterol and an omega-3 fatty acid, or an ester thereof, for lowering cholesterol and triglyceride levels in the bloodstream of a subject. Preferably, the sterol and omega-3 fatty acid are together in the form of an ester.
    Type: Application
    Filed: July 7, 2005
    Publication date: December 8, 2005
    Inventors: Jeffrey Wright, Jaroslav Kralovec
  • Publication number: 20050175711
    Abstract: Disclosed is a composition from shark cartilage comprising immunoactive proteoglycans and other immunoactive components having a molecular weight greater than about 100 KD, wherein the composition has a uronic acid content of about 0.05-0.5 ?g glucuronic acid per ?g of the composition. The composition may be useful for treating or preventing tumor growth, bacterial infections, viral infections and/or fungal infections.
    Type: Application
    Filed: February 15, 2002
    Publication date: August 11, 2005
    Applicant: Ocean Nutrition Canada Limited
    Inventors: Jaroslav Kralovec, Frank Sing
  • Publication number: 20040081665
    Abstract: Chlorella extracts containing high molecular weight Chlorella polysaccharide and polysaccharide complexes show immune modulatory, specifically immune stimulatory, activity. The polysaccharide and polysaccharide complexes contain glucose and any combination of: galactose, rhamnose, mannose and arabinose, as well as N-acetyl glucosamine and N-acetyl galactosamine. The extracts may be treated with pronase, DNAse, RNAse and proteases to remove unassociated nucleic acids, ribonucleic acids and proteins. The extracts may also undergo treatment to effect cleavage of specific glycosidic linkages, the linkages being defined by their susceptibility to cleavage by amylase, amyloglucosidase, cellulase or neuraminidase. Chlorella extracts may be administered to a mammal to increase proliferation of splenocytes and increase production of cytokines such as IL-6, IL-10, INF-&ggr; and TNF-&agr;. They may be used as a supplement to a vaccination regimen.
    Type: Application
    Filed: December 8, 2003
    Publication date: April 29, 2004
    Inventor: Jaroslav A. Kralovec
  • Publication number: 20030152587
    Abstract: Chlorella extracts containing high molecular weight Chlorella polysaccharide and polysaccharide complexes show immune modulatory, specifically immune stimulatory, activity. The polysaccharide and polysaccharide complexes contain glucose and any combination of: galactose, rhamnose, mannose and arabinose, as well as N-acetyl glucosamine and N-acetyl galactosamine. The extracts may be treated with pronase, DNAse, RNAse and proteases to remove unassociated nucleic acids, ribonucleic acids and proteins. The extracts may also undergo treatment to effect cleavage of specific glycosidic linkages, the linkages being defined by their susceptibility to cleavage by amylase, amyloglucosidase, cellulase or neuraminidase. Chlorella extracts may be administered to a mammal to increase proliferation of splenocytes and increase production of cytokines such as IL-6, IL-10, INF-&ggr; and TNF-&agr;. They may be used as a supplement to a vaccination regimen.
    Type: Application
    Filed: February 19, 2003
    Publication date: August 14, 2003
    Inventor: Jaroslav A. Kralovec
  • Patent number: 6551596
    Abstract: Chlorella fractionated extracts containing high molecular weight Chlorella polysaccharide and polysaccharide complexes show immune modulatory, specifically immune stimulatory activity. The fractionated extracts are obtained by size fractionation of an extract of Chlorella and selecting fractions containing high molecular weight polysaccharides and polysaccharide complexes of about 1×104 Da to about 1×107 Da. A fraction of about 4×106 Da to about 1×107 Da is preferably obtained by size fractionation. The polysaccharide and polysaccharide complexes contain glucose and any combination of: galactose, rhamnose, mannose and arabinose, as well as N-acetyl glucosamine and N-acetyl galactosamine. The extracts may be treated with pronase, DNAse, RNAse and proteases to remove unassociated nucleic acids, ribonucleic acids and proteins.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: April 22, 2003
    Assignee: Ocean Nutrition Canada Limited
    Inventor: Jaroslav A. Kralovec
  • Publication number: 20020031524
    Abstract: Chlorella extracts containing high molecular weight Chlorella polysaccharide and polysaccharide complexes show immune modulatory, specifically immune stimulatory, activity. The polysaccharide and polysaccharide complexes contain glucose and any combination of: galactose, rhamnose, mannose and arabinose, as well as N-acetyl glucosamine and N-acetyl galactosamine. The extracts may be treated with pronase, DNAse, RNAse and proteases to remove unassociated nucleic acids, ribonucleic acids and proteins. The extracts may also undergo treatment to effect cleavage of specific glycosidic linkages, the linkages being defined by their susceptibility to cleavage by amylase, amyloglucosidase, cellulase or neuraminidase. Chlorella extracts may be administered to a mammal to increase proliferation of splenocytes and increase production of cytokines such as IL-6, IL-10, INF-&ggr; and TNF-&agr;. They may be used as a supplement to a vaccination regimen.
    Type: Application
    Filed: August 10, 2001
    Publication date: March 14, 2002
    Inventor: Jaroslav A. Kralovec