Abstract: Systems, methods, and computer program products for monitoring a health condition of a tool. Operational data is collected from a machine while the machine is operating in a predetermined manner with the tool in each of at least two known health conditions. A plurality of features is extracted from the operational data, a training dataset is generated from the extracted features, and an analytic model is trained using the training dataset. The analytic model can then be used to determine the health condition of the tool by providing features extracted from operational data received from one or more field machines to the analytic model. The analytic model may then determine a health condition of the tool in the field machine based on like features extracted from the operational data from the one or more field machines.

Abstract: Systems, methods, and computer program products for remaining useful life prediction. Operational data is collected from a test machine until a component fails, and a training dataset generated from the operational data. The training dataset is used to define and validate a prediction model. Operational data received from one or more field machines is provided to the prediction model. The prediction model then predicts the remaining useful life of the component of the field machine. To reduce the time-to-failure of the component in the test machine, the component may be repeatedly subjected to an accelerated wear cycle. The prediction model may be defined by extracting features from the training dataset. Like features may be extracted from the field dataset and provided to the prediction model as part of the prediction process. The operational data received from the field machines may be used to generate an updated prediction model.

Abstract: The techniques described herein facilitate sharing electronic cloud-based calendars via online application and collaboration services, e.g., Microsoft Office 365®. In an implementation, a method of operating an online application and collaboration service for sharing electronic calendars between mailboxes is disclosed. The method includes receiving a request to share a master calendar owned by a first user of the online application and collaboration service with a second user. The master calendar is stored in the first user's mailbox. The method further includes communicating a response indicating acceptance of the request to share the master calendar, generating a copy of the master calendar in the second user's mailbox, and synching the copy of the master calendar with the master calendar using pre-cached data to populate an initial view.

Abstract: The present invention is directed to methods and dosing regimens for the treatment of depression (preferably, treatment resistant depression), for the treatment of depression in a suicidal patient, and/or for the treatment and/or prevention of suicidality (e.g. suicidal ideations).

Abstract: A system for validating data migrated from a first data store with source data to a second data store for destination data. A comparator is configured to access entity data for a particular entity which has been migrated from a first data store to a second data store. The comparator queries the first data store to a first set of comparison data from the first data store and obtains a second set of comparison data from the second data store. It then compares the first set of data with the second set of data to validate the migration of the data from the first to the second data store.

Abstract: Integrity verification of a containerized application using a block device signature is described. For example, a container deployed to a host system is signed with a single block device signature. The operating system of the host system implements an integrity policy to verify the integrity of the container when the container is loaded into memory and when its program code executes. During such events, the operating system verifies whether the block device signature is valid. If the block device signature is determined to be valid, the operating system enables the program code to successfully execute. Otherwise, the program code is prevented from being executed. By doing so, certain program code or processes that are not properly signed are prevented from executing, thereby protecting the host system from such processes. Moreover, by using a single block device signature for a container, the enforcement of the integrity policy is greatly simplified.

Abstract: Cu-based bulk amorphous alloys in the quaternary Cu—Zr—Hf—Al alloy system are disclosed. A method of casting such alloys and articles comprising such alloys also are disclosed.

Abstract: The present invention provides methods of maintaining stable remission or stable response achieved by a patient with depression following administration of a therapeutically effective amount of esketamine during an initial administration phase, comprising continuing administration of a therapeutically effective amount of esketamine for at least five months during a subsequent administration phase. The present invention also provides methods for the long term treatment of depression in a patient, comprising administering to the patient in need of the treatment a clinically proven safe and clinically proven effective therapeutically effective amount of esketamine for at least six months. In some embodiments, the depression is major depressive disorder or treatment resistant depression.

Abstract: The present invention is directed to methods and dosing regimens for the treatment of depression (preferably, treatment resistant depression), for the treatment of depression in a suicidal patient, and/or for the treatment and/or prevention of suicidality (e.g. suicidal ideations).

Abstract: The present invention is directed to methods and dosing regimens for the treatment of depression (preferably, treatment resistant depression), for the treatment of depression in a suicidal patient, and/or for the treatment and/or prevention of suicidality (e.g. suicidal ideations).

Abstract: There is disclosed in one example a computing apparatus, including: a hardware platform including a processor and a memory; and instructions encoded within the memory to instruct the processor to: provide a permission list; allocate an executable, the executable to have permissions according to the permission list; designate a child object of the executable; allocate a certificate for the child object; and after a system reboot, grant the child object permissions of the executable after validating the certificate.

Abstract: Integrity verification of a containerized application using a block device signature is described. For example, a container deployed to a host system is signed with a single block device signature. The operating system of the host system implements an integrity policy to verify the integrity of the container when the container is loaded into memory and when its program code executes. During such events, the operating system verifies whether the block device signature is valid. If the block device signature is determined to be valid, the operating system enables the program code to successfully execute. Otherwise, the program code is prevented from being executed. By doing so, certain program code or processes that are not properly signed are prevented from executing, thereby protecting the host system from such processes. Moreover, by using a single block device signature for a container, the enforcement of the integrity policy is greatly simplified.

Abstract: The present invention is directed to methods and dosing regimens for the treatment of depression (preferably, treatment resistant depression), for the treatment of depression in a suicidal patient, and/or for the treatment and/or prevention of suicidality (e.g. suicidal ideations).

Abstract: There is disclosed in one example a computing apparatus, including: a hardware platform including a processor and a memory; a whitelist; an updater, the updater being an executable object authorized to modify files within the whitelist and to launch one or more child processes; and instructions encoded within the memory to provide a system management agent to: maintain a chain of trust between the one or more child processes and the updater, wherein the one or more child processes inherit whitelist permissions associated with the updater; and track the chain of trust across a system reboot, including granting a child process the chain of trust after a reboot only if the child process has associated with it a valid certificate.

Abstract: A calendar sharing invitation is received, and a receiver of the information is identified. The calendar sharing information is sent to the receiver, and the sharer's calendar data is synchronized to a computing system corresponding to the receiver. The sharer's calendar data is synchronized to a pre-accept memory, where it is hidden from the receiver until the receiver provides an input indicating that the receiver accepts the calendar sharing invitation. The sharer's calendar data is then exposed to the receiver for interaction by the receiver.

Abstract: An application health monitoring system automatically resolves anomalies arising among clients of a messaging server. The messaging server clients (MSCs) include one or more applications and services included in the applications. The anomalies include MSC anomalies and process starter anomalies. When a messaging session is disconnected due to server restarts, the service may be automatically restarted a predetermined number of times to re-establish the connection. Similarly, if a process starter of a service fails to start up properly, the service can be automatically restarted a predetermined number of times before the anomaly is flagged for human review. The monitoring system also automatically implements rules whenever service configurations are changed in addition to validating web service ports and cloud provider queues.

Abstract: The present invention is directed to methods and dosing regimens for the treatment of depression (preferably, treatment resistant depression), for the treatment of depression in a suicidal patient, and/or for the treatment and/or prevention of suicidality (e.g. suicidal ideations).

Abstract: Availability data caching in, meeting services is provided. In some examples, a list of users whose data is to be cached locally for a user may be determined based on factors such as their relevance to the user, a likelihood of a meeting being requested with the users, a history of common meetings, and similar factors. What type of user data to cache, for how long, at which granularity level, and similar parameters may be determined as well. User data for users from the list may be retrieved on-demand or on a regular basis from server associated with those users and stored at a server or other computing device for the user for fast access when the user requests to schedule a meeting.

Abstract: The present disclosure concerns systems and methods for generating application-control policies. A system may receive application-usage data for a set of devices. The application-usage data may identify binaries with which a user interacted. The system may determine one or more application-usage characteristics for one or more devices in the set of devices based at least in part on the application-usage data and may rely solely on data associated with the binaries with which the user interacted. The system may identify a set of candidate devices based on the one or more application-usage characteristics. The application-usage characteristics may include a measure of distinct applications used during a specified time period and a measure of variability of application usage across a set of specified time periods. The system may generate an application-control policy for the set of candidate devices based on application-usage data for the set of candidate devices.

Abstract: The present invention is directed to methods and dosing regimens for the treatment of depression (preferably, treatment resistant depression), for the treatment of depression in a suicidal patient, and/or for the treatment and/or prevention of suicidality (e.g. suicidal ideations).